Published in Immunol Rev on January 01, 1977
Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man. J Exp Med (1981) 6.82
T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views. J Exp Med (1980) 6.62
Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition. J Exp Med (1978) 6.29
Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice. J Exp Med (1978) 5.48
Impaired resistance to Mycobacterium tuberculosis infection after selective in vivo depletion of L3T4+ and Lyt-2+ T cells. Infect Immun (1987) 3.87
Specific Lyt 123 cells are involved in protection against Listeria monocytogenes and in delayed-type hypersensitivity to listerial antigens. J Exp Med (1979) 3.31
Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1. J Exp Med (1981) 2.66
The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens. J Exp Med (1978) 2.20
Regulated expression of an immunoglobulin kappa gene introduced into a mouse lymphoid cell line. Proc Natl Acad Sci U S A (1982) 2.20
Quantitative assessment of the pool size and subset distribution of cytolytic T lymphocytes within human resting or alloactivated peripheral blood T cell populations. J Exp Med (1983) 2.16
Study on cellular events in postthymectomy autoimmune oophoritis in mice. I. Requirement of Lyt-1 effector cells for oocytes damage after adoptive transfer. J Exp Med (1982) 2.11
Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity. J Exp Med (1981) 1.82
Delineation of human thymocyte differentiation pathways utilizing double-staining techniques with monoclonal antibodies. Clin Exp Immunol (1981) 1.78
Molecular cloning of Lyt-2, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to its human counterpart, Leu-2/T8, and to immunoglobulin variable regions. Proc Natl Acad Sci U S A (1985) 1.53
Expression of Lyt-1 antigen on certain murine B cell lymphomas. J Exp Med (1981) 1.51
TAP, a novel T cell-activating protein involved in the stimulation of MHC-restricted T lymphocytes. J Exp Med (1986) 1.49
Interleukin 2 induction in Lyt 1+ 23- T cells from Listeria monocytogenes-immune mice. Infect Immun (1982) 1.49
Spontaneous release of the Leu-2 (T8) molecule from human T cells. J Exp Med (1983) 1.48
Hematopoietic cell transformation by a murine recombinant retrovirus containing the src gene of Rous sarcoma virus. Proc Natl Acad Sci U S A (1984) 1.34
Direct evidence for binding of CD8 to HLA class I antigens. J Exp Med (1989) 1.24
Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers. J Exp Med (1982) 1.22
Histogenesis of mouse cerebellum in microwell cultures. Cell reaggregation and migration, fiber and synapse formation. J Cell Biol (1977) 1.22
Sequential expression of new gene programs in inducer T-cell clones. Proc Natl Acad Sci U S A (1983) 1.19
Developmental and communicative interrelations of Ly123 and Ly1 cell sets. J Exp Med (1980) 1.19
Expression and function of CD8 in a murine T cell hybridoma. J Exp Med (1987) 1.16
Cloning of two genes that are specifically expressed in activated cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1986) 1.14
Immunochemical analysis of the released Leu-2 (T8) molecule. J Exp Med (1984) 1.13
Conventional antigen and superantigen may be coupled to distinct and cooperative T-cell activation pathways. Proc Natl Acad Sci U S A (1991) 1.12
Developmental interrelationship of specific Lyt 123 and Lyt 1 cell sets in expression of antibacterial immunity to Listeria monocytogenes. Infect Immun (1984) 1.11
Isolation and characterization of the gene for the murine T cell differentiation antigen and immunoglobulin-related molecule, Lyt-2. Nucleic Acids Res (1987) 1.10
T lymphocyte response to H-2 mutants: cytotoxic effectors are Ly-1+2+. Proc Natl Acad Sci U S A (1979) 1.07
Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex. J Exp Med (1980) 1.06
A unique cell-surface protein phenotype distinguishes human small-cell from non-small-cell lung cancer. Proc Natl Acad Sci U S A (1982) 1.05
A specific biosynthetic marker for immature thymic lymphoblasts. Active synthesis of thymus-leukemia antigen restricted to proliferating cells. J Exp Med (1982) 1.05
Differentiation of memory T cells to virus plaque-forming cells and cytotoxic T lymphocytes. J Exp Med (1977) 1.04
Mouse Lyt-2 antigen: evidence for two heterodimers with a common subunit. Proc Natl Acad Sci U S A (1982) 1.01
Formal proof that different-size Lyt-2 polypeptides arise from differential splicing and post-transcriptional regulation. Proc Natl Acad Sci U S A (1986) 1.01
Physiological regulation of antigen binding to T cells: role of a soluble macrophage factor and of interferon. Proc Natl Acad Sci U S A (1977) 1.00
Clonal evolution of myeloma cells leads to quantitative changes in immunoglobulin secretion and surface antigen expression. Proc Natl Acad Sci U S A (1979) 0.97
Functional heterogeneity of L3T4+ T cells in MRL-lpr/lpr mice. L3T4+ T cells suppress major histocompatibility complex-self-restricted L3T4+ T helper cell function in association with autoimmunity. J Exp Med (1988) 0.95
In-vivo modulation of thymus-derived lymphocytes with monoclonal antibodies in mice. I. Effect of anti-Thy-1 antibody on the tissue distribution of lymphocytes. Immunology (1983) 0.94
Four distinct antigen systems on human thymus and T cells defined by monoclonal antibodies: immunohistological and immunochemical studies. Clin Exp Immunol (1983) 0.94
Cell surface polypeptides of murine T-cell clones expressing cytolytic or amplifier activity. Proc Natl Acad Sci U S A (1980) 0.91
Arsonate-specific murine T cell clones. I. Genetic control and antigen specificity. J Exp Med (1983) 0.90
Use of a monoclonal antibody specifically non-reactive with T cells to delineate lymphocyte subpopulations. Immunology (1981) 0.89
Differential regulation of membrane and secretory mu chain synthesis in human beta cell lines. Regulation of membrane mu or secreted mu. J Exp Med (1982) 0.89
Analysis of cell surface proteins delineates a differentiation pathway linking endocrine and nonendocrine human lung cancers. Proc Natl Acad Sci U S A (1983) 0.89
Surface Lyt phenotype of suppressor cells in C57BL/6 mice infected with Mycobacterium lepraemurium. Clin Exp Immunol (1983) 0.87
Molecular cloning of Lyt-3, a membrane glycoprotein marking a subset of mouse T lymphocytes: molecular homology to immunoglobulin and T-cell receptor variable and joining regions. Proc Natl Acad Sci U S A (1987) 0.85
T cell development. Precursors and inducer requirements of helper effector and feedback suppression inducer cell sets. J Exp Med (1981) 0.85
A new class of cell surface antigens. Quantitative absorption studies defining cell-lineage-specific antigens on hemopoietic cells. J Exp Med (1979) 0.83
Human macromolecular insoluble cold globulin (MICG). I. T-cell origin of T-MICG and null cell origin of N-MICG. J Exp Med (1979) 0.81
Thymus independent anti-horse erythrocyte antibody response and suppressor T cells in the Mexican axolotl (Amphibia, Urodela, ambystoma mexicanum). Immunology (1979) 0.80
T cell regulation of polyclonal B cell responsiveness. III. Overt T helper and latent T suppressor activities from distinct subpopulations of unstimulated splenic T cells. J Exp Med (1981) 0.78
Molecular cloning, reconstruction and expression of the gene encoding the alpha-chain of the bovine CD8--definition of three peptide regions conserved across species. Immunology (1992) 0.77
The control of the immune response: the significance of network theories. J Clin Pathol (1979) 0.75
Detection of T cells that secrete molecules which share determinants with antigen-specific T-cell factors. Proc Natl Acad Sci U S A (1981) 0.75
Functional characterization of human thymocyte subpopulations separated by density gradient centrifugation. Clin Exp Immunol (1984) 0.75
A new differentiation antigen (FT-1) shared with fetal thymocytes and leukemic cells in the mouse. J Exp Med (1984) 0.75
Immunological properties of Fc receptor on lymphocytes. VIII. The behaviour of FcR+ and FcR- T cells in cell-mediated immune responses. Immunology (1980) 0.75
Alteration of T cell maturation and proliferation in the mouse thymus induced by serum factors from patients with ulcerative colitis. Clin Exp Immunol (1987) 0.75
Functional subclasses of T-lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen. J Exp Med (1975) 17.16
Functional subclasses of T lymphocytes bearing different Ly antigens. II. Cooperation between subclasses of Ly+ cells in the generation of killer activity. J Exp Med (1975) 13.69
Ly-A and Ly-B: two systems of lymphocyte isoantigens in the mouse. Proc R Soc Lond B Biol Sci (1968) 7.51
Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T cells. J Exp Med (1975) 7.20
Antigens of leukemias induced by naturally occurring murine leukemia virus: their relation to the antigens of gross virus and other murine leukemia viruses. J Exp Med (1966) 6.45
Immunoregulatory circuits among T-cell sets. I. T-helper cells induce other T-cell sets to exert feedback inhibition. J Exp Med (1978) 6.29
The G (Gross) leukemia antigen. Cancer Res (1965) 6.07
The G-IX system. A cell surface allo-antigen associated with murine leukemia virus; implications regarding chromosomal integration of the viral genome. J Exp Med (1971) 6.06
Isolation and characterization of a mouse cDNA clone that expresses mast-cell growth-factor activity in monkey cells. Proc Natl Acad Sci U S A (1984) 5.81
Control of mating preferences in mice by genes in the major histocompatibility complex. J Exp Med (1976) 5.52
Immunoregulatory circuits among T-cell sets. II. Physiologic role of feedback inhibition in vivo: absence in NZB mice. J Exp Med (1978) 5.48
A pseudogene homologous to mouse transplantation antigens: transplantation antigens are encoded by eight exons that correlate with protein domains. Cell (1981) 5.43
Regulation of cellular and humoral immune responses by T-cell subclasses. Cold Spring Harb Symp Quant Biol (1977) 5.21
Surface alloantigens of plasma cells. J Exp Med (1970) 5.19
T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells. J Exp Med (1976) 5.11
Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity. Science (2000) 5.10
Antigenic modulation. Loss of TL antigen from cells exposed to TL antibody. Study of the phenomenon in vitro. J Exp Med (1968) 4.63
Ly antigens as markers for functionally distinct subpopulations of thymus-derived lymphocytes of the mouse. Nature (1975) 4.34
Synergy among lymphoid cells mediating the graft-versus-host response. II. Synergy in graft-versus-host reactions produced by Balb-c lymphoid cells of differing anatomic origin. J Exp Med (1970) 4.14
Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells. Proc Natl Acad Sci U S A (1989) 4.13
Improved complementation in the cytotoxic test. Transplantation (1970) 3.93
Current enigmas in cancer research. Harvey Lect (1973) 3.91
Receptor-ligand interaction between CD44 and osteopontin (Eta-1). Science (1996) 3.84
Synergy among lymphoid cells mediating the graft-versus-host response. 3. Evidence for interaction between two types of thymus-derived cells. J Exp Med (1972) 3.77
Immunological circuits: cellular composition. Fed Proc (1979) 3.72
Inducer T lymphocytes synthesize a factor that stimulates proliferation of cloned mast cells. Nature (1981) 3.71
Precipitating antibody in human serum to an antigen present in cultured burkitt's lymphoma cells. Proc Natl Acad Sci U S A (1966) 3.56
Idiotype-specific T helper cells are required to induce idiotype-positive B memory cells to secrete antibody. Eur J Immunol (1978) 3.55
Antigenic structure of cell surfaces. An immunoferritin study of the occurrence and topography of H-2' theta, and TL alloantigens on mouse cells. J Exp Med (1969) 3.53
Immunoglobulin and other surface antigens of cells of the immune system. J Exp Med (1971) 3.50
An approach to the mapping of antigens on the cell surface. Proc Natl Acad Sci U S A (1968) 3.46
Antigens of tumors and leukemias induced by viruses. Fed Proc (1966) 3.43
Ly-C: a third locus specifying alloantigens expressed only on thymocytes and lymphocytes. Transplantation (1971) 3.42
Genetic linkage relationships of loci specifying differentiation alloantigens in the mouse. Transplantation (1972) 3.34
Biochemical evidence linking the GIX thymocyte surface antigen to the gp69/71 envelope glycoprotein of murine leukemia virus. J Exp Med (1975) 3.31
In-vitro demonstration of thymic hormone in the mouse by conversion of precursor cells into lymphocytes. Lancet (1973) 3.27
Modification of the antigenic structure of the cell membrane by thymus-leukemia (TL) antibody. Proc Natl Acad Sci U S A (1967) 3.26
Recognition among mice. Evidence from the use of a Y-maze differentially scented by congenic mice of different major histocompatibility types. J Exp Med (1979) 3.23
Cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different T-cell subclasses. J Exp Med (1976) 3.21
Molecular mimicry by herpes simplex virus-type 1: autoimmune disease after viral infection. Science (1998) 3.15
Differentiation of T cells induced by preparations from thymus and by nonthymic agents. J Exp Med (1973) 3.12
Relation of GIX antigen of thymocytes to envelope glycoprotein of murine leukemia virus. J Exp Med (1975) 3.06
Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression. J Exp Med (1976) 3.00
Independent differentiative pathways of Ly1 and Ly23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses. J Exp Med (1976) 2.99
Multiple biologic activities of a cloned inducer T-cell population. Proc Natl Acad Sci U S A (1981) 2.95
Mouse isoantigens: separation of soluble TL (thymus-leukemia) antigen from soluble H-2 histocompatibility antigen by column chromatography. J Exp Med (1967) 2.86
Contrasuppression. A novel immunoregulatory activity. J Exp Med (1981) 2.84
Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells. Proc Natl Acad Sci U S A (1975) 2.77
G (Gross) and H-2 cell-surface antigens: location on Gross leukemia cells by electron microscopy with visually labeled antibody. Proc Natl Acad Sci U S A (1970) 2.77
The effects of anti-theta antiserum upon graft-versus-host activity of spleen and lymph node cells. Cell Immunol (1972) 2.69
Distinctive urinary odors governed by the major histocompatibility locus of the mouse. Proc Natl Acad Sci U S A (1981) 2.68
Use of hybrid antibody with anti-gamma-G and anti-ferritin specificities in locating cell surface antigens by electron microscopy. J Exp Med (1968) 2.62
Development and function of subpopulations of thymocytes and T lymphocytes. Prog Allergy (1976) 2.57
Occurrence of natural antibody to the G (gross) leukemia antigen in mice. Cancer Res (1966) 2.57
A cloned MCGF cDNA encodes a multilineage hematopoietic growth factor: multiple activities of interleukin 3. J Immunol (1985) 2.56
Thymus cells of radiation-chimeras: TL phenotype, sensitivity to guinea-pig serum, and origin from donor cells. Nature (1965) 2.54
Immunoregulatory circuits among T-cell sets. Identification of a subpopulation of T-helper cells that induces feedback inhibition. J Exp Med (1978) 2.53
Leukemia-associated transplantation antigens related to murine leukemia virus. The X.1 system: immune response controlled by a locus linked to H-2. J Exp Med (1973) 2.52
Differential cytokine requirements for regulation of autoimmune gastritis and colitis by CD4(+)CD25(+) T cells. J Autoimmun (2001) 2.49
Serologically demonstrable alloantigens of mouse epidermal cells. J Exp Med (1972) 2.48
Induction of T lymphocytes from precursor cells in vitro by a product of the thymus. J Exp Med (1973) 2.43
Group-specific viral antigens in the milk and tissues of mice naturally infected with mammary tumor virus or Gross leukemia virus. Virology (1968) 2.26
Familial imprinting determines H-2 selective mating preferences. Science (1988) 2.25
The biologic significance of alloreactivity. The ontogeny of T-cell sets specific for alloantigens or modified self antigens. J Exp Med (1978) 2.20
Wild-type Gross leukemia virus. I. Soluble antigen (GSA) in the plasma and tissues of infected mice. J Natl Cancer Inst (1968) 2.17
Synergy among lymphoid cells mediating the graft-versus-host response. I. Synergy in graft-versus-host reactions produced by cells from NZB-Bl mice. J Exp Med (1970) 2.15
Cloning of Ly-5 cDNA. Proc Natl Acad Sci U S A (1985) 2.12
Isoantigens of the H-2 and Tla loci of the mouse: interactions affecting their representation on thymocytes. J Exp Med (1968) 2.11
Antigen-specific T lymphocyte clones. I. Characterization of a T lymphocyte clone expressing antigen-specific suppressive activity. J Exp Med (1981) 2.10
Identification of a cell-surface antigen selectively expressed on the natural killer cell. J Exp Med (1977) 1.97
Immunocompetent cells among mouse thymocytes: a minor population. Science (1971) 1.95
Biological expression of antigenic determinants of murine leukemia virus proteins gp69-71 and p30. J Virol (1974) 1.95
Rejection of skin allografts by radiation chimaeras: selective gene action in the specification of cell surface structure. Nature (1970) 1.95
Use of cloned populations of mouse lymphocytes to analyze cellular differentiation. Cell (1981) 1.95
Identification of a B-cell surface structure involved in antigen-dependent triggering: absence of this structure on B cells from CBA/N mutant mice. J Exp Med (1977) 1.95
Two L-asparaginases from Escherichia coli B. Their separation, purification, and antitumor activity. Biochemistry (1967) 1.95
Mast cell clones: a model for the analysis of cellular maturation. J Cell Biol (1982) 1.91
Inhibition of leukemias in man by L-asparaginase. Cancer Res (1967) 1.88
Antigen-specific T lymphocyte clones. II. Purification and biological characterization of an antigen-specific suppressive protein synthesized by cloned T cells. J Exp Med (1981) 1.86
Preparation of lymphocyte-specific antibody from anti-lymphocyte serum. Lancet (1968) 1.85
Suspension culture of a pigment-producing cell line derived from a human malignant melanoma. J Natl Cancer Inst (1968) 1.84
Recognition of H-2 types in relation to the blocking of pregnancy in mice. Science (1983) 1.83
New visual markers of antibody for electron microscopy. Nature (1969) 1.83
Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes. J Immunol (1975) 1.79
Wild-type Gross leukemia virus. II. Influence of immunogenetic factors on natural transmission and on the consequences of infection. J Natl Cancer Inst (1968) 1.79
Sensory distinction between H-2b and H-2bm1 mutant mice. Proc Natl Acad Sci U S A (1983) 1.79
Regulation of the immune response by subclasses of T lymphocytes. II. The effect of adult thymectomy upon humoral and cellular responses in mice. Eur J Immunol (1975) 1.79
Variations among sublines of inbred AKR mice. Nat New Biol (1973) 1.78
Genetic control of immunoregulatory circuits. Genes linked to the Ig locus govern communication between regulatory T-cell sets. J Exp Med (1979) 1.77
Structural similarities between a product of the T/t-locus isolated from sperm and teratoma cells, and H-2 antigens isolated from splenocytes. Proc Natl Acad Sci U S A (1975) 1.76