Southern blot analysis of DNA extracted from formalin-fixed pathology specimens.

PubWeight™: 3.95‹?› | Rank: Top 1%

🔗 View Article (PMID 3009004)

Published in Cancer Res on June 01, 1986

Authors

L Dubeau, L A Chandler, J R Gralow, P W Nichols, P A Jones

Articles citing this

Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction. J Exp Med (1988) 9.10

Tissue extraction of DNA and RNA and analysis by the polymerase chain reaction. J Clin Pathol (1990) 3.30

Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin-embedded tumor samples. Am J Pathol (1994) 2.86

Antigen retrieval immunohistochemistry: review and future prospects in research and diagnosis over two decades. J Histochem Cytochem (2011) 2.70

Chlamydia pneumoniae (TWAR) in coronary arteries of young adults (15-34 years old). Proc Natl Acad Sci U S A (1995) 2.15

Simplified procedures for applying the polymerase chain reaction to routinely fixed paraffin wax sections. J Clin Pathol (1991) 1.81

DNA extraction from archival formalin-fixed, paraffin-embedded tissues: heat-induced retrieval in alkaline solution. Histochem Cell Biol (2004) 1.77

Application of a polymerase chain reaction for the detection of Mycobacterium leprae in skin tissues. J Clin Microbiol (1991) 1.70

Comparison of clinical targeted next-generation sequence data from formalin-fixed and fresh-frozen tissue specimens. J Mol Diagn (2013) 1.59

Rapid techniques for DNA extraction from routinely processed archival tissue for use in PCR. J Clin Pathol (1994) 1.59

Assessment of Telomere Length in Archived Formalin-Fixed, Paraffinized Human Tissue Is Confounded by Chronological Age and Storage Duration. PLoS One (2016) 1.38

Use of paraffin wax embedded bone marrow trephine biopsy specimens as a source of archival DNA. J Clin Pathol (1992) 1.31

Fundamental study on the mechanism of DNA degradation in tissues fixed in formaldehyde. J Clin Pathol (1990) 1.30

Amplification of whole tumor genomes and gene-by-gene mapping of genomic aberrations from limited sources of fresh-frozen and paraffin-embedded DNA. J Mol Diagn (2005) 1.29

Conversions of formaldehyde-modified 2'-deoxyadenosine 5'-monophosphate in conditions modeling formalin-fixed tissue dehydration. J Histochem Cytochem (2005) 1.21

Detection of hepatitis C virus RNA using ligation-dependent polymerase chain reaction in formalin-fixed, paraffin-embedded liver tissues. Am J Pathol (1996) 1.12

Effective testing of gene-disease associations. Am J Hum Genet (1990) 1.05

Studies on immunoglobulin gene rearrangement in formalin-fixed, paraffin-embedded pathology specimens. Am J Pathol (1988) 1.04

Effects of fixation on polymerase chain reaction detection of Mycobacterium leprae. J Clin Microbiol (1992) 1.03

Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors. BMC Med Genet (2010) 1.01

Buffered formalin is the superior fixative for the detection of HPV DNA by in situ hybridization analysis. Am J Pathol (1989) 0.97

Hepatitis B virus infection associated with hematopoietic tumors. Am J Pathol (1994) 0.96

Novel enzyme immunoassay and optimized DNA extraction for the detection of polymerase-chain-reaction-amplified viral DNA from paraffin-embedded tissue. Am J Pathol (1997) 0.96

Fixation conditions for DNA and RNA in situ hybridization: a reassessment of molecular morphology dogma. Am J Pathol (1998) 0.95

The AMeX method: a multipurpose tissue-processing and paraffin-embedding method. II. Extraction of spooled DNA and its application to Southern blot hybridization analysis. Am J Pathol (1990) 0.93

Different Epstein-Barr virus expression in lymphomas from immunocompromised and immunocompetent patients. Am J Pathol (1990) 0.93

The absence of Harvey ras mutations during development and progression of squamous cell carcinomas of the head and neck. Br J Cancer (1993) 0.91

Is herpes simplex virus associated with peptic ulcer disease? J Virol (1990) 0.89

Alterations of oncogenes in metastatic tumours of human gastric carcinomas. Br J Cancer (1990) 0.89

DNA amplification by polymerase chain reaction from brain tissues embedded in paraffin. Int J Exp Pathol (1993) 0.89

Use of immunocytochemistry and biotinylated in situ hybridisation for detecting measles virus in central nervous system tissue. J Clin Pathol (1990) 0.85

Formalin-fixed paraffin-embedded tissue as a source for quantitation of carcinogen DNA adducts: aristolochic acid as a prototype carcinogen. Carcinogenesis (2014) 0.85

HPV subtypes in cervical cancer biopsies between 1930 and 2004: detection using general primer pair PCR and sequencing. Virchows Arch (2006) 0.85

Newly discovered KI, WU, and Merkel cell polyomaviruses: no evidence of mother-to-fetus transmission. Virol J (2010) 0.84

Comparison of fixatives and fixation time for PCR detection of Mycobacterium in zebrafish Danio rerio . Dis Aquat Organ (2013) 0.81

Beyond laser microdissection technology: follow the yellow brick road for cancer research. Am J Cancer Res (2014) 0.81

Non-Hodgkin's lymphoma involving the brain. Diagnostic usefulness of stereotactic needle biopsy in combination with paraffin-section immunohistochemistry. Acta Neuropathol (1989) 0.81

New Approaches for Biomonitoring Exposure to the Human Carcinogen Aristolochic Acid. Toxicol Res (Camb) (2015) 0.80

Detection of cytomegalovirus infection by means of DNA isolated from paraffin-embedded tissues and dot hybridization. Am J Pathol (1987) 0.79

A simple method for PCR based analyses of immunohistochemically stained, microdissected, formalin fixed, paraffin wax embedded material. Mol Pathol (1999) 0.75

Sizing femtogram amounts of dsDNA by single-molecule counting. Nucleic Acids Res (2015) 0.75

Use of magnetic beads for tissue DNA extraction and IS6110 Mycobacterium tuberculosis PCR. Mol Pathol (1999) 0.75

Lymphocyte gene rearrangement studies in formalin-fixed, paraffin-embedded pathology specimens. West J Med (1988) 0.75

Haplotype analysis in prenatal diagnosis and carrier identification of Salla disease. J Med Genet (1996) 0.75

Degradation and half-life of DNA present in biomass from a genetically-modified organism during land application. J Ind Microbiol Biotechnol (2016) 0.75

Direct-to-PCR tissue preservation for DNA profiling. Int J Legal Med (2015) 0.75

Articles by these authors

Cellular differentiation, cytidine analogs and DNA methylation. Cell (1980) 10.15

Multiple new phenotypes induced in 10T1/2 and 3T3 cells treated with 5-azacytidine. Cell (1979) 6.47

Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int J Cancer (1995) 5.24

5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science (1990) 4.80

The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors. Nucleic Acids Res (1999) 4.74

Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res (1997) 4.65

Accumulation of nuclear p53 and tumor progression in bladder cancer. N Engl J Med (1994) 4.34

Methylation of the 5' CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing. Cancer Res (1995) 4.28

Increased cell division as a cause of human cancer. Cancer Res (1990) 3.38

5-methylcytosine, gene regulation, and cancer. Adv Cancer Res (1983) 3.27

High frequency of acute promyelocytic leukemia among Latinos with acute myeloid leukemia. Blood (1996) 3.24

Inhibition of DNA methylation by 5-aza-2'-deoxycytidine suppresses the growth of human tumor cell lines. Cancer Res (1998) 2.83

Predicting survival using simple clinical variables: a case study in traumatic brain injury. J Neurol Neurosurg Psychiatry (1999) 2.83

Altering gene expression with 5-azacytidine. Cell (1985) 2.79

DNA methylation decreases in aging but not in immortal cells. Science (1983) 2.67

DNA methylation: past, present and future directions. Carcinogenesis (2000) 2.58

Cytosine methylation does not affect binding of transcription factor Sp1. Proc Natl Acad Sci U S A (1988) 2.56

The human ARF cell cycle regulatory gene promoter is a CpG island which can be silenced by DNA methylation and down-regulated by wild-type p53. Mol Cell Biol (1998) 2.53

p16 gene in uncultured tumours. Nature (1994) 2.47

Functional striated muscle cells from non-myoblast precursors following 5-azacytidine treatment. Nature (1977) 2.44

The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res (1994) 2.37

Role of intracranial pressure monitoring in severely head-injured patients without signs of intracranial hypertension on initial computerized tomography. J Neurosurg (1994) 2.36

Detection of ras point mutations by polymerase chain reaction using mutation-specific, inosine-containing oligonucleotide primers. Biochem Biophys Res Commun (1989) 2.35

Altered chromatin structure associated with methylation-induced gene silencing in cancer cells: correlation of accessibility, methylation, MeCP2 binding and acetylation. Nucleic Acids Res (2001) 2.27

Relation of body mass index to tumor markers and survival among young women with invasive ductal breast carcinoma. Cancer (2001) 2.25

Parental imprinting: potentially active chromatin of the repressed maternal allele of the mouse insulin-like growth factor II (Igf2) gene. Genes Dev (1992) 2.19

Susceptibility of nonpromoter CpG islands to de novo methylation in normal and neoplastic cells. J Natl Cancer Inst (2001) 2.13

Angiogenesis in bladder cancer: relationship between microvessel density and tumor prognosis. J Natl Cancer Inst (1995) 2.10

High frequency mutagenesis by a DNA methyltransferase. Cell (1992) 2.08

Effect of p21WAF1/CIP1 expression on tumor progression in bladder cancer. J Natl Cancer Inst (1998) 2.07

Degradation of connective tissue matrices by macrophages. I. Proteolysis of elastin, glycoproteins, and collagen by proteinases isolated from macrophages. J Exp Med (1980) 2.00

Specific genetic analysis of microscopic tissue after selective ultraviolet radiation fractionation and the polymerase chain reaction. Am J Pathol (1992) 1.91

Mechanism of action of eukaryotic DNA methyltransferase. Use of 5-azacytosine-containing DNA. J Mol Biol (1982) 1.89

PAX6 methylation and ectopic expression in human tumor cells. Int J Cancer (2000) 1.87

p53 nuclear protein accumulation correlates with mutations in the p53 gene, tumor grade, and stage in bladder cancer. Am J Pathol (1993) 1.85

High-titer HER-2/neu protein-specific antibody can be detected in patients with early-stage breast cancer. J Clin Oncol (1997) 1.84

Cell cycle-specific reactivation of an inactive X-chromosome locus by 5-azadeoxycytidine. Proc Natl Acad Sci U S A (1982) 1.84

Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancer. Hum Mol Genet (2001) 1.83

The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcome. Br J Cancer (2007) 1.78

Phenotypic conversion of cultured mouse embryo cells by aza pyrimidine nucleosides. Dev Biol (1978) 1.76

Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer. Mol Cell Biol (1994) 1.74

A psychogeriatric survey of old people's homes. Br Med J (Clin Res Ed) (1981) 1.74

The role of DNA methylation in expression of the p19/p16 locus in human bladder cancer cell lines. Cancer Res (1998) 1.73

Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cells. Nucleic Acids Res (2000) 1.73

Changes in the allelic methylation patterns of c-H-ras-1, insulin and retinoblastoma genes in human development. Dev Suppl (1990) 1.73

DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. J Biol Chem (1986) 1.72

Glycoprotein, elastin, and collagen secretion by rat smooth muscle cells. Proc Natl Acad Sci U S A (1979) 1.71

Hemimethylated duplex DNAs prepared from 5-azacytidine-treated cells. Nucleic Acids Res (1981) 1.70

Inhibition of DNA methylation by chemical carcinogens in vitro. Cell (1983) 1.68

Allelic losses of chromosomes 9, 11, and 17 in human bladder cancer. Cancer Res (1990) 1.67

Granulocyte-macrophage colony-stimulating factor: an effective adjuvant for protein and peptide-based vaccines. Blood (1996) 1.66

Potential role of the inactivated X chromosome in ovarian epithelial tumor development. J Natl Cancer Inst (1996) 1.65

Involvement of DNA methylation in human carcinogenesis. Biol Chem (1998) 1.65

Head injury in the elderly. Age Ageing (1986) 1.65

Scar formation after stereotactic vacuum-assisted core biopsy of benign breast lesions. Clin Radiol (2006) 1.60

Destruction of extracellular matrices containing glycoproteins, elastin, and collagen by metastatic human tumor cells. Cancer Res (1980) 1.59

Immunity to oncogenic proteins. Immunol Rev (1995) 1.58

Prescription of oxygen concentrators: adherence to published guidelines. Thorax (1989) 1.57

Genetic disparity between morphologically benign cysts contiguous to ovarian carcinomas and solitary cystadenomas. J Natl Cancer Inst (1995) 1.57

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis. Cell Death Differ (2009) 1.55

Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Res (1997) 1.51

DNA methylation differences associated with tumor tissues identified by genome scanning analysis. Genomics (1998) 1.51

Contiguous patches of normal human mammary epithelium derived from a single stem cell: implications for breast carcinogenesis. Cancer Res (1996) 1.51

HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair. Nucleic Acids Res (1995) 1.50

Zebularine: a new drug for epigenetic therapy. Biochem Soc Trans (2004) 1.49

Roles of cell division and gene transcription in the methylation of CpG islands. Mol Cell Biol (1999) 1.49

Fibrinolytic activity in a human fibrosarcoma cell line and evidence for the induction of plasminogen activator secretion during tumor formation. Cell (1975) 1.48

DNA methylation and cancer. Cancer Res (1986) 1.47

Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene (2006) 1.46

p53 protein and gene alterations in pathological stage C prostate carcinoma. J Urol (1997) 1.45

Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression. J Natl Cancer Inst (1997) 1.45

Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis (1997) 1.43

Glasgow Outcome Scale: an inter-rater reliability study. Brain Inj (1993) 1.42

Change in serum hyaluronan: a simple index of short-term drug-induced changes in hepatic sinusoidal perfusion. Gastroenterology (1993) 1.41

Field evaluation of an albendazole intraruminal capsule against benzimidazole-resistant Haemonchus contortus. Vet Rec (1992) 1.40

Initial experience of intramammary prostheses in breast conservation surgery. Eur J Surg Oncol (1999) 1.38

Mutagenic and epigenetic effects of DNA methylation. Mutat Res (1997) 1.38

Ferritinaemia in leukaemia and Hodgkin's disease. Br J Cancer (1973) 1.37

p53 and treatment of bladder cancer. Nature (1997) 1.36

Matrix immobilization enhances the tissue repair activity of growth factor gene therapy vectors. Hum Gene Ther (2001) 1.36

18fluorodeoxyglucose positron emission tomography to detect mediastinal or internal mammary metastases in breast cancer. J Clin Oncol (2001) 1.35

Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells. Nucleic Acids Res (1986) 1.34

Monitoring the response of patients with locally advanced breast carcinoma to neoadjuvant chemotherapy using [technetium 99m]-sestamibi scintimammography. Cancer (1999) 1.33

In vitro correlates of transformation in C3H/10T1/2 clone 8 mouse cells. Cancer Res (1976) 1.33

Low frequency of p16/CDKN2A methylation in sporadic melanoma: comparative approaches for methylation analysis of primary tumors. Cancer Res (1997) 1.33

Changes in phenotypic expression in embryonic and adult cells treated with 5-azacytidine. J Cell Physiol (1982) 1.32

Distinct pattern of p53 mutations in bladder cancer: relationship to tobacco usage. Cancer Res (1993) 1.32

Allele-specific methylation of the human c-Ha-ras-1 gene. Cell (1987) 1.31

Temporal acquistion of enhanced fibrinolytic activity by syrian hamster embryo cells following treatment with benzo(a)pyrene. Cancer Res (1977) 1.31

Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential. Mutat Res (1999) 1.30

Microsatellite instability in bladder cancer. Cancer Res (1993) 1.29

DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene. Oncogene (1997) 1.29

Critical thresholds of intracranial pressure and cerebral perfusion pressure related to age in paediatric head injury. J Neurol Neurosurg Psychiatry (2005) 1.28

Distinction of low grade from high grade human ovarian carcinomas on the basis of losses of heterozygosity on chromosomes 3, 6, and 11 and HER-2/neu gene amplification. Cancer Res (1991) 1.27