Published in J Biol Chem on May 15, 1986
The Na+-Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi. Am J Physiol Renal Physiol (2008) 2.12
Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP). Bone (2004) 1.57
Regulation of phosphate transport in proximal tubules. Pflugers Arch (2008) 1.33
Pharmacokinetics of foscarnet and distribution to cerebrospinal fluid after intravenous infusion in patients with human immunodeficiency virus infection. Antimicrob Agents Chemother (1989) 1.21
Elevated inorganic phosphate stimulates Akt-ERK1/2-Mnk1 signaling in human lung cells. Am J Respir Cell Mol Biol (2006) 1.14
Elevated phosphate activates N-ras and promotes cell transformation and skin tumorigenesis. Cancer Prev Res (Phila) (2010) 1.07
Regulation of bone-renal mineral and energy metabolism: the PHEX, FGF23, DMP1, MEPE ASARM pathway. Crit Rev Eukaryot Gene Expr (2012) 1.03
Radiation-inactivation studies on brush-border-membrane vesicles. General considerations, and application to the glucose and phosphate carriers. Biochem J (1988) 1.01
Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability. PLoS One (2011) 0.99
The chicken or the egg: PHEX, FGF23 and SIBLINGs unscrambled. Cell Biochem Funct (2012) 0.96
Substrate interactions of the electroneutral Na+-coupled inorganic phosphate cotransporter (NaPi-IIc). J Physiol (2009) 0.93
GALNT3, a gene associated with hyperphosphatemic familial tumoral calcinosis, is transcriptionally regulated by extracellular phosphate and modulates matrix metalloproteinase activity. Biochim Biophys Acta (2008) 0.92
ASARM peptides: PHEX-dependent and -independent regulation of serum phosphate. Am J Physiol Renal Physiol (2010) 0.92
The molecular basis for Na-dependent phosphate transport in human erythrocytes and K562 cells. J Gen Physiol (2000) 0.88
Sirolimus induced phosphaturia is not caused by inhibition of renal apical sodium phosphate cotransporters. PLoS One (2012) 0.87
Acute parathyroid hormone differentially regulates renal brush border membrane phosphate cotransporters. Pflugers Arch (2010) 0.85
Regulation of sodium-dependent phosphate transport in osteoclasts. J Clin Invest (1997) 0.84
Preparation and characterization of basolateral plasma-membrane vesicles from sheep parotid glands. Mechanisms of phosphate and D-glucose transport. Biochem J (1991) 0.81
Chemoprotective effect of taurine on potassium bromate-induced DNA damage, DNA-protein cross-linking and oxidative stress in rat intestine. PLoS One (2015) 0.80
Reconstitution and characterization of a Na+/Pi co-transporter protein from rabbit kidney brush-border membranes. Biochem J (1992) 0.77
Reconstitution of the renal brush-border membrane sodium/phosphate co-transporter. Biochem J (1991) 0.75
Inhibitors of cyclic nucleotide phosphodiesterase isozymes block renal tubular cell proliferation induced by folic acid. J Lab Clin Med (1997) 1.52
Nicotinate adenine dinucleotide phosphate (NAADP) triggers a specific calcium release system in sea urchin eggs. J Biol Chem (1995) 1.38
Nicotinate-adenine dinucleotide phosphate-induced Ca(2+)-release does not behave as a Ca(2+)-induced Ca(2+)-release system. Biochem J (1996) 1.29
Cellular actions of vasopressin in the mammalian kidney. Kidney Int (1976) 1.15
Blunted cGMP response to agonists and enhanced glomerular cyclic 3',5'-nucleotide phosphodiesterase activities in experimental congestive heart failure. Kidney Int (1996) 1.15
Modulation of cyclic nucleotides in islated rat glomeruli: role of histamine, carbamylcholine, parathyroid hormone, and angiotensin-II. J Clin Invest (1978) 1.08
Effect of histamine and its methyl derivatives on cyclic AMP metabolism in gastric mucosa and its blockade by an H2 receptor antagonist. J Clin Invest (1974) 1.08
Possible role of nicotinamide adenine dinucleotide as an intracellular regulator of renal transport of phosphate in the rat. J Clin Invest (1981) 1.06
Pathogenesis of nephrogenic diabetes insipidus due to chronic administration of lithium in rats. J Clin Invest (1985) 1.05
Impaired urinary concentrating ability and cyclic AMP in K+-depleted rat kidney. Am J Physiol (1976) 1.04
Enzymatic synthesis and degradation of nicotinate adenine dinucleotide phosphate (NAADP), a Ca(2+)-releasing agonist, in rat tissues. Biochem Biophys Res Commun (1995) 1.04
Glucagon-sensitive adenylate cyclase in human renal medulla. J Clin Endocrinol Metab (1976) 1.04
Ca2+ release triggered by nicotinate adenine dinucleotide phosphate in intact sea urchin eggs. Biochem J (1995) 1.03
Transport of citrate across renal brush border membrane: effects of dietary acid and alkali loading. Am J Physiol (1985) 1.02
Effects of demethylchlortetracycline on cellular action of antidiuretic hormone in vitro. Kidney Int (1974) 1.02
Effect of renal medullary solutes on vasopressin-sensitive adenyl cyclase. Am J Physiol (1972) 1.00
Role of cyclic AMP in the action of neurohypophyseal hormones on kidney. Adv Cyclic Nucleotide Res (1972) 1.00
Diazontized (125I) diiodosulafanilic acid as a label for cell surface membranes. Studies on erythrocytes. Biochim Biophys Acta (1979) 0.98
Inhibition of human renal epithelial Na+/Pi cotransport by phosphonoformic acid. Biochem Biophys Res Commun (1986) 0.98
Influence of parathyroid hormone on glomerular ultrafiltration in the rat. Am J Physiol (1978) 0.98
Role of cAMP-phosphodiesterase isozymes in pathogenesis of murine nephrogenic diabetes insipidus. Am J Physiol (1991) 0.97
Parathyroid hormone receptors of renal cortex: specific binding of biologically active, 125I-labeled hormone and relationship to adenylate cyclase activation. Proc Natl Acad Sci U S A (1974) 0.97
ANP inhibits Na(+)-H+ antiport in proximal tubular brush border membrane: role of dopamine. Kidney Int (1990) 0.97
Mechanism of glucocorticoid effect on renal transport of phosphate. Am J Physiol (1982) 0.96
Cyclic AMP in action of antidiuretic hormone: effects of exogenous cyclic AMP and its new analogue. Am J Physiol (1977) 0.96
ADP-Ribosyl cyclase in rat vascular smooth muscle cells: properties and regulation. Circ Res (2000) 0.96
Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway. Kidney Int (1997) 0.95
Enzymes of cyclic 3',5'-nucleotide metabolism in human renal cortex and renal adenocarcinoma. Kidney Int (1977) 0.95
Dynamics of renal histamine in normal rat kidney and in nephrosis induced by aminonucleoside of puromycin. J Clin Invest (1982) 0.94
Action of serotonin (5-hydroxytryptamine) on cyclic nucleotides in glomeruli of rat renal cortex. Kidney Int (1979) 0.94
Cyclic 3',5'-nucleotide diesterases in dynamics of cAMP and cGMP in rat collecting duct cells. Am J Physiol (1992) 0.94
Cyclic nucleotides in the cellular action of neurohypophyseal hormones. Fed Proc (1977) 0.93
Effects of colchicine and vinblastine on the cellular action of vasopressin in mammalian kidney. A possible role of microtubules. J Clin Invest (1974) 0.93
Synthesis of NAADP and cADPR in mitochondria. Arch Biochem Biophys (1999) 0.92
Interaction of lithium with vasopressin-sensitive cyclic AMP system of human renal medulla. Endocrinology (1974) 0.92
Effect of colchicine on urinary phosphate and regulation by parathyroid hormone. Am J Physiol (1976) 0.92
Renal adaptation to a low phosphate diet in rats. J Clin Invest (1979) 0.92
Phosphate transport across renal cortical brush border membrane vesicles from rats stabilized on a normal, high or low phosphate diet. Life Sci (1979) 0.91
Cellular action of antidiuretic hormone in nephrogenic diabetes insipidus. Mayo Clin Proc (1974) 0.91
Palmitoyl-CoA potentiates the Ca2+ release elicited by cyclic ADP-ribose. Am J Physiol (1996) 0.91
Suppressive effects of fish oil on mesangial cell proliferation in vitro and in vivo. Kidney Int (2000) 0.91
Cyclic ADP-ribose metabolism in rat kidney: high capacity for synthesis in glomeruli. Kidney Int (1997) 0.90
Decreased expression of adenosine kinase in streptozotocin-induced diabetes mellitus rats. Arch Biochem Biophys (2000) 0.90
Nephron distribution of total low Km cyclic AMP phosphodiesterase in mouse, rat and rabbit kidney. Tohoku J Exp Med (2001) 0.89
Protein kinase activity in isolated tubules of rat renal medulla. Am J Physiol (1980) 0.89
Lithium-induced polyuria: effect of lithium on adenylate cyclase and adenosine 3',5'-monophosphate phosphodiesterase in medullary ascending limb of Henle's loop and in medullary collecting tubules. Endocrinology (1980) 0.89
Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells. J Clin Invest (1995) 0.89
Nicotinamide restores phosphaturic effect of PTH and calcitonin in phosphate deprivation. Am J Physiol (1982) 0.89
Action of adenosine on cyclic 3',5'-nucleotides in glomeruli. Am J Physiol (1983) 0.88
Localization of mRNAs coding for isozymes of plasma membrane Ca(2+)-ATPase pump in rat kidney. Am J Physiol (1992) 0.88
Cellular action of vasopressin in medullary tubules of mice with hereditary nephrogenic diabetes insipidus. J Clin Invest (1980) 0.88
Interactions of [14C]phosphonoformic acid with renal cortical brush-border membranes. Relationship to the Na+-phosphate co-transporter. J Biol Chem (1987) 0.88
Interaction of forskolin with vasopressin-sensitive cyclic AMP system in renal medullary tubules. J Cyclic Nucleotide Protein Phosphor Res (1985) 0.88
Dual action of phosphonoformic acid on Na(+)-phosphate cotransport in opossum kidney cells. Am J Physiol (1992) 0.88
Autocrine/paracrine regulation of renal Na(+)-phosphate cotransport by dopamine. Am J Physiol (1993) 0.87
Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway. Biochem Biophys Res Commun (1995) 0.87
Mechanism of phosphaturia elicited by administration of phosphonoformate in vivo. Am J Physiol (1988) 0.87
Differential effect of pH upon cyclic-ADP-ribose and nicotinate-adenine dinucleotide phosphate-induced Ca2+ release systems. Biochem J (1998) 0.87
Effects of calcium on the vasopressin-sensitive cAMP metabolism in medullary tubules. Am J Physiol (1985) 0.87
Cyclic AMP-dependent reversible phosphorylation of renal medullary plasma membrane protein. Endocrinology (1972) 0.87
Nicotinamide adenine dinucleotide and renal response to parathyroid hormone. Endocrinology (1981) 0.87
ADH-sensitive cAMP system in papillary collecting duct: effect of osmolality and PGE2. Am J Physiol (1981) 0.87
Phosphorus excretion in tumoral calcinosis: response to parathyroid hormone and acetazolamide. J Clin Endocrinol Metab (1980) 0.87
Interrelationships between histamine, prostaglandins, and cyclic AMP in gastric secretion: a hypothesis. Gastroenterology (1977) 0.87
Phosphate transport in brush border membranes from uremic rats. Response to phosphonoformic acid. J Am Soc Nephrol (1992) 0.87
Measurements of cyclic AMP and cyclic GMP phosphodiesterase activity in isolated tubular segments. Kidney Int (1980) 0.86
Formation of reactive oxygen metabolites in glomeruli is suppressed by inhibition of cAMP phosphodiesterase isozyme type IV. Kidney Int (1994) 0.85
Nicotinic acid adenine dinucleotide phosphate: a new Ca2+ releasing agent in kidney. J Am Soc Nephrol (2001) 0.85
Specific modulation of cyclic ADP-ribose-induced Ca2+ release by polyamines. Am J Physiol (1995) 0.85
Administration of atrial natriuretic factor inhibits sodium-coupled transport in proximal tubules. J Clin Invest (1985) 0.85
Potential role of cyclic nucleotides in glomerular pathophysiology. Adv Cyclic Nucleotide Res (1980) 0.85
Activities of lysosomal enzymes in isolated glomeruli. Alterations in experimental nephrosis. Lab Invest (1981) 0.85
Quantitation of the Na(+)-Pi cotransporter in renal cortical brush border membranes. [14C]phosphonoformic acid as a useful probe to determine the density and its change in response to parathyroid hormone. J Biol Chem (1991) 0.85
Effect of potassium depletion on the vasopressin-sensitive cyclic AMP system in rat outer medullary tubules. J Lab Clin Med (1982) 0.85
Mechanism of dopamine inhibition of renal phosphate transport. J Am Soc Nephrol (1992) 0.84
Chlorpropamide action on renal concentrating mechanism in rats with hypothalamic diabetes insipidus. J Clin Invest (1983) 0.84
Mechanism of resistance to the phosphaturic effect of the parathyroid hormone in the hamster. J Clin Invest (1977) 0.84
Compartmentalization of cAMP signaling in mesangial cells by phosphodiesterase isozymes PDE3 and PDE4. Regulation of superoxidation and mitogenesis. J Biol Chem (1997) 0.84
Phosphate transport by brushborder membranes from superficial and juxtamedullary cortex. Kidney Int (1985) 0.84
Immunohistochemical localization of 3':5'-cyclic AMP and 3':5'-cyclic GMP in rat renal cortex: effect of parathyroid hormone. Proc Natl Acad Sci U S A (1977) 0.84
Vasopressin-prostaglandin interactions in isolated tubules from rat outer medulla. J Lab Clin Med (1980) 0.84
cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells. Am J Physiol Renal Physiol (2001) 0.84
Renal brush border membrane adaptation to phosphorus deprivation: effects of fasting versus low-phosphorus diet. Kidney Int (1980) 0.84
Effect of increased dietary phosphate intake on dopamine excretion in the presence and absence of the renal nerves. Miner Electrolyte Metab (1994) 0.83
Dopamine enhances the phosphaturic response to parathyroid hormone in phosphate-deprived rats. J Am Soc Nephrol (1992) 0.83
Modulatory effect of thyroid function on enzymes of the vasopressin-sensitive adenosine 3',5'-monophosphate system in renal medulla. Endocrinology (1978) 0.83
Suppression of mesangial proliferative glomerulonephritis development in rats by inhibitors of cAMP phosphodiesterase isozymes types III and IV. J Clin Invest (1996) 0.83
Cyclic nucleotide phosphodiesterases in glomeruli of rat renal cortex. Kidney Int (1978) 0.83
Role of cyclic AMP in the action of antidiuretic hormone on kidney. Life Sci (1973) 0.83
ATP and cAMP system in the in vitro response of microdissected cortical tubules to PTH. Am J Physiol (1985) 0.82