Published in J Clin Invest on August 01, 1986
Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis. J Pathol (2003) 1.71
Relationship of bacterial growth phase to killing of Listeria monocytogenes by oxidative agents generated by neutrophils and enzyme systems. Infect Immun (1987) 1.44
Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants. Am J Pathol (2001) 1.26
Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation. J Clin Invest (1991) 1.20
Possible role of bacterial siderophores in inflammation. Iron bound to the Pseudomonas siderophore pyochelin can function as a hydroxyl radical catalyst. J Clin Invest (1990) 1.14
Oxidative inactivation of myeloperoxidase released from human neutrophils. Biochem J (1987) 1.09
Bacterial iron enhances oxygen radical-mediated killing of Staphylococcus aureus by phagocytes. Infect Immun (1990) 0.93
The implications of oxidative stress and antioxidant therapies in Inflammatory Bowel Disease: Clinical aspects and animal models. Saudi J Gastroenterol (2016) 0.88
Mononuclear phagocytes have the potential for sustained hydroxyl radical production. Use of spin-trapping techniques to investigate mononuclear phagocyte free radical production. J Exp Med (1988) 0.87
The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin. Biochem J (1988) 0.84
Oxygen radical generation by polymorphonuclear leucocytes of beige mice. Clin Exp Immunol (1987) 0.79
Hydrogen peroxide release and hydroxyl radical formation in mixtures containing mineral fibres and human neutrophils. Br J Ind Med (1992) 0.76
Tissue injury in neutrophilic inflammation. Inflamm Res (1998) 0.75
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl (1968) 60.35
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J Clin Invest (1973) 17.56
Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J (1984) 13.20
Active oxygen species and the functions of phagocytic leukocytes. Annu Rev Biochem (1980) 5.86
Purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes. Infect Immun (1984) 5.30
Studies on the chlorinating activity of myeloperoxidase. J Biol Chem (1976) 4.38
Resolution of granules from rabbit heterophil leukocytes into distinct populations by zonal sedimentation. J Cell Biol (1969) 4.36
Formation of thiobarbituric-acid-reactive substance from deoxyribose in the presence of iron salts: the role of superoxide and hydroxyl radicals. FEBS Lett (1981) 3.92
Chlorination of taurine by human neutrophils. Evidence for hypochlorous acid generation. J Clin Invest (1982) 3.33
Oxidants from phagocytes: agents of defense and destruction. Blood (1984) 3.20
Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system. J Clin Invest (1981) 2.66
Human granulocyte generation of hydroxyl radical. J Exp Med (1978) 2.54
Generation of hydroxyl radical by enzymes, chemicals, and human phagocytes in vitro. Detection with the anti-inflammatory agent, dimethyl sulfoxide. J Clin Invest (1979) 2.40
Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals. Biochem J (1979) 2.26
Hydrogen peroxide kills Staphylococcus aureus by reacting with staphylococcal iron to form hydroxyl radical. J Biol Chem (1981) 2.16
Evidence for hydroxyl radical production by human neutrophils. J Clin Invest (1977) 2.15
Inhibition of lipid peroxidation by the iron-binding protein lactoferrin. Biochem J (1981) 1.85
The production of hydroxyl and superoxide radicals by stimulated human neutrophils- measurements by EPR spectroscopy. FEBS Lett (1979) 1.72
Isolation and properties of human neutrophil myeloperoxidase. Biochemistry (1981) 1.71
Ethylene formation by polymorphonuclear leukocytes. Role of myeloperoxidase. J Exp Med (1978) 1.64
Hydroxyl radical generation by polymorphonuclear leukocytes measured by electron spin resonance spectroscopy. J Clin Invest (1979) 1.56
Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride. Biochem J (1985) 1.51
Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent. Biochem J (1983) 1.47
A kinetic analysis of the interaction of human myeloperoxidase with hydrogen peroxide, chloride ions, and protons. J Biol Chem (1982) 1.09
Enhanced production of hydroxyl radicals by the xanthine-xanthine oxidase reaction in the presence of lactoferrin. Biochim Biophys Acta (1982) 1.09
Ethylene from 2-keto-4-thiomethyl butyric acid: the Haber-Weiss reaction. Arch Biochem Biophys (1980) 1.06
The effect of pH on the conversion of superoxide to hydroxyl free radicals. Arch Biochem Biophys (1984) 1.02
Reactions of oxygen radical species with methional: a pulse radiolysis study. Biochem Biophys Res Commun (1976) 1.01
The generation of hydroxyl radicals following superoxide production by neutrophil NADPH oxidase. FEBS Lett (1982) 0.93
Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction. Arch Biochem Biophys (1986) 0.86
Efficiency of chelated iron compounds as catalysts for the Haber-Weiss reaction. J Free Radic Biol Med (1985) 0.83
How do phagocytic cells kill bacteria? Med Biol (1984) 0.81
Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood (1998) 5.02
The estimation of red cell superoxide dismutase activity. J Lab Clin Med (1975) 2.75
Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals. Biochem J (1979) 2.26
Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of the oxidant to hypochlorite. Biochim Biophys Acta (1985) 2.15
Protein carbonyl measurement by a sensitive ELISA method. Free Radic Biol Med (1997) 2.14
Involvement of superoxide and myeloperoxidase in oxygen-dependent killing of Staphylococcus aureus by neutrophils. Infect Immun (1996) 1.83
The ability of scavengers to distinguish OH. production in the iron-catalyzed Haber-Weiss reaction: comparison of four assays for OH. Free Radic Biol Med (1987) 1.73
A microtiter plate assay for superoxide dismutase using a water-soluble tetrazolium salt (WST-1). Clin Chim Acta (2000) 1.73
Thiocyanate and chloride as competing substrates for myeloperoxidase. Biochem J (1997) 1.70
Reactions involving superoxide and normal and unstable haemoglobins. Biochem J (1976) 1.66
Oxidative reactions of hemoglobin. Methods Enzymol (1990) 1.55
Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride. Biochem J (1985) 1.51
Kinetics of the reactions of hypochlorous acid and amino acid chloramines with thiols, methionine, and ascorbate. Free Radic Biol Med (2001) 1.50
Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent. Biochem J (1983) 1.47
Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils. J Biol Chem (1995) 1.45
Oxidation of parenteral lipid emulsion by ambient and phototherapy lights: potential toxicity of routine parenteral feeding. J Pediatr (1995) 1.45
Assays for the chlorination activity of myeloperoxidase. Methods Enzymol (1994) 1.45
Activated oxygen and haemolysis. Br J Haematol (1975) 1.41
Studies of hemoglobin denaturation and Heinz body formation in the unstable hemoglobins. J Clin Invest (1974) 1.39
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl. Arch Biochem Biophys (1991) 1.33
Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide. Biochem J (1997) 1.33
Hydroxyl radical production in body fluids. Roles of metal ions, ascorbate and superoxide. Biochem J (1981) 1.32
Inhibition of myeloperoxidase by benzoic acid hydrazides. Biochem J (1995) 1.26
A single assay for measuring the rates of phagocytosis and bacterial killing by neutrophils. J Leukoc Biol (1994) 1.24
Oxidation of human haemoglobin by copper. Mechanism and suggested role of the thiol group of residue beta-93. Biochem J (1977) 1.22
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid. Biochem J (1988) 1.22
Oxidation of intracellular glutathione after exposure of human red blood cells to hypochlorous acid. Biochem J (1995) 1.18
Living with a killer: the effects of hypochlorous acid on mammalian cells. IUBMB Life (2001) 1.17
Mechanism of inhibition of myeloperoxidase by anti-inflammatory drugs. Biochem Pharmacol (1991) 1.16
Cytochrome c reduction by semiquinone radicals can be indirectly inhibited by superoxide dismutase. Arch Biochem Biophys (1981) 1.16
Methods for quantifying phagocytosis and bacterial killing by human neutrophils. J Immunol Methods (1999) 1.14
Free-radical production and oxidative reactions of hemoglobin. Environ Health Perspect (1985) 1.12
The rate of reaction of superoxide radical ion with oxyhaemoglobin and methaemoglobin. Biochem J (1976) 1.11
On the participation of higher oxidation states of iron and copper in Fenton reactions. Free Radic Biol Med (1989) 1.10
Production of hydroxyl radicals from paraquat radicals and H2O2. FEBS Lett (1981) 1.07
Human neutrophil collagenase cleaves alpha 1-antitrypsin. Biochem J (1990) 1.07
Nitrite as a substrate and inhibitor of myeloperoxidase. Implications for nitration and hypochlorous acid production at sites of inflammation. J Biol Chem (2000) 1.06
Mechanism of oxyhaemoglobin breakdown on reaction with acetylphenylhydrazine. Biochem J (1978) 1.06
Degradation of glomerular basement membrane by human neutrophils in vitro. Biochim Biophys Acta (1984) 1.06
Hydroxyl radical production from hydrogen peroxide and enzymatically generated paraquat radicals: catalytic requirements and oxygen dependence. Arch Biochem Biophys (1984) 1.05
Radical driven Fenton reactions--evidence from paraquat radical studies for production of tetravalent iron in the presence and absence of ethylenediaminetetraacetic acid. Arch Biochem Biophys (1987) 1.03
The effect of oxidants on neutrophil-mediated degradation of glomerular basement membrane collagen. Biochim Biophys Acta (1986) 1.03
Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode. Biochem J (1989) 1.03
Superoxide is an antagonist of antiinflammatory drugs that inhibit hypochlorous acid production by myeloperoxidase. Biochem Pharmacol (1993) 1.02
Modification of neutrophil oxidant production with diphenyleneiodonium and its effect on bacterial killing. Free Radic Biol Med (1995) 1.02
Superoxide dismutase as an inhibitor of reactions of semiquinone radicals. FEBS Lett (1978) 1.02
Hypochlorous acid stimulation of the mitogen-activated protein kinase pathway enhances cell survival. Arch Biochem Biophys (2001) 1.01
Inhibition of neutrophil degranulation and superoxide production by sulfasalazine. Comparison with 5-aminosalicylic acid, sulfapyridine and olsalazine. Biochem Pharmacol (1987) 1.01
A genetically engineered mutant of alpha 1-antitrypsin protects connective tissue from neutrophil damage and may be useful in lung disease. Lancet (1984) 0.98
Bacterial killing by neutrophils in hypertonic environments. J Infect Dis (1994) 0.98
Peroxynitrite and myeloperoxidase leave the same footprint in protein nitration. Redox Rep (1998) 0.98
Neutrophils adherent to a nonphagocytosable surface (glomerular basement membrane) produce oxidants only at the site of attachment. Blood (1985) 0.98
Low density lipoprotein peptide metabolism in nephrotic syndrome: a comparison with patterns observed in other syndromes characterised by hyperlipoproteinaemia. Australas Ann Med (1970) 0.98
The mechanism of myeloperoxidase-dependent chlorination of monochlorodimedon. Biochim Biophys Acta (1988) 0.98
Assays using horseradish peroxidase and phenolic substrates require superoxide dismutase for accurate determination of hydrogen peroxide production by neutrophils. Free Radic Biol Med (1994) 0.98
Loss of GSH and thiol enzymes in endothelial cells exposed to sublethal concentrations of hypochlorous acid. Am J Physiol (1999) 0.96
Elevated protein carbonyls and lipid peroxidation products correlating with myeloperoxidase in tracheal aspirates from premature infants. Pediatr Res (2000) 0.95
Early ascorbic acid depletion is related to the severity of acute pancreatitis. Br J Surg (1999) 0.95
Generation of superoxide and tyrosine peroxide as a result of tyrosyl radical scavenging by glutathione. Arch Biochem Biophys (1995) 0.94
Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione disulfide. J Biol Chem (2001) 0.94
Vitamin C is reduced in human milk after storage. Acta Paediatr (2001) 0.93
The correlation of elevated levels of an index of lipid peroxidation (MDA-TBA) with adverse outcome in the very low birthweight infant. Acta Paediatr (1996) 0.93
A kinetic analysis of the catalase activity of myeloperoxidase. Biochemistry (2001) 0.92
Superoxide-dependent hydroxylation by myeloperoxidase. J Biol Chem (1994) 0.92
Vitamin C supplementation in very preterm infants: a randomised controlled trial. Arch Dis Child Fetal Neonatal Ed (2005) 0.91
Chlorination of cholesterol in cell membranes by hypochlorous acid. Arch Biochem Biophys (1996) 0.91
Membrane changes associated with lysis of red blood cells by hypochlorous acid. Free Radic Biol Med (1994) 0.91
Doxorubicin-dependent lipid peroxidation at low partial pressures of O2. J Free Radic Biol Med (1985) 0.90
Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid. Biochem J (1997) 0.90
Hypochlorous acid-mediated modification of cholesterol and phospholipid: analysis of reaction products by gas chromatography-mass spectrometry. J Lipid Res (1993) 0.90
Gelatinase contributes to the degradation of glomerular basement membrane collagen by human neutrophils. Coll Relat Res (1988) 0.89
Low-density lipoprotein accumulation in actively growing xanthomas. J Atheroscler Res (1967) 0.89
Superoxide enhances hypochlorous acid production by stimulated human neutrophils. Biochim Biophys Acta (1990) 0.89
Myeloperoxidase-dependent oxidative inactivation of neutrophil neutral proteinases and microbicidal enzymes. Biochem J (1987) 0.89
A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide. Biochim Biophys Acta (1988) 0.89
Modification of red cell membrane lipids by hypochlorous acid and haemolysis by preformed lipid chlorohydrins. Redox Rep (1998) 0.89
Different effects of hypochlorous acid on human neutrophil metalloproteinases: activation of collagenase and inactivation of collagenase and gelatinase. Arch Biochem Biophys (1992) 0.88
Cleavage and inactivation of alpha 1-antitrypsin by metalloproteinases released from neutrophils. J Clin Invest (1988) 0.88
Limiting light-induced lipid peroxidation and vitamin loss in infant parenteral nutrition by adding multivitamin preparations to Intralipid. Acta Paediatr (2001) 0.87
The reaction of menadione with haemoglobin. Mechanism and effect of superoxide dismutase. Biochem J (1979) 0.87
Iron and xanthine oxidase catalyze formation of an oxidant species distinguishable from OH.: comparison with the Haber-Weiss reaction. Arch Biochem Biophys (1986) 0.86
The attachment of Heinz bodies to the red cell membrane. Br J Haematol (1973) 0.86
Deoxyribose breakdown by the adriamycin semiquinone and H2O2: evidence for hydroxyl radical participation. FEBS Lett (1982) 0.85
Reactions of Adriamycin with haemoglobin. Superoxide dismutase indirectly inhibits reactions of the Adriamycin semiquinone. Biochem J (1982) 0.85
Selenium and glutathione peroxidase levels in premature infants in a low selenium community (Christchurch, New Zealand). Pediatr Res (1992) 0.84
Proteinase-antiproteinase balance in tracheal aspirates from neonates. Eur Respir J (1994) 0.84
Inhibition by nonsteroidal anti-inflammatory drugs of superoxide production and granule enzyme release by polymorphonuclear leukocytes stimulated with immune complexes or formyl-methionyl-leucyl-phenylalanine. Biochem Pharmacol (1987) 0.84
The superoxide-dependent transfer of iron from ferritin to transferrin and lactoferrin. Biochem J (1988) 0.84
6-Hydroxydopamine releases iron from ferritin and promotes ferritin-dependent lipid peroxidation. Biochem Pharmacol (1989) 0.84
Reduced glutathione in combination with superoxide dismutase as an important biological antioxidant defence mechanism. Biochem Pharmacol (1989) 0.83
Chelated iron-catalyzed OH. formation from paraquat radicals and H2O2: mechanism of formate oxidation. Arch Biochem Biophys (1984) 0.83
Oxidative interactions between haemoglobin and membrane lipid. A liposome model. Biochem J (1984) 0.83
The relationship of selenium status to respiratory outcome in the very low birth weight infant. Pediatrics (1995) 0.83
Plasma vitamin A levels in the very low birthweight infant--relationship to respiratory outcome. Early Hum Dev (1998) 0.83
Activation of human neutrophil gelatinase by endogenous serine proteinases. Biochem J (1988) 0.83
Contributions of superoxide, hydrogen peroxide, and transition metal ions to auto-oxidation of the favism-inducing pyrimidine aglycone, divicine, and its reactions with haemoglobin. Biochem Pharmacol (1986) 0.82
The hydrolysis product of ICRF-187 promotes iron-catalysed hydroxyl radical production via the Fenton reaction. Biochem Pharmacol (1993) 0.82
The uptake of plasma fatty acids into human red cells and its relationship to cell age. Biochim Biophys Acta (1970) 0.82
Peroxidase-mediated bromination of unsaturated fatty acids to form bromohydrins. Arch Biochem Biophys (1996) 0.82
Characterization of Heinz bodies in unstable haemoglobin haemolytic anaemia. Nature (1972) 0.81