Published in Mol Cell Biol on November 01, 1985
Elements upstream of the AAUAAA within the human immunodeficiency virus polyadenylation signal are required for efficient polyadenylation in vitro. Mol Cell Biol (1992) 1.93
Definition of the upstream efficiency element of the simian virus 40 late polyadenylation signal by using in vitro analyses. Mol Cell Biol (1992) 1.72
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Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removal. Mol Cell Biol (1999) 1.48
Competition between splicing and polyadenylation reactions determines which adenovirus region E3 mRNAs are synthesized. Mol Cell Biol (1988) 1.20
Two distant upstream regions containing cis-acting signals regulating splicing facilitate 3'-end processing of avian sarcoma virus RNA. J Virol (1992) 1.17
Identification of a novel sequence that governs both polyadenylation and alternative splicing in region E3 of adenovirus. Nucleic Acids Res (1987) 1.11
Genetic analysis of mRNA synthesis in adenovirus region E3 at different stages of productive infection by RNA-processing mutants. J Virol (1986) 1.10
A small deletion distant from a splice or polyadenylation site dramatically alters pre-mRNA processing in region E3 of adenovirus. J Virol (1987) 1.06
Functionally significant secondary structure of the simian virus 40 late polyadenylation signal. Mol Cell Biol (2000) 1.05
Requirement of A-A-U-A-A-A and adjacent downstream sequences for SV40 early polyadenylation. Nucleic Acids Res (1986) 1.04
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Map of cis-acting sequences that determine alternative pre-mRNA processing in the E3 complex transcription unit of adenovirus. J Virol (1992) 0.87
Deletions in the SV40 late polyadenylation region downstream of the AATAAA mediate similar effects on expression in various mammalian cell lines. Nucleic Acids Res (1988) 0.86
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A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology (1973) 127.36
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The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs. Cell (1981) 12.26
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Requirement of a downstream sequence for generation of a poly(A) addition site. Cell (1984) 4.87
Formation of the 3' end of histone mRNA by post-transcriptional processing. Nature (1984) 4.75
Alpha-thalassaemia caused by a polyadenylation signal mutation. Nature (1984) 4.41
Nucleotide sequence of the EcoRI D fragment of adenovirus 2 genome. Nucleic Acids Res (1980) 4.34
A sequence downstream of AAUAAA is required for rabbit beta-globin mRNA 3'-end formation. Nature (1985) 4.26
Analysis of processing and polyadenylation signals of the hepatitis B virus surface antigen gene by using simian virus 40-hepatitis B virus chimeric plasmids. Mol Cell Biol (1983) 3.63
Site-specific polyadenylation in a cell-free reaction. Cell (1984) 3.59
The cDNA sequences of the sea urchin U7 small nuclear RNA suggest specific contacts between histone mRNA precursor and U7 RNA during RNA processing. EMBO J (1984) 3.36
Biochemical complementation with RNA in the Xenopus oocyte: a small RNA is required for the generation of 3' histone mRNA termini. Cell (1983) 3.36
The terminal RNA stem-loop structure and 80 bp of spacer DNA are required for the formation of 3' termini of sea urchin H2A mRNA. Cell (1983) 3.19
Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site. Mol Cell Biol (1984) 3.09
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Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry (1981) 2.67
Requirement for the 3' flanking region of the bovine growth hormone gene for accurate polyadenylylation. Proc Natl Acad Sci U S A (1984) 2.58
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Physical mapping of a large-plaque mutation of adenovirus type 2. J Virol (1979) 2.50
Termination of transcription in the mouse alpha-amylase gene Amy-2a occurs at multiple sites downstream of the polyadenylation site. Cell (1984) 2.44
Structure of two adenovirus type 12 transforming polypeptides and their evolutionary implications. Nature (1980) 2.38
The conserved CAAGAAAGA spacer sequence is an essential element for the formation of 3' termini of the sea urchin H3 histone mRNA by RNA processing. EMBO J (1985) 2.34
Transcription termination occurs within a 1000 base pair region downstream from the poly(A) site of the mouse beta-globin (major) gene. Nucleic Acids Res (1984) 2.24
DNA sequence of the early E3 transcription unit of adenovirus 5. Virology (1985) 2.17
Human adenoviruses: growth, purification, and transfection assay. Methods Enzymol (1979) 2.06
The major late adenovirus type-2 transcription unit: termination is downstream from the last poly(A) site. J Mol Biol (1979) 2.04
RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro. Mol Cell Biol (1985) 1.81
Thalassemia due to a mutation in the cleavage-polyadenylation signal of the human beta-globin gene. EMBO J (1985) 1.79
Cloning and structure of the human immune interferon-gamma chromosomal gene. EMBO J (1982) 1.71
The 3' end of drosophila histone H3 mRNA is produced by a processing activity in vitro. Cell (1984) 1.69
Multiple 3' ends of the chicken pro alpha 2(I) collagen gene. Nucleic Acids Res (1983) 1.61
Analysis in Cos-1 cells of processing and polyadenylation signals by using derivatives of the herpes simplex virus type 1 thymidine kinase gene. Mol Cell Biol (1983) 1.58
Transcription of the mouse dihydrofolate reductase gene proceeds unabated through seven polyadenylation sites and terminates near a region of repeated DNA. Mol Cell Biol (1984) 1.55
Termination of the ovalbumin gene transcription. EMBO J (1984) 1.53
Transcription unit of the rabbit beta 1 globin gene. Mol Cell Biol (1985) 1.40
Polyadenylic acid addition sites in the adenovirus type 2 major late transcription unit. J Virol (1983) 1.22
Mapping the 5' ends, 3' ends, and splice sites of mRNAs from the early E3 transcription unit of adenovirus 5. Virology (1985) 1.18
Rna synthesis in isolated nuclei processing of adenovirus serotype 2 late messenger rna precursors. J Mol Biol (1982) 1.17
Polyadenylation of the Xenopus beta 1 globin mRNA at a downstream minor site in the absence of the major site and utilization of an AAUACA polyadenylation signal. EMBO J (1985) 1.16
Structure of three spliced mRNAs from region E3 of adenovirus type 2. Gene (1983) 1.13
Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart. Nucleic Acids Res (1983) 1.06
Poly(A) sites of adenovirus serotype 2 transcription units. J Mol Biol (1982) 1.04
Genome expression and mRNA maturation at late stages of productive adenovirus type 2 infection. J Virol (1976) 1.03
The sequence of 3'-termini of mRNAs from early region III of adenovirus 2. Gene (1982) 0.99
Mapping of the 3' terminus of the large late ad-2 transcript by electron microscopy. Virology (1980) 0.93
DNA sequences affecting specific initiation of transcription in vitro from the EIII promoter of adenovirus 2. Proc Natl Acad Sci U S A (1982) 6.57
The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha. Mol Cell Biol (1992) 4.17
Immunological identification of two adenovirus 2-induced early proteins possibly involved in cell transformation. Nature (1976) 3.01
A short sequence in the COOH-terminus makes an adenovirus membrane glycoprotein a resident of the endoplasmic reticulum. Cell (1987) 2.88
Role of early region 3 (E3) in pathogenesis of adenovirus disease. Proc Natl Acad Sci U S A (1989) 2.74
The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells. J Virol (1996) 2.25
A 14,700 MW protein from the E3 region of adenovirus inhibits cytolysis by tumor necrosis factor. Cell (1988) 2.20
DNA sequence of the early E3 transcription unit of adenovirus 5. Virology (1985) 2.17
Thirty-one human adenovirus serotypes (Ad1-Ad31) form five groups (A-E) based upon DNA genome homologies. Virology (1979) 2.14
Human adenoviruses: growth, purification, and transfection assay. Methods Enzymol (1979) 2.06
Forced degradation of Fas inhibits apoptosis in adenovirus-infected cells. Nature (1998) 1.87
Identification of families of overlapping polypeptides coded by early "transforming" gene region 1 of human adenovirus type 2. Virology (1979) 1.83
The E1B 19,000-molecular-weight protein of group C adenoviruses prevents tumor necrosis factor cytolysis of human cells but not of mouse cells. J Virol (1991) 1.65
Detection of adenovirus type 2-induced early polypeptides using cycloheximide pretreatment to enhance viral protein synthesis. J Virol (1976) 1.64
Epidermal growth factor receptor is down-regulated by a 10,400 MW protein encoded by the E3 region of adenovirus. Cell (1989) 1.63
Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor. J Immunol (1989) 1.59
The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus function together to protect many but not all mouse cell lines against lysis by tumor necrosis factor. J Virol (1991) 1.58
Identification and peptide mapping of human adenovirus type 2-induced early polypeptides isolated by two-dimensional gel electrophoresis and immunoprecipitation. J Biol Chem (1980) 1.48
The E3-11.6-kDa adenovirus death protein (ADP) is required for efficient cell death: characterization of cells infected with adp mutants. Virology (1996) 1.48
Evidence that AGUAUAUGA and CCAAGAUGA initiate translation in the same mRNA region E3 of adenovirus. Virology (1986) 1.47
cyt gene of adenoviruses 2 and 5 is an oncogene for transforming function in early region E1B and encodes the E1B 19,000-molecular-weight polypeptide. J Virol (1984) 1.45
Mapping a new gene that encodes an 11,600-molecular-weight protein in the E3 transcription unit of adenovirus 2. J Virol (1984) 1.43
Tumor-specific, replication-competent adenovirus vectors overexpressing the adenovirus death protein. J Virol (2000) 1.43
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Mouse anti-adenovirus cytotoxic T lymphocytes. Inhibition of lysis by E3 gp19K but not E3 14.7K. J Immunol (1989) 1.38
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Identification and gene mapping of a 14,700-molecular-weight protein encoded by region E3 of group C adenoviruses. J Virol (1988) 1.31
Specificity of the mouse cytotoxic T lymphocyte response to adenovirus 5. E1A is immunodominant in H-2b, but not in H-2d or H-2k mice. J Immunol (1991) 1.29
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The 19-kDa glycoprotein coded by region E3 of adenovirus. Purification, characterization, and structural analysis. J Biol Chem (1985) 1.28
Immunogenicity and efficacy testing in chimpanzees of an oral hepatitis B vaccine based on live recombinant adenovirus. Proc Natl Acad Sci U S A (1989) 1.27
The 10,400- and 14,500-dalton proteins encoded by region E3 of adenovirus form a complex and function together to down-regulate the epidermal growth factor receptor. J Virol (1991) 1.26
The amino-terminal portion of CD1 of the adenovirus E1A proteins is required to induce susceptibility to tumor necrosis factor cytolysis in adenovirus-infected mouse cells. J Virol (1991) 1.25
Inhibition of TRAIL-induced apoptosis and forced internalization of TRAIL receptor 1 by adenovirus proteins. J Virol (2001) 1.24
Adenovirus E3 14.7K protein functions in the absence of other adenovirus proteins to protect transfected cells from tumor necrosis factor cytolysis. J Virol (1991) 1.22
Adenovirus type 2 early polypeptides immunoprecipitated by antisera to five lines of adenovirus-transformed rat cells. J Virol (1979) 1.22
Immunofluorescence study of the adenovirus type 2 single-stranded DNA binding protein in infected and transformed cells. J Virol (1977) 1.21
Competition between splicing and polyadenylation reactions determines which adenovirus region E3 mRNAs are synthesized. Mol Cell Biol (1988) 1.20
A 10,400-molecular-weight membrane protein is coded by region E3 of adenovirus. J Virol (1990) 1.18
Mapping the 5' ends, 3' ends, and splice sites of mRNAs from the early E3 transcription unit of adenovirus 5. Virology (1985) 1.18
Adenovirus type 2 coded single-stranded DNA binding protein: in vivo phosphorylation and modification. J Virol (1977) 1.16
Adenovirus-human immunodeficiency virus (HIV) envelope recombinant vaccines elicit high-titered HIV-neutralizing antibodies in the dog model. Proc Natl Acad Sci U S A (1992) 1.15
The role of human adenovirus early region 3 proteins (gp19K, 10.4K, 14.5K, and 14.7K) in a murine pneumonia model. J Virol (1996) 1.14
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Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival. Mol Cell Biol (2001) 1.11
Novel deletion mutants that enhance a distant upstream 5' splice in the E3 transcription unit of adenovirus 2. Nucleic Acids Res (1985) 1.11
Analysis of human tumors and human malignant cell lines for BK virus-specific DNA sequences. Proc Natl Acad Sci U S A (1978) 1.11
Identification of a novel sequence that governs both polyadenylation and alternative splicing in region E3 of adenovirus. Nucleic Acids Res (1987) 1.11
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Genetic analysis of mRNA synthesis in adenovirus region E3 at different stages of productive infection by RNA-processing mutants. J Virol (1986) 1.10
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Characterization of mutants within the gene for the adenovirus E3 14.7-kilodalton protein which prevents cytolysis by tumor necrosis factor. J Virol (1993) 1.07
A small deletion distant from a splice or polyadenylation site dramatically alters pre-mRNA processing in region E3 of adenovirus. J Virol (1987) 1.06
The 11,600-MW protein encoded by region E3 of adenovirus is expressed early but is greatly amplified at late stages of infection. J Virol (1992) 1.06
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A 6700 MW membrane protein is encoded by region E3 of adenovirus type 2. Virology (1990) 1.01
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A protein serologically and functionally related to the group C E3 14,700-kilodalton protein is found in multiple adenovirus serotypes. J Virol (1990) 0.96
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