Published in Br J Clin Pharmacol on August 01, 1986
The pharmacokinetics and angiotensin converting enzyme inhibition dynamics of cilazapril in essential hypertension. Br J Clin Pharmacol (1989) 0.94
The influence of food on the pharmacokinetics and ACE inhibition of cilazapril. Br J Clin Pharmacol (1989) 0.77
The influence of cilazapril on indices of autonomic function in normotensives and hypertensives. Br J Clin Pharmacol (1989) 0.77
Antihypertensive effects and pharmacokinetics of single and consecutive doses of cilazapril in hypertensive patients with normal or impaired renal function. Br J Clin Pharmacol (1989) 0.75
Clinical pharmacology of cilazapril. Drugs (1991) 0.75
Simultaneous radioenzymatic determination of plasma and tissue adrenaline, noradrenaline and dopamine within the femtomole range. Life Sci (1976) 5.54
Antihypertensive effect of the oral angiotensin converting-enzyme inhibitor SQ 14225 in man. N Engl J Med (1978) 5.04
A liquid chromatography-assisted assay for angiotensin-converting enzyme (peptidyl dipeptidase) in serum. Clin Chem (1979) 1.85
Pharmacodynamics of converting enzyme inhibition: the cardiovascular, endocrine and autonomic effects of MK421 (enalapril) and MK521. Br J Clin Pharmacol (1982) 1.81
Discrepancy between antihypertensive effect and angiotensin converting enzyme inhibition by captopril. Hypertension (1980) 1.81
Biological properties of the angiotensin-converting enzyme inhibitor cilazapril. J Cardiovasc Pharmacol (1985) 1.51
Evidence of parasympathetic activity of the angiotensin converting enzyme inhibitor, captopril, in normotensive man. Clin Sci (Lond) (1985) 1.49
Simplified radioimmunoassay for serum aldosterone utilizing increased antibody specificity. J Clin Endocrinol Metab (1974) 1.40
Acute and chronic effects of the converting enzyme inhibitors enalapril and lisinopril on reflex control of heart rate in normotensive man. J Hypertens (1985) 1.29
The effect of captopril on the reflex control heart rate: possible mechanisms. Br J Clin Pharmacol (1985) 1.29
Heart rate control in hypertensive patients treated by captopril. Br J Clin Pharmacol (1982) 1.10
Control of enzymatically inactive renin in man under various pathological conditions: implications for the interpretation of renin measurements in peripheral and renal venous plasma. Clin Sci Mol Med (1978) 1.07
Plasma catecholamines and cardiovascular responses during converting enzyme inhibition in normotensive and hypertensive man. Clin Exp Hypertens A (1982) 1.01
Long-term converting enzyme inhibition and sympathetic nerve function in hypertensive humans. Hypertension (1982) 0.95
Use of first-dose response or plasma renin activity to predict the long-term effect of captopril: identification of triphasic pattern of blood pressure response. J Cardiovasc Pharmacol (1980) 0.92
Age and the pharmacodynamics of angiotensin converting enzyme inhibitors enalapril and enalaprilat. Br J Clin Pharmacol (1986) 0.91
Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature (1998) 8.75
White-coat hypertension as a cause of cardiovascular dysfunction. Lancet (1996) 4.68
Epidemiology of respiratory syncytial virus infection in Washington, D.C. I. Importance of the virus in different respiratory tract disease syndromes and temporal distribution of infection. Am J Epidemiol (1973) 3.77
Do inhibitors of angiotensin-I-converting enzyme protect against risk of cancer? Lancet (1998) 3.41
Clinical pharmacology and pharmacokinetics of clonidine. Clin Pharmacol Ther (1976) 3.13
Analysis of the pressor dose response. Clin Pharmacol Ther (1982) 2.44
Effects of prostaglandins, theophylline, and cholera exotoxin upon transmucosal water and electrolyte movement in the canine jejunum. Gastroenterology (1971) 2.39
Immediate cardiovascular responses to oral prazosin--effects of concurrent beta-blockers. Clin Pharmacol Ther (1981) 2.36
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth. EMBO J (1999) 2.23
Small bowel morphology in experimental canine cholera. A light and electron microscopic study. Lab Invest (1970) 2.12
A pharmacodynamic and pharmacokinetic assessment of a new alpha-adrenoceptor antagonist, doxazosin (UK33274) in normotensive subjects. Br J Clin Pharmacol (1982) 2.06
Placebo-controlled trial of atenolol in treatment of pregnancy-associated hypertension. Lancet (1983) 2.03
Clonidine withdrawal in hypertension. Changes in blood-pressure and plasma and urinary noradrenaline. Lancet (1977) 2.01
Topographic detection of photorefractive keratectomy. Ophthalmology (1998) 1.97
Nifedipine GITS. Lancet (1993) 1.94
Coordinating and standardizing long-term care: evaluation of the west of Scotland shared-care scheme for hypertension. Br J Gen Pract (1994) 1.92
Pharmacokinetics and concentration-effect relationships of intervenous and oral clonidine. Clin Pharmacol Ther (1977) 1.91
Doxazosin, an alpha 1-adrenoceptor antagonist: pharmacokinetics and concentration-effect relationships in man. Br J Clin Pharmacol (1983) 1.89
Pharmacodynamics of converting enzyme inhibition: the cardiovascular, endocrine and autonomic effects of MK421 (enalapril) and MK521. Br J Clin Pharmacol (1982) 1.81
Effect of intravenous adrenaline on electrocardiogram, blood pressure, and serum potassium. Br Heart J (1983) 1.79
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic. Br Med J (Clin Res Ed) (1984) 1.69
Cardiovascular reflexes in Parkinsonism. Clin Sci (1971) 1.62
Idiopathic Parkinsonism treated with an extracerebral decarboxylase inhibitor in combination with levodopa. Br Med J (1971) 1.60
Brain concentration of propranolol in relation to hypotensive effect in the rabbit with observations on brain propranolol levels in man. J Pharmacol Exp Ther (1975) 1.56
The effects of cardioselective and non-selective beta-adrenoceptor blockade on the hypokalaemic and cardiovascular responses to adrenomedullary hormones in man. Clin Sci (Lond) (1983) 1.56
Aluminium toxicity during regular haemodialysis. Br Med J (1978) 1.54
Evidence of parasympathetic activity of the angiotensin converting enzyme inhibitor, captopril, in normotensive man. Clin Sci (Lond) (1985) 1.49
Verapamil pharmacokinetics and apparent hepatic and renal blood flow. Br J Clin Pharmacol (1985) 1.46
Central hypotensive effect of propranolol in the rabbit. Br J Pharmacol (1973) 1.44
Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium. Hypertension (1999) 1.44
Endothelial dysfunction as a possible link between C-reactive protein levels and cardiovascular disease. Clin Sci (Lond) (2000) 1.44
The importance of central adrenergic neurones in renal hypertension in rabbits. J Physiol (1974) 1.43
Atrophy of villi with hypertrophy and hyperplasia of Paneth cells in isolated (thiry-Vella) ileal loops in rabbits. Light-microscopic studies. Gastroenterology (1975) 1.41
Kinetic and dynamic comparison of piretanide and furosemide. Clin Pharmacol Ther (1978) 1.40
Effects of single and repeated doses of omeprazole on gastric acid and pepsin secretion in man. Gut (1984) 1.36
Clinical pharmacokinetics of amlodipine. Clin Pharmacokinet (1992) 1.33
Technical report: quantitative assessment of diaphragmatic movement--a reproducible method using ultrasound. Clin Radiol (1992) 1.30
Desmethylimipramine and the hypotensive action of clonidine in the rabbit. Br J Pharmacol (1972) 1.30
Acute and chronic effects of the converting enzyme inhibitors enalapril and lisinopril on reflex control of heart rate in normotensive man. J Hypertens (1985) 1.29
The effect of captopril on the reflex control heart rate: possible mechanisms. Br J Clin Pharmacol (1985) 1.29
Infections in 18,000 infants and children in a controlled study of respiratory tract disease. II. Variation in adenovirus infections by year and season. Am J Epidemiol (1972) 1.27
Central noradrenergic neurones and the cardiovascular actions of clonidine in the rabbit. Br J Pharmacol (1973) 1.27
Prazosin disposition in young and elderly subjects. Br J Clin Pharmacol (1981) 1.24
Plasmapheresis in the treatment of dialysis encephalopathy. Lancet (1978) 1.23
A pragmatic approach to the pressor dose-response as an index of vascular reactivity and adrenoceptor function in man. Br J Clin Pharmacol (1987) 1.22
Evidence for postjunctional vascular alpha 2-adrenoceptors in peripheral vascular regulation in man. Clin Sci (Lond) (1983) 1.22
How reproducible is bilateral forearm plethysmography? Br J Clin Pharmacol (1998) 1.21
The effect of nisoldipine on apparent liver blood flow and effective renal plasma flow. Br J Clin Pharmacol (1985) 1.20
Idiopathic parkinsonism treated with bromocriptine. Lancet (1975) 1.20
Effects of the angiotensin converting enzyme inhibitor, captopril, in essential hypertension. Br J Clin Pharmacol (1982) 1.19
Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab (1993) 1.18
Sensitivity to cerebral ischaemic insult in a rat model of stroke is determined by a single genetic locus. Nat Genet (1997) 1.18
The pressor dose-response in clinical cardiovascular pharmacology. Br J Clin Pharmacol (1987) 1.17
Effects of clonidine on biochemical indices of sympathetic function and plasma renin activity in normotensive man. Clin Sci Mol Med (1977) 1.17
Pharmacokinetic and concentration-effect relationships of clonidine in essential hypertension. Eur J Clin Pharmacol (1977) 1.16
Preliminary experience with a hospital blood pressure follow up clinic with nurse practitioner assessment and microprocessor based data retrieval. Br Med J (Clin Res Ed) (1984) 1.16
Oral pharmacokinetics of omeprazole. Eur J Clin Pharmacol (1984) 1.16
The pharmacokinetics, antihistamine and concentration-effect relationship of ebastine in healthy subjects. Br J Clin Pharmacol (1988) 1.16
Kinetic-dynamic relations and individual responses to enalapril. Hypertension (1990) 1.16
Policies for managing hypertensive patients: a survey of the opinions of British specialists. J Hum Hypertens (1990) 1.14
Prior thiazide diuretic treatment increases adrenaline-induced hypokalaemia. Lancet (1983) 1.14
Dietary sodium restriction impairs insulin sensitivity in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab (1998) 1.14
Age and the pharmacokinetics of angiotensin converting enzyme inhibitors enalapril and enalaprilat. Br J Clin Pharmacol (1986) 1.13
Atenolol disposition in young and elderly subjects. Br J Clin Pharmacol (1982) 1.13
The role of adrenal medullary catecholamines in potassium homoeostasis. Clin Sci (Lond) (1984) 1.13
[3H]yohimbine and [3H]idazoxan bind to different sites on rabbit forebrain and kidney membranes. Eur J Pharmacol (1988) 1.13
Platelet alpha-adrenoceptors--a valid model for brain or vascular adrenoceptors? Br J Clin Pharmacol (1986) 1.12
Interaction between clonidine and desipramine in man. Br Med J (1973) 1.11
Endothelial nitric oxide production and insulin sensitivity. A physiological link with implications for pathogenesis of cardiovascular disease. Circulation (1996) 1.11
Effect of age on the responsiveness of vascular alpha-adrenoceptors in man. J Cardiovasc Pharmacol (1982) 1.10
Nifedipine does not influence adrenaline induced hypokalaemia in man. Br J Clin Pharmacol (1983) 1.09
Plasma noradrenaline concentration in essential hypertension during long-term beta-adrenoceptor blockade with oxprenolol. Br J Clin Pharmacol (1980) 1.09
Acute thermoregulatory and cardiovascular effects of 6-hydroxydopamine administered centrally in rabbits and cats. Br J Pharmacol (1972) 1.09
Central and peripheral adrenergic mechanisms in the development of deoxycorticosterone-saline hypertension in rats. Circ Res (1975) 1.07
The experiences of an acute stroke unit--implications for multicentre acute stroke trials. J Neurol Neurosurg Psychiatry (1993) 1.06
The influence of naloxone on the circulatory effects of captopril. Br J Clin Pharmacol (1984) 1.06
Blood pressure in genetically hypertensive rats. Influence of the Y chromosome. Hypertension (1995) 1.05
Effects of angiotensin converting enzyme inhibitor, perindopril, on autonomic reflexes. Eur J Clin Pharmacol (1986) 1.05
Cardiovascular effects of intracerebroventricular d-, l- and dl-propranolol in the conscious rabbit. J Pharmacol Exp Ther (1974) 1.05
Plasma concentration of levodopa in Parkinsonism before and after inhibition of peripheral decarboxylase. J Neurol Sci (1972) 1.05
Nifedipine: individual responses and concentration-effect relationships. Hypertension (1988) 1.03
Concentration effect modelling with converting enzyme inhibitors in man. Br J Clin Pharmacol (1983) 1.03
Hypercholesterolaemia in treated hypertensives: a controlled trial of intensive dietary advice. J Hypertens Suppl (1989) 1.03