PubRank

P Schedl

Author PubWeight™ 163.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A position-effect assay for boundaries of higher order chromosomal domains. Cell 1991 6.04
2 Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins. Cell 1988 4.52
3 A group of scs elements function as domain boundaries in an enhancer-blocking assay. Mol Cell Biol 1992 3.76
4 Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster. Cell 1979 3.68
5 Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila. Cell 1991 3.43
6 Functional changes associated with structural alterations induced by mobilization of a P element inserted in the Sex-lethal gene of Drosophila. Genetics 1987 3.01
7 The 87A7 chromomere. Identification of novel chromatin structures flanking the heat shock locus that may define the boundaries of higher order domains. J Mol Biol 1985 3.01
8 Mutants of Escherichia coli thermosensitive for the synthesis of transfer RNA. Proc Natl Acad Sci U S A 1973 2.94
9 Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev 1996 2.78
10 The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity. Genes Dev 1994 2.57
11 Hybrid dysgenesis-induced revertants of insertions at the 5' end of the rudimentary gene in Drosophila melanogaster: transposon-induced control mutations. Genetics 1986 2.51
12 P-element-induced control mutations at the r gene of Drosophila melanogaster. Mol Cell Biol 1985 2.34
13 Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell 1990 2.33
14 Chromatin structure of the histone genes of D. melanogaster. Cell 1981 2.32
15 The primary sex determination signal of Drosophila acts at the level of transcription. Cell 1992 2.27
16 Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster. Genes Dev 1991 2.24
17 The Zw5 protein, a component of the scs chromatin domain boundary, is able to block enhancer-promoter interaction. Genes Dev 1999 2.20
18 A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex. Genetics 1997 2.18
19 Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene. Genes Dev 1989 2.17
20 Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development. Genes Dev 1988 2.13
21 Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5' splice site. Mol Cell Biol 1993 2.10
22 Two hybrid plasmids with D. melanogaster DNA sequences complementary to mRNA coding for the major heat shock protein. Cell 1978 2.10
23 The iab-7 polycomb response element maps to a nucleosome-free region of chromatin and requires both GAGA and pleiohomeotic for silencing activity. Mol Cell Biol 2001 2.03
24 The GAGA factor is required in the early Drosophila embryo not only for transcriptional regulation but also for nuclear division. Development 1996 2.03
25 Mcp and Fab-7: molecular analysis of putative boundaries of cis-regulatory domains in the bithorax complex of Drosophila melanogaster. Nucleic Acids Res 1994 2.00
26 The 5S genes of Drosophila melanogaster. Cell 1977 1.94
27 The Fab-8 boundary defines the distal limit of the bithorax complex iab-7 domain and insulates iab-7 from initiation elements and a PRE in the adjacent iab-8 domain. Development 2000 1.92
28 Physical map of two D. melanogaster DNA segments containing sequences coding for the 70,000 dalton heat shock protein. Cell 1979 1.80
29 Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions. EMBO J 1994 1.78
30 Chromatin domain boundaries in the Bithorax complex. Cell Mol Life Sci 1998 1.74
31 The Drosophila female-specific sex-determination gene, Sex-lethal, has stage-, tissue-, and sex-specific RNAs suggesting multiple modes of regulation. Genes Dev 1989 1.70
32 The Sex-lethal gene of Drosophila: DNA alterations associated with sex-specific lethal mutations. Cell 1985 1.70
33 The mcp element from the Drosophila melanogaster bithorax complex mediates long-distance regulatory interactions. Genetics 1999 1.67
34 Genes for the 70,000 dalton heat shock protein in two cloned D. melanogaster DNA segments. Cell 1979 1.66
35 The bluetail transposon: evidence for independent cis-regulatory domains and domain boundaries in the bithorax complex. EMBO J 1993 1.64
36 RNA binding by Sxl proteins in vitro and in vivo. Mol Cell Biol 1994 1.63
37 An autoregulatory feedback loop directs the localized expression of the Drosophila CPEB protein Orb in the developing oocyte. Development 2001 1.62
38 Chromatin structure of the 5S RNA genes of D. melanogaster. Cell 1980 1.58
39 Novel partitioning of DNA cleavage sites for Drosophila topoisomerase II. Cell 1985 1.55
40 Organization of the multiple genes for the 70,000-dalton heat-shock protein in Drosophila melanogaster. Proc Natl Acad Sci U S A 1979 1.55
41 The complex set of late transcripts from the Drosophila sex determination gene sex-lethal encodes multiple related polypeptides. Mol Cell Biol 1991 1.51
42 Sequence analysis and evolution of sea urchin (Lytechinus pictus and Strongylocentrotus purpuratus) histone H4 messenger RNAs. J Mol Biol 1976 1.50
43 Molecular analysis of odd-skipped, a zinc finger encoding segmentation gene with a novel pair-rule expression pattern. EMBO J 1990 1.48
44 The Drosophila orb gene is predicted to encode sex-specific germline RNA-binding proteins and has localized transcripts in ovaries and early embryos. Development 1992 1.45
45 Transvection in the Drosophila Abd-B domain: extensive upstream sequences are involved in anchoring distant cis-regulatory regions to the promoter. Genetics 1998 1.44
46 The Drosophila CPEB homolog, orb, is required for oskar protein expression in oocytes. Dev Biol 1999 1.39
47 Regulated splicing of the Drosophila sex-lethal male exon involves a blockage mechanism. Mol Cell Biol 1993 1.38
48 The cloning of the Bar region and the B breakpoint in Drosophila melanogaster: evidence for a transposon-induced rearrangement. Genetics 1989 1.37
49 Analysis of the doublesex female protein in Drosophila melanogaster: role on sexual differentiation and behavior and dependence on intersex. Genetics 1999 1.36
50 Chromatin structure, not DNA sequence specificity, is the primary determinant of topoisomerase II sites of action in vivo. Mol Cell Biol 1991 1.32
51 Expression of the Sex-lethal gene is controlled at multiple levels during Drosophila oogenesis. Development 1993 1.30
52 The dorsal protein is distributed in a gradient in early Drosophila embryos. Cell 1988 1.29
53 Topoisomerase II cleavage in chromatin. J Mol Biol 1986 1.26
54 Transfer RNA genes of Drosophila melanogaster. Nucleic Acids Res 1980 1.25
55 Novobiocin blocks the Drosophila heat shock response. J Mol Biol 1985 1.25
56 Multiple response elements in the Sex-lethal early promoter ensure its female-specific expression pattern. Mol Cell Biol 1995 1.19
57 A functional requirement for modification of the wobble nucleotide in tha anticodon of a T4 suppressor tRNA. Cell 1976 1.19
58 scute (sis-b) function in Drosophila sex determination. Mol Cell Biol 1995 1.18
59 Chromatin organization of the 87A7 heat shock locus of Drosophila melanogaster. J Mol Biol 1984 1.17
60 Chromatin fine structure of the histone gene complex of Drosophila melanogaster. Nucleic Acids Res 1983 1.15
61 In vitro processing of E. coli tRNA precursors. Cell 1976 1.13
62 The rudimentary locus of Drosophila melanogaster. J Mol Biol 1984 1.13
63 Evolution of Drosophila repetitive-dispersed DNA. J Mol Evol 1983 1.13
64 Hedgehog signaling in germ cell migration. Cell 2001 1.10
65 Processing of E. coli tRNA precursors. Brookhaven Symp Biol 1975 1.10
66 Sex-lethal, a link between sex determination and sexual differentiation in Drosophila melanogaster. Cold Spring Harb Symp Quant Biol 1985 1.08
67 Sex-specific control of Sex-lethal is a conserved mechanism for sex determination in the genus Drosophila. Development 1996 1.06
68 The dynamics of chromatin condensation: redistribution of topoisomerase II in the 87A7 heat shock locus during induction and recovery. Mol Cell Biol 1993 1.05
69 Sequence dependence of Drosophila topoisomerase II in plasmid relaxation and DNA binding. J Mol Biol 1987 1.04
70 Molecular organization of the rudimentary gene of Drosophila melanogaster. J Mol Biol 1986 1.03
71 Multiple cis-acting targeting sequences are required for orb mRNA localization during Drosophila oogenesis. Mol Cell Biol 1994 1.03
72 Isolation of the dorsal locus of Drosophila. Nature 1984 1.03
73 The JAK/STAT signaling pathway is required for the initial choice of sexual identity in Drosophila melanogaster. Mol Cell 2000 1.02
74 Direct activation of Sex-lethal transcription by the Drosophila runt protein. Development 1999 1.01
75 Isolation and sequence analysis of sea urchin (Lytechinus pictus) histone H4 messenger RNA. J Mol Biol 1976 1.01
76 Sex determination in the Drosophila germline is dictated by the sexual identity of the surrounding soma. Genetics 2000 1.01
77 DNA sequences flanking the starts of the hsp 70 and alpha beta heat shock genes are homologous. Dev Biol 1981 0.99
78 Activities of the Sex-lethal protein in RNA binding and protein:protein interactions. Nucleic Acids Res 1998 0.99
79 Transcription of adenovirus and HeLa cell genes in the presence of drugs that inhibit topoisomerase I and II function. Nucleic Acids Res 1990 0.98
80 Requirement for engrailed and invected genes reveals novel regulatory interactions between engrailed/invected, patched, gooseberry and wingless during Drosophila neurogenesis. Development 1997 0.97
81 The Drosophila miti-mere gene, a member of the POU family, is required for the specification of the RP2/sibling lineage during neurogenesis. Development 1994 0.97
82 Topoisomerase I and II cleavage of adenovirus DNA in vivo: both topoisomerase activities appear to be required for adenovirus DNA replication. J Virol 1990 0.96
83 Ribosomal RNA genes of Drosophila melanogaster have a novel chromatin structure. J Mol Biol 1984 0.96
84 The miti-mere and pdm1 genes collaborate during specification of the RP2/sib lineage in Drosophila neurogenesis. Mol Cell Biol 1995 0.95
85 GAGA factor isoforms have distinct but overlapping functions in vivo. Mol Cell Biol 2001 0.95
86 Messenger RNAs for individual histone proteins: fingerprint analysis and in vitro translation. Cold Spring Harb Symp Quant Biol 1974 0.94
87 Gene expression during Drosophila melanogaster oogenesis: analysis by in situ hybridization to tissue sections. Dev Biol 1984 0.93
88 Genomic organization and functional analysis of a deletion variant of the 87A7 heat shock locus of Drosophila melanogaster. J Mol Biol 1982 0.93
89 Transcriptionally active chromatin is sensitive to Neurospora crassa and S1 nucleases. J Mol Biol 1984 0.93
90 Two discrete modes of histone gene expression during oogenesis in Drosophila melanogaster. Dev Biol 1985 0.93
91 Functioning of the Drosophila orb gene in gurken mRNA localization and translation. Development 2001 0.92
92 Deletion of an insulator element by the mutation facet-strawberry in Drosophila melanogaster. Genetics 2000 0.92
93 Remembrance of things past: maintaining gene expression patterns with altered chromatin. Curr Opin Genet Dev 1997 0.91
94 A Drosophila melanogaster transfer RNA gene cluster at the cytogenetic locus 90BC. J Mol Biol 1984 0.89
95 Internal promoter elements of transfer RNA genes are preferentially exposed in chromatin. J Mol Biol 1984 0.89
96 Purification of a protein from unfertilized eggs of Drosophila with specific affinity for a defined DNA sequence and the cloning of this DNA sequence in bacterial plasmids. Cold Spring Harb Symp Quant Biol 1978 0.88
97 Establishment of stem cell identity in the Drosophila germline. Dev Dyn 1997 0.88
98 Selection and maintenance of sexual identity in the Drosophila germline. Genetics 1995 0.87
99 Splicing of the drosophila Sex-lethal early transcripts involves exon skipping that is independent of Sex-lethal protein. RNA 1996 0.84
100 Expression of the dorsal gene. Cold Spring Harb Symp Quant Biol 1985 0.84
101 Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression. Mol Gen Genet 1986 0.80
102 Chromatin structure of the 87A7 heat-shock locus during heat induction and recovery from heat shock. Biochim Biophys Acta 1985 0.80
103 Two domains and one RNA: a molecular threesome. Nat Struct Biol 1999 0.78
104 Intimate association of 5S RNA and tRNA genes in Drosophila melanogaster. Mol Gen Genet 1982 0.78
105 Structural polymorphism in DNA. J Mol Biol 1983 0.78
106 Molecular characterization of the 5' end of the rudimentary gene in Drosophila and analysis of three P element insertions. Nucleic Acids Res 1992 0.76
107 Conservation signals location. Nature 2001 0.75
108 Neurospora crassa and S1 nuclease cleavage in hsp 83 gene chromatin. J Mol Biol 1985 0.75
109 Two non-gypsy rudimentary mutations and their suppression by mutations of suppressor of Hairy-wing in Drosophila. Mol Gen Genet 1992 0.75