Published in Cell on August 01, 1978
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Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Cell (1986) 5.00
A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell (1984) 4.95
The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res (1987) 4.92
Control elements of the Drosophila segmentation gene fushi tarazu. Cell (1985) 4.83
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Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell (1991) 4.37
Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins. Nature (1984) 4.33
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Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell (1987) 3.91
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Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell (1997) 3.47
Genomic and cDNA clones of the homeotic locus Antennapedia in Drosophila. EMBO J (1983) 3.47
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Positive autoregulation of sex-lethal by alternative splicing maintains the female determined state in Drosophila. Cell (1991) 3.43
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Extensive regions of homology in front of the two hsp70 heat shock variant genes in Drosophila melanogaster. J Mol Biol (1981) 3.25
Calcium depletion dissociates and activates heterodimeric notch receptors. Mol Cell Biol (2000) 3.15
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Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature (1987) 2.81
A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene. Development (1994) 2.78
Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex. Genes Dev (1996) 2.78
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Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development. Cell (1984) 2.72
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nat Genet (1992) 2.71
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol (1995) 2.69
PAX-6 in development and evolution. Annu Rev Neurosci (1997) 2.68
Isolation of a homoeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts. Nature (1990) 2.67
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The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity. Genes Dev (1994) 2.57
Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J (1988) 2.57
Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development (1998) 2.56
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Hybrid dysgenesis-induced revertants of insertions at the 5' end of the rudimentary gene in Drosophila melanogaster: transposon-induced control mutations. Genetics (1986) 2.51
Expression of the caudal gene in the germ line of Drosophila: formation of an RNA and protein gradient during early embryogenesis. Cell (1987) 2.50
Spatial distribution of Antennapedia transcripts during Drosophila development. EMBO J (1983) 2.50
Participation of nuclear genes in chloroplast gene expression. Biochimie (2000) 2.50
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature (1993) 2.49
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2. Mol Cell Biol (1997) 2.48
Functional analysis and regulation of nuclear import of dorsal during the immune response in Drosophila. EMBO J (1995) 2.48
Nuclear magnetic resonance solution structure of the fushi tarazu homeodomain from Drosophila and comparison with the Antennapedia homeodomain. J Mol Biol (1994) 2.43
P-element-induced control mutations at the r gene of Drosophila melanogaster. Mol Cell Biol (1985) 2.34
Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell (1990) 2.33
Chromatin structure of the histone genes of D. melanogaster. Cell (1981) 2.32
Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science (1996) 2.31
Selective translation of heat shock mRNA in Drosophila melanogaster depends on sequence information in the leader. EMBO J (1985) 2.30
The primary sex determination signal of Drosophila acts at the level of transcription. Cell (1992) 2.27
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Developmental distribution of female-specific Sex-lethal proteins in Drosophila melanogaster. Genes Dev (1991) 2.24
The Drosophila sloppy paired locus encodes two proteins involved in segmentation that show homology to mammalian transcription factors. Genes Dev (1992) 2.24
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Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis. Science (1988) 2.23
Isolation of a hybrid plasmid with homologous sequences to a transposing element of Drosophila melanogaster. Cell (1980) 2.23
Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med (2010) 2.21
The Zw5 protein, a component of the scs chromatin domain boundary, is able to block enhancer-promoter interaction. Genes Dev (1999) 2.20
A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex. Genetics (1997) 2.18
Mutation at the Chlamydomonas nuclear NAC2 locus specifically affects stability of the chloroplast psbD transcript encoding polypeptide D2 of PS II. Cell (1989) 2.17
Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster. Proc Natl Acad Sci U S A (1983) 2.17
Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS. Neuron (1997) 2.17
Molecular analysis of the armadillo locus: uniformly distributed transcripts and a protein with novel internal repeats are associated with a Drosophila segment polarity gene. Genes Dev (1989) 2.17
Regulation of Antennapedia transcript distribution by the bithorax complex in Drosophila. Nature (1984) 2.16
Nucleotide sequence of the DdeI restriction-modification system and characterization of the methylase protein. Nucleic Acids Res (1987) 2.14
Molecular characterization of daughterless, a Drosophila sex determination gene with multiple roles in development. Genes Dev (1988) 2.13
Sex-lethal autoregulation requires multiple cis-acting elements upstream and downstream of the male exon and appears to depend largely on controlling the use of the male exon 5' splice site. Mol Cell Biol (1993) 2.10
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats. Development (1995) 2.09