Published in Br J Pharmacol on December 01, 1986
Intracellular pH regulation in resting and contracting segments of rat mesenteric resistance vessels. J Physiol (1988) 1.39
Alpha-adrenoceptor subtypes in dog saphenous vein that mediate contraction and inositol phosphate production. Br J Pharmacol (1991) 0.87
Noradrenaline stimulation of the phosphoinositide system: evidence for a novel hydrophobic inositol-containing compound in resistance arterioles. Br J Pharmacol (1988) 0.83
Opiates distinguish spinal excitation from inhibition evoked by noxious heat stimuli in the rat: relevance to theories of analgesia. Br J Pharmacol (1988) 0.82
Differences in inositol phosphate production in blood vessels of normotensive and spontaneously hypertensive rats. Br J Pharmacol (1991) 0.81
Mustard oil excites but does not inhibit nociceptive dorsal horn neurones in the rat: a presumed effect on A-delta fibres. Br J Pharmacol (1988) 0.75
Symphony of vascular contraction: how smooth muscle cells lose harmony to signal increased vascular resistance in hypertension. Hypertension (2014) 0.75
Membrane transport of ions in hypertension. Cardiovasc Drugs Ther (1990) 0.75
Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature (1984) 25.71
Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands. Biochem J (1982) 8.16
Inositol trisphosphate-induced calcium release and contraction in vascular smooth muscle. Proc Natl Acad Sci U S A (1985) 2.89
Increase in cytosolic calcium and phosphoinositide metabolism induced by angiotensin II and [Arg]vasopressin in vascular smooth muscle cells. J Biol Chem (1985) 1.43
Cytosolic free calcium levels in monolayers of cultured rat aortic smooth muscle cells. Effects of angiotensin II and vasopressin. J Biol Chem (1985) 1.38
The relationships between receptor binding capacity for norepinephrine, angiotensin II, and vasopressin and release of inositol trisphosphate, Ca2+ mobilization, and phosphorylase activation in rat liver. Mol Pharmacol (1985) 1.29
Angiotensin increases inositol trisphosphate and calcium in vascular smooth muscle. Hypertension (1985) 1.24
Pre- and postjunctional supersensitivity of the mesenteric artery preparation from normotensive and hypertensive rats. Naunyn Schmiedebergs Arch Pharmakol (1970) 1.11
Changes in noradrenaline sensitivity and morphology of arterial resistance vessels during development of high blood pressure in spontaneously hypertensive rats. Hypertension (1980) 0.98
Phosphoinositide hydrolysis is correlated with agonist-induced calcium flux and contraction in the rabbit aorta. Eur J Pharmacol (1985) 0.95
Neurogenic and humoral factors controlling vascular resistance in the spontaneously hypertensive rat. Circ Res (1974) 0.94
Activation of alpha 1-adrenoceptors increases [3H]inositol metabolism in rat vas deferens and caudal artery. Eur J Pharmacol (1985) 0.94
Dissociation constant of the norepinephrine-receptor complex in normotensive and hypertensive rats. Circ Res (1975) 0.91
Changes in renal vascular reactivity at various stages of deoxycorticosterone hypertension in rats. Circ Res (1980) 0.89
Are isolated femoral resistance vessels or tail arteries good models for the hindquarter vasculature of spontaneously hypertensive rats? Acta Physiol Scand (1982) 0.87
"Spare" alpha 1-adrenergic receptors and the potency of agonists in rat vas deferens. Mol Pharmacol (1984) 0.86
Cellular basis for increased sensitivity of vascular smooth muscle in spontaneously hypertensive rats. Circ Res (1976) 0.86
Neural and non-neural mechanisms in spontaneous hypertension. Clin Sci Mol Med Suppl (1976) 0.85
Polyphosphoinositide metabolism in erythrocytes of spontaneously hypertensive rats. Biochem Pharmacol (1981) 0.83
Altered turnover of polyphosphoinositides in the erythrocyte membrane of the spontaneously hypertensive rat. Hypertension (1983) 0.81
Relationship between developmental changes in angiotensin II-induced contractions and stimulation of phosphatidylinositol labeling of rat aorta. J Pharmacol Exp Ther (1984) 0.79
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res (1994) 8.57
Salt saga continued. BMJ (1988) 2.66
Influence of cimetidine on pharmacokinetics of propranolol. Br Med J (Clin Res Ed) (1981) 2.50
Hyperlipidaemia, hypertension, and coronary heart disease. Lancet (1995) 2.28
Upregulated TRPC1 channel in vascular injury in vivo and its role in human neointimal hyperplasia. Circ Res (2006) 2.22
Guidelines on guidelines. J Hypertens (1993) 2.11
Hydrallazine in hypertension: is there a safe dose? Br Med J (1980) 1.99
Vascular remodeling. Hypertension (1996) 1.99
Medical ethics: some reservations. J Med Ethics (1982) 1.98
Practice guidelines for primary care physicians: 2003 ESH/ESC hypertension guidelines. J Hypertens (2003) 1.93
The amplifier hypothesis: permission to dissent? J Hypertens (1999) 1.73
Do we need more anti-hypertensive drugs: lessons from the new biology. Lancet (1995) 1.65
Intravenous infusion of magnesium sulphate after acute myocardial infarction: effects on arrhythmias and mortality. Int J Cardiol (1986) 1.65
Effect of antihypertensive treatment on small arteries of patients with previously untreated essential hypertension. Hypertension (1995) 1.62
First line treatment in hypertension. BMJ (1990) 1.58
Salt and hypertension. Lancet (1984) 1.52
Value of ambulatory intra-arterial blood pressure monitoring in the long-term prediction of left ventricular hypertrophy and carotid atherosclerosis in essential hypertension. J Hum Hypertens (1999) 1.49
Evidence-based medicine and hypertension. J Hypertens (1999) 1.43
Antihypertensive drugs and plasma lipids. Br Heart J (1991) 1.42
31P nuclear magnetic resonance measurement of free erythrocyte magnesium concentration in man and its relation to blood pressure. Clin Sci (Lond) (1988) 1.40
Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries. Br J Pharmacol (2004) 1.29
Effect of aging on the prognostic significance of ambulatory systolic, diastolic, and pulse pressure in essential hypertension. Circulation (2001) 1.26
Leucocyte membrane sodium transport in normotensive populations: dissociation of abnormalities of sodium efflux from raised blood-pressure. Lancet (1982) 1.26
Pulse pressure and resistance artery structure in the elderly. Hypertension (1995) 1.23
Further observations on renal transplants in man from cadaveric donors. Br Med J (1966) 1.22
Ion transport in hypertension. Biosci Rep (1982) 1.21
Failure of ranitidine to interact with propranolol. Br Med J (Clin Res Ed) (1982) 1.18
Treating hypertension. J Hypertens (1996) 1.17
Racial variation in cardiovascular morbidity and mortality in essential hypertension. Heart (2000) 1.17
Dietary salt and hypertension. Lancet (1980) 1.16
Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation--contraction coupling in isolated resistance vessels from essential hypertensives. Circ Res (1987) 1.13
Thoughts on the Reith lectures. Lancet (1981) 1.12
Influence of dietary linoleic acid on leucocyte sodium transport and blood pressure. Br Med J (Clin Res Ed) (1986) 1.11
Converting enzyme inhibitor and saralasin infusion in rats. Evidence for an additional vasodepressor property of converting enzyme inhibitor. Circ Res (1978) 1.11
The involvement of matrix glycoproteins in vascular calcification and fibrosis: an immunohistochemical study. J Pathol (2002) 1.11
Magnesium deficiency and diuretics. Br Med J (Clin Res Ed) (1982) 1.10
Prediction of coronary and cerebrovascular morbidity and mortality by direct continuous ambulatory blood pressure monitoring in essential hypertension. Circulation (1999) 1.09
Cimetidine and bioavailability of propranolol. Lancet (1981) 1.08
Arterial wall or plasma renin in hypertension? Clin Sci (Lond) (1979) 1.07
Salt substitutes and potassium intake. BMJ (1991) 1.05
Vasodepressor property of the converting enzyme inhibitor captopril (SQ 14 225): the role of factors other than renin-angiotensin blockade in the rat. Clin Sci (Lond) (1980) 1.04
Hepatocyte growth factor and c-Met expression in pericytes: implications for atherosclerotic plaque development. J Pathol (2007) 1.01
Myogenic tone in mesenteric arteries from spontaneously hypertensive rats. Am J Physiol (1996) 1.01
The dntidiuretic action of diazoxide. Clin Sci (1972) 1.01
Membrane-associated diacylglycerol kinase activity is increased by noradrenaline, but not by angiotensin II, in arterial smooth muscle. Biochem J (1994) 1.01
Comparison of small artery sensitivity and morphology in pressurized and wire-mounted preparations. Am J Physiol (1995) 0.99
Obesity, diabetes and atrial fibrillation; epidemiology, mechanisms and interventions. Curr Cardiol Rev (2012) 0.98
Hyperaluminaemia form aluminium resins. Lancet (1970) 0.98
Histology of subcutaneous small arteries from patients with essential hypertension. Hypertension (1993) 0.98
Abnormal baroreceptor-cardiac reflex sensitivity is not detected by conventional tests of autonomic function in patients with insulin-dependent diabetes mellitus. Clin Sci (Lond) (1996) 0.97
Pharmacokinetics and pharmacodynamics of nifedipine infusion in normal volunteers. Br J Clin Pharmacol (1987) 0.94
Treatment of refractory hypertension. Lancet (1982) 0.94
Insertion/deletion polymorphism in the angiotensin-converting enzyme gene and risk of restenosis after coronary angioplasty. Lancet (1995) 0.93
Expression of the renin gene in extra-renal tissues of the rat. Biochem J (1988) 0.93
Adventitial cells do not contribute to neointimal mass after balloon angioplasty of the rat common carotid artery. Circulation (2001) 0.93
Dietary supplementation with marine fish oil improves in vitro small artery endothelial function in hypercholesterolemic patients: a double-blind placebo-controlled study. Circulation (1997) 0.93
Blood pressure response of nephrectomized hypertensive rats to converting enzyme inhibition: evidence for persistent vascular renin activity. Clin Sci Mol Med (1977) 0.92
Reversal of two-kidney one clip renovascular hypertension in the rat. Hypertension (1980) 0.90
Identification of protein kinase C isoforms in rat mesenteric small arteries and their possible role in agonist-induced contraction. Circ Res (1996) 0.90
Vascular renin-like activity and blood pressure maintenance in the rat. Studies of the effect of changes in sodium balance, hypertension and nephrectomy. Hypertension (1980) 0.90
Aluminium and chronic renal failure. Br Med J (1971) 0.89
Involvement of tyrosine phosphorylation in endothelin-1-induced calcium-sensitization in rat small mesenteric arteries. Br J Pharmacol (1997) 0.89
Contribution of VCAF-positive cells to neovascularization and calcification in atherosclerotic plaque development. J Pathol (2007) 0.89
Salt intake and diuretic treatment of hypertension. Lancet (1979) 0.89
Stimulated release of a hyperpolarizing factor (ADHF) from mesenteric artery perivascular adipose tissue: involvement of myocyte BKCa channels and adiponectin. Br J Pharmacol (2013) 0.89
Assessment of baroreceptor-cardiac reflex sensitivity using time domain analysis in patients with IDDM and the relation to left ventricular mass index. Diabetologia (1996) 0.88
Acute inotropic effects of intravenous nifedipine and its vehicle compared with saline: a double-blind study of systolic time intervals in normal subjects. Br J Clin Pharmacol (1988) 0.88
Low renin hypertension. A distinct entity. Lancet (1976) 0.88
Plasma renin and angiotensin II measurement in hypertensive and normal subjects: correlation of basal and stimulated states. J Clin Endocrinol Metab (1977) 0.88
Detection of renin messenger RNA in rat tissues: increased sensitivity using an RNAse protection technique. J Hypertens Suppl (1987) 0.87
Studies of isolated resistance vessels from offspring of essential hypertensive patients. Hypertension (1987) 0.87
Erythraemia in renal transplantation. Br Med J (1969) 0.87
Dietary fat in relation to fatty acid composition of red cells and adipose tissue in colorectal cancer. Br J Cancer (1988) 0.87
Lipid second messengers derived from glycerolipids and sphingolipids, and their role in smooth muscle function. Acta Physiol Scand (1998) 0.87
Guidelines for management of hypertension. Sticking to guidelines can be expensive. BMJ (1994) 0.87
Sodium conservation in chronic renal failure: studies using oral diazoxide. Clin Sci (1972) 0.87
Vascular angiotensin II receptors and sodium balance in rats. Role of kidneys and vascular renin activity. Circ Res (1975) 0.86
Aluminium retention and toxicity in chronic renal failure. Lancet (1972) 0.86
Arterial wall uptake of renal renin and blood pressure control. Hypertension (1983) 0.86
A double-blind randomized cross-over study of the efficacy and tolerability of nifedipine and nitrendipine in the treatment of mild to moderate hypertension. Br J Clin Pharmacol (1989) 0.86
The influence of pH, bicarbonate and hypertonicity on the absorption of ammonia from the rat intestine. Clin Sci (1970) 0.86
Impaired flow-dependent dilatation in distal mesenteric arteries from the spontaneously hypertensive rat. J Physiol (1999) 0.85
In vitro perfusion studies of resistance artery function in genetic hypertension. Hypertension (1993) 0.85
Neurotransmission in human resistance arteries: contribution of alpha 1- and alpha 2-adrenoceptors but not P 2-purinoceptors. J Vasc Res (1992) 0.85
Calcium antagonists in hypertension: relation to abnormal sodium transport. Br Med J (Clin Res Ed) (1983) 0.85
Healed experimental renal papillary necrosis. J Pathol (1973) 0.85
Dangers in treating hyponatremia. Br Med J (Clin Res Ed) (1987) 0.85
Effects of protection from pressure on resistance artery morphology and reactivity in spontaneously hypertensive and Wistar-Kyoto rats. Circ Res (1991) 0.85
Effects of treatment for hypertension on cerebral haemorrhage and infarction. Br Med J (Clin Res Ed) (1984) 0.84
The phosphoinositide signalling system and hypertension. J Hypertens (1987) 0.84
Endothelin-1 stimulates hydrolysis of phosphatidylcholine by phospholipases C and D in intact rat mesenteric arteries. J Vasc Res (1999) 0.84