|
1
|
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.
|
Science
|
1985
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95.08
|
|
2
|
A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions.
|
Nucleic Acids Res
|
1988
|
26.70
|
|
3
|
Analysis of enzymatically amplified beta-globin and HLA-DQ alpha DNA with allele-specific oligonucleotide probes.
|
Nature
|
1986
|
17.77
|
|
4
|
Amplification and analysis of DNA sequences in single human sperm and diploid cells.
|
Nature
|
1988
|
10.84
|
|
5
|
Characterization of beta-thalassaemia mutations using direct genomic sequencing of amplified single copy DNA.
|
Nature
|
1987
|
8.58
|
|
6
|
Isolation, characterization, and expression in Escherichia coli of the DNA polymerase gene from Thermus aquaticus.
|
J Biol Chem
|
1989
|
4.96
|
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7
|
High-level expression, purification, and enzymatic characterization of full-length Thermus aquaticus DNA polymerase and a truncated form deficient in 5' to 3' exonuclease activity.
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PCR Methods Appl
|
1993
|
4.83
|
|
8
|
Analysis of DNA extracted from formalin-fixed, paraffin-embedded tissues by enzymatic amplification and hybridization with sequence-specific oligonucleotides.
|
Biochem Biophys Res Commun
|
1987
|
4.05
|
|
9
|
Rapid prenatal diagnosis of sickle cell anemia by a new method of DNA analysis.
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N Engl J Med
|
1987
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3.44
|
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10
|
T-DNA from Agrobacterium Ti plasmid is in the nuclear DNA fraction of crown gall tumor cells.
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Proc Natl Acad Sci U S A
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1980
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3.32
|
|
11
|
Analysis of RAS gene mutations in acute myeloid leukemia by polymerase chain reaction and oligonucleotide probes.
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Proc Natl Acad Sci U S A
|
1988
|
2.99
|
|
12
|
Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma.
|
Cancer Res
|
1993
|
2.22
|
|
13
|
Rapid prenatal diagnosis of beta thalassemia using DNA amplification and nonradioactive probes.
|
Blood
|
1989
|
0.92
|
|
14
|
Genetic diversity within the HLA class II region: ten new DPB1 alleles and their population distribution.
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Tissue Antigens
|
1992
|
0.89
|
|
15
|
Analysis of 16 cystic fibrosis mutations in Mexican patients.
|
Am J Med Genet
|
1997
|
0.80
|
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16
|
Prenatal diagnosis of alpha-thalassemia by polymerase chain reaction and dual restriction enzyme analysis.
|
Hum Genet
|
1990
|
0.79
|
|
17
|
T-DNA of a crown gall teratoma is covalently joined to host plant DNA.
|
Nature
|
1980
|
0.77
|
|
18
|
Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. 1985.
|
Biotechnology
|
1992
|
0.76
|
|
19
|
Genetic markers of male infertility: Y chromosome microdeletions and cystic fibrosis transmembrane conductance gene mutations.
|
Croat Med J
|
2001
|
0.75
|
|
20
|
Issues in implementing prenatal screening for cystic fibrosis: results of a working conference.
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Genet Med
|
2001
|
0.75
|
|
21
|
Molecular analysis of northwestern Mexican patients with cystic fibrosis: screening of 10 known mutations. Mutations in brief no. 185. Online.
|
Hum Mutat
|
1998
|
0.75
|