Published in Cell on December 23, 1988
The RCC1 protein, a regulator for the onset of chromosome condensation locates in the nucleus and binds to DNA. J Cell Biol (1989) 4.13
Genetic control of cell division patterns in the Drosophila embryo. Cell (1989) 4.03
Mutations of p34cdc2 phosphorylation sites induce premature mitotic events in HeLa cells: evidence for a double block to p34cdc2 kinase activation in vertebrates. EMBO J (1991) 3.23
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An early embryonic product of the gene shaggy encodes a serine/threonine protein kinase related to the CDC28/cdc2+ subfamily. EMBO J (1990) 2.00
Complementation of snf1, a mutation affecting global regulation of carbon metabolism in yeast, by a plant protein kinase cDNA. Proc Natl Acad Sci U S A (1991) 1.83
Structure and developmental expression of the chicken CDC2 kinase. EMBO J (1989) 1.80
Xenopus homolog of the mos protooncogene transforms mammalian fibroblasts and induces maturation of Xenopus oocytes. Proc Natl Acad Sci U S A (1989) 1.69
A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4. Mol Cell Biol (1994) 1.62
Avian reticuloendotheliosis virus-transformed lymphoid cells contain multiple pp59v-rel complexes. J Virol (1990) 1.57
Mutation of the hamster cell cycle gene RCC1 is complemented by the homologous genes of Drosophila and S.cerevisiae. EMBO J (1991) 1.39
Identification of a 42-kilodalton phosphotyrosyl protein as a serine(threonine) protein kinase by renaturation. Mol Cell Biol (1990) 1.38
Regulation of Saccharomyces cerevisiae CDC7 function during the cell cycle. Mol Biol Cell (1993) 1.29
Identification of ras-related, YPT family genes in Schizosaccharomyces pombe. EMBO J (1990) 1.26
Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells. Proc Natl Acad Sci U S A (1990) 1.23
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Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos. J Cell Biol (1990) 1.12
Crystal structure of the cell cycle-regulatory protein suc1 reveals a beta-hinge conformational switch. Proc Natl Acad Sci U S A (1995) 1.10
The crystal structure of p13suc1, a p34cdc2-interacting cell cycle control protein. EMBO J (1995) 1.08
A repertoire of cell cycle regulators whose expression is coordinated with human cytotrophoblast differentiation. Am J Pathol (2000) 0.92
A cdc2-like kinase phosphorylates histone H1 in the amitotic macronucleus of Tetrahymena. EMBO J (1991) 0.89
Clostridium botulinum C2 toxin delays entry into mitosis and activation of p34cdc2 kinase and cdc25-C phosphatase in HeLa cells. Infect Immun (1999) 0.85
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Regulation of maintenance DNA methylation via histone ubiquitylation. J Biochem (2015) 0.77
Growth factor-dependent initiation of DNA replication in nuclei isolated from an interleukin 3-dependent murine myeloid cell line. J Clin Invest (1990) 0.75
The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis. Cell (1988) 6.45
Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell (1991) 4.33
Completion of DNA replication is monitored by a feedback system that controls the initiation of mitosis in vitro: studies in Xenopus. Cell (1990) 3.68
Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase. Cell (1989) 3.56
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Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggs. Cell (1983) 3.21
Systems for the study of nuclear assembly, DNA replication, and nuclear breakdown in Xenopus laevis egg extracts. Methods Cell Biol (1991) 2.76
Regulation of the cell cycle during early Xenopus development. Cell (1984) 2.73
Regulation of replicon size in Xenopus egg extracts. Science (1997) 2.32
Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2. Cell (1992) 2.31
Xenopus ATR is a replication-dependent chromatin-binding protein required for the DNA replication checkpoint. Curr Biol (2001) 2.20
Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids. I. Characterization of the binding interactions. J Mol Biol (1981) 2.19
RCC1, a regulator of mitosis, is essential for DNA replication. Mol Cell Biol (1992) 2.08
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Cdk2 kinase is required for entry into mitosis as a positive regulator of Cdc2-cyclin B kinase activity. Cell (1996) 1.84
Identification of a developmental timer regulating the stability of embryonic cyclin A and a new somatic A-type cyclin at gastrulation. Genes Dev (1995) 1.67
Distinct roles of cdk2 and cdc2 in RP-A phosphorylation during the cell cycle. J Cell Sci (1993) 1.66
Assembly/disassembly of the nuclear envelope membrane: cell cycle-dependent binding of nuclear membrane vesicles to chromatin in vitro. Cell (1991) 1.61
Autoregulation of gene expression. Quantitative evaluation of the expression and function of the bacteriophage T4 gene 32 (single-stranded DNA binding) protein system. J Mol Biol (1982) 1.57
A developmental timer regulates degradation of cyclin E1 at the midblastula transition during Xenopus embryogenesis. Proc Natl Acad Sci U S A (1996) 1.35
In vitro cell cycle arrest induced by using artificial DNA templates. Mol Cell Biol (1992) 1.34
Developmentally regulated activation of apoptosis early in Xenopus gastrulation results in cyclin A degradation during interphase of the cell cycle. Development (1997) 1.24
Mitosis-inducing factors are present in a latent form during interphase in the Xenopus embryo. J Cell Biol (1988) 1.22
On the processivity of DNA replication. J Biomol Struct Dyn (1983) 1.11
Interactions of bacteriophage T4-coded gene 32 protein with nucleic acids. II. Specificity of binding to DNA and RNA. J Mol Biol (1981) 1.10
Cloning and characterization of Xenopus cdc2, a component of MPF. Cold Spring Harb Symp Quant Biol (1991) 1.06
On the thermodynamics and kinetics of the cooperative binding of bacteriophage T4-coded gene 32 (helix destabilizing) protein to nucleic acid lattices. Biophys J (1980) 1.00
Stimulation of the processivity of the DNA polymerase of bacteriophage T4 by the polymerase accessory proteins. The role of ATP hydrolysis. J Biol Chem (1991) 0.98
The cell cycle dependence of protein synthesis during Xenopus laevis development. Dev Biol (1991) 0.86
Neurohormonal and neuromodulatory control of sleep in Drosophila. Cold Spring Harb Symp Quant Biol (2007) 0.86
The cell cycle dependence of the secretory pathway in developing Xenopus laevis. Dev Biol (1991) 0.78
Assembly/disassembly of the nuclear envelope membrane. Characterization of the membrane-chromatin interaction using partially purified regulatory enzymes. J Biol Chem (1995) 0.77
Nuclear envelope assembly following mitosis. Methods Enzymol (1992) 0.77
DNA replication and progression through the cell cycle. Ciba Found Symp (1992) 0.76