Published in Essays Neurochem Neuropharmacol on January 01, 1977
Neurotoxicity and metabolism of the catecholamine-derived 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde: the role of aldehyde dehydrogenase. Pharmacol Rev (2007) 1.72
Metabolism of daunorubicin by a barbiturate-sensitive aldehyde reductase from rat liver. Biochem J (1976) 0.79
Kinetic studies with the low-Km aldehyde reductase from ox brain. Biochem J (1985) 0.78
A comparative study of aldehyde dehydrogenase and alcohol dehydrogenase activities in crucian carp and three other vertebrates: apparent adaptations to ethanol production. J Comp Physiol B (1988) 0.77
Metaldehyde poisoning from slug bait ingestion. West J Med (1982) 0.75
A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem (2000) 4.21
Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production. Nature (1986) 3.41
Purification and characterization of smooth muscle cell caveolae. J Cell Biol (1994) 3.18
mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J (2001) 2.86
Membrane protein secretases. Biochem J (1997) 2.70
The metabolism of neuropeptides. The hydrolysis of peptides, including enkephalins, tachykinins and their analogues, by endopeptidase-24.11. Biochem J (1984) 2.56
The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics (1997) 2.55
Serological diagnosis of syphilis. PHLS Syphilis Serology Working Group. Commun Dis Public Health (2000) 2.52
Substance P and [Leu]enkephalin are hydrolyzed by an enzyme in pig caudate synaptic membranes that is identical with the endopeptidase of kidney microvilli. Proc Natl Acad Sci U S A (1983) 2.37
Negatively co-operative ligand binding. Biochem J (1973) 2.36
Cholesterol is excluded from the phospholipid annulus surrounding an active calcium transport protein. Nature (1975) 2.30
Activation of two signal-transduction systems in hepatocytes by glucagon. Nature (1986) 2.21
A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes. Biochem J (1980) 2.14
The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it. Biochim Biophys Acta (1976) 2.07
Annular lipids determine the ATPase activity of a calcium transport protein complexed with dipalmitoyllecithin. Biochemistry (1976) 2.06
Is an early calcium flux necessary to stimulate lymphocytes? Nature (1977) 2.03
Kinetic analysis of progress curves. Methods Enzymol (1979) 1.98
A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proc Natl Acad Sci U S A (1997) 1.95
Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature (1987) 1.93
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis. Br J Pharmacol (2009) 1.89
Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor. Biochem J (1988) 1.85
The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579. EMBO J (1999) 1.85
Purification of endopeptidase-24.11 ('enkephalinase') from pig brain by immunoadsorbent chromatography. Biochem J (1983) 1.85
Insulin and glucagon regulate the activation of two distinct membrane-bound cyclic AMP phosphodiesterases in hepatocytes. Biochem J (1983) 1.82
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J Biol Chem (1999) 1.77
Effects of pH on enzymes. Methods Enzymol (1979) 1.77
Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping. Pharmacogenetics (1999) 1.74
Chronic norovirus infection in pediatric hematopoietic stem cell transplant recipients: a cause of prolonged intestinal failure requiring intensive nutritional support. Pediatr Transplant (2011) 1.72
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions. J Biol Chem (2000) 1.68
The sub-mitochondrial localization of monoamine oxidase in rat liver and brain. Biochim Biophys Acta (1967) 1.62
Purification and properties of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes. Biochem J (1981) 1.58
Kidney neutral endopeptidase and the hydrolysis of enkephalin by synaptic membranes show similar sensitivity to inhibitors. Biochem J (1982) 1.58
Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes. Biochem J (1983) 1.53
The use of 7-amino actinomycin D in identifying apoptosis: simplicity of use and broad spectrum of application compared with other techniques. Blood (1996) 1.52
Isolation of two differentially glycosylated forms of peptidyl-dipeptidase A (angiotensin converting enzyme) from pig brain: a re-evaluation of their role in neuropeptide metabolism. Biochem J (1987) 1.51
Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene. Biochem J (1997) 1.51
Changes in the form of Arrhenius plots of the activity of glucagon-stimulated adenylate cyclase and other hamster liver plasma-membrane enzymes occurring on hibernation. Biochem J (1978) 1.51
Renal dipeptidase is one of the membrane proteins released by phosphatidylinositol-specific phospholipase C. Biochem J (1987) 1.50
Membrane localization of endopeptidase-24.11 and peptidyl dipeptidase A (angiotensin converting enzyme) in the pig brain: a study using subcellular fractionation and electron microscopic immunocytochemistry. J Neurochem (1992) 1.50
Inhibition of monoamine oxidase by amphetamine and related compounds. Biochem Pharmacol (1976) 1.49
The increase in bilayer fluidity of rat liver plasma membranes achieved by the local anesthetic benzyl alcohol affects the activity of intrinsic membrane enzymes. J Biol Chem (1980) 1.49
The nature of the electrophoretically separable multiple forms of rat liver monoamine oxidase. Biochem J (1973) 1.47
Processing and metabolism of neuropeptides. Essays Biochem (1986) 1.46
cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model. Biochem J (1998) 1.46
Exchange of partners in glucagon receptor-adenylate cyclase complexes. Physical evidence for the independent, mobile receptor model. Biochim Biophys Acta (1977) 1.46
The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go. FEBS Lett (1987) 1.46
Are there neuropeptide-specific peptidases? Biochem Pharmacol (1985) 1.44
Ectoenzymes of the kidney microvillar membrane. Aminopeptidase P is anchored by a glycosyl-phosphatidylinositol moiety. FEBS Lett (1988) 1.42
Induction of apoptotic DNA fragmentation and cell death in HL-60 human promyelocytic leukemia cells by pharmacological inhibitors of protein kinase C. Cancer Res (1994) 1.41
A simple method for sequencing small DNAs by introducing precise overlapping ends into restriction digestion fragments. Nucleic Acids Res (1998) 1.40
Guanine-nucleotide-binding proteins expressed in rat white adipose tissue. Identification of both mRNAs and proteins corresponding to Gi1, Gi2 and Gi3. Biochem J (1989) 1.37
Ectoenzymes of the kidney microvillar membrane. Affinity purification, characterization and localization of the phospholipase C-solubilized form of renal dipeptidase. Biochem J (1989) 1.37
Mutant but not normal p21 ras elevates inositol phospholipid breakdown in two different cell systems. Oncogene (1988) 1.37
Hormonal regulation of Gi2 alpha-subunit phosphorylation in intact hepatocytes. Biochem J (1990) 1.37
Cleavage of Alzheimer's amyloid precursor protein by alpha-secretase occurs at the surface of neuronal cells. Biochemistry (1999) 1.36
A kinetic evaluation of monoamine oxidase activity in rat liver mitochondrial outer membranes. Biochem J (1974) 1.35
Modulation of the GABAA receptor by depressant barbiturates and pregnane steroids. Br J Pharmacol (1988) 1.35
Insulin inhibits the cholera-toxin-catalysed ribosylation of a Mr-25000 protein in rat liver plasma membranes. Biochem J (1985) 1.35
The lipid environment of the glucagon receptor regulates adenylate cyclase activity. Biochim Biophys Acta (1976) 1.34
Insulin trigger, cyclic AMP-dependent activation and phosphorylation of a plasma membrane cyclic AMP phosphodiesterase. Nature (1980) 1.34
The metabolism of neuropeptides. Phase separation of synaptic membrane preparations with Triton X-114 reveals the presence of aminopeptidase N. Biochem J (1985) 1.33
Insulin exerts actions through a distinct species of guanine nucleotide regulatory protein: inhibition of adenylate cyclase. Biochem J (1983) 1.32
Pig kidney angiotensin converting enzyme. Purification and characterization of amphipathic and hydrophilic forms of the enzyme establishes C-terminal anchorage to the plasma membrane. Biochem J (1987) 1.32
The reaction pathway of pig brain mitochondrial monoamine oxidase. Eur J Biochem (1968) 1.31
The kinetics of pig brain aldehyde dehydrogenase. Eur J Biochem (1971) 1.29
Phosphodiesterase isoforms in the pulmonary arterial circulation of the rat: changes in pulmonary hypertension. J Pharmacol Exp Ther (1997) 1.29
The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function. Mol Psychiatry (2010) 1.28
The activity of glucagon-stimulated adenylate cyclase from rat liver plasma membranes is modulated by the fluidity of its lipid environment. Biochem J (1978) 1.27
Sub-family selective actions in the ability of Erk2 MAP kinase to phosphorylate and regulate the activity of PDE4 cyclic AMP-specific phosphodiesterases. Br J Pharmacol (2000) 1.27
The purification of pig brain mitochondrial monoamine oxidase. Eur J Biochem (1968) 1.27
Diabetes-induced alterations in the expression, functioning and phosphorylation state of the inhibitory guanine nucleotide regulatory protein Gi-2 in hepatocytes. Biochem J (1990) 1.25
A case report of fowl plague keratoconjunctivitis. Br J Ophthalmol (1977) 1.24
An immunohistochemical study of endopeptidase-24.11 ("enkephalinase") in the pig nervous system. Neuroscience (1986) 1.24
Forskolin and ethanol both perturb the structure of liver plasma membranes and activate adenylate cyclase activity. Biochem Pharmacol (1983) 1.23
Characterization of the phosphorylated form of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes. Biochem J (1981) 1.23
The emerging role of ACE2 in physiology and disease. J Pathol (2007) 1.22
Purification of glutamate dehydrogenase from ox brain and liver. Evidence that commercially available preparations of the enzyme from ox liver have suffered proteolytic cleavage. Biochem J (1980) 1.21
Platelet activating factor and U44069 stimulate a GTPase activity in human platelets which is distinct from the guanine nucleotide regulatory proteins, Ns and Ni. Biochem J (1986) 1.21
Endopeptidase-24.11 and aminopeptidase activity in brain synaptic membranes are jointly responsible for the hydrolysis of cholecystokinin octapeptide (CCK-8). FEBS Lett (1984) 1.20
Cholera toxin mediated activation of adenylate cyclase in intact rat hepatocytes. FEBS Lett (1979) 1.19
Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition. J Biol Chem (1999) 1.19
UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions. J Biol Chem (2000) 1.18
The phorbol ester, TPA inhibits glucagon-stimulated adenylate cyclase activity. FEBS Lett (1984) 1.18
Identification and characterization of the type-IVA cyclic AMP-specific phosphodiesterase RD1 as a membrane-bound protein expressed in cerebellum. Biochem J (1995) 1.17
Insulin, glucagon and the receptor-mediated control of cyclic AMP concentrations in liver. Twenty-second Colworth medal lecture. Biochem Soc Trans (1986) 1.17
Kinetic studies of bovine liver carbamoyl phosphate synthetase. Biochem J (1974) 1.16
Membrane localization of cyclic nucleotide phosphodiesterase 3 (PDE3). Two N-terminal domains are required for the efficient targeting to, and association of, PDE3 with endoplasmic reticulum. J Biol Chem (2000) 1.16
The prosthetic groups of pig brain mitochondrial monoamine oxidase. Biochim Biophys Acta (1968) 1.15
Guanosine 5'-triphosphate and guanosine 5'-[beta gamma-imido]triphosphate effect a collision coupling mechanism between the glucagon receptor and catalytic unit of adenylate cyclase. Biochem J (1980) 1.14
Identification, characterization and regional distribution in brain of RPDE-6 (RNPDE4A5), a novel splice variant of the PDE4A cyclic AMP phosphodiesterase family. Biochem J (1995) 1.14
Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes. J Mol Cell Cardiol (2011) 1.14
Thrombin, unlike vasopressin, appears to stimulate two distinct guanine nucleotide regulatory proteins in human platelets. Biochem J (1986) 1.13
Islet-activating protein blocks glucagon desensitization in intact hepatocytes. Biochem J (1984) 1.13
Processing and metabolism of peptide-YY: pivotal roles of dipeptidylpeptidase-IV, aminopeptidase-P, and endopeptidase-24.11. Endocrinology (1994) 1.13
An automatic apparatus for the study of enzyme kinetics. Biochem J (1969) 1.12