Published in Nature on June 09, 1977
Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J Cell Biol (1982) 11.87
Cytoplasmic pH and free Mg2+ in lymphocytes. J Cell Biol (1982) 5.30
Voltage-gated potassium channels are required for human T lymphocyte activation. J Exp Med (1984) 2.54
Histones H1 and H5: one or two molecules per nucleosome? Nucleic Acids Res (1981) 2.33
Crosslinking by ligands to surface immunoglobulin triggers mobilization of intracellular 45Ca2+ in B lymphocytes. J Cell Biol (1979) 1.49
Early plasma-membrane-potential changes during stimulation of lymphocytes by concanavalin A. Biochem J (1983) 1.32
Analysis of prostaglandin E2 effect on T lymphocyte activation. Abrogation of prostaglandin E2 inhibitory effect by the tumor promotor 12.0 tetradecanoyl phorbol-13 acetate. J Clin Invest (1987) 1.04
The role of calcium ions in the regulation of rat thymocyte pyruvate oxidation by mitogens. Biochem J (1978) 1.02
Transglutaminase activity in human lymphocytes: early activation by phytomitogens. Proc Natl Acad Sci U S A (1978) 0.96
Mechanism of activation of pyruvate dehydrogenase by mitogens in pig lymphocytes. Biochem J (1983) 0.93
Large effects of preparative techniques on lymphocyte cyclic AMP content. Biochem J (1983) 0.87
Early transmembrane events in alloimmune cytotoxic T-lymphocyte activation as revealed by stopped-flow fluorometry. Proc Natl Acad Sci U S A (1986) 0.85
Intracellular calcium regulation and the measurement of free calcium in 2H3 cells and synaptosomes. Br J Clin Pharmacol (1985) 0.85
The isolation of lymphocyte mitochondria and their regulation of extramitochondrial free Ca2+ concentration. Biochem J (1982) 0.84
Limits to the early increase in free cytoplasmic calcium concentration during the mitogenic stimulation of lymphocytes. Biochem J (1983) 0.81
Kinetic evidence for a common mechanism of capping on lymphocytes. Biochem J (1982) 0.80
Expression and phosphorylation of the Listeria monocytogenes ActA protein in mammalian cells. Proc Natl Acad Sci U S A (1993) 3.63
Infection and spread of alphaherpesviruses in the nervous system. Adv Virus Res (1998) 3.61
Free cytoplasmic calcium concentration and the mitogenic stimulation of lymphocytes. J Biol Chem (1983) 3.44
Normal p21N-ras couples bombesin and other growth factor receptors to inositol phosphate production. Nature (1986) 3.41
Lymphocyte membrane potential assessed with fluorescent probes. Biochim Biophys Acta (1980) 3.33
Reconstitution of a calcium pump using defined membrane components. Proc Natl Acad Sci U S A (1974) 3.11
Genetic control of the circulating concentration of transforming growth factor type beta1. Hum Mol Genet (1999) 3.08
Emerging viral diseases of Southeast Asia and the Western Pacific. Emerg Infect Dis (2001) 2.91
mAKAP assembles a protein kinase A/PDE4 phosphodiesterase cAMP signaling module. EMBO J (2001) 2.86
Transforming growth factor-beta1 gene polymorphisms and coronary artery disease. Clin Sci (Lond) (1998) 2.68
The mechanism of the calcium signal and correlation with histamine release in 2H3 cells. J Biol Chem (1984) 2.58
Activities of 3'-azido-3'-deoxythymidine nucleotide dimers in primary lymphocytes infected with human immunodeficiency virus type 1. Antimicrob Agents Chemother (1990) 2.53
A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells. Nature (1985) 2.53
The serum concentration of active transforming growth factor-beta is severely depressed in advanced atherosclerosis. Nat Med (1995) 2.42
Australian bat lyssavirus infection: a second human case, with a long incubation period. Med J Aust (2000) 2.35
Cholesterol is excluded from the phospholipid annulus surrounding an active calcium transport protein. Nature (1975) 2.30
Activation of two signal-transduction systems in hepatocytes by glucagon. Nature (1986) 2.21
The calcium signal and phosphatidylinositol breakdown in 2H3 cells. J Biol Chem (1984) 2.19
Mitogens increase phosphorylation of phosphoinositides in thymocytes. Nature (1985) 2.18
The proton relaxation of benzyl alcohol in erythrocyte membranes. Mol Pharmacol (1968) 2.17
A peripheral and an intrinsic enzyme constitute the cyclic AMP phosphodiesterase activity of rat liver plasma membranes. Biochem J (1980) 2.14
High expression of genes for calcification-regulating proteins in human atherosclerotic plaques. J Clin Invest (1994) 2.13
Structure of vancomycin and its complex with acetyl-D-alanyl-D-alanine. Nature (1978) 2.09
The glucagon receptor of rat liver plasma membrane can couple to adenylate cyclase without activating it. Biochim Biophys Acta (1976) 2.07
Annular lipids determine the ATPase activity of a calcium transport protein complexed with dipalmitoyllecithin. Biochemistry (1976) 2.06
Hepatitis A outbreaks among illicit drug users and their contacts in Queensland, 1997. Med J Aust (1999) 2.05
Cap formation by various ligands on lymphocytes shows the same dependence on high cellular ATP levels. Biochim Biophys Acta (1980) 2.03
A subset of olfactory neurons that selectively express cGMP-stimulated phosphodiesterase (PDE2) and guanylyl cyclase-D define a unique olfactory signal transduction pathway. Proc Natl Acad Sci U S A (1997) 1.95
Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature (1987) 1.93
Apremilast, a cAMP phosphodiesterase-4 inhibitor, demonstrates anti-inflammatory activity in vitro and in a model of psoriasis. Br J Pharmacol (2009) 1.89
Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells. Circ Res (1993) 1.88
Tamoxifen elevates transforming growth factor-beta and suppresses diet-induced formation of lipid lesions in mouse aorta. Nat Med (1995) 1.88
Activation of transforming growth factor-beta is inhibited in transgenic apolipoprotein(a) mice. Nature (1994) 1.87
The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579. EMBO J (1999) 1.85
13 C nuclear magnetic resonance relaxation measurements of synthetic lecithins and the effect of spin-labeled lipids. Biochemistry (1972) 1.83
Insulin and glucagon regulate the activation of two distinct membrane-bound cyclic AMP phosphodiesterases in hepatocytes. Biochem J (1983) 1.82
An evaluation of a safety education program for kindergarten and elementary school children. Arch Pediatr Adolesc Med (2000) 1.81
Effect of light on biomass and community structure of estuarine detrital microbiota. Appl Environ Microbiol (1981) 1.79
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. J Biol Chem (1999) 1.77
Intracellular calcium measurements by 19F NMR of fluorine-labeled chelators. Proc Natl Acad Sci U S A (1983) 1.77
Sorting and transport of alpha herpesviruses in axons. Traffic (2001) 1.76
Development of a fluorogenic RT-PCR assay (TaqMan) for the detection of Hendra virus. J Virol Methods (2001) 1.74
Reversible lipid titrations of the activity of pure adenosine triphosphatase-lipid complexes. Biochemistry (1974) 1.73
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases. The involvement of COOH-terminal docking sites and NH2-terminal UCR regions. J Biol Chem (2000) 1.68
Degenerate perturbations of protein structure as the mechanism of anaesthetic action. Nature (1979) 1.68
A calcium hypothesis for the control of cell growth. Biochem Soc Symp (1980) 1.66
Purification and properties of the insulin-stimulated cyclic AMP phosphodiesterase from rat liver plasma membranes. Biochem J (1981) 1.58
Electrical injuries in a pediatric emergency department. Ann Emerg Med (1995) 1.55
Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes. Biochem J (1983) 1.53
Intracellular pH of stimulated thymocytes measured with a new fluorescent indicator. J Biol Chem (1983) 1.53
Triggering of lymphocyte capping appears not to require changes in potential or ion fluxes across the plasma membrane. Biochim Biophys Acta (1980) 1.52
The information-loss model: a mathematical theory of age-related cognitive slowing. Psychol Rev (1990) 1.52
Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene. Biochem J (1997) 1.51
Changes in the form of Arrhenius plots of the activity of glucagon-stimulated adenylate cyclase and other hamster liver plasma-membrane enzymes occurring on hibernation. Biochem J (1978) 1.51
Clusters in lipid bilayers and the interpretation of thermal effects in biological membranes. Biochemistry (1974) 1.50
The interaction of paramagnetic ions and spin labels with lecithin bilayers. Biochim Biophys Acta (1973) 1.49
Survival and development in culture of dissociated parasympathetic neurons from ciliary ganglia. Dev Biol (1976) 1.49
The increase in bilayer fluidity of rat liver plasma membranes achieved by the local anesthetic benzyl alcohol affects the activity of intrinsic membrane enzymes. J Biol Chem (1980) 1.49
Sensitive assay, based on hydroxy fatty acids from lipopolysaccharide lipid A, for Gram-negative bacteria in sediments. Appl Environ Microbiol (1982) 1.48
The nature of the electrophoretically separable multiple forms of rat liver monoamine oxidase. Biochem J (1973) 1.47
cAMP-specific phosphodiesterase HSPDE4D3 mutants which mimic activation and changes in rolipram inhibition triggered by protein kinase A phosphorylation of Ser-54: generation of a molecular model. Biochem J (1998) 1.46
Exchange of partners in glucagon receptor-adenylate cyclase complexes. Physical evidence for the independent, mobile receptor model. Biochim Biophys Acta (1977) 1.46
The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go. FEBS Lett (1987) 1.46
Genetic covariance among measures of information processing speed, working memory, and IQ. Behav Genet (2001) 1.41