Published in JPEN J Parenter Enteral Nutr on November 19, 1986
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A failed assay opened a new door in growth hormone research. Endocrinology (1992) 2.69
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Measurement of "true" glucose production rates in infancy and childhood with 6,6-dideuteroglucose. Diabetes (1977) 2.02
Measurement of leucine metabolism in man from a primed, continuous infusion of L-[1-3C]leucine. Am J Physiol (1980) 2.01
Alanine and glutamine synthesis and release from skeletal muscle. I. Glycolysis and amino acid release. J Biol Chem (1976) 1.87
Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock. Crit Care Med (2000) 1.85
Insulin-mediated reduction of whole body protein breakdown. Dose-response effects on leucine metabolism in postabsorptive men. J Clin Invest (1985) 1.85
Identification of type I diabetic patients at increased risk for hypoglycemia during intensive therapy. N Engl J Med (1983) 1.83
Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and women. Am J Physiol (1993) 1.81
Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon. N Engl J Med (1975) 1.80
Contribution of liver and skeletal muscle to alanine and lactate metabolism in humans. Am J Physiol (1990) 1.71
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Relationship of plasma leucine and alpha-ketoisocaproate during a L-[1-13C]leucine infusion in man: a method for measuring human intracellular leucine tracer enrichment. Metabolism (1982) 1.65
A theoretical basis for increasing current estimates of the amino acid requirements in adult man, with experimental support. Am J Clin Nutr (1989) 1.63
Alanine and glutamine synthesis and release from skeletal muscle. II. The precursor role of amino acids in alanine and glutamine synthesis. J Biol Chem (1976) 1.59
Mechanism of increased gluconeogenesis in noninsulin-dependent diabetes mellitus. Role of alterations in systemic, hepatic, and muscle lactate and alanine metabolism. J Clin Invest (1990) 1.55
Role of specific glycopeptides of human serum lipoproteins in the activation of lipoprotein lipase. Circ Res (1970) 1.52
Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis. Crit Care Med (2000) 1.48
Duplicate publication and related problems. Pediatrics (1990) 1.46
Inhibition of NO synthesis in septic shock. Lancet (1992) 1.46
Plasma glucose kinetics during exercise in subjects with high and low lactate thresholds. J Appl Physiol (1985) (1992) 1.46
Glucose requirements following burn injury. Parameters of optimal glucose infusion and possible hepatic and respiratory abnormalities following excessive glucose intake. Ann Surg (1979) 1.45
Dissociation of effects of insulin and contraction on glucose transport in rat epitrochlearis muscle. Am J Physiol (1985) 1.42
Whole-body leucine and lysine metabolism: response to dietary protein intake in young men. Am J Physiol (1981) 1.41
In-vivo measurement of glucose and alanine metabolism with stable isotopic tracers. Diabetes (1977) 1.41
The conversion of phenylalanine to tyrosine in man. Direct measurement by continuous intravenous tracer infusions of L-[ring-2H5]phenylalanine and L-[1-13C] tyrosine in the postabsorptive state. Metabolism (1982) 1.38
Glutamine and glutamate kinetics in humans. Am J Physiol (1986) 1.33
Effect of growth hormone and resistance exercise on muscle growth in young men. Am J Physiol (1992) 1.33
Alanine and glutamine synthesis and release from skeletal muscle. IV. beta-Adrenergic inhibition of amino acid release. J Biol Chem (1976) 1.33
Epitrochlearis muscle. I. Mechanical performance, energetics, and fiber composition. Am J Physiol (1980) 1.32
A microfluorometric enzymatic assay for the determination of alanine and pyruvate in plasma and tissues. J Lab Clin Med (1972) 1.32
Measurement of muscle protein fractional synthetic rate by capillary gas chromatography/combustion isotope ratio mass spectrometry. Biol Mass Spectrom (1992) 1.28
Hypoglycemia in infancy and childhood. II. J Pediatr (1973) 1.28
Role of arginine in health and in renal disease. Am J Physiol (1994) 1.26
Hypoglycemia in infancy and childhood. I. J Pediatr (1973) 1.24
Epinephrine plasma thresholds for lipolytic effects in man: measurements of fatty acid transport with [l-13C]palmitic acid. J Clin Invest (1981) 1.24
Physiological hypercortisolemia increases proteolysis, glutamine, and alanine production. Am J Physiol (1988) 1.22
Hypoglycemia in compensated chronic renal insufficiency. Substrate limitation of gluconeogenesis. Diabetes (1974) 1.21
Alanine and glutamine synthesis and release from skeletal muscle. III. Dietary and hormonal regulation. J Biol Chem (1976) 1.19
Increased gluconeogenic substrates in the small-for-gestational-age infant. N Engl J Med (1974) 1.14
Effects of physiologic levels of glucagon and growth hormone on human carbohydrate and lipid metabolism. Studies involving administration of exogenous hormone during suppression of endogenous hormone secretion with somatostatin. J Clin Invest (1976) 1.13
Hypoglycemia, hepatic dysfunction, muscle weakness, cardiomyopathy, free carnitine deficiency and long-chain acylcarnitine excess responsive to medium chain triglyceride diet. Pediatr Res (1983) 1.13
Effect of growth hormone and resistance exercise on muscle growth and strength in older men. Am J Physiol (1995) 1.12
Role of apoptosis in Pseudomonas aeruginosa pneumonia. Science (2001) 1.11
Activation of lipoprotein lipase by lipoprotein fractions of human serum. J Lipid Res (1970) 1.09
An unusual cause of tetraplegia in a dog. Can Vet J (1967) 1.09
Ketotic hypoglycemia: an amino acid substrate limited disorder. J Clin Endocrinol Metab (1974) 1.08
Undermodeling affects minimal model indexes: insights from a two-compartment model. Am J Physiol (1999) 1.08
Glucose and insulin effects on the novo amino acid synthesis in young men: studies with stable isotope labeled alanine, glycine, leucine, and lysine. Metabolism (1982) 1.07
Whole body de novo amino acid synthesis in type I (insulin-dependent) diabetes studied with stable isotope-labeled leucine, alanine, and glycine. Diabetes (1985) 1.07
Models to interpret kinetic data in stable isotope tracer studies. Am J Physiol (1987) 1.07
Role of counterregulatory hormones in the catabolic response to stress. J Clin Invest (1984) 1.06
Glucose production, gluconeogenesis, and insulin sensitivity in children and adolescents: an evaluation of their reproducibility. Pediatr Res (2001) 1.05
The stimulus-secretion coupling of amino acid-induced insulin release. Metabolic response of pancreatic islets of L-glutamine and L-leucine. J Biol Chem (1982) 1.05
Duplicate publication and related problems. Arch Dis Child (1990) 1.05
Effect of endurance training on plasma free fatty acid turnover and oxidation during exercise. Am J Physiol (1993) 1.04
Regulation of leucine metabolism in man: a stable isotope study. Science (1981) 1.04
Inducible nitric oxide synthase (iNOS) gene deficiency increases the mortality of sepsis in mice. Surgery (1999) 1.04
Increased intracellular Ca2+: a critical link in the pathophysiology of sepsis? Proc Natl Acad Sci U S A (1993) 1.04
Endurance training decreases plasma glucose turnover and oxidation during moderate-intensity exercise in men. J Appl Physiol (1985) (1990) 1.04
The alpha-keto acids of branched-chain amino acids: simplified derivatization for physiological samples and complete separation as quinoxalinols by packed column gas chromatography. Anal Biochem (1980) 1.03
Quantitative analysis of regenerating and degenerating areas within the lobule of the carbon tetrachloride-injured liver. Arch Biochem Biophys (1965) 1.02
Glutamine: a major gluconeogenic precursor and vehicle for interorgan carbon transport in man. J Clin Invest (1995) 1.01
Early effects of anti-insulin serum on hepatic metabolism of plasma free fatty acids in dogs. Diabetes (1972) 1.01
A model to measure insulin effects on glucose transport and phosphorylation in muscle: a three-tracer study. Am J Physiol (1996) 1.01
Alanine kinetics in humans: influence of different isotopic tracers. Am J Physiol (1984) 1.00
Determination of stable isotopic enrichment in individual plasma amino acids by chemical ionization mass spectrometry. Anal Chem (1979) 1.00
Cytokine blockade in sepsis--Are two better than one? Crit Care Med (2001) 0.99
Gluconeogenesis in very low birth weight infants receiving total parenteral nutrition. Diabetes (1999) 0.99
Quantitative aspects of glucose production and metabolism in healthy elderly subjects. Diabetes (1982) 0.99
Dantrolene ameliorates the metabolic hallmarks of sepsis in rats and improves survival in a mouse model of endotoxemia. Proc Natl Acad Sci U S A (1994) 0.98
Hypothalamic stimulation of growth hormone and thyrotropin lease in vitro and pituitary 3'5'-adenosine cyclic monophosphate. Endocrinology (1970) 0.98
Estimation of glucose-alanine-lactate-glutamine cycles in postabsorptive humans: role of skeletal muscle. Am J Physiol (1995) 0.98
Measurement of urea kinetics in humans: a validation of stable isotope tracer methods. Am J Physiol (1984) 0.98
Determination of kinetic parameters of apolipoprotein B metabolism using amino acids labeled with stable isotopes. J Lipid Res (1991) 0.97
Effect of intravenous amino acids on protein metabolism of preterm infants during the first three days of life. Pediatr Res (1993) 0.97
Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazole. Am J Physiol (1991) 0.96
Ketone body transport in the human neonate and infant. J Clin Invest (1986) 0.96
Mechanisms of cell injury and death. Br J Anaesth (1996) 0.96
The nutritional phenotype in the age of metabolomics. J Nutr (2005) 0.96
Epitrochlearis muscle. II. Metabolic effects of contraction and catecholamines. Am J Physiol (1980) 0.95
Short-term growth hormone treatment does not increase muscle protein synthesis in experienced weight lifters. J Appl Physiol (1985) (1993) 0.95
Molecular biology of multiple organ dysfunction syndrome: injury, adaptation, and apoptosis. Surg Infect (Larchmt) (2000) 0.94
Effects of reduced renal mass and dietary protein intake on amino acid release and glucose uptake by rat muscle in vitro. J Clin Invest (1979) 0.94
An unusual congenital cardiac defect in a dog. Can Vet J (1966) 0.94
Calcium: a regulator of the inflammatory response in endotoxemia and sepsis. New Horiz (1996) 0.94
Effects of protein restriction and acute refeeding on leucine and lysine kinetics in young men. Am J Physiol (1993) 0.94
Bioavailability of dietary urea nitrogen in the breast-fed infant. J Pediatr (1988) 0.93
Resistance exercise and growth hormone administration in older men: effects on insulin sensitivity and secretion during a stable-label intravenous glucose tolerance test. Metabolism (1996) 0.92
Leucine metabolism in aging humans: effect of insulin and substrate availability. Am J Physiol (1989) 0.92