Published in Biochim Biophys Acta on March 28, 1979
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Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell (2001) 4.73
Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14. Mol Cell (2000) 4.05
Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction. Mol Cell Biol (1999) 3.90
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Functional similarity and physical association between GCN5 and ADA2: putative transcriptional adaptors. EMBO J (1994) 3.00
Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo. Genes Dev (1998) 2.76
Snf1--a histone kinase that works in concert with the histone acetyltransferase Gcn5 to regulate transcription. Science (2001) 2.58
Histone acetyltransferase activity and interaction with ADA2 are critical for GCN5 function in vivo. EMBO J (1997) 2.58
Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Nature (1999) 2.50
Preparation of cDNA and the generation of cDNA libraries: overview. Methods Enzymol (1987) 2.40
Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein. J Biol Chem (1995) 2.37
Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5. Mol Cell Biol (1996) 2.30
The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes. Trends Cell Biol (1998) 2.28
Catalytic mechanism and function of invariant glutamic acid 173 from the histone acetyltransferase GCN5 transcriptional coactivator. J Biol Chem (1999) 2.13
Structural and functional analysis of yeast putative adaptors. Evidence for an adaptor complex in vivo. J Biol Chem (1996) 2.01
Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters. Mol Cell Biol (2000) 2.00
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Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator. Proc Natl Acad Sci U S A (1999) 1.99
Gene expression during reactivation of herpes simplex virus type 1 from latency in the peripheral nervous system is different from that during lytic infection of tissue cultures. J Virol (1997) 1.86
Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation. Mol Cell Biol (1997) 1.85
During lytic infection herpes simplex virus type 1 is associated with histones bearing modifications that correlate with active transcription. J Virol (2004) 1.84
Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases. Mol Cell (2000) 1.80
Spectrin deficient inherited hemolytic anemias in the mouse: characterization by spectrin synthesis and mRNA activity in reticulocytes. Cell (1984) 1.77
Differential activation of RNA polymerase III-transcribed genes by the polyomavirus enhancer and the adenovirus E1A gene products. Nucleic Acids Res (1985) 1.72
Absence of Gcn5 HAT activity defines a novel state in the opening of chromatin at the PHO5 promoter in yeast. Mol Cell (1998) 1.71
Two tandem and independent sub-activation domains in the amino terminus of p53 require the adaptor complex for activity. Oncogene (1997) 1.70
CREB-binding protein and p300/CBP-associated factor are transcriptional coactivators of the p53 tumor suppressor protein. Cancer Res (1997) 1.70
Ribonuclease H activities associated with viral reverse transcriptases are endonucleases. Proc Natl Acad Sci U S A (1989) 1.67
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A conserved motif present in a class of helix-loop-helix proteins activates transcription by direct recruitment of the SAGA complex. Mol Cell (1999) 1.55
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Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol Cell Biol (1998) 1.50
Nucleotides in the polyomavirus enhancer that control viral transcription and DNA replication. Mol Cell Biol (1987) 1.48
Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members. Nucleic Acids Res (1998) 1.47
The human prothymosin alpha gene is polymorphic and induced upon growth stimulation: evidence using a cloned cDNA. Proc Natl Acad Sci U S A (1986) 1.43
Molecular hybridization of immobilized nucleic acids: theoretical concepts and practical considerations. Methods Enzymol (1987) 1.43
Crystal structure of the histone acetyltransferase domain of the human PCAF transcriptional regulator bound to coenzyme A. EMBO J (1999) 1.39
Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. J Cell Biol (1991) 1.32
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Small, membrane-bound, alternatively spliced forms of ankyrin 1 associated with the sarcoplasmic reticulum of mammalian skeletal muscle. J Cell Biol (1997) 1.27
Ankyrin and the hemolytic anemia mutation, nb, map to mouse chromosome 8: presence of the nb allele is associated with a truncated erythrocyte ankyrin. Proc Natl Acad Sci U S A (1990) 1.26
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Structure and function of bromodomains in chromatin-regulating complexes. Gene (2001) 1.15
Screening colonies or plaques with radioactive nucleic acid probes. Methods Enzymol (1987) 1.13
Very short-lived and stable mRNAs from resting human lymphocytes. Proc Natl Acad Sci U S A (1975) 1.13
Homopolymeric tailing. Methods Enzymol (1987) 1.12
Isolation and partial sequencing of the human prothymosin alpha gene family. Evidence against export of the gene products. J Biol Chem (1989) 1.11
GCN5 and ADA adaptor proteins regulate triiodothyronine/GRIP1 and SRC-1 coactivator-dependent gene activation by the human thyroid hormone receptor. Mol Endocrinol (2000) 1.11
Activation of chromosomal DNA replication in Saccharomyces cerevisiae by acidic transcriptional activation domains. Mol Cell Biol (1998) 1.08
Enhanced sensitivity to neutralizing antibodies in a variant of equine infectious anemia virus is linked to amino acid substitutions in the surface unit envelope glycoprotein. J Virol (1995) 1.07
Prothymosin alpha antisense oligomers inhibit myeloma cell division. Proc Natl Acad Sci U S A (1991) 1.07
Quantifying 32P-labeled and unlabeled nucleic acids. Methods Enzymol (1987) 1.06
Remarkable homology among the internal repeats of erythroid and nonerythroid spectrin. Proc Natl Acad Sci U S A (1985) 1.06
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Isolation of RNA. Methods Enzymol (1989) 1.04
Nuclear targeting of prothymosin alpha. J Biol Chem (1991) 1.01
Identification and analysis of native nucleosomal histone acetyltransferase complexes. Methods Mol Biol (1999) 1.00
Interplay between chromatin modifying and remodeling complexes in transcriptional regulation. Crit Rev Eukaryot Gene Expr (1999) 0.99
Effect of ribonucleoside-vanadyl complexes on enzyme-catalyzed reactions central to recombinant deoxyribonucleic acid technology. Biochemistry (1982) 0.98
Changing patterns in cytoskeletal mRNA expression and protein synthesis during murine erythropoiesis in vivo. Proc Natl Acad Sci U S A (1992) 0.95
Reverse transcriptase from human immunodeficiency virus: a single template-primer binding site serves two physically separable catalytic functions. Biochemistry (1991) 0.95
Fetal compensation of the hemolytic anemia in mice homozygous for the normoblastosis (nb) mutation. Blood (1992) 0.93
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GAG triplets as splice acceptors of last resort. An unusual form of alternative splicing in prothymosin alpha pre-mRNA. J Mol Biol (1993) 0.91
Preparation of interferon messenger RNAs with the use of ribonucleoside--vanadyl complexes. Methods Enzymol (1981) 0.90
Gene regulation. Local or global? Nature (2000) 0.90
Lymphocytes as resting cells. Methods Enzymol (1979) 0.90
Histone H2B ubiquitylation and deubiquitylation in genomic regulation. Cold Spring Harb Symp Quant Biol (2004) 0.89
Characterization of interferon messenger RNA synthesis in Namalva cells. J Biol Chem (1980) 0.89
Preparation and characterization of RNA: overview. Methods Enzymol (1987) 0.88
Free ribosomes in physiologically nondividing cells. Human peripheral lymphocytes. J Biol Chem (1976) 0.88
The human transcriptional adaptor genes TADA2L and GCN5L2 colocalize to chromosome 17q12-q21 and display a similar tissue expression pattern. Genomics (1997) 0.87
Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice. Blood (1993) 0.86
The human prothymosin alpha gene family contains several processed pseudogenes lacking deleterious lesions. Genomics (1992) 0.86
Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model. Cell Death Differ (2013) 0.86
Murine erythrocyte ankyrin cDNA: highly conserved regions of the regulatory domain. Mamm Genome (1992) 0.86
Purification of large double-stranded cDNA fragments. Methods Enzymol (1987) 0.85
Turnover of the acyl phosphates of human and murine prothymosin alpha in vivo. J Biol Chem (1997) 0.84
Histone post-translational modifications regulate transcription and silent chromatin in Saccharomyces cerevisiae. Ernst Schering Res Found Workshop (2006) 0.83
Functional discontinuities in prothymosin alpha caused by caspase cleavage in apoptotic cells. J Cell Physiol (2000) 0.82
The acidic transcriptional activation domains of herpes virus VP16 and yeast HAP4 have different co-factor requirements. Gene (1995) 0.82
The use of Cerenkov radiation for monitoring reactions performed in minute volumes: examples from recombinant DNA technology. Anal Biochem (1984) 0.82
A micromethod for measuring the molar concentration of polyadenylated RNA in the presence of ribosomal RNA. Anal Biochem (1986) 0.82
Prothymosin alpha in vivo contains phosphorylated glutamic acid residues. J Biol Chem (1997) 0.81
Direct mapping of rare messenger RNAs by means of oligomer-directed ribonuclease H cleavage. Anal Biochem (1987) 0.81
Human prothymosin alpha: purification of a highly acidic nuclear protein by means of a phenol extraction. Protein Expr Purif (1990) 0.81