Published in Infect Immun on September 01, 1988
Alpha-toxin of Staphylococcus aureus. Microbiol Rev (1991) 6.14
Staphylococcus aureus hemolysins, bi-component leukocidins, and cytolytic peptides: a redundant arsenal of membrane-damaging virulence factors? Front Cell Infect Microbiol (2012) 1.84
Effects of subinhibitory concentrations of antibiotics on alpha-toxin (hla) gene expression of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates. Antimicrob Agents Chemother (1998) 1.70
Human endothelial cell activation and mediator release in response to Listeria monocytogenes virulence factors. Infect Immun (2001) 1.16
Effects of Escherichia coli hemolysin on endothelial cell function. Infect Immun (1990) 1.16
Programmed cellular necrosis mediated by the pore-forming alpha-toxin from Clostridium septicum. PLoS Pathog (2009) 1.09
Pore-forming bacterial toxins potently induce release of nitric oxide in porcine endothelial cells. J Exp Med (1993) 0.98
Leukotriene and hydroxyeicosatetraenoic acid generation elicited by low doses of Escherichia coli hemolysin in rabbit lungs. Infect Immun (1990) 0.96
Staphylococcus aureus α-toxin triggers the synthesis of B-cell lymphoma 3 by human platelets. Toxins (Basel) (2011) 0.79
Inflammatory lipid mediator generation elicited by viable hemolysin-forming Escherichia coli in lung vasculature. J Exp Med (1990) 0.79
Staphylococcal alpha toxin: a study with chronically instrumented awake sheep. Infect Immun (1992) 0.78
Inositol trisphosphate and diacylglycerol: two interacting second messengers. Annu Rev Biochem (1987) 12.04
Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator. J Cell Biol (1982) 11.87
Mechanism of lymphocyte-mediated cytotoxicity. Annu Rev Immunol (1985) 4.19
On the mechanism of membrane damage by Staphylococcus aureus alpha-toxin. J Cell Biol (1981) 4.06
Is cytosolic ionized calcium regulating neutrophil activation? Science (1983) 3.97
Escherichia coli hemolysin may damage target cell membranes by generating transmembrane pores. Infect Immun (1986) 3.94
Mechanism of membrane damage by streptolysin-O. Infect Immun (1985) 3.26
Staphylococcal alpha-toxin: oligomerization of hydrophilic monomers to form amphiphilic hexamers induced through contact with deoxycholate detergent micelles. Proc Natl Acad Sci U S A (1981) 2.38
Damage to mammalian cells by proteins that form transmembrane pores. Rev Physiol Biochem Pharmacol (1987) 2.36
The role of protein kinase C in transmembrane signalling. Annu Rev Cell Biol (1986) 2.29
Damage to cell membranes by pore-forming bacterial cytolysins. Prog Allergy (1988) 2.23
Ca2+ homeostasis in permeabilized human neutrophils. Characterization of Ca2+-sequestering pools and the action of inositol 1,4,5-triphosphate. J Biol Chem (1984) 2.20
Correlation between toxin binding and hemolytic activity in membrane damage by staphylococcal alpha-toxin. Infect Immun (1984) 2.01
Staphylococcal alpha-toxin-induced PGI2 production in endothelial cells: role of calcium. Am J Physiol (1985) 1.57
Calcium fluxes and calcium buffering in human neutrophils. J Biol Chem (1986) 1.52
Characterization of fMet-Leu-Phe receptor-mediated Ca2+ influx across the plasma membrane of human neutrophils. Mol Pharmacol (1986) 1.49
The recovery of human polymorphonuclear leucocytes from sublytic complement attack is mediated by changes in intracellular free calcium. Biochem J (1985) 1.49
Staphylococcal alpha-toxin elicits hypertension in isolated rabbit lungs. Evidence for thromboxane formation and the role of extracellular calcium. J Clin Invest (1984) 1.43
Calcium channel ligands. Annu Rev Pharmacol Toxicol (1987) 1.43
Minimal requirements for exocytosis. A study using PC 12 cells permeabilized with staphylococcal alpha-toxin. J Biol Chem (1985) 1.40
Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin. Infect Immun (1987) 1.30
Signal transduction and ligand-receptor dynamics in the human neutrophil. Transient responses and occupancy-response relations at the formyl peptide receptor. J Biol Chem (1985) 1.27
Involvement of membrane calcium in the response of rabbit neutrophils to chemotactic factors as evidenced by the fluorescence of chlorotetracycline. J Cell Biol (1979) 1.20
Noncytolytic terminal complement complexes may serve as calcium gates to elicit leukotriene B4 generation in human polymorphonuclear leukocytes. J Immunol (1986) 1.13
Monitoring of cytosolic free Ca2+ in C5a-stimulated neutrophils: loss of receptor-modulated Ca2+ stores and Ca2+ uptake in granule-free cytoplasts. Proc Natl Acad Sci U S A (1984) 1.08
Pseudomonas aeruginosa cytotoxin stimulates prostacyclin production in cultured pulmonary artery endothelial cells: membrane attack and calcium influx. J Cell Physiol (1985) 1.06
Ionic channels in leukocytes. J Leukoc Biol (1986) 1.00
Quantitative analysis of the binding and oligomerization of staphylococcal alpha-toxin in target erythrocyte membranes. Infect Immun (1987) 0.99
Quantitation of monomeric and oligomeric forms of membrane-bound staphylococcal alpha-toxin by enzyme-linked immunosorbent assay with a neutralizing monoclonal antibody. Infect Immun (1987) 0.99
Inhibition by verapamil of neutrophil responses to formylmethionylleucylphenylalanine and phorbol myristate acetate. Mechanisms involving Ca2+ changes, cyclic AMP and protein kinase C. Biochim Biophys Acta (1985) 0.97
Complement complex C5b-8 induces PGI2 formation in cultured endothelial cells. Am J Physiol (1987) 0.94
Cytosolic free calcium changes induced by chemotactic peptide in neutrophils from patients with chronic granulomatous disease. Blood (1984) 0.89
Metabolic requirements for maintenance of the chlortetracycline-labeled pool of membrane-bound calcium in human neutrophils. J Cell Physiol (1983) 0.80