Published in Front Cell Infect Microbiol on February 16, 2012
Role of pore-forming toxins in bacterial infectious diseases. Microbiol Mol Biol Rev (2013) 1.91
Cytotoxic Virulence Predicts Mortality in Nosocomial Pneumonia Due to Methicillin-Resistant Staphylococcus aureus. J Infect Dis (2014) 1.59
Staphylococcus aureus LukAB cytotoxin kills human neutrophils by targeting the CD11b subunit of the integrin Mac-1. Proc Natl Acad Sci U S A (2013) 1.45
Staphylococcus aureus Targets the Duffy Antigen Receptor for Chemokines (DARC) to Lyse Erythrocytes. Cell Host Microbe (2015) 1.45
Staphylococcus aureus elaborates leukocidin AB to mediate escape from within human neutrophils. Infect Immun (2013) 1.37
The bicomponent pore-forming leucocidins of Staphylococcus aureus. Microbiol Mol Biol Rev (2014) 1.32
PSMs of hypervirulent Staphylococcus aureus act as intracellular toxins that kill infected osteoblasts. PLoS One (2013) 1.26
Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids. Trends Microbiol (2013) 1.19
Toxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage. PLoS Pathog (2015) 1.11
The staphylococcal toxins γ-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors. Nat Commun (2014) 1.11
Five birds, one stone: neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody. MAbs (2015) 1.06
Staphylococcus aureus leukotoxin GH promotes formation of neutrophil extracellular traps. J Immunol (2013) 1.05
Autophagy mediates tolerance to Staphylococcus aureus alpha-toxin. Cell Host Microbe (2015) 1.04
Staphylococcal superantigens interact with multiple host receptors to cause serious diseases. Immunol Res (2014) 0.95
Identification of a crucial residue required for Staphylococcus aureus LukAB cytotoxicity and receptor recognition. Infect Immun (2013) 0.93
Glycoepitopes of staphylococcal wall teichoic acid govern complement-mediated opsonophagocytosis via human serum antibody and mannose-binding lectin. J Biol Chem (2013) 0.92
Efficacy profile of a bivalent Staphylococcus aureus glycoconjugated vaccine in adults on hemodialysis: Phase III randomized study. Hum Vaccin Immunother (2015) 0.90
Children with invasive Staphylococcus aureus disease exhibit a potently neutralizing antibody response to the cytotoxin LukAB. Infect Immun (2013) 0.86
High-resolution transcriptomic analysis of the adaptive response of Staphylococcus aureus during acute and chronic phases of osteomyelitis. MBio (2014) 0.85
Staphylococcal bicomponent pore-forming toxins: targets for prophylaxis and immunotherapy. Toxins (Basel) (2014) 0.85
Structure-function analysis of heterodimer formation, oligomerization, and receptor binding of the Staphylococcus aureus bi-component toxin LukGH. J Biol Chem (2014) 0.84
Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin. Antimicrob Agents Chemother (2016) 0.83
Bovine Staphylococcus aureus Secretes the Leukocidin LukMF' To Kill Migrating Neutrophils through CCR1. MBio (2015) 0.83
Cyclodextrin derivatives as anti-infectives. Curr Opin Pharmacol (2013) 0.82
Staphylococcus aureus α-hemolysin promotes platelet-neutrophil aggregate formation. J Infect Dis (2013) 0.82
Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology. Dis Model Mech (2015) 0.82
The staphylococci and staphylococcal pathogenesis. Front Cell Infect Microbiol (2012) 0.82
Targeting Staphylococcus aureus Toxins: A Potential form of Anti-Virulence Therapy. Toxins (Basel) (2016) 0.81
Exploring the transcriptome of Staphylococcus aureus in its natural niche. Sci Rep (2016) 0.80
YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function. Chem Rev (2017) 0.79
Using functional genomics to decipher the complexity of microbial pathogenicity. Curr Genet (2016) 0.79
Direct, Specific and Rapid Detection of Staphylococcal Proteins and Exotoxins Using a Multiplex Antibody Microarray. PLoS One (2015) 0.79
Uncontrolled sepsis: a systematic review of translational immunology studies in intensive care medicine. Intensive Care Med Exp (2014) 0.79
Levels of alpha-toxin correlate with distinct phenotypic response profiles of blood mononuclear cells and with agr background of community-associated Staphylococcus aureus isolates. PLoS One (2014) 0.79
Crystal structures of the components of the Staphylococcus aureus leukotoxin ED. Acta Crystallogr D Struct Biol (2016) 0.78
Kineret®/IL-1ra blocks the IL-1/IL-8 inflammatory cascade during recombinant Panton Valentine Leukocidin-triggered pneumonia but not during S. aureus infection. PLoS One (2014) 0.78
Staphylococcus aureus β-Toxin Mutants Are Defective in Biofilm Ligase and Sphingomyelinase Activity, and Causation of Infective Endocarditis and Sepsis. Biochemistry (2016) 0.78
Staphylococcus aureus Coordinates Leukocidin Expression and Pathogenesis by Sensing Metabolic Fluxes via RpiRc. MBio (2016) 0.78
Leukocidins: staphylococcal bi-component pore-forming toxins find their receptors. Nat Rev Microbiol (2017) 0.78
Curcumin protects mice from Staphylococcus aureus pneumonia by interfering with the self-assembly process of α-hemolysin. Sci Rep (2016) 0.77
Genotypic and phenotypic analysis of clinical isolates of Staphylococcus aureus revealed production patterns and hemolytic potentials unlinked to gene profiles and source. BMC Microbiol (2016) 0.77
The levels of antibodies to Panton-Valentine leukocidin (PVL) vary with PVL prevalence along a north-to-south gradient. Eur J Clin Microbiol Infect Dis (2015) 0.77
IgG4 subclass-specific responses to Staphylococcus aureus antigens shed new light on host-pathogen interaction. Infect Immun (2014) 0.77
Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis. Front Cell Infect Microbiol (2015) 0.77
Host response to Staphylococcus aureus cytotoxins in children with cystic fibrosis. J Cyst Fibros (2016) 0.77
Separately or combined, LukG/LukH is functionally unique compared to other staphylococcal bicomponent leukotoxins. PLoS One (2014) 0.77
Mycobacterial ESX-1 secretion system mediates host cell lysis through bacterium contact-dependent gross membrane disruptions. Proc Natl Acad Sci U S A (2017) 0.76
Virulence Factors and Antibiotic Susceptibility of Staphylococcus aureus Isolates in Ready-to-Eat Foods: Detection of S. aureus Contamination and a High Prevalence of Virulence Genes. Int J Environ Res Public Health (2016) 0.76
In vitro selection of single-stranded DNA molecular recognition elements against S. aureus alpha toxin and sensitive detection in human serum. Int J Mol Sci (2015) 0.76
Staphylococcus aureus Toxins and Diabetic Foot Ulcers: Role in Pathogenesis and Interest in Diagnosis. Toxins (Basel) (2016) 0.76
First Staphylococcal Cassette Chromosome mec Containing a mecB-Carrying Gene Complex Independent of Transposon Tn6045 in a Macrococcus caseolyticus Isolate from a Canine Infection. Antimicrob Agents Chemother (2015) 0.76
Sequencing of bacterial genomes: principles and insights into pathogenesis and development of antibiotics. Genes (Basel) (2013) 0.76
Genomic Heterogeneity of Methicillin Resistant Staphylococcus aureus Associated with Variation in Severity of Illness among Children with Acute Hematogenous Osteomyelitis. PLoS One (2015) 0.76
Phenol-Soluble Modulins Contribute to Early Sepsis Dissemination Not Late Local USA300-Osteomyelitis Severity in Rabbits. PLoS One (2016) 0.75
Genotypic Diversity of Staphylococcus aureus α-Hemolysin Gene (hla) and Its Association with Clonal Background: Implications for Vaccine Development. PLoS One (2016) 0.75
A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains. Sci Rep (2016) 0.75
Host-inherent variability influences the transcriptional response of Staphylococcus aureus during in vivo infection. Nat Commun (2017) 0.75
Identification and Characterization of Staphylococcus aureus Strains with an Incomplete Hemolytic Phenotype. Front Cell Infect Microbiol (2016) 0.75
Molecular Characterization of Community Acquired Staphylococcus aureus Bacteremia in Young Children in Southern Mozambique, 2001-2009. Front Microbiol (2017) 0.75
Atypical sensors for direct and rapid neuronal detection of bacterial pathogens. Mol Brain (2016) 0.75
Targeting and inactivation of bacterial toxins by human defensins. Biol Chem (2017) 0.75
Superantigens of a superbug: Major culprits of Staphylococcus aureus disease? Virulence (2016) 0.75
Molecular Typing of Staphylococcus aureus Isolated from Patients with Autosomal Dominant Hyper IgE Syndrome. Pathogens (2017) 0.75
Man is the new mouse: Elective surgery as a key translational model for multi-organ dysfunction and sepsis. J Intensive Care Soc (2015) 0.75
Epidermal Growth Factor Receptor Signaling Enhances the Proinflammatory Effects of Staphylococcus aureus Gamma-Toxin on the Mucosa. Toxins (Basel) (2017) 0.75
Similar Clinical Severity and Outcomes for Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Pediatric Musculoskeletal Infections. Open Forum Infect Dis (2017) 0.75
Inhibiting Microbial Toxins Using Plant-Derived Compounds and Plant Extracts. Medicines (Basel) (2015) 0.75
Bacterial toxins: Offensive, defensive, or something else altogether? PLoS Pathog (2017) 0.75
Epic Immune Battles of History: Neutrophils vs. Staphylococcus aureus. Front Cell Infect Microbiol (2017) 0.75
Involvement of Panton-Valentine leukocidin-producing Staphylococcus aureus in primary skin infections and pneumonia. Clin Infect Dis (1999) 19.52
Cryopyrin activates the inflammasome in response to toxins and ATP. Nature (2006) 18.74
Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore. Science (1996) 16.69
Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol (2008) 16.65
Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus. Lancet (2006) 15.99
Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis (2003) 13.83
Association between Staphylococcus aureus strains carrying gene for Panton-Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet (2002) 10.26
Calcium oscillations increase the efficiency and specificity of gene expression. Nature (1998) 9.19
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med (2011) 8.00
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA. Nat Med (2007) 7.75
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ (2007) 7.74
Immune evasion by staphylococci. Nat Rev Microbiol (2005) 7.22
Staphylococcus aureus Panton-Valentine leukocidin causes necrotizing pneumonia. Science (2007) 7.06
Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B. Nature (1993) 6.75
Alpha-toxin of Staphylococcus aureus. Microbiol Rev (1991) 6.14
Poring over pores: alpha-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia. Nat Med (2007) 5.95
Panton-Valentine leukocidin is not a virulence determinant in murine models of community-associated methicillin-resistant Staphylococcus aureus disease. J Infect Dis (2008) 4.16
Global distribution of Panton-Valentine leukocidin--positive methicillin-resistant Staphylococcus aureus, 2006. Emerg Infect Dis (2007) 3.98
Evolution of virulence in epidemic community-associated methicillin-resistant Staphylococcus aureus. Proc Natl Acad Sci U S A (2009) 3.89
The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on beta-hemolysin-converting bacteriophages. J Bacteriol (2006) 3.50
Purification and properties of staphylococcal delta hemolysin. Infect Immun (1971) 3.19
A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice. Nat Med (2011) 3.17
Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus. Annu Rev Microbiol (2010) 3.12
Staphylococcus aureus panton-valentine leukocidin is a very potent cytotoxic factor for human neutrophils. PLoS Pathog (2010) 3.11
Survival of Staphylococcus aureus inside neutrophils contributes to infection. J Immunol (2000) 3.08
Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A (2010) 3.05
Endothelial cells are central orchestrators of cytokine amplification during influenza virus infection. Cell (2011) 3.03
Ionic channels formed by Staphylococcus aureus alpha-toxin: voltage-dependent inhibition by divalent and trivalent cations. J Membr Biol (1986) 2.82
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J (2005) 2.72
Phage conversion of Panton-Valentine leukocidin in Staphylococcus aureus: molecular analysis of a PVL-converting phage, phiSLT. Gene (2001) 2.67
Human formyl peptide receptor 2 senses highly pathogenic Staphylococcus aureus. Cell Host Microbe (2010) 2.64
Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells. Infect Immun (1998) 2.63
Contribution of Panton-Valentine leukocidin in community-associated methicillin-resistant Staphylococcus aureus pathogenesis. PLoS One (2008) 2.62
Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. PLoS One (2009) 2.60
Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus alpha-hemolysin-mediated cellular injury. Proc Natl Acad Sci U S A (2010) 2.59
Release of interleukin-1 beta associated with potent cytocidal action of staphylococcal alpha-toxin on human monocytes. Infect Immun (1989) 2.42
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo. J Immunol (2007) 2.32
Pro-inflammatory programmed cell death. Trends Microbiol (2001) 2.30
Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection. J Infect Dis (2011) 2.19
Panton-Valentine leukocidin genes are associated with enhanced inflammatory response and local disease in acute hematogenous Staphylococcus aureus osteomyelitis in children. Pediatrics (2006) 2.17
The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect (2008) 2.14
Selective antimicrobial action is provided by phenol-soluble modulins derived from Staphylococcus epidermidis, a normal resident of the skin. J Invest Dermatol (2010) 2.13
Signaling by ROS drives inflammasome activation. Eur J Immunol (2010) 2.13
Staphylococcal alpha-toxin kills human keratinocytes by permeabilizing the plasma membrane for monovalent ions. Infect Immun (1993) 2.09
Bacterial two-component and hetero-heptameric pore-forming cytolytic toxins: structures, pore-forming mechanism, and organization of the genes. Biosci Biotechnol Biochem (2004) 2.07
Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. Trends Immunol (2011) 2.05
Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B. EMBO J (1994) 2.03
Regulation of raft-dependent endocytosis. J Cell Mol Med (2007) 2.01
Staphylococcus epidermidis surfactant peptides promote biofilm maturation and dissemination of biofilm-associated infection in mice. J Clin Invest (2010) 2.00
Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel. Nat Struct Biol (1999) 1.99
Epithelial cells are sensitive detectors of bacterial pore-forming toxins. J Biol Chem (2006) 1.90
Identification of a novel Staphylococcus aureus two-component leukotoxin using cell surface proteomics. PLoS One (2010) 1.89
Mobile genetic element-encoded cytolysin connects virulence to methicillin resistance in MRSA. PLoS Pathog (2009) 1.89
High levels of antibody to panton-valentine leukocidin are not associated with resistance to Staphylococcus aureus-associated skin and soft-tissue infection. Clin Infect Dis (2010) 1.84
An inflammatory polypeptide complex from Staphylococcus epidermidis: isolation and characterization. J Exp Med (1999) 1.82
Characterization of a novel structural member, LukE-LukD, of the bi-component staphylococcal leucotoxins family. FEBS Lett (1998) 1.81
The hemolysins of Staphylococcus aureus. Bacteriol Rev (1975) 1.77
NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens. Semin Immunol (2009) 1.77
Staphylococcus aureus Panton-Valentine leukocidin contributes to inflammation and muscle tissue injury. PLoS One (2009) 1.74
Hyperproduction of alpha-toxin by Staphylococcus aureus results in paradoxically reduced virulence in experimental endocarditis: a host defense role for platelet microbicidal proteins. Infect Immun (1997) 1.72
Characterization of a new cytotoxin that contributes to Staphylococcus aureus pathogenesis. Mol Microbiol (2010) 1.71
alpha-Toxin is a mediator of Staphylococcus aureus-induced cell death and activates caspases via the intrinsic death pathway independently of death receptor signaling. J Cell Biol (2001) 1.67
Presence of genes encoding the panton-valentine leukocidin exotoxin is not the primary determinant of outcome in patients with complicated skin and skin structure infections due to methicillin-resistant Staphylococcus aureus: results of a multinational trial. J Clin Microbiol (2009) 1.64
Pediatric bone and joint infections caused by Panton-Valentine leukocidin-positive Staphylococcus aureus. Pediatr Infect Dis J (2007) 1.64
Staphylococcus aureus leucocidin ED contributes to systemic infection by targeting neutrophils and promoting bacterial growth in vivo. Mol Microbiol (2011) 1.64
Microarray based study on virulence-associated genes and resistance determinants of Staphylococcus aureus isolates from cattle. Vet Microbiol (2007) 1.64
Transmembrane beta-barrel of staphylococcal alpha-toxin forms in sensitive but not in resistant cells. Proc Natl Acad Sci U S A (1997) 1.58
Global repression of exotoxin synthesis by staphylococcal superantigens. Proc Natl Acad Sci U S A (2002) 1.57
A phospholipase in staphylococcal toxin which hydrolyses sphingomyelin. Nature (1963) 1.55
Effects of staphylococcal alpha-, beta-, delta-, and gamma-hemolysins on human diploid fibroblasts and HeLa cells: evaluation of a new quantitative as say for measuring cell damage. Infect Immun (1973) 1.54
Antimicrobial activity of community-associated methicillin-resistant Staphylococcus aureus is caused by phenol-soluble modulin derivatives. J Biol Chem (2011) 1.51
A history of Panton-Valentine leukocidin (PVL)-associated infection protects against death in PVL-associated pneumonia. Vaccine (2011) 1.48
Panton-valentine leukocidin enhances the severity of community-associated methicillin-resistant Staphylococcus aureus rabbit osteomyelitis. PLoS One (2009) 1.48
The structure of a Staphylococcus aureus leucocidin component (LukF-PV) reveals the fold of the water-soluble species of a family of transmembrane pore-forming toxins. Structure (1999) 1.45
Beta toxin catalyzes formation of nucleoprotein matrix in staphylococcal biofilms. Proc Natl Acad Sci U S A (2010) 1.44
Synergistic hemolytic activity of Staphylococcus lugdunensis is mediated by three peptides encoded by a non-agr genetic locus. Infect Immun (1997) 1.44
Activation of human effector cells by different bacterial toxins (leukocidin, alveolysin, and erythrogenic toxin A): generation of interleukin-8. Infect Immun (1994) 1.44
Structure and biological activities of beta toxin from Staphylococcus aureus. J Bacteriol (2007) 1.43
Assessment of the role of gamma-toxin in experimental endophthalmitis using a hlg-deficient mutant of Staphylococcus aureus. Microb Pathog (1998) 1.40
Evidence of an intracellular reservoir in the nasal mucosa of patients with recurrent Staphylococcus aureus rhinosinusitis. J Infect Dis (2005) 1.39
Structure, organization, and function of glycosphingolipids in membrane. Curr Opin Hematol (2003) 1.39
Crystal structure of leucotoxin S component: new insight into the Staphylococcal beta-barrel pore-forming toxins. J Biol Chem (2004) 1.38
Direct and synergistic hemolysis caused by Staphylococcus phenol-soluble modulins: implications for diagnosis and pathogenesis. Microbes Infect (2011) 1.37
Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence. PLoS Pathog (2011) 1.34
Flow cytometric determination of Panton-Valentine leucocidin S component binding. Infect Immun (2001) 1.34
Leukotriene B4 generation and DNA fragmentation induced by leukocidin from Staphylococcus aureus: protective role of granulocyte-macrophage colony-stimulating factor (GM-CSF) and G-CSF for human neutrophils. Infect Immun (1994) 1.32
Potentiation of epithelial innate host responses by intercellular communication. PLoS Pathog (2010) 1.31
Evidence that clustered phosphocholine head groups serve as sites for binding and assembly of an oligomeric protein pore. J Biol Chem (2006) 1.31
Neutrophil responses to staphylococcal pathogens and commensals via the formyl peptide receptor 2 relates to phenol-soluble modulin release and virulence. FASEB J (2010) 1.31
Expression of δ-toxin by Staphylococcus aureus mediates escape from phago-endosomes of human epithelial and endothelial cells in the presence of β-toxin. Cell Microbiol (2010) 1.31
Mechanism of leukotriene generation in polymorphonuclear leukocytes by staphylococcal alpha-toxin. Infect Immun (1987) 1.30
Regulatory mechanism and physiological role of cytosolic phospholipase A2. Biol Pharm Bull (2004) 1.30
Panton-valentine leukocidin genes in a phage-like particle isolated from mitomycin C-treated Staphylococcus aureus V8 (ATCC 49775). Biosci Biotechnol Biochem (1997) 1.28
Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses. Infect Immun (2001) 1.28
Proteomics uncovers extreme heterogeneity in the Staphylococcus aureus exoproteome due to genomic plasticity and variant gene regulation. Proteomics (2010) 1.27
Predominant Staphylococcus aureus isolated from antibiotic-associated diarrhea is clinically relevant and produces enterotoxin A and the bicomponent toxin LukE-lukD. J Clin Microbiol (1999) 1.26
Membrane-damaging action of staphylococcal alpha-toxin on phospholipid-cholesterol liposomes. Biochim Biophys Acta (1987) 1.26
Fixation and inactivation of staphylococcal leukocidin by phosphatidylcholine and ganglioside GM1 in rabbit polymorphonuclear leukocytes. Infect Immun (1980) 1.25
Panton-Valentine leukocidin does play a role in the early stage of Staphylococcus aureus skin infections: a rabbit model. PLoS One (2011) 1.22
Electrical stimulation of the anterior nucleus of thalamus for treatment of refractory epilepsy. Epilepsia (2010) 5.64
Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis. Proc Natl Acad Sci U S A (2010) 4.57
egc, a highly prevalent operon of enterotoxin gene, forms a putative nursery of superantigens in Staphylococcus aureus. J Immunol (2001) 4.36
Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin. Nat Immunol (2008) 4.08
In vivo negative selection screen identifies genes required for Francisella virulence. Proc Natl Acad Sci U S A (2007) 3.73
Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. J Bacteriol (2000) 3.70
The Panton-Valentine leukocidin vaccine protects mice against lung and skin infections caused by Staphylococcus aureus USA300. Clin Microbiol Infect (2008) 2.14
Emergence and spread in French hospitals of methicillin-resistant Staphylococcus aureus with increasing susceptibility to gentamicin and other antibiotics. J Clin Microbiol (1999) 2.12
Involvement of enterotoxins G and I in staphylococcal toxic shock syndrome and staphylococcal scarlet fever. J Clin Microbiol (1999) 2.08
The intracellular fate of Salmonella depends on the recruitment of kinesin. Science (2005) 1.92
Prevalence of agr specificity groups among Staphylococcus aureus strains colonizing children and their guardians. J Clin Microbiol (2003) 1.82
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow. J Exp Med (2014) 1.82
Contribution of flagellin pattern recognition to intestinal inflammation during Salmonella enterica serotype typhimurium infection. Infect Immun (2009) 1.79
Emergence of two populations of methicillin-resistant Staphylococcus aureus with distinct epidemiological, clinical and biological features, isolated from patients with community-acquired skin infections. Br J Dermatol (2006) 1.70
The staphylococcal toxin Panton-Valentine Leukocidin targets human C5a receptors. Cell Host Microbe (2013) 1.66
The serine-aspartate repeat (Sdr) protein family in Staphylococcus epidermidis. Microbiology (2000) 1.66
Role of superantigenic strains in the prognosis of community-acquired methicillin-susceptible Staphylococcus aureus bacteraemia. Clin Microbiol Infect (2007) 1.55
Comparative performances of six agglutination kits assessed by using typical and atypical strains of Staphylococcus aureus. J Clin Microbiol (1997) 1.44
Clotting activity in Staphylococcus schleiferi subspecies from human patients. J Clin Microbiol (1994) 1.42
The translocated Salmonella effector proteins SseF and SseG interact and are required to establish an intracellular replication niche. Infect Immun (2006) 1.39
Effect of antibiotics, alone and in combination, on Panton-Valentine leukocidin production by a Staphylococcus aureus reference strain. Clin Microbiol Infect (2008) 1.37
Incidence of Staphylococcus aureus with reduced susceptibility to glycopeptides in two French hospitals. Clin Microbiol Infect (2001) 1.28
Serum antibodies against Panton-Valentine leukocidin in a normal population and during Staphylococcus aureus infection. Clin Microbiol Infect (2009) 1.26
Panton-Valentine leukocidin is expressed at toxic levels in human skin abscesses. Clin Microbiol Infect (2008) 1.24
Francisella tularensis: activation of the inflammasome. Ann N Y Acad Sci (2007) 1.22
The association of stigma with self-management and perceptions of health care among adults with epilepsy. Epilepsy Behav (2003) 1.20
Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner. Cell Microbiol (2012) 1.17
Auditory efferents involved in speech-in-noise intelligibility. Neuroreport (1997) 1.11
High prevalence of superantigens associated with the egc locus in Staphylococcus aureus isolates from patients with atopic eczema. Eur J Clin Microbiol Infect Dis (2003) 1.10
Epidemiological data of staphylococcal scalded skin syndrome in France from 1997 to 2007 and microbiological characteristics of Staphylococcus aureus associated strains. Clin Microbiol Infect (2012) 1.08
[Severe staphylococcal pneumonia in children]. Arch Pediatr (2001) 1.07
Species identification of staphylococci by amplification and sequencing of the tuf gene compared to the gap gene and by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Eur J Clin Microbiol Infect Dis (2010) 1.05
High prevalence of methicillin-resistant Staphylococcus aureus clone ST80-IV in hospital and community settings in Algiers. Clin Microbiol Infect (2011) 1.04
Asparagine assimilation is critical for intracellular replication and dissemination of Francisella. Cell Microbiol (2013) 1.04
Analysis of superantigenic toxin Vbeta T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock. Clin Microbiol Infect (2008) 1.01
The virulence protein SopD2 regulates membrane dynamics of Salmonella-containing vacuoles. PLoS Pathog (2010) 1.00
Pragmatic management of Panton-Valentine leukocidin-associated staphylococcal diseases. Int J Antimicrob Agents (2011) 1.00
trans-complementation of a Staphylococcus aureus agr mutant by Staphylococcus lugdunensis agr RNAIII. J Bacteriol (1998) 1.00
One in five mortality in non-menstrual toxic shock syndrome versus no mortality in menstrual cases in a balanced French series of 55 cases. Eur J Clin Microbiol Infect Dis (2008) 0.98
Staphylococcus schleiferi subsp. schleiferi expresses a fibronectin-binding protein. Infect Immun (1999) 0.98
Methicillin resistance is not a predictor of severity in community-acquired Staphylococcus aureus necrotizing pneumonia--results of a prospective observational study. Clin Microbiol Infect (2012) 0.98
Acute postoperative endophthalmitis caused by Staphylococcus lugdunensis. J Clin Microbiol (2007) 0.95
Evaluation of a commercial test kit for rapid detection of Staphylococcus aureus in blood cultures. Eur J Clin Microbiol Infect Dis (1997) 0.95
Pathogenesis of adult-onset Still's disease: new insights from the juvenile counterpart. Immunol Res (2015) 0.91
Distribution of the exfoliative toxin D gene in clinical Staphylococcus aureus isolates in France. Clin Microbiol Infect (2006) 0.89
Psychosocial predictors of lifestyle management in adults with epilepsy. Epilepsy Behav (2008) 0.88
Building community participatory research coalitions from the ground up: the Philadelphia area research community coalition. Prog Community Health Partnersh (2009) 0.88
Genetic differences among Staphylococcus aureus isolates from dairy ruminant species: a single-dye DNA microarray approach. Vet Microbiol (2008) 0.87
Induction of protective antiviral cytotoxic T cells by a tubular structure capable of carrying large foreign sequences. Vaccine (2002) 0.87
Distribution of edin in Staphylococcus aureus isolated from diabetic foot ulcers. Clin Microbiol Infect (2012) 0.86
Selection of optimal programming contacts based on local field potential recordings from subthalamic nucleus in patients with Parkinson's disease. Neurosurgery (2010) 0.86
Use of computers and the Internet for health information by patients with epilepsy. Epilepsy Behav (2007) 0.86
Presence of the epidemic European fusidic acid-resistant impetigo clone (EEFIC) of Staphylococcus aureus in France. J Antimicrob Chemother (2008) 0.86
S1PR5 is pivotal for the homeostasis of patrolling monocytes. Eur J Immunol (2013) 0.84
Amytal interview using intravenous lorazepam in a patient with dissociative fugue. Gen Hosp Psychiatry (2006) 0.84
[Osteoarticular infections with staphylococcus aureus secreting Panton-Valentine leucocidin]. Arch Pediatr (2007) 0.83
[Bacterial meningitis in infants 1 to 8 weeks old]. Arch Pediatr (2000) 0.82
Inflammasome activation restricts Legionella pneumophila replication in primary microglial cells through flagellin detection. Glia (2013) 0.82
Impacts of enterotoxin gene cluster-encoded superantigens on local and systemic experimental Staphylococcus aureus infections. Eur J Clin Microbiol Infect Dis (2015) 0.81
Staphylococcal entertotoxins of the enterotoxin gene cluster (egcSEs) induce nitrous oxide- and cytokine dependent tumor cell apoptosis in a broad panel of human tumor cells. Front Cell Infect Microbiol (2013) 0.80
Present and future automation in bacteriology. Clin Microbiol Infect (2011) 0.80
Activation of human monocyte chemiluminescence response by acylpoly(1,3)galactosides derived from Klebsiella pneumoniae. J Leukoc Biol (1992) 0.80
ASC controls IFN-γ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicida. J Immunol (2013) 0.79
Role of acyl residues in polyclonal murine B cell activation by acylpoly(1,3)galactosides from Klebsiella pneumoniae. J Immunol (1993) 0.79
The epilepsy medication and treatment complexity index: reliability and validity testing. J Neurosci Nurs (2003) 0.79
Contribution of amoebic coculture to recovery of Legionella isolates from respiratory samples: prospective analysis over a period of 32 months. J Clin Microbiol (2012) 0.79
Comparison of Sofia Legionella FIA and BinaxNOW® Legionella urinary antigen card in two national reference centers. Eur J Clin Microbiol Infect Dis (2015) 0.79
[Menstrual staphylococcal toxic shock is still a reality]. Presse Med (2003) 0.78
Monocyte cytokine secretion induced by chemically-defined derivatives of Klebsiella pneumoniae. Clin Exp Immunol (1992) 0.78
Clinical manifestations and outcome of skin infections caused by the community-acquired methicillin-resistant Staphylococcus aureus clone ST80-IV. J Eur Acad Dermatol Venereol (2010) 0.77
What is the place of linezolid in the treatment of methicillin-resistant Staphylococcus aureus nosocomial pneumonia and complicated skin and soft tissue infections in Europe? Clin Microbiol Infect (2014) 0.77
The levels of antibodies to Panton-Valentine leukocidin (PVL) vary with PVL prevalence along a north-to-south gradient. Eur J Clin Microbiol Infect Dis (2015) 0.77
The complexity of treatments for persons with epilepsy. Epilepsy Behav (2005) 0.77
Legionellosis and lung abscesses: contribution of legionella quantitative real-time PCR to an adapted followup. Case Rep Infect Dis (2013) 0.76
[The inflammasomes: platforms of innate immunity]. Med Sci (Paris) (2013) 0.76
PCR-confirmed Legionella non-pneumophila meningoencephalitis. Med Mal Infect (2013) 0.76
In vivo and in vitro detection of a superantigenic toxin Vbeta signature in two forms of streptococcal toxic shock syndrome. Eur J Clin Microbiol Infect Dis (2008) 0.76
[A case of indigenous skin infection caused by methicillin-resistant Staphylococcus aureus USA300 in France]. Ann Dermatol Venereol (2009) 0.75
Current outbreak of Staphylococcus aureus. Clin Microbiol Infect (2012) 0.75
First report of the predominance of clonal complex 398 Staphylococcus aureus strains in osteomyelitis complicating diabetic foot ulcers: a national French study. Clin Microbiol Infect (2013) 0.75
[Cochlear implantation in children]. Arch Pediatr (2003) 0.75
Multiple neonatal staphylococcal cold abscesses of the large folds. J Eur Acad Dermatol Venereol (2006) 0.75
[Chryseobacterium indologenes bacteremia in a patient with systemic corticosteroid therapy]. Ann Fr Anesth Reanim (2007) 0.75
Exploring the time-frequency content of high frequency oscillations for automated identification of seizure onset zone in epilepsy. J Neural Eng (2016) 0.75
[Intrafamilial transmission of Staphylococcus aureus Panton-Valentine leukocidin responsible for two cases of neonatal necrotizing pneumonia]. Arch Pediatr (2011) 0.75
[Current problems posed by staphylococcal infections in pediatric patients]. Presse Med (2001) 0.75
New epidemiology of Staphylococcus aureus infections. Clin Microbiol Infect (2014) 0.75
[The epidemiology of toxemic infections caused by Staphylococcus aureus in an intensive care setting]. Ann Fr Anesth Reanim (2002) 0.75
[Necrotizing community-acquired pneumonia secondary to influenza a (H1N1) super-infected by an invasive group A streptococcus]. Med Mal Infect (2010) 0.75