Published in J Immunol on December 01, 1979
Increased number of circulating Leu 11+ (CD 16) large granular lymphocytes and decreased NK activity during human ageing. Clin Exp Immunol (1987) 1.28
Natural killer cells in intravenous drug abusers with lymphadenopathy syndrome. Clin Exp Immunol (1985) 1.24
High activity of N-alpha-benzyloxycarbonyl-L-lysine thiobenzyl ester serine esterase and cytolytic perforin in cloned cell lines is not demonstrable in in-vivo-induced cytotoxic effector cells. Proc Natl Acad Sci U S A (1987) 1.09
Immediate-early gene expression is sufficient for induction of natural killer cell-mediated lysis of herpes simplex virus type 1-infected fibroblasts. J Virol (1991) 1.04
Immune defects in families and patients with xeroderma pigmentosum and trichothiodystrophy. Clin Exp Immunol (1992) 0.98
Use of anti-HLA antibodies to mask major histocompatibility complex gene products on tumor cells can enhance susceptibility of these cells to lysis by natural killer cells. J Clin Invest (1989) 0.96
Immunology of tumor infiltrating lymphocytes. Ann Surg (1985) 0.94
Modulation of human natural killer cell activity by pharmacological mediators. Clin Exp Immunol (1983) 0.94
Decreased NK killing in patients with multiple sclerosis: an analysis on the level of the single effector cell in peripheral blood and cerebrospinal fluid in relation to the activity in the disease. Clin Exp Immunol (1982) 0.94
Age-associated impairment of murine natural killer activity. Proc Natl Acad Sci U S A (1983) 0.92
Natural killer cell recognition of target cells expressing different antigens of vesicular stomatitis virus. Proc Natl Acad Sci U S A (1985) 0.91
Interleukin 2 and stimulator lymphoblastoid cells will induce human thymocytes to bind and kill K562 targets. J Exp Med (1982) 0.91
Activation of human NKCC by moderate exercise: increased frequency of NK cells with enhanced capability of effector--target lytic interactions. Clin Exp Immunol (1981) 0.90
Defective postbinding lysis underlies the impaired natural killer activity in factor VIII-treated, human T lymphotropic virus type III seropositive hemophiliacs. J Clin Invest (1986) 0.89
Deficiency of active natural killer cells in the Chediak-Higashi syndrome. Localization of the defect using a single cell cytotoxicity assay. J Clin Invest (1982) 0.89
A surgically induced hypoxic environment causes changes in the metastatic behaviour of tumours in vitro. Clin Exp Metastasis (2006) 0.88
Natural killer cell function is not diminished in the healthy aged and is proportional to the number of NK cells in the peripheral blood. Immunology (1989) 0.87
Suppression of natural killer cell activity by adherent effusion cells of cancer patients. Suppression of motility, binding capacity and lethal hit of NK cells. Br J Cancer (1984) 0.86
A novel role for MHC class II antigens: evidence implicating a protective effect on tumour cells against cytotoxicity by NK and LAK cells. Immunology (1994) 0.84
The mechanism of T-cell mediated cytotoxicity. VIII. Zeiosis corresponds to irreversible phase (programming for lysis) in steps leading to lysis. Immunology (1981) 0.78
Recruitment of OKM1 staining lymphocytes with selective binding to K-562 tumour targets by interferon. Clin Exp Immunol (1983) 0.78
In vitro effects of human lipoproteins on the immune system in healthy donors: inhibition of plaque forming cell generation and decreased frequency of NK cells. Clin Exp Immunol (1984) 0.77
C-reactive protein is involved in natural killer cell-mediated lysis but does not mediate effector-target cell recognition. Immunology (1987) 0.77
Natural killing and growth inhibition of K562 cells by subpopulations of mononuclear cells as a function of target cell proliferation. Immunology (1984) 0.75
Deficiency of NK activity of HNK-1+ cells after transplantation of fetal thymus and liver or haploidentical soybean agglutinin-treated marrow cells in two severe combined immunodeficiency patients. Clin Exp Immunol (1985) 0.75
Detection of T cells that secrete molecules which share determinants with antigen-specific T-cell factors. Proc Natl Acad Sci U S A (1981) 0.75
Surface markers and cytotoxic activity of blood natural killer cells studied at the single cell level in Hodgkin's disease. Clin Exp Immunol (1985) 0.75
Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene (2006) 4.06
Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte. Nat Immunol (2000) 3.58
THE ROLE OF THE LYMPHOCYTE IN ANTIBODY FORMATION. J Exp Med (1945) 3.45
Rhinovirus replication causes RANTES production in primary bronchial epithelial cells. Am J Respir Cell Mol Biol (1999) 1.77
Hypoxia inducible factor promotes murine allergic airway inflammation and is increased in asthma and rhinitis. Allergy (2011) 1.73
Inhibition of interleukin 10 by rituximab results in down-regulation of bcl-2 and sensitization of B-cell non-Hodgkin's lymphoma to apoptosis. Clin Cancer Res (2001) 1.59
Spontaneous cytotoxicity and tumor necrosis factor production by peripheral blood monocytes from AIDS patients. J Immunol (1988) 1.54
Natural killer cell immunodeficiency in HIV disease is manifest by profoundly decreased numbers of CD16+CD56+ cells and expansion of a population of CD16dimCD56- cells with low lytic activity. J Acquir Immune Defic Syndr Hum Retrovirol (1995) 1.53
Human tear lysozyme. II. Quantitative determination with standard Schirmer strips. Am J Ophthalmol (1968) 1.46
Evidence for several cell populations active in antibody dependent cellular cytotoxicity. J Immunol (1973) 1.44
Chimeric anti-CD20 (IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs. Cancer Biother Radiopharm (1997) 1.40
Diphtheria toxin- and Pseudomonas A toxin-mediated apoptosis. ADP ribosylation of elongation factor-2 is required for DNA fragmentation and cell lysis and synergy with tumor necrosis factor-alpha. J Immunol (1992) 1.39
Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction. Oncogene (2009) 1.34
Cellular immunoadsorbents: a simplified technique for separation of lymphoid cell populations. J Immunol (1974) 1.34
Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets (2011) 1.33
The SJL/J T cell response to both spontaneous and transplantable syngeneic reticulum cell sarcoma is mediated predominantly by the V beta 17a+ T cell clonotype. J Exp Med (1988) 1.30
Target-induced inactivation and cell death by apoptosis in a subset of human NK cells. J Immunol (1996) 1.30
Mechanism of cell-mediated cytotoxicity at the single cell level. II. Evidence for first-order kinetics of T cell-mediated cytolysis and for heterogeneity of lytic rate. J Immunol (1979) 1.29
Selective lysis of NK-sensitive target cells by a soluble mediator released from murine spleen cells and human peripheral blood lymphocytes. J Immunol (1981) 1.26
Internucleosomal DNA cleavage precedes diphtheria toxin-induced cytolysis. Evidence that cell lysis is not a simple consequence of translation inhibition. J Biol Chem (1989) 1.25
Aberrant expression of CD27 and soluble CD27 (sCD27) in HIV infection and in AIDS-associated lymphoma. Clin Immunol (1999) 1.24
Catalytic activity of caspase-3 is required for its degradation: stabilization of the active complex by synthetic inhibitors. Cell Death Differ (2004) 1.23
Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil. Eur J Cancer (2002) 1.22
Mode of action of interferon-mediated modulation of natural killer cytotoxic activity: recruitment of pre-NK cells and enhanced kinetics of lysis. J Immunol (1980) 1.21
Endogenous interleukin 6 is a resistance factor for cis-diamminedichloroplatinum and etoposide-mediated cytotoxicity of human prostate carcinoma cell lines. Cancer Res (1995) 1.15
Histamine-receptor leucocytes (HRL). Organ and lymphoid subpopulation distribution in man. Clin Exp Immunol (1977) 1.13
Resveratrol and cancer: chemoprevention, apoptosis, and chemo-immunosensitizing activities. Curr Med Chem Anticancer Agents (2003) 1.13
Concanavalin A-mediated activation of antigen-primed lymphocytes into secondary cytotoxic lymphocytes. J Exp Med (1977) 1.13
Histamine receptor-bearing leukocytes (HRL). I. Detection of histamine receptor-bearing cells by rosette formation with histamine-coated erythrocytes. J Immunol (1974) 1.13
Antibody-dependent cellular cytotoxicity against HIV-coated target cells by peripheral blood monocytes from HIV seropositive asymptomatic patients. J Immunol (1990) 1.13
Pivotal role of endogenous TNF-alpha in the induction of functional inactivation and apoptosis in NK cells. J Immunol (1997) 1.11
Target-induced anergy of natural killer cytotoxic function is restricted to the NK-target conjugate subset. Cell Immunol (1995) 1.11
Antibody-dependent cellular cytotoxicity (ADCC)-mediated destruction of human immunodeficiency virus (HIV)-coated CD4+ T lymphocytes by acquired immunodeficiency syndrome (AIDS) effector cells. J Clin Immunol (1988) 1.07
Lectin-dependent cellular cytotoxicity in man. Transplantation (1977) 1.06
Interferon-alpha activates cytotoxic function but inhibits interleukin-2-mediated proliferation and tumor necrosis factor-alpha secretion by immature human natural killer cells. J Clin Immunol (1995) 1.04
Rituximab inhibits the constitutively activated PI3K-Akt pathway in B-NHL cell lines: involvement in chemosensitization to drug-induced apoptosis. Oncogene (2007) 1.04
Antibody dependent cellular cytotoxicity: cytotoxicity mediated by non t-lymphocytes. Clin Immunol Immunopathol (1974) 1.03
Synergistic effect of tumor necrosis factor-alpha- and diphtheria toxin-mediated cytotoxicity in sensitive and resistant human ovarian tumor cell lines. J Immunol (1991) 1.03
Specific antibodies to dinucleotides and trinucleotides. Eur J Biochem (1972) 1.02
Interference with nuclear factor kappa B and c-Jun NH2-terminal kinase signaling by TRAF6C small interfering RNA inhibits myeloma cell proliferation and enhances apoptosis. Oncogene (2006) 1.02
Interleukin-6 induces G1 arrest through induction of p27(Kip1), a cyclin-dependent kinase inhibitor, and neuron-like morphology in LNCaP prostate tumor cells. Biochem Biophys Res Commun (1999) 1.02
The participation of the Fas-mediated cytotoxic pathway by natural killer cells is tumor-cell-dependent. Cancer Immunol Immunother (1997) 1.01
Significance of plasma cytokine levels in melanoma patients with histologically negative sentinel lymph nodes. Ann Surg Oncol (2001) 1.01
Specific enhancement of tumor growth and depression of cell-mediated immunity following sensitization to soluble tumor antigens. Cancer Res (1976) 0.99
Proteins in human tears. I. Immunoelectrophoretic patterns. Arch Ophthalmol (1969) 0.99
Regulation of B cell maturation and differentiation. I. Suppression of pokeweed mitogen-induced B cell differentiation by tumor necrosis factor (TNF). J Immunol (1987) 0.98
2-Methoxyestradiol (2-ME) reduces the airway inflammation and remodeling in an experimental mouse model. Clin Immunol (2008) 0.98
Prolonged asymptomatic states in HIV-seropositive persons with 50 CD4+ T-cells/mm3: preliminary psychoimmunologic findings. J Acquir Immune Defic Syndr (1993) 0.97
Mechanism of cell-mediated cytotoxicity at the single cell level. VIII. Kinetics of lysis of target cells bound by more than one cytotoxic T lymphocyte. J Immunol (1984) 0.96
Enhancement of sensitivity of urinary bladder tumor cells to cisplatin by c-myc antisense oligonucleotide. Cancer (1994) 0.96
Human tear lysozyme. 3. Preliminary study on lysozyme levels in subjects with smog eye irritation. Am J Ophthalmol (1968) 0.96
Overcoming tumor necrosis factor and drug resistance of human tumor cell lines by combination treatment with anti-Fas antibody and drugs or toxins. Cancer Res (1993) 0.95
Sensitization of AIDS-Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D. J Immunol (1999) 0.95
Propagation of mouse cytotoxic clones with characteristics of natural killer (NK) cells. Cell Immunol (1982) 0.95
Purification and characterization of cytolytic and noncytolytic human natural killer cell subsets. Proc Natl Acad Sci U S A (1990) 0.94
Differential regulation of human NK cell-associated gene expression following activation by IL-2, IFN-alpha and PMA/ionomycin. Int J Oncol (1998) 0.94
The SJL/J spontaneous reticulum cell sarcoma: new insights in the fields of neoantigens, host-tumor interactions, and regulation of tumor growth. Adv Cancer Res (1983) 0.93
Sensitization of human renal cell carcinoma cells to cis-diamminedichloroplatinum(II) by anti-interleukin 6 monoclonal antibody or anti-interleukin 6 receptor monoclonal antibody. Cancer Res (1995) 0.93
CD40 signaling replaces CD4+ lymphocytes and its blocking prevents chronic rejection of heart transplants. J Immunol (2000) 0.93
Synergistic cytotoxicity and apoptosis by Apo-2 ligand and adriamycin against bladder cancer cells. Clin Cancer Res (1999) 0.92
Differential secretion of TNF-alpha and IFN-gamma by human peripheral blood-derived NK subsets and association with functional maturation. J Clin Immunol (1996) 0.92
Autoimmunity and aging: the age-related response of mice of a long-lived strain to trinitrophenylated syngeneic mouse red blood cells. J Immunol (1976) 0.92
Immunological unresponsiveness induced in adult mice to synthetic polypeptides built on multichain polyproline and multichain polyalanine. Immunochemistry (1974) 0.92
Frequency determination of killer cells by a single-cell cytotoxic assay. Methods Enzymol (1983) 0.92
Chemosensitization of human prostate carcinoma cell lines to anti-fas-mediated cytotoxicity and apoptosis. Clin Cancer Res (1997) 0.92
Studies on the induction and expression of T cell-mediated immunity. I. Blocking of cell-mediated cytolysis by membrane antigens. J Immunol (1974) 0.91
Direct estimation of frequency of cytotoxic T lymphocytes by a modified plaque assay. Nature (1976) 0.91
Enhanced sensitivity of bladder cancer cells to tumor necrosis factor related apoptosis inducing ligand mediated apoptosis by cisplatin and carboplatin. J Urol (2001) 0.90
Studies on the induction and expression of T cell-mediated immunity. VIII. Effector-target junctions and target cell membrane disruption during cytolysis. Cell Immunol (1979) 0.90
Human tear lysozyme. I. Purification, physicochemical, and immunochemical characterization. J Lab Clin Med (1967) 0.90
MHC-Class I antigens regulate both the function and the survival of human peripheral blood NK cells: role of endogenously secreted TNF-alpha. Clin Immunol (2000) 0.90
Studies on the mechanism of natural killer cell-mediated cytotoxicity. VII. functional comparison of human natural killer cytotoxic factors with recombinant lymphotoxin and tumor necrosis factor. J Immunol (1987) 0.89
Antibody-mediated in vivo suppression of EL4 leukemia in a syngeneic host. J Natl Cancer Inst (1974) 0.89
HTLV-1 gene expression in adult T-cell leukemia cells elicits an NK cell response in vitro and correlates with cell rejection in SCID mice. Virology (1996) 0.89
Nitric oxide sensitizes ovarian tumor cells to Fas-induced apoptosis. Gynecol Oncol (1999) 0.89
Capacity of tumor necrosis factor to bind and penetrate membranes is pH-dependent. J Immunol (1988) 0.89
Mechanism of cell-mediated cytotoxicity at the single cell level. III. Evidence that cytotoxic T lymphocytes lyse both antigen-specific and -nonspecific targets pretreated with lectins or periodate. J Immunol (1981) 0.88
Actinomycin D and gemcitabine synergistically sensitize androgen-independent prostate cancer cells to Apo2L/TRAIL-mediated apoptosis. J Immunother (2001) 0.87
Immune functions characteristic of SJL/J mice and their association with age and spontaneous reticulum cell sarcoma. Cancer Res (1976) 0.87
Studies on the induction and expression of T cell-mediated immunity. II. Antiserum blocking of cell-mediated cytolysis. J Immunol (1974) 0.87
Immunosensitization of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity. Cell Immunol (1997) 0.87
Role of natural killer cytotoxic factors in the mechanism of target-cell killing by natural killer cells. J Clin Immunol (1986) 0.87
Structural basis for immune recognition of lysozymes. I. Effect of cyanogen bromide on hen egg-white lysozyme. Biochemistry (1969) 0.87
Inhibitory effects of 17beta-estradiol and progesterone on ovarian carcinoma cell proliferation: a potential role for inducible nitric oxide synthase. Gynecol Oncol (2001) 0.87