Published in J Immunol Methods on November 10, 1988
Role of antilipopolysaccharide antibodies in serum bactericidal activity against Salmonella enterica serovar Typhimurium in healthy adults and children in the United States. Clin Vaccine Immunol (2013) 1.03
Human alpha-defensins inhibit hemolysis mediated by cholesterol-dependent cytolysins. Infect Immun (2009) 1.01
Molecular characterization of the pig C3 gene and its association with complement activity. Immunogenetics (2003) 0.85
Effect of human immunodeficiency virus infection on plasma bactericidal activity against Salmonella enterica serovar Typhimurium. Clin Vaccine Immunol (2014) 0.83
Grifonin-1: a small HIV-1 entry inhibitor derived from the algal lectin, Griffithsin. PLoS One (2010) 0.82
Complete complement deficiency in a large cohort of familial systemic lupus erythematosus. Lupus (2009) 0.82
Use of serum or buffer-changed EDTA-plasma in a rapid, inexpensive, and easy-to-perform hemolytic complement assay for differential diagnosis of systemic lupus erythematosus and monitoring of patients with the disease. Clin Vaccine Immunol (2007) 0.80
Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity. Asian-Australas J Anim Sci (2015) 0.75
A systematic review and meta-analysis of early goal-directed therapy for septic shock: the ARISE, ProCESS and ProMISe Investigators. Intensive Care Med (2015) 4.95
Immune function in mice lacking the perforin gene. Proc Natl Acad Sci U S A (1994) 4.06
Isolation and biochemical and functional characterization of perforin 1 from cytolytic T-cell granules. Proc Natl Acad Sci U S A (1985) 3.31
Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs. Nat Med (1997) 2.61
Perforin: structure and function. Immunol Today (1995) 2.42
Mechanism of membrane damage mediated by human eosinophil cationic protein. Nature (1986) 2.41
Purification and characterization of a cytolytic pore-forming protein from granules of cloned lymphocytes with natural killer activity. Cell (1986) 2.38
Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines. Cancer Res (1998) 2.32
The gastrointestinal stimulus to insulin release. I. Secretin. J Clin Invest (1969) 2.24
Illicit transport: the oligopeptide permease. Proc Natl Acad Sci U S A (1973) 2.22
Cytolytic pore-forming proteins and peptides: is there a common structural motif? Trends Biochem Sci (1991) 2.22
The ninth component of complement and the pore-forming protein (perforin 1) from cytotoxic T cells: structural, immunological, and functional similarities. Science (1986) 2.21
Properties of the major outer membrane protein from Neisseria gonorrhoeae incorporated into model lipid membranes. Proc Natl Acad Sci U S A (1983) 2.20
Epiphora during the first year of life. Eye (Lond) (1991) 2.17
Cell death mechanisms and the immune system. Immunol Rev (1991) 2.07
Measurement and manipulation of pulmonary artery wedge pressure in adult respiratory distress syndrome. Anaesthesia (1991) 2.01
Development of the concept of a liquid pulmonary alveolar lining layer. Br J Anaesth (2001) 2.00
Multiple mechanisms of lymphocyte-mediated killing. Immunol Today (1988) 1.95
Functional assembly of gap junction conductance in lipid bilayers: demonstration that the major 27 kd protein forms the junctional channel. Cell (1987) 1.94
Comparison of mortality prediction models after open abdominal aortic aneurysm repair. Eur J Vasc Endovasc Surg (2006) 1.94
Characterization of a membrane pore-forming protein from Entamoeba histolytica. J Exp Med (1982) 1.85
The increase in intracellular free calcium associated with IgG gamma 2b/gamma 1 Fc receptor-ligand interactions: role in phagocytosis. Proc Natl Acad Sci U S A (1984) 1.83
Extracellular ATP as a trigger for apoptosis or programmed cell death. J Cell Biol (1991) 1.80
Macrophage membrane potential changes associated with gamma 2b/gamma 1 Fc receptor-ligand binding. Proc Natl Acad Sci U S A (1983) 1.70
Mouse macrophage Fc receptor for IgG gamma 2b/gamma 1 in artificial and plasma membrane vesicles functions as a ligand-dependent ionophore. Proc Natl Acad Sci U S A (1983) 1.64
Isolation and characterization of a serine esterase from cytolytic T cell granules. Cell (1986) 1.63
A randomised controlled trial of the effect of continuous electronic physiological monitoring on the adverse event rate in high risk medical and surgical patients. Anaesthesia (2006) 1.63
Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. J Exp Med (1989) 1.60
Outcome measures for adult critical care: a systematic review. Health Technol Assess (2000) 1.59
Nucleoside transporters: molecular biology and implications for therapeutic development. Mol Med Today (1999) 1.58
Role for mouse macrophage IgG Fc receptor as ligand-dependent ion channel. Nature (1984) 1.58
Resistance of cloned cytotoxic T lymphocytes to cell-mediated cytotoxicity. J Exp Med (1987) 1.58
Nucleoside transport in animal cells. Biosci Rep (1983) 1.56
Identification, isolation, and characterization of a novel cytotoxin in murine cytolytic lymphocytes. Cell (1987) 1.48
Effect of lysophosphatidic acid on motility, polarisation and metabolic burst of human neutrophils. FEMS Immunol Med Microbiol (1994) 1.48
Purified perforin induces target cell lysis but not DNA fragmentation. J Exp Med (1989) 1.47
Identification and characterization of a membrane-bound cytotoxin of murine cytolytic lymphocytes that is related to tumor necrosis factor/cachectin. Proc Natl Acad Sci U S A (1989) 1.47
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). J Biol Chem (2000) 1.44
Serum nitrates as markers of postoperative morbidity. Lancet (1994) 1.44
Ionophore-induced apoptosis: role of DNA fragmentation and calcium fluxes. Exp Cell Res (1991) 1.43
Functional channel formation associated with cytotoxic T-cell granules. Proc Natl Acad Sci U S A (1986) 1.43
Cytolysis mediated by ionophores and pore-forming agents: role of intracellular calcium in apoptosis. FASEB J (1994) 1.43
Extracellular ATP perturbs transmembrane ion fluxes, elevates cytosolic [Ca2+], and inhibits phagocytosis in mouse macrophages. J Biol Chem (1985) 1.43
Cytoskeletal and extracellular matrix proteins in cerebral arteries following subarachnoid hemorrhage in monkeys. J Neurosurg (1992) 1.43
Identification and characterization of a pore-forming protein of human peripheral blood natural killer cells. J Exp Med (1986) 1.41
Amino acid transport in human and in sheep erythrocytes. Proc R Soc Lond B Biol Sci (1980) 1.41
Right heart catheterization in intensive care. Br J Anaesth (2001) 1.40
The ENT family of eukaryote nucleoside and nucleobase transporters: recent advances in the investigation of structure/function relationships and the identification of novel isoforms. Mol Membr Biol (2001) 1.40
Bringing mind-body medicine into the mainstream. Hosp Pract (1995) (1997) 1.38
New method to evaluate the practice of positive pressure ventilation in intensive care units. Br J Anaesth (2003) 1.38
Synthesis of N- and O-linked glycopeptides in oviduct membrane preparations. J Biol Chem (1980) 1.37
Nucleoside transport in human and sheep erythrocytes. Evidence that nitrobenzylthioinosine binds specifically to functional nucleoside-transport sites. Biochem J (1980) 1.36
Cloning and functional expression of a complementary DNA encoding a mammalian nucleoside transport protein. J Biol Chem (1994) 1.35
Studies on the immune response to a characterized antigenic determinant of the tobacco mosaic virus protein. J Exp Med (1970) 1.34
Primary treatment choices for men with clinically localized prostate carcinoma detected by screening. Cancer (2000) 1.34
In vivo expression of perforin by CD8+ lymphocytes during an acute viral infection. J Exp Med (1989) 1.34
Perforin and lymphocyte-mediated cytolysis. Immunol Rev (1995) 1.34
Nucleoside translocation in sheep reticulocytes and fetal erythrocytes: a proposed model for the nucleoside transporter. J Physiol (1982) 1.31
Cell suicide in health and disease. Sci Am (1996) 1.31
Granulated metrial gland cells of pregnant mouse uterus are natural killer-like cells that contain perforin and serine esterases. J Immunol (1990) 1.30
Transport of organic substrates via a volume-activated channel. J Biol Chem (1992) 1.29
A national survey of the management of delirium in UK intensive care units. QJM (2010) 1.28
Value of nasal endoscopy and probing in the diagnosis and management of children with congenital epiphora. Br J Ophthalmol (2001) 1.28
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters. J Natl Cancer Inst (1999) 1.27
Properties of a purified pore-forming protein (perforin 1) isolated from H-2-restricted cytotoxic T cell granules. J Exp Med (1986) 1.27
Identification of a nucleoside/nucleobase transporter from Plasmodium falciparum, a novel target for anti-malarial chemotherapy. Biochem J (2000) 1.26
Extraction and partial purification of the nucleoside-transport system from human erythrocytes based on the assay of nitrobenzylthioinosine-binding activity. Biochem J (1981) 1.26
Simultaneous kinetic analysis of ribulose 1,5-bisphosphate carboxylase/oxygenase activities. Plant Physiol (1980) 1.26
Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues. J Biol Chem (1997) 1.25
Serum gastrin in patients with peptic ulceration. Br Med J (1970) 1.25
Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs. J Biol Chem (2001) 1.24
Recent advances in the molecular biology of nucleoside transporters of mammalian cells. Biochem Cell Biol (1998) 1.24
Nucleoside transport in sheep erythrocytes: genetically controlled transport variation and its influence on erythrocyte ATP concentrations. J Physiol (1978) 1.23
Relationship of effective molecular size to systemic clearance in rats of recombinant interleukin-2 chemically modified with water-soluble polymers. J Biol Chem (1988) 1.22
Antigenic determinants of proteins of defined sequences. Curr Top Microbiol Immunol (1972) 1.21
In vivo expression of perforin by CD8+ lymphocytes in autoimmune disease. Studies on spontaneous and adoptively transferred diabetes in nonobese diabetic mice. J Immunol (1989) 1.20
Extracellular release of lymphocyte cytolytic pore-forming protein (perforin) after ionophore stimulation. Proc Natl Acad Sci U S A (1986) 1.19
L-Tryptophan transport in human red blood cells. Biochim Biophys Acta (1980) 1.19
Expression of perforin and serine esterases by human gamma/delta T cells. J Exp Med (1991) 1.19
The fluorescein disappearance test (FDT): an evaluation of its use in infants. J Pediatr Ophthalmol Strabismus (1992) 1.18
Synthetic substrate for cyclic AMP-dependent protein kinase. Nature (1975) 1.18
Cell-mediated killing: a common mechanism? Cell (1986) 1.18
A national survey of intensive care follow-up clinics. Anaesthesia (2006) 1.18
Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta. Biochem J (1997) 1.17
Radioimmunoassay of pancreozymin cholecystokinin in human serum. J Nucl Med (1969) 1.17
The primary structure of the lymphocyte pore-forming protein perforin: partial amino acid sequencing and determination of isoelectric point. Biochem Biophys Res Commun (1988) 1.16
Prescribing generic drugs. Br J Gen Pract (1994) 1.16
Photoaffinity labeling of the human erythrocyte nucleoside transporter by N6-(p-Azidobenzyl)adenosine and nitrobenzylthioinosine. Evidence that the transporter is a band 4.5 polypeptide. J Biol Chem (1983) 1.15
Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1). Am J Physiol (1997) 1.15
Primary spheroidal degeneration of the cornea in Labrador and northern Newfoundland. Am J Ophthalmol (1975) 1.15
Erythrocyte nucleoside transport: asymmetrical binding of nitrobenzylthioinosine to nucleoside permeation sites. J Physiol (1982) 1.14
Indirect selection for auxotrophic mutants of Saccharomyces cerevisiae using the antibiotic netropsin. Mutat Res (1976) 1.14
Interleukin-15 induces the expression of mRNAs of cytolytic mediators and augments cytotoxic activities in primary murine lymphocytes. Cell Immunol (1996) 1.13
Fracture of penis: controversy of surgical versus conservative treatment. Urology (1984) 1.13
Resistance of cytolytic lymphocytes to perforin-mediated killing. Lack of correlation with complement-associated homologous species restriction. J Exp Med (1988) 1.13
The gastrointestinal stimulus to insulin release. II. A dual action of secretin. J Clin Invest (1970) 1.13
Cytolytic lymphocytes induce both apoptosis and necrosis in target cells. J Immunol (1991) 1.12
A Ca2+-activated channel from Xenopus laevis oocyte membranes reconstituted into planar bilayers. Proc Natl Acad Sci U S A (1984) 1.12
Is inosine the physiological energy source of pig erythrocytes? Biochim Biophys Acta (1980) 1.12