Published in Epilepsy Res on January 17, 1989
Key factors in the discovery and development of new antiepileptic drugs. Nat Rev Drug Discov (2010) 2.22
Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity. J Med Chem (2012) 0.92
A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage. Epilepsia (2011) 0.88
Neuronal Injury, Gliosis, and Glial Proliferation in Two Models of Temporal Lobe Epilepsy. J Neuropathol Exp Neurol (2016) 0.83
Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. Br J Pharmacol (2003) 0.78
Novel, broad-spectrum anticonvulsants containing a sulfamide group: pharmacological properties of (S)-N-[(6-chloro-2,3-dihydrobenzo[1,4]dioxin-2-yl)methyl]sulfamide (JNJ-26489112). J Med Chem (2013) 0.76
Comparative study of five antiepileptic drugs on a translational cognitive measure in the rat: relationship to antiepileptic property. Psychopharmacology (Berl) (2009) 0.76
Small-molecule anticonvulsant agents with potent in vitro neuroprotection and favorable drug-like properties. J Mol Neurosci (2013) 0.75
Low Frequency Electrical Stimulation Either Prior to Or after Rapid Kindling Stimulation Inhibits the Kindling-Induced Epileptogenesis. Biomed Res Int (2017) 0.75
Hospital-based pneumococcal immunization. Epidemiologic rationale from the Shenandoah study. JAMA (1990) 2.14
Hospital stay and mortality attributed to nosocomial enterococcal bacteremia: a controlled study. Am J Infect Control (1989) 1.98
Chronic traumatic thoracic aneurysm. Influence of operative treatment on natural history: an analysis of reported cases, 1950-1980. J Thorac Cardiovasc Surg (1982) 1.95
Multiple use of disposable insulin syringe-needle units. JAMA (1980) 1.89
Relation between surgical volume and incidence of postoperative wound infection. N Engl J Med (1981) 1.87
Clinical effectiveness of influenza vaccination in Manitoba. JAMA (1993) 1.78
Postinfarction ventricular septal rupture: the importance of location of infarction and right ventricular function in determining survival. Circulation (1986) 1.63
Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab (1987) 1.58
Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. N Engl J Med (1986) 1.56
Health perceptions of primary care patients and the influence on health care utilization. Med Care (1989) 1.53
Improving preventive care at a medical clinic: how can the patient help? Am J Prev Med (1990) 1.50
Hospital-acquired pneumonia. Attributable mortality and morbidity. Am J Epidemiol (1989) 1.48
Prediction of cardiac events after uncomplicated myocardial infarction: a prospective study comparing predischarge exercise thallium-201 scintigraphy and coronary angiography. Circulation (1983) 1.46
Comparison of outcome of asymptomatic to symptomatic patients older than 20 years of age with valvular aortic stenosis. Am J Cardiol (1988) 1.43
An exploration of the complex relationship of socioecologic factors in the treatment and outcomes of acute myocardial infarction in disadvantaged populations. Health Serv Res (2001) 1.38
Self-sustaining limbic status epilepticus induced by 'continuous' hippocampal stimulation: electrographic and behavioral characteristics. Epilepsy Res (1989) 1.37
Prediction of microbial aetiology at admission to hospital for pneumonia from the presenting clinical features. British Thoracic Society Pneumonia Research Subcommittee. Thorax (1989) 1.36
Contemporary aspects of discrete peak-detection algorithms. I. The paradigm of the luteinizing hormone pulse signal in men. Endocr Rev (1988) 1.33
Intranasal recombinant alfa-2b interferon treatment of naturally occurring common colds. Antimicrob Agents Chemother (1988) 1.25
Urinary tract etiology of bloodstream infections in hospitalized patients. J Infect Dis (1983) 1.24
Human pancreatic growth-hormone-releasing factor selectively stimulates growth-hormone secretion in man. Lancet (1983) 1.23
Relationships between aryl hydrocarbon hydroxylase inducibility and sensitivity to chemically induced subcutaneous sarcomas in various strains of mice. J Natl Cancer Inst (1973) 1.16
Risk factors for intermediate-term survival after coronary artery bypass grafting. Ann Thorac Surg (2001) 1.15
Ineffectiveness of oral terfenadine in natural colds: evidence against histamine as a mediator of common cold symptoms. Pediatr Infect Dis J (1988) 1.11
T-cells and macrophages in rapidly progressive glomerulonephritis: clinicopathologic correlations. Kidney Int (1987) 1.11
Kindling with rapidly recurring hippocampal seizures. Brain Res (1985) 1.10
RNA tumor-virus antigen expression in chemically induced tumors. Virus-genome-specified common antigens detected by complement fixation in mouse tumors induced by 3-methylcholanthrene. J Natl Cancer Inst (1971) 1.10
A comprehensive analysis of myocardial infarction due to left circumflex artery occlusion: comparison with infarction due to right coronary artery and left anterior descending artery occlusion. J Am Coll Cardiol (1988) 1.06
Acute non-Q wave myocardial infarction associated with early ST segment elevation: evidence for spontaneous coronary reperfusion and implications for thrombolytic trials. J Am Coll Cardiol (1987) 1.03
Acceptance of hepatitis B vaccine by medical and surgical residents. J Gen Intern Med (1988) 1.03
Extracorporeal perfusion of excised sigmoid colon segments. Surg Gynecol Obstet (1966) 1.02
Catheter-associated bacteriuria. Failure to reduce attack rates using periodic instillations of a disinfectant into urinary drainage systems. JAMA (1984) 1.01
Prognostic factors in head and neck melanoma. Effect of lesion location. Cancer (1988) 1.00
Organ-specific autoantibodies in children with common endocrine diseases. J Pediatr (1982) 1.00
Can success in the surgical residency be predicted from preresidency evaluation? Ann Surg (1985) 0.98
The prevalence and clinical significance of residual myocardial ischemia 2 weeks after uncomplicated non-Q wave infarction: a prospective natural history study. Circulation (1986) 0.97
A measurement of the efficacy of nosocomial infection control using the 95 per cent confidence interval for infection rates. Am J Epidemiol (1987) 0.96
Thyroid cancer: some basic considerations. Am J Surg (1981) 0.95
Selective peripheral dopamine-1 receptor stimulation with fenoldopam in human essential hypertension. J Clin Invest (1984) 0.95
Pulsatile growth hormone secretion in normal man during a continuous 24-hour infusion of human growth hormone releasing factor (1-40). Evidence for intermittent somatostatin secretion. J Clin Invest (1985) 0.95
Elements of informed consent for pharmacogenetic research; perspective of the pharmacogenetics working group. Pharmacogenomics J (2002) 0.94
Acute hypoxemia and hypercapnia: increase in plasma catecholamines in conscious dogs. Am J Physiol (1983) 0.94
Synergistic effects of acute hypoxemia and hypercapnic acidosis in conscious dogs. Renal dysfunction and activation of the renin-angiotensin system. Circ Res (1983) 0.93
Carotid endarterectomy after a completed stroke: reduction in long-term neurologic deterioration. J Vasc Surg (1985) 0.93
Relation between amiodarone and desethylamiodarone plasma concentrations and electrophysiologic effects, efficacy and toxicity. J Am Coll Cardiol (1987) 0.93
Double-blind randomized study of prophylactic trimethoprim/sulfamethoxazole in granulocytopenic patients with hematologic malignancies. Am J Med (1983) 0.93
Stimulation of growth hormone (GH) and somatomedin C in idiopathic GH-deficient subjects by intermittent pulsatile administration of synthetic human pancreatic tumor GH-releasing factor. J Clin Endocrinol Metab (1984) 0.92
Effects of long-term therapy with naltrexone on body weight in obesity. Clin Pharmacol Ther (1985) 0.92
Estimating the economic burden of status epilepticus to the health care system. Seizure (2005) 0.90
The effect of androgens on the pulsatile release and the twenty-four-hour mean concentration of growth hormone in peripubertal males. J Clin Endocrinol Metab (1986) 0.90
Effects of human pancreatic tumour growth hormone releasing factor on growth hormone and somatomedin C levels in patients with idiopathic growth hormone deficiency. Lancet (1983) 0.89
Storage of the isolated kidney with an extra-corporeal perfusion system. Exp Med Surg (1965) 0.88
Healthy patients who perceive poor health and their use of primary care services. J Gen Intern Med (1991) 0.87
Two randomized controlled trials of virucidal nasal tissues in the prevention of natural upper respiratory infections. Am J Epidemiol (1988) 0.87
Exercise-induced ST segment elevation 2 weeks after uncomplicated myocardial infarction: contributing factors and prognostic significance. J Am Coll Cardiol (1987) 0.87
Human pancreatic tumor growth hormone-releasing factor: dose-response relationships in normal man. J Clin Endocrinol Metab (1984) 0.87
Response properties of rapidly recurring hippocampal seizures in rats. Epilepsy Res (1989) 0.87
Survival of small intestine following excision, perfusion and autotransplantation. Ann Surg (1967) 0.87
Clinical identification of nondiabetic renal disease in diabetic patients with type I and type II disease presenting with renal dysfunction. Am J Nephrol (1988) 0.86
Intestinal preservation by hypothermia and hyperbaric oxygen. Ann Surg (1968) 0.86
Enumeration of lactotropes and somatotropes among male and female pituitary cells in culture: evidence in favor of a mammosomatotrope subpopulation in the rat. Endocrinology (1985) 0.86
Pergolide mesylate: its effects on circulating anterior pituitary hormones in man. J Clin Endocrinol Metab (1981) 0.85
Peripheral insulin release after pancreatic resection: the effect of decreased beta-cell mass with systemic or portal drainage. Endocrinology (1988) 0.85
Role of dopamine in the regulation of growth hormone secretion: dopamine and bromocriptine augment growth hormone (GH)-releasing hormone-stimulated GH secretion in normal man. J Clin Endocrinol Metab (1987) 0.84
Effects of thoracic volume and shape on electromechanical coupling in abdominal muscles. J Appl Physiol Respir Environ Exerc Physiol (1984) 0.84
Nosocomial urinary tract infections: secular trends, treatment and economics in a university hospital. J Urol (1983) 0.84
Immunologic response of the prostate to bacteriuria and bacterial prostatitis. I. Immunoglobulin concentrations in prostatic fluid. J Urol (1982) 0.84
Factors affecting immediate and long-term survival after emergent and elective splanchnic-systemic shunts. Ann Surg (1985) 0.83
Divergent influences of the structurally dissimilar calcium entry blockers, diltiazem and verapamil, on thyrotropin- and gonadotropin-releasing hormone-stimulated anterior pituitary hormone secretion in man. J Clin Endocrinol Metab (1985) 0.82
Effects of thymectomy, splenectomy and 3-methylcholanthrene on neoplasia expression, incidence and latency in AKR mice. Proc Soc Exp Biol Med (1972) 0.82
Seroepidemiology of hepatitis D (delta agent) and hepatitis B among Virginia State prisoners. Clin Ther (1987) 0.82
Prolonged effect of inhaled glycopyrrolate in asthma. Chest (1987) 0.82
Feline leukemia virus envelope glycoprotein vaccine: preparation and evaluation of immunizing potency in guinea pig and cat. J Natl Cancer Inst (1978) 0.82
Ca+2 dependence of gonadotropin-releasing hormone-stimulated luteinizing hormone secretion: in vitro studies using continuously perifused dispersed rat anterior pituitary cells. Endocrinology (1983) 0.82
Lack of in vivo somatotroph desensitization or depletion after 14 days of continuous growth hormone (GH)-releasing hormone administration in normal men and a GH-deficient boy. J Clin Endocrinol Metab (1989) 0.82
A retrospective cohort study of nosocomial diarrhea as a risk factor for nosocomial infection. J Infect Dis (1990) 0.82
Right ventricular performance during increased afterload impaired by hypercapnic acidosis in conscious dogs. Circ Res (1983) 0.81
Effects of intravenous, subcutaneous, and intranasal administration of growth hormone (GH)-releasing hormone-40 on serum GH concentrations in normal men. J Clin Endocrinol Metab (1985) 0.81
Nosocomial urinary tract infections cause wound infections postoperatively in surgical patients. Surg Gynecol Obstet (1983) 0.81
Recognition of anxiety and depression by residents in a general medicine clinic. J Med Educ (1982) 0.81
Nonphysician supervision of a very-low-calorie diet. Results in over 200 cases. Int J Obes (1981) 0.80
Comparison of indices used to detect hypoventilation during sleep. Respiration (1985) 0.80
The effects of oral iodized oil on intelligence, thyroid status, and somatic growth in school-age children from an area of endemic goiter. Am J Clin Nutr (1982) 0.80
Infection and immunization of cats with the Kawakami-Theilen strain of feline leukemia virus. Proc Soc Exp Biol Med (1979) 0.80
Intranasal administration of human pancreatic tumor GH-releasing factor-40 stimulates GH release in normal men. J Clin Endocrinol Metab (1983) 0.80
Suppression of basal and stimulated noradrenergic activities by the dopamine agonist bromocriptine in man. J Clin Endocrinol Metab (1983) 0.80
Alterations in neurotransmitter amino acids in hippocampal kindled seizures. Epilepsy Res (1989) 0.80
Human pancreatic growth hormone-releasing factor-40 (hpGRF-40) allows stimulation of GH release by TRH. Endocrinology (1983) 0.80
Dual effects of growth hormone (GH)-releasing hormone infusion in normal men: somatotroph desensitization and increase in releasable GH. J Clin Endocrinol Metab (1986) 0.79
Progenitor cell numbers (CFU-GM, CFU-D, and CFU-Mix) and hemopoietic recovery following autologous marrow transplantation. Exp Hematol (1989) 0.79
Random and Non-Random Coincidence Between Luteinizing Hormone Peaks and Follicle-Stimulating Hormone, Alpha Subunit, Prolactin and Gonadotropin-Releasing Hormone ulsations. J Neuroendocrinol (1989) 0.79
Chemical carcinogenesis in mice inhibited by interferon. Nat New Biol (1972) 0.79
Comparative assessments of objective peak-detection algorithms. II. Studies in men. Am J Physiol (1988) 0.79
Dopaminergic suppression of angiotensin II-induced aldosterone secretion in man: differential responses during sodium loading and depletion. Metabolism (1984) 0.79
Evidence for a limited growth hormone (GH)-releasing hormone (GHRH)-releasable quantity of GH: effects of 6-hour infusions of GHRH on GH secretion in normal man. J Clin Endocrinol Metab (1985) 0.79
Chronic partial ureteral obstruction in the neonatal guinea pig. I. Influence of uninephrectomy on growth and hemodynamics. Pediatr Res (1984) 0.79