Published in N Engl J Med on July 23, 1981
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Centralization of cancer surgery: implications for patient access to optimal care. J Clin Oncol (2009) 2.40
Long-term survival is superior after resection for cancer in high-volume centers. Ann Surg (2005) 2.38
Rural hospitals: a literature synthesis and health services research agenda. Health Serv Res (1989) 1.69
Differences among hospitals in Medicare patient mortality. Health Serv Res (1989) 1.69
Recurrence of inguinal hernias repaired in a large hernia surgical specialty hospital and general hospitals in Ontario, Canada. Can J Surg (2016) 1.59
A longitudinal analysis of the relationship between in-hospital mortality in New York State and the volume of abdominal aortic aneurysm surgeries performed. Health Serv Res (1992) 1.45
Outcomes of surgery among the Medicare aged: surgical volume and mortality. Health Care Financ Rev (1985) 1.26
The learning curve and the cost of heart transplantation. Health Serv Res (1992) 1.00
Regionalization of medical care. Am J Public Health (1985) 0.96
Effect of hospital volume of thyroidectomies on outcomes following substernal thyroidectomy. World J Surg (2008) 0.87
The centralization of operations and access to treatment: total hip replacement in Manitoba. Am J Public Health (1985) 0.86
Recent advances in the surgical care of breast cancer patients. World J Surg Oncol (2010) 0.86
Serious postoperative infections following resection of common solid tumors: outcomes, costs, and impact of hospital surgical volume. Support Care Cancer (2013) 0.84
The efficacy of postoperative prophylactic antibiotics in orthognathic surgery: a prospective study in Le Fort I osteotomy and bilateral intraoral vertical ramus osteotomy. Yonsei Med J (2009) 0.80
Impact of surgical training on incidence of surgical site infection. World J Surg (2009) 0.78
Cephalosporins in surgery. Prophylaxis and therapy. Drugs (1987) 0.76
Relation between surgical volume and postoperative wound infection. West J Med (1984) 0.75
Outcomes of surgery under Medicaid. Health Care Financ Rev (1990) 0.75
Nosocomial bloodstream infections in United States hospitals: a three-year analysis. Clin Infect Dis (1999) 10.30
The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA (1995) 9.54
Hospital-acquired candidemia. The attributable mortality and excess length of stay. Arch Intern Med (1988) 6.78
Response of man to infection with Vibrio cholerae. I. Clinical, serologic, and bacteriologic responses to a known inoculum. J Infect Dis (1974) 6.38
Nosocomial bloodstream infection in critically ill patients. Excess length of stay, extra costs, and attributable mortality. JAMA (1994) 6.11
Epidemiology of nosocomial infections caused by methicillin-resistant Staphylococcus aureus. Ann Intern Med (1982) 5.46
Comparative efficacy of alternative hand-washing agents in reducing nosocomial infections in intensive care units. N Engl J Med (1992) 5.28
Strategies to Prevent and Control the Emergence and Spread of Antimicrobial-Resistant Microorganisms in Hospitals. A challenge to hospital leadership. JAMA (1996) 4.80
Vancomycin-resistant Enterococcus faecium bacteremia: risk factors for infection. Clin Infect Dis (1995) 4.36
Coagulase-negative staphylococcal bacteremia. Mortality and hospital stay. Ann Intern Med (1989) 4.23
Enhanced isolation of Mycoplasma pneumoniae from throat washings with a newly-modified culture medium. J Infect Dis (1979) 4.15
Systemic inflammatory response syndrome, sepsis, severe sepsis and septic shock: incidence, morbidities and outcomes in surgical ICU patients. Intensive Care Med (1995) 3.75
Risk factors for candidal bloodstream infections in surgical intensive care unit patients: the NEMIS prospective multicenter study. The National Epidemiology of Mycosis Survey. Clin Infect Dis (2001) 3.75
National surveillance of nosocomial blood stream infection due to species of Candida other than Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. SCOPE Participant Group. Surveillance and Control of Pathogens of Epidemiologic. Diagn Microbiol Infect Dis (1998) 3.58
Vancomycin-resistant Staphylococcus aureus: perspectives on measures needed for control. Ann Intern Med (1996) 3.53
A controlled clinical trial of E5 murine monoclonal IgM antibody to endotoxin in the treatment of gram-negative sepsis. The XOMA Sepsis Study Group. JAMA (1991) 3.25
Elimination of coincident Staphylococcus aureus nasal and hand carriage with intranasal application of mupirocin calcium ointment. Ann Intern Med (1991) 3.24
Methicillin-resistant Staphylococcus aureus: introduction and spread within a hospital. Ann Intern Med (1980) 3.20
Risk factors for candidemia in Neonatal Intensive Care Unit patients. The National Epidemiology of Mycosis Survey study group. Pediatr Infect Dis J (2000) 3.13
Association of slime with pathogenicity of coagulase-negative staphylococci causing nosocomial septicemia. J Clin Microbiol (1985) 3.13
Percutaneous injuries during surgical procedures. JAMA (1992) 3.01
Retrospective study of the toxicity of preparations of vancomycin from 1974 to 1981. Antimicrob Agents Chemother (1983) 2.99
Risk factors for hospital-acquired candidemia. A matched case-control study. Arch Intern Med (1989) 2.97
National surveillance of nosocomial blood stream infection due to Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn Microbiol Infect Dis (1998) 2.94
Nosocomial bloodstream infections. Secular trends in rates, mortality, and contribution to total hospital deaths. Arch Intern Med (1995) 2.86
Transmission of rhinovirus colds by self-inoculation. N Engl J Med (1973) 2.80
Characterization of the sequence of colonization and nosocomial candidemia using DNA fingerprinting and a DNA probe. J Clin Microbiol (1990) 2.72
Efficient detection and long-term persistence of the carriage of methicillin-resistant Staphylococcus aureus. Clin Infect Dis (1994) 2.67
Microbiological factors influencing the outcome of nosocomial bloodstream infections: a 6-year validated, population-based model. Clin Infect Dis (1997) 2.67
National epidemiology of mycoses survey (NEMIS): variations in rates of bloodstream infections due to Candida species in seven surgical intensive care units and six neonatal intensive care units. Clin Infect Dis (1999) 2.63
National epidemiology of mycoses survey: a multicenter study of strain variation and antifungal susceptibility among isolates of Candida species. Diagn Microbiol Infect Dis (1998) 2.56
A second large controlled clinical study of E5, a monoclonal antibody to endotoxin: results of a prospective, multicenter, randomized, controlled trial. The E5 Sepsis Study Group. Crit Care Med (1995) 2.48
The emergence of methicillin-resistant Staphylococcus aureus. Ann Intern Med (1982) 2.32
Long-term survival and function after suspected gram-negative sepsis. JAMA (1995) 2.27
Nosocomial bloodstream infections caused by Acinetobacter species in United States hospitals: clinical features, molecular epidemiology, and antimicrobial susceptibility. Clin Infect Dis (2000) 2.22
Investigation of the sequence of colonization and candidemia in nonneutropenic patients. J Clin Microbiol (1994) 2.22
The epidemiology of intravenous vancomycin usage in a university hospital. A 10-year study. JAMA (1993) 2.18
Multiply-resistant Enterococcus faecium. The nosocomial pathogen of the 1990s. JAMA (1992) 2.15
Hospital-based pneumococcal immunization. Epidemiologic rationale from the Shenandoah study. JAMA (1990) 2.14
Methicillin-resistant Staphylococcus aureus: microbiologic characteristics, antimicrobial susceptibilities, and assessment of virulence of an epidemic strain. J Infect Dis (1981) 2.12
Handwashing compliance by health care workers: The impact of introducing an accessible, alcohol-based hand antiseptic. Arch Intern Med (2000) 2.10
Importance of pre-existing co-morbidities for prognosis of septicemia in critically ill patients. Intensive Care Med (1993) 2.05
Septic shock: an analysis of outcomes for patients with onset on hospital wards versus intensive care units. Crit Care Med (1998) 2.04
Smallpox vaccination for investigators using vaccinia recombinants. Lancet (1989) 2.00
Vancomycin-resistant enterococcal bacteremia: natural history and attributable mortality. Clin Infect Dis (1996) 1.99
Hospital stay and mortality attributed to nosocomial enterococcal bacteremia: a controlled study. Am J Infect Control (1989) 1.98
Nosocomial enterococcal blood stream infections in the SCOPE Program: antimicrobial resistance, species occurrence, molecular testing results, and laboratory testing accuracy. SCOPE Hospital Study Group. Diagn Microbiol Infect Dis (1997) 1.95
Postoperative wound infection: a controlled study of the increased duration of hospital stay and direct cost of hospitalization. Ann Surg (1977) 1.95
Chronic traumatic thoracic aneurysm. Influence of operative treatment on natural history: an analysis of reported cases, 1950-1980. J Thorac Cardiovasc Surg (1982) 1.95
Resistance to penicillin-streptomycin synergy among clinical isolates of viridans streptococci. Antimicrob Agents Chemother (1983) 1.93
Managing antibiotic resistance. N Engl J Med (2000) 1.90
Multiple use of disposable insulin syringe-needle units. JAMA (1980) 1.89
Associated mortality and clinical characteristics of nosocomial Pseudomonas maltophilia in a university hospital. J Clin Microbiol (1986) 1.84
Epidemiology of infections due to Pseudomonas aeruginosa. Rev Infect Dis (1987) 1.83
Comparison of protective effect of neutralizing antibody in serum and nasal secretions in experimental rhinovirus type 13 illness. Am J Epidemiol (1969) 1.82
Clinical effectiveness of influenza vaccination in Manitoba. JAMA (1993) 1.78
Comparative evaluation of an automated ribotyping system versus pulsed-field gel electrophoresis for epidemiological typing of clinical isolates of Escherichia coli and Pseudomonas aeruginosa from patients with recurrent gram-negative bacteremia. Diagn Microbiol Infect Dis (1996) 1.78
Nosocomial urinary tract infections due to enterococcus. Ten years' experience at a university hospital. Arch Intern Med (1986) 1.77
Enterococcal endocarditis: a comparison of prosthetic and native valve disease. Rev Infect Dis (1991) 1.77
Multiply resistant viridans streptococci: susceptibility to beta-lactam antibiotics and comparison of penicillin-binding protein patterns. Antimicrob Agents Chemother (1983) 1.74
Hospital-acquired bloodstream infections with Staphylococcus epidermidis. Review of 100 cases. Am J Med (1984) 1.74
Inducible amp C beta-lactamase producing gram-negative bacilli from blood stream infections: frequency, antimicrobial susceptibility, and molecular epidemiology in a national surveillance program (SCOPE). Diagn Microbiol Infect Dis (1997) 1.73
Anti-endotoxin monoclonal antibodies--a second look. N Engl J Med (1992) 1.73
Purpose of quality standards for infectious diseases. Infectious Diseases Society of America. Clin Infect Dis (1994) 1.70
Postinfarction ventricular septal rupture: the importance of location of infarction and right ventricular function in determining survival. Circulation (1986) 1.63
Coronavirus infections in military recruits. Three-year study with coronavirus strains OC43 and 229E. Am Rev Respir Dis (1974) 1.62
Plasma tumor necrosis factor levels in patients with presumed sepsis. Results in those treated with antilipid A antibody vs placebo. JAMA (1989) 1.59
Effects of sex and age on the 24-hour profile of growth hormone secretion in man: importance of endogenous estradiol concentrations. J Clin Endocrinol Metab (1987) 1.58
Influence of in vitro susceptibility testing conditions on the anti-candidal activity of LY121019. Diagn Microbiol Infect Dis (1988) 1.57
Emergence of coagulase negative staphylococci as major nosocomial bloodstream pathogens. Infect Control (1987) 1.57
Prevention of natural colds by contact prophylaxis with intranasal alpha 2-interferon. N Engl J Med (1986) 1.56
Quality standard for antimicrobial prophylaxis in surgical procedures. Infectious Diseases Society of America. Clin Infect Dis (1994) 1.56
Comparative in vitro activity of the new quinolone sparfloxacin (CI-978, AT-4140) against nosocomial gram-negative bloodstream isolates. Eur J Clin Microbiol Infect Dis (1990) 1.56
Outbreak of keratitis presumed to be caused by Acanthamoeba. Am J Ophthalmol (1996) 1.55
Hospital specificity, region specificity, and fluconazole resistance of Candida albicans bloodstream isolates. J Clin Microbiol (1998) 1.53
Health perceptions of primary care patients and the influence on health care utilization. Med Care (1989) 1.53
The use of biotyping and DNA fingerprinting in typing Candida albicans from hospitalized patients. Diagn Microbiol Infect Dis (1991) 1.52
Removal of nosocomial pathogens from the contaminated glove. Implications for glove reuse and handwashing. Ann Intern Med (1988) 1.51
In vitro activities of teichomycin, fusidic acid, flucloxacillin, fosfomycin, and vancomycin against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother (1984) 1.51
Improving preventive care at a medical clinic: how can the patient help? Am J Prev Med (1990) 1.50
Hospital-acquired pneumonia. Attributable mortality and morbidity. Am J Epidemiol (1989) 1.48
Nosocomial pneumonia in patients having bone marrow transplant. Attributable mortality and risk factors. Cancer (1992) 1.47
Hospital-acquired infections. I. Surveillance in a university hospital. Am J Epidemiol (1976) 1.47
Prediction of cardiac events after uncomplicated myocardial infarction: a prospective study comparing predischarge exercise thallium-201 scintigraphy and coronary angiography. Circulation (1983) 1.46
Ribosomal resistance of clinical enterococcal to streptomycin isolates. Antimicrob Agents Chemother (1984) 1.45
Elucidating the origins of nosocomial infections with Candida albicans by DNA fingerprinting with the complex probe Ca3. J Clin Microbiol (1999) 1.44
Risk factors for Candida species colonization of neonatal intensive care unit patients. Pediatr Infect Dis J (2001) 1.44
Cardiovascular surgery prophylaxis. A randomized, controlled comparison of cefazolin and cefuroxime. J Thorac Cardiovasc Surg (1990) 1.44
Vancomycin resistance in Staphylococcus haemolyticus causing colonization and bloodstream infection. J Clin Microbiol (1990) 1.44
Toxigenic bacterial diarrhea: nursery outbreak involving multiple bacterial strains. J Pediatr (1976) 1.44
Nosocomial infections: validation of surveillance and computer modeling to identify patients at risk. Am J Epidemiol (1990) 1.43
Hospital-acquired infections in intensive care unit patients: an overview with emphasis on epidemics. Infect Control (1983) 1.43
Expanding the treatment options for influenza. JAMA (2000) 1.43
Comparison of outcome of asymptomatic to symptomatic patients older than 20 years of age with valvular aortic stenosis. Am J Cardiol (1988) 1.43
Candida species: emerging hospital bloodstream pathogens. Infect Control Hosp Epidemiol (1991) 1.42
Evidence for protective effect of an inactivated rhinovirus vaccine administered by the nasal route. Am J Epidemiol (1969) 1.42
Bedside prediction of mortality from bacteremic sepsis. A dynamic analysis of ICU patients. Am J Respir Crit Care Med (1996) 1.40