Published in J Biol Chem on December 15, 1988
Diseases caused by defects in the visual cycle: retinoids as potential therapeutic agents. Annu Rev Pharmacol Toxicol (2007) 3.86
Retinoid absorption and storage is impaired in mice lacking lecithin:retinol acyltransferase (LRAT). J Biol Chem (2005) 2.28
Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage. Biochim Biophys Acta (2008) 1.89
Physiological insights into all-trans-retinoic acid biosynthesis. Biochim Biophys Acta (2011) 1.86
The cone-specific visual cycle. Prog Retin Eye Res (2010) 1.78
Retinol esterification in bovine retinal pigment epithelium: reversibility of lecithin:retinol acyltransferase. Biochem J (1993) 1.44
Comparative functional analysis of human medium-chain dehydrogenases, short-chain dehydrogenases/reductases and aldo-keto reductases with retinoids. Biochem J (2006) 1.33
The molecular basis of retinoid absorption: a genetic dissection. J Biol Chem (2008) 1.33
Retinol and retinyl esters: biochemistry and physiology. J Lipid Res (2013) 1.19
Retinyl ester formation by lecithin: retinol acyltransferase is a key regulator of retinoid homeostasis in mouse embryogenesis. J Biol Chem (2007) 1.18
Retinoic acid in the immune system. Ann N Y Acad Sci (2008) 1.09
Opposing actions of cellular retinol-binding protein and alcohol dehydrogenase control the balance between retinol storage and degradation. Biochem J (2004) 1.05
Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes. J Biol Chem (2010) 1.01
Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol). Crit Rev Food Sci Nutr (2009) 1.00
Retinoic acid regulation of the somitogenesis clock. Birth Defects Res C Embryo Today (2007) 0.95
The retinol dehydrogenase Rdh10 localizes to lipid droplets during acyl ester biosynthesis. J Biol Chem (2012) 0.93
Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activation. PLoS One (2012) 0.92
Retinoic acid receptors and GATA transcription factors activate the transcription of the human lecithin:retinol acyltransferase gene. Int J Biochem Cell Biol (2008) 0.91
Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue. J Lipid Res (2013) 0.90
Cloning, gene organization and identification of an alternative splicing process in lecithin:retinol acyltransferase cDNA from human liver. Gene (2004) 0.89
The retinol esterifying enzyme LRAT supports cell signaling by retinol-binding protein and its receptor STRA6. FASEB J (2013) 0.89
Localizations of visual cycle components in retinal pigment epithelium. Mol Vis (2009) 0.87
A novel isoenzyme of aldehyde dehydrogenase specifically involved in the biosynthesis of 9-cis and all-trans retinoic acid. Biochem J (1995) 0.86
Multiple pathways ensure retinoid delivery to milk: studies in genetically modified mice. Am J Physiol Endocrinol Metab (2009) 0.85
Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins. Biomed Res Int (2015) 0.85
Membrane receptors and transporters involved in the function and transport of vitamin A and its derivatives. Biochim Biophys Acta (2011) 0.84
Characterization of liver stellate cell retinyl ester storage. Biochem J (1994) 0.83
In vitro acylation of okadaic acid in the presence of various bivalves' extracts. Mar Drugs (2013) 0.82
Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis. Biochim Biophys Acta (2012) 0.81
Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases. Pharmacol Ther (2017) 0.75
Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids. J Biol Chem (2001) 1.56
Chylomicron remnant cholesteryl esters as the major constituent of very low density lipoproteins in plasma of cholesterol-fed rabbits. J Lipid Res (1977) 1.40
Selective inhibition of acyl coenzyme A:cholesterol acyltransferase by compound 58-035. J Biol Chem (1984) 1.37
Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A: retinol acyltransferase. J Biol Chem (1982) 1.34
Laboratory diagnosis of epidemic keratoconjunctivitis. J Med Microbiol (1969) 1.34
Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats. J Lipid Res (1996) 1.22
Lecithin:retinol acyltransferase from mouse and rat liver. CDNA cloning and liver-specific regulation by dietary vitamin a and retinoic acid. J Lipid Res (2000) 1.20
Lipoprotein lipase expression level influences tissue clearance of chylomicron retinyl ester. J Lipid Res (1999) 1.17
Characterization of a bile salt-dependent cholesteryl ester hydrolase activity secreted from HepG2 cells. Biochim Biophys Acta (1992) 1.16
Antibody production in vitamin A-depleted rats is impaired after immunization with bacterial polysaccharide or protein antigens. FASEB J (1990) 1.13
Endoprosthetic replacement of the proximal humerus. J Bone Joint Surg Br (1987) 1.09
Regulation of CYP26 (cytochrome P450RAI) mRNA expression and retinoic acid metabolism by retinoids and dietary vitamin A in liver of mice and rats. FASEB J (2000) 1.08
Intestinal absorption of dietary cholesteryl ester is decreased but retinyl ester absorption is normal in carboxyl ester lipase knockout mice. Biochemistry (1999) 1.08
The binding protein for retinol from rat testis cytosol. Isolation and partial characterization. J Biol Chem (1978) 1.07
Retinol esterification by mammary gland microsomes from the lactating rat. J Lipid Res (1982) 1.06
Endoprosthetic replacement of the humerus and elbow joint. J Bone Joint Surg Br (1987) 1.05
Fatty acyl CoA-dependent and -independent retinol esterification by rat liver and lactating mammary gland microsomes. Arch Biochem Biophys (1991) 1.02
All-trans-retinoic acid and polyriboinosinic : polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity. Immunology (2001) 1.02
Subcellular localization of retinoids, retinoid-binding proteins, and acyl-CoA:retinol acyltransferase in rat liver. J Lipid Res (1987) 1.01
Vitamin A during lactation: relationship of maternal diet to milk vitamin A content and to the vitamin A status of lactating rats and their pups. J Nutr (1985) 1.01
Separation and quantitation of retinyl esters and retinol by high-performance liquid chromatography. Methods Enzymol (1986) 1.00
Vitamin A status regulates hepatic lecithin: retinol acyltransferase activity in rats. J Biol Chem (1991) 0.97
The metabolism of dl-(1,6-14C)lipoic acid in the rat. Arch Biochem Biophys (1974) 0.97
Relation of serum retinol to acute phase proteins and malarial morbidity in Papua New Guinea children. Am J Clin Nutr (2000) 0.97
Chronic marginal vitamin A status reduces natural killer cell number and function in aging Lewis rats. J Nutr (1999) 0.94
Retinoic acid repletion restores the number of leukocytes and their subsets and stimulates natural cytotoxicity in vitamin A-deficient rats. J Nutr (1995) 0.94
Snow-and-ice fracture in the UK, a preventable epidemic. Lancet (1988) 0.94
Fluorometric assay for rat liver peroxisomal fatty acyl-coenzyme A oxidase activity. J Lipid Res (1983) 0.93
Distributions of carotenoids and alpha-tocopherol among lipoproteins do not change when human plasma is incubated in vitro. J Nutr (1995) 0.92
Carboxyl ester lipase overexpression in rat hepatoma cells and CEL deficiency in mice have no impact on hepatic uptake or metabolism of chylomicron-retinyl ester. Biochemistry (1999) 0.92
The antibody response of vitamin A-deficient rats to pneumococcal polysaccharide is enhanced through coimmunization with lipopolysaccharide. J Infect Dis (1994) 0.92
Fatty acid delta(5)-desaturase mRNA is regulated by dietary vitamin A and exogenous retinoic acid in liver of adult rats. Arch Biochem Biophys (2001) 0.92
Regulation of hepatic lecithin: retinol acyltransferase activity by retinoic acid. Arch Biochem Biophys (1993) 0.91
Hepatic uptake and metabolism of chylomicron retinyl esters: probable role of plasma membrane/endosomal retinyl ester hydrolases. J Lipid Res (1995) 0.91
Hydrolysis of retinyl esters by pancreatic triglyceride lipase. Biochemistry (2000) 0.89
Differential effects of fish oil, safflower oil and palm oil on fatty acid oxidation and glycerolipid synthesis in rat liver. J Nutr (1991) 0.89
Retinyl ester secretion by intestinal cells: a specific and regulated process dependent on assembly and secretion of chylomicrons. J Lipid Res (2001) 0.89
Potentiation of interferon-gamma-stimulated nitric oxide production by retinoic acid in RAW 264.7 cells. J Leukoc Biol (2001) 0.87
Chronic vitamin A intake affects the expression of mRNA for apolipoprotein A-I, but not for nuclear retinoid receptors, in liver of young and aging Lewis rats. Arch Biochem Biophys (1995) 0.87
Vitamin A status and immunoglobulin G subclasses in rats immunized with tetanus toxoid. FASEB J (1993) 0.86
Acute inflammation induces hyporetinemia and modifies the plasma and tissue response to vitamin A supplementation in marginally vitamin A-deficient rats. J Nutr (1998) 0.86
All-trans-retinoic acid and polyriboinosinoic:polyribocytidylic acid cooperate to elevate anti-tetanus immunoglobulin G and immunoglobulin M responses in vitamin A-deficient lewis rats and Balb/c mice. Proc Nutr Soc (2000) 0.86
Effects of N-(4-hydroxyphenyl)-retinamide on the number and cytotoxicity of natural killer cells in vitamin-A-sufficient and -deficient rats. Nat Immun (1995) 0.86
Chronic marginal vitamin A status affects the distribution and function of T cells and natural T cells in aging Lewis rats. J Nutr (1999) 0.85
Immunological memory to tetanus toxoid is established and maintained in the vitamin A-depleted rat. FASEB J (1991) 0.85
Production and secretion of retinol-binding protein by a human hepatoma cell line, HepG2. J Lipid Res (1987) 0.84
Early catastrophic tibial component wear after unicompartmental knee arthroplasty. Clin Orthop Relat Res (1998) 0.84
Regulation of hepatic vitamin A storage in a rat model of controlled vitamin A status during aging. J Nutr (2000) 0.84
2,3,7,8-tetrachlorodibenzo-p-dioxin increases serum and kidney retinoic acid levels and kidney retinol esterification in the rat. Toxicol Appl Pharmacol (2000) 0.83
Inflammation in human immunodeficiency virus type 1 infection as a cause of decreased plasma retinol. J Infect Dis (1996) 0.83
The role of vitamin A in natural killer cell cytotoxicity, number and activation in the rat. Nat Immun (1994) 0.82
Purification and characterization of a neutral, bile salt-independent retinyl ester hydrolase from rat liver microsomes. Relationship To rat carboxylesterase ES-2. J Biol Chem (1997) 0.82
Antibody response against tetanus toxoid is enhanced by lipopolysaccharide or tumor necrosis factor-alpha in vitamin A-sufficient and deficient rats. Am J Clin Nutr (1994) 0.82
Expression in Xenopus oocytes of rat liver mRNA coding for a bile salt-dependent cholesteryl ester hydrolase. Proc Natl Acad Sci U S A (1989) 0.82
Iron status and stores decline with age in Lewis rats. J Nutr (2000) 0.82
Iron deficiency in young rats alters the distribution of vitamin A between plasma and liver and between hepatic retinol and retinyl esters. J Nutr (1999) 0.82
Low fat and high monounsaturated fat diets decrease human low density lipoprotein oxidative susceptibility in vitro. J Nutr (2001) 0.82
Effect of vitamin A deficiency and retinoic acid repletion on intestinal and hepatic apolipoprotein A-I mRNA levels of adult rats. J Lipid Res (1994) 0.82
Dietary supplementation with beta-carotene, but not with lycopene, inhibits endothelial cell-mediated oxidation of low-density lipoprotein. Free Radic Biol Med (1999) 0.81
The binding protein for retinoic acid from rat testis cytosol: isolation and partial characterization. J Lipid Res (1980) 0.81
Regulation of thyroid-stimulating hormone beta-subunit and growth hormone messenger ribonucleic acid levels in the rat: effect of vitamin A status. Endocrinology (1995) 0.81
Regulation of hepatic lecithin:retinol acyltransferase activity by retinoic acid receptor-selective retinoids. Arch Biochem Biophys (1997) 0.81
Vitamin A deficiency decreases natural killer cell activity and interferon production in rats. J Nutr (1990) 0.81
Tissue and species differences in bile salt-dependent neutral cholesteryl ester hydrolase activity and gene expression. Arterioscler Thromb (1992) 0.81
Neutral and acid retinyl ester hydrolases associated with rat liver microsomes: relationships to microsomal cholesteryl ester hydrolases. J Lipid Res (1991) 0.80
N-(4-hydroxyphenyl)-retinamide increases lecithin:retinol acyltransferase activity in rat liver. J Nutr (1996) 0.80
Isolated avulsion of the tibial attachment of the posterior cruciate ligament in childhood. J Bone Joint Surg Br (1986) 0.80
Characterization of rat lymphocyte cell membranes by analytical isopycnic centrifugation. J Biol Chem (1983) 0.80
Vitamin A depletion and repletion: effects on antibody response to the capsular polysaccharide of Streptococcus pneumoniae, type III (SSS-III). Am J Clin Nutr (1989) 0.79
Chylomicron remnant-vitamin A metabolism by the human hepatoma cell line HepG2. J Lipid Res (1987) 0.79
A high-legume low-glycemic index diet reduces fasting plasma leptin in middle-aged insulin-resistant and -sensitive men. Eur J Clin Nutr (2011) 0.79
Regulation of retinol uptake and esterification in MCF-7 and HepG2 cells by exogenous fatty acids. J Lipid Res (1991) 0.78
Synthesis and degradation of fatty acid ethyl esters by cultured hepatoma cells exposed to ethanol. J Biol Chem (1990) 0.78
Separation of long-chain fatty acid esters of retinol by high-performance liquid chromatography. Anal Biochem (1981) 0.78
Action of clofibrate and its analogs in rats. Dissociation of hypolipidemic effects and the induction of peroxisomal beta-oxidation. Biochim Biophys Acta (1984) 0.78
Vitamin A status and the immune response to pneumococcal polysaccharide: effects of age and early stages of retinol deficiency in rats. J Nutr (1991) 0.78
Enzymatic composition of mitogen-induced lymphoblasts and untreated lymphocytes fractionated by rate-zonal centrifugation. Biochim Biophys Acta (1981) 0.78
Immunologic memory is established in nursling rats immunized with tetanus toxoid, but is not affected by concurrent supplementation with vitamin A. Am J Clin Nutr (1995) 0.78
Effects of timing and dose of vitamin A on tissue retinol concentrations and antibody production in the previously vitamin A-depleted rats. Am J Clin Nutr (1992) 0.78
Unusual properties of retinyl palmitate hydrolase activity in rat liver. J Lipid Res (1979) 0.78
Dietary vitamin A restriction produces marginal vitamin A status in young rats. J Nutr (1993) 0.77
Retinoic acid and tumor necrosis factor-α induced monocytic cell gene expression is regulated in part by induction of transcription factor MafB. Exp Cell Res (2012) 0.77
α-Galactosylceramide stimulates splenic lymphocyte proliferation in vitro and increases antibody production in vivo in late neonatal-age mice. Clin Exp Immunol (2015) 0.77
Molecular cloning of the cDNA for rat hepatic, bile salt-dependent cholesteryl ester/retinyl ester hydrolase demonstrates identity with pancreatic carboxylester lipase. Proc Soc Exp Biol Med (1997) 0.77
Synthesis of retinol-binding protein and transthyretin in yolk sac and fetus in the rat. J Nutr (1987) 0.77
Effects of food or nutrient restriction on milk vitamin A transfer and neonatal vitamin A stores in the rat. Br J Nutr (1990) 0.76
Vitamin A supplementation as therapy--are the benefits disease specific? Am J Clin Nutr (1998) 0.76
Effect of fatty acid supplementation on cholesterol and retinol esterification in J774 macrophages. Biochim Biophys Acta (1988) 0.76
Bile salt-independent retinyl ester hydrolase activities associated with membranes of rat tissues. Methods Enzymol (1990) 0.76
Impact of LDL carotenoid and alpha-tocopherol content on LDL oxidation by endothelial cells in culture. J Lipid Res (1998) 0.76
Mutations in the gene encoding retinol binding protein and retinol deficiency: is there compensation by retinyl esters and retinoic acid? Am J Clin Nutr (1999) 0.75
Addressing research questions with national survey data-the relation of vitamin A status to infection and inflammation. Am J Clin Nutr (2000) 0.75
Osteoarthritis of the hip in farmers. BMJ (1992) 0.75
Case report. Recovery of shoulder movement in patients with complete axillary nerve palsy. Ann R Coll Surg Engl (1998) 0.75