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Senescent Stromal Cells Promote Cancer Resistance through SIRT1 Loss-Potentiated Overproduction of Small Extracellular Vesicles.

PubWeight™: 4.96‹?› | Rank: Top 1%

🔗 View Article (PMID 32366480)

Published in Cancer Res on May 04, 2020

Authors

Liu Han1, Qilai Long2, Shenjun Li3, Qixia Xu4, Boyi Zhang1, Xuefeng Dou1, Min Qian1, Yannasittha Jiramongkol5, Jianming Guo2, Liu Cao6, Y Eugene Chin7, Eric W-F Lam5, Jing Jiang8, Yu Sun9,4,10

Author Affiliations

1: CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
2: Department of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
3: Non-Clinical Research Department, RemeGen, Ltd. Yantai, Shandong, China.
4: Institute of Health Sciences, Shanghai Jiao Tong University School of Medicine and Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
5: Department of Surgery and Cancer, Imperial College London, London, United Kingdom.
6: Key Laboratory of Medical Cell Biology, China Medical University, Shenyang, China.
7: Institute of Biology and Medical Sciences, Soochow University Medical College, Suzhou, Jiangsu, China.
8: Department of Pharmacology, Binzhou Medical University, Yantai, Shandong, China.
9: CAS Key Laboratory of Tissue Microenvironment and Tumor, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. sunyu@sibs.ac.cn.
10: Department of Medicine and VAPSHCS, University of Washington, Seattle, Washington.

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