Adenosine, deoxyadenosine, and deoxyguanosine induce DNA cleavage in mouse thymocytes.

PubWeight™: 0.99‹?› | Rank: Top 15%

🔗 View Article (PMID 3261757)

Published in J Immunol on September 01, 1988

Authors

H Kizaki1, H Shimada, F Ohsaka, T Sakurada

Author Affiliations

1: Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan.

Articles citing this

Apoptosis as a mechanism of cell death in cultured T lymphoblasts acutely infected with HIV-1. J Clin Invest (1991) 2.82

Apoptosis within spontaneously accepted mouse liver allografts: evidence for deletion of cytotoxic T cells and implications for tolerance induction. J Immunol (1997) 1.81

Adenosine A2A receptor activation protects CD4+ T lymphocytes against activation-induced cell death. FASEB J (2010) 1.00

Insights into thymic purine metabolism and adenosine deaminase deficiency revealed by transgenic mice overexpressing ecto-5'-nucleotidase (CD73). J Clin Invest (1997) 0.91

Skeletal muscle phenotypically converts and selectively inhibits metastatic cells in mice. PLoS One (2010) 0.84

Point mutations at the purine nucleoside phosphorylase locus impair thymocyte differentiation in the mouse. Proc Natl Acad Sci U S A (1997) 0.82

Apoptosis in human thymocytes after treatment with glucocorticoids. Clin Exp Immunol (1992) 0.82

The binding site of human adenosine deaminase for CD26/Dipeptidyl peptidase IV: the Arg142Gln mutation impairs binding to cd26 but does not cause immune deficiency. J Exp Med (2000) 0.81

The 2-chlorodeoxyadenosine-induced cell death signalling pathway in human thymocytes is different from that induced by 2-chloroadenosine. Biochem J (1995) 0.79

Clinical expression, genetics and therapy of adenosine deaminase (ADA) deficiency. J Inherit Metab Dis (1997) 0.78

Regulation of the salvage pathway of deoxynucleotides synthesis in apoptosis induced by growth factor deprivation. Biochem J (1996) 0.78

Articles by these authors

(truncated to the top 100)

The transcriptional landscape of the mammalian genome. Science (2005) 37.63

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models. Bioinformatics (2003) 32.92

The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression. EMBO J (1986) 19.59

The complete sequence of the rice (Oryza sativa) chloroplast genome: intermolecular recombination between distinct tRNA genes accounts for a major plastid DNA inversion during the evolution of the cereals. Mol Gen Genet (1989) 9.53

Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid. Children's Cancer Group. N Engl J Med (1999) 9.02

Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays. Proc Natl Acad Sci U S A (2001) 6.07

Mobilization of transposons by a mutation abolishing full DNA methylation in Arabidopsis. Nature (2001) 4.71

Histopathologic prognostic factors in neuroblastic tumors: definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas. J Natl Cancer Inst (1984) 4.01

Prevalence of serum and salivary antibodies to HTLV-1 in Sjögren's syndrome. Lancet (1994) 3.83

Metastatic sites in stage IV and IVS neuroblastoma correlate with age, tumor biology, and survival. J Pediatr Hematol Oncol (1999) 3.35

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases. Proc Natl Acad Sci U S A (2000) 3.24

Classification of rhabdomyosarcomas and related sarcomas. Pathologic aspects and proposal for a new classification--an Intergroup Rhabdomyosarcoma Study. Cancer (1995) 3.11

Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Oncology Group. J Clin Oncol (2005) 2.97

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques. Neuron (1995) 2.90

Prospective randomized study of open versus laparoscopy-assisted distal gastrectomy with extraperigastric lymph node dissection for early gastric cancer. Surg Endosc (2005) 2.13

Antroduodenal motility and transpyloric fluid movement in patients with diabetes studied using duplex sonography. Gastroenterology (1994) 2.12

Computer-aided Prognosis of Neuroblastoma on Whole-slide Images: Classification of Stromal Development. Pattern Recognit (2009) 2.12

JC virus detection by in situ hybridization in brain tissue from elderly patients. Ann Neurol (1991) 2.09

Role of neoadjuvant chemotherapy in the treatment of multiple colorectal metastases to the liver. Br J Surg (2003) 2.04

Effects of combination treatment with FK506 and cyclosporine on survival time and vascular changes in renal-allograft-recipient dogs. Transplantation (1989) 2.03

Cancer invasion and micrometastasis visualized in live tissue by green fluorescent protein expression. Cancer Res (1997) 2.00

Monitoring of methyl jasmonate-responsive genes in Arabidopsis by cDNA macroarray: self-activation of jasmonic acid biosynthesis and crosstalk with other phytohormone signaling pathways. DNA Res (2001) 1.92

Preferential susceptibility of brain tumors to the antiangiogenic effects of an alpha(v) integrin antagonist. Neurosurgery (2001) 1.90

Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J Natl Cancer Inst (1993) 1.88

Successful treatment of stage III neuroblastoma based on prospective biologic staging: a Children's Cancer Group study. J Clin Oncol (1998) 1.88

Two types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2001) 1.84

The nucleotide sequences of two tRNAAsn genes from tobacco chloroplasts. Nucleic Acids Res (1981) 1.84

Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: finding of a lipase motif and the induction by methyl jasmonate. Proc Natl Acad Sci U S A (1999) 1.79

Association between gain-of-function mutations in PIK3CA and resistance to HER2-targeted agents in HER2-amplified breast cancer cell lines. Ann Oncol (2009) 1.76

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation. Proc Natl Acad Sci U S A (1989) 1.75

Biologic variables in the outcome of stages I and II neuroblastoma treated with surgery as primary therapy: a children's cancer group study. J Clin Oncol (2000) 1.74

Alteration of the structural properties of starch components by the lack of an isoform of starch branching enzyme in rice seeds. J Biol Chem (1993) 1.71

Inhibition of invasion and metastasis in cells transfected with an inhibitor of metalloproteinases. Cancer Res (1992) 1.70

Muscle-specific calpain, p94, responsible for limb girdle muscular dystrophy type 2A, associates with connectin through IS2, a p94-specific sequence. J Biol Chem (1995) 1.68

Superiority of a new UICC-TNM staging system for gastric carcinoma. Surgery (2000) 1.67

Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae. II. The isolation and dosage effect of the regulatory gene GAL80. Mol Gen Genet (1984) 1.62

Pancreaticobiliary maljunction: retrospective and nationwide survey in Japan. J Hepatobiliary Pancreat Surg (2003) 1.62

Molecular differential pathology of rhabdomyosarcoma. Genes Chromosomes Cancer (1989) 1.59

Opsoclonus-myoclonus-ataxia syndrome in neuroblastoma: clinical outcome and antineuronal antibodies-a report from the Children's Cancer Group Study. Med Pediatr Oncol (2001) 1.58

Widespread skeletal metastatic potential of human lung cancer revealed by green fluorescent protein expression. Cancer Res (1998) 1.55

Evidence for compound I formation in the reaction of cytochrome P450cam with m-chloroperbenzoic acid. Biochem Biophys Res Commun (1994) 1.52

Neurofibrillary tangles in human upper cervical ganglia. Morphological study with immunohistochemistry and electron microscopy. Acta Neuropathol (1987) 1.48

Basic fibroblast growth factor stimulates repair of wounded hepatocyte monolayer: modulatory role of protein kinase A and extracellular matrix. J Lab Clin Med (1999) 1.47

A fluorescent orthotopic bone metastasis model of human prostate cancer. Cancer Res (1999) 1.46

Regional cerebral oxygen saturation during electroconvulsive therapy: monitoring by near-infrared spectrophotometry. Anesth Analg (1996) 1.45

Favorable biology and outcome of stage IV-S neuroblastoma with supportive care or minimal therapy: a Children's Cancer Group study. J Clin Oncol (2000) 1.44

Identification, cDNA cloning, and gene expression of soluble starch synthase in rice (Oryza sativa L.) immature seeds. Plant Physiol (1993) 1.43

Muscle-specific gene expression in rhabdomyosarcomas and stages of human fetal skeletal muscle development. Cancer Res (1991) 1.42

Blue-dye technique complements four-node sampling for early breast cancer. Eur J Surg Oncol (2005) 1.41

Outer membrane protein A-promoted actin condensation of brain microvascular endothelial cells is required for Escherichia coli invasion. Infect Immun (1999) 1.40

Controlled transcription of the yeast regulatory gene GAL80. Gene (1985) 1.40

Biologic factors determine prognosis in infants with stage IV neuroblastoma: A prospective Children's Cancer Group study. J Clin Oncol (2000) 1.40

Dominant lethal study in male mice treated with ofloxacin, a new antimicrobial drug. Mutat Res (1985) 1.39

Phosphoglucomutase. V. Multiple forms of phosphoglucomutase. Proc Natl Acad Sci U S A (1967) 1.38

Long-term thrombosis after transvenous permanent pacemaker implantation. Pacing Clin Electrophysiol (1998) 1.38

In vivo tumor delivery of the green fluorescent protein gene to report future occurrence of metastasis. Cancer Gene Ther (2000) 1.37

Functional defects of a muscle-specific calpain, p94, caused by mutations associated with limb-girdle muscular dystrophy type 2A. J Biol Chem (1998) 1.36

Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters. J Immunol (1989) 1.35

Genomic organization of 251 kDa acetyl-CoA carboxylase genes in Arabidopsis: tandem gene duplication has made two differentially expressed isozymes. Plant Cell Physiol (1995) 1.34

Dynamic protein structures: infrared evidence for four discrete rapidly interconverting conformers at the carbon monoxide binding site of bovine heart myoglobin. Proc Natl Acad Sci U S A (1981) 1.34

Metabolic engineering for the production of carotenoids in non-carotenogenic bacteria and yeasts. J Biotechnol (1997) 1.34

A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: histochemical detection and possible physiological role. Endocrinology (1994) 1.34

An Arabidopsis cell cycle -dependent kinase-related gene, CDC2b, plays a role in regulating seedling growth in darkness. Plant Cell (1999) 1.30

Molecular cloning and sequencing of human cDNA for phosphoribosyl pyrophosphate synthetase subunit II. FEBS Lett (1989) 1.29

Idiopathic hypertrophic subaortic stenosis diagnosed by reflected ultrasound. Am J Cardiol (1969) 1.29

Primary and metastatic rhabdomyosarcoma in the breast: neoplasms of adolescent females, a report from the Intergroup Rhabdomyosarcoma Study. Med Pediatr Oncol (1997) 1.25

Ultrastructure of the Bunina bodies in anterior horn cells of amyotrophic lateral sclerosis. Acta Neuropathol (1978) 1.25

Histopathology of childhood sarcomas, Intergroup Rhabdomyosarcoma Studies I and II: clinicopathologic correlation. J Clin Oncol (1988) 1.24

Male sexual function after autonomic nerve-preserving operation for rectal cancer. Dis Colon Rectum (1996) 1.24

Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage. J Biol Chem (1990) 1.23

Primary Sjögren's syndrome with antibodies to HTLV-I: clinical and laboratory features. Ann Rheum Dis (1992) 1.23

Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion. Cancer Res (1996) 1.22

In vivo rodent erythrocyte micronucleus assay. Mutat Res (1994) 1.22

Therapeutic strategy for signet ring cell carcinoma of the stomach. Br J Surg (2004) 1.22

Plasminogen activator inhibitor-1 promotes angiogenesis by stimulating endothelial cell migration toward fibronectin. Cancer Res (2001) 1.21

Matrix metalloproteinases-2 and -9 are expressed in human neuroblastoma: contribution of stromal cells to their production and correlation with metastasis. Cancer Res (1998) 1.21

Cloning and expression of rat 25-hydroxyvitamin D3-1alpha-hydroxylase cDNA. Proc Natl Acad Sci U S A (1997) 1.20

A new human diploid cell strain, TIG-1, for the research on cellular aging. Exp Gerontol (1980) 1.18

An Arabidopsis sigma factor (SIG2)-dependent expression of plastid-encoded tRNAs in chloroplasts. Plant Cell Physiol (2001) 1.18

The gene encoding a calcium-dependent protein kinase located near the sbe1 gene encoding starch branching enzyme I is specifically expressed in developing rice seeds. Gene (1993) 1.18

Starch branching enzymes from immature rice seeds. J Biochem (1992) 1.18

Visualization of the metastatic process by green fluorescent protein expression. Anticancer Res (1997) 1.18

Extensor musculature of the cervical spine after laminoplasty: morphologic evaluation by coronal view of the magnetic resonance image. Spine (Phila Pa 1976) (2001) 1.17

Molecular analysis of the gene encoding a rice starch branching enzyme. Mol Gen Genet (1993) 1.16

Dynamic protein structures. Effects of pH on conformer stabilities at the ligand-binding site of bovine heart myoglobin carbonyl. J Biol Chem (1982) 1.15

Integrins alpha(v)beta3 and alpha(v)beta5 are expressed by endothelium of high-risk neuroblastoma and their inhibition is associated with increased endogenous ceramide. Cancer Res (2000) 1.13

Detection of JC virus in the brains of aged patients without progressive multifocal leukoencephalopathy by the polymerase chain reaction and Southern hybridization analysis. Neurosci Lett (1992) 1.13

Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism. J Biol Chem (1991) 1.13

Genetically fluorescent melanoma bone and organ metastasis models. Clin Cancer Res (1999) 1.12

Histopathology (International Neuroblastoma Pathology Classification) and MYCN status in patients with peripheral neuroblastic tumors: a report from the Children's Cancer Group. Cancer (2001) 1.11

Organochlorine pesticides and polychlorinated biphenyl residues in foodstuffs and human tissues from china: status of contamination, historical trend, and human dietary exposure. Arch Environ Contam Toxicol (2002) 1.11

Metastatic patterns of lung cancer visualized live and in process by green fluorescence protein expression. Clin Exp Metastasis (1997) 1.10

Production of the carotenoids lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis. Appl Environ Microbiol (1998) 1.09

Identification and light-induced expression of a novel gene of NADPH-protochlorophyllide oxidoreductase isoform in Arabidopsis thaliana. FEBS Lett (2000) 1.09

Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene. Cancer Res (1995) 1.08

A unique sequence located downstream from the rice mitochondrial atp6 may cause male sterility. Curr Genet (1994) 1.08

Hematin polymerization assay as a high-throughput screen for identification of new antimalarial pharmacophores. Antimicrob Agents Chemother (2000) 1.07

Sarcomas of the vagina and uterus: the Intergroup Rhabdomyosarcoma Study. J Pediatr Surg (1985) 1.07

Analysis of renal pathology and drug history in 158 Japanese patients with rheumatoid arthritis. Clin Nephrol (1998) 1.07

Expression of the puf operon in an aerobic photosynthetic bacterium, Roseobacter denitrificans. Plant Cell Physiol (1996) 1.07