Published in Cell on July 29, 1988
The structure of DNA in a nucleosome. Proc Natl Acad Sci U S A (1990) 2.85
Yeast alpha 2 repressor positions nucleosomes in TRP1/ARS1 chromatin. Mol Cell Biol (1990) 2.61
Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter. Mol Cell Biol (1991) 2.56
A transcriptionally active tRNA gene interferes with nucleosome positioning in vivo. Mol Cell Biol (1992) 1.47
Nucleosomes inhibit both transcriptional initiation and elongation by RNA polymerase III in vitro. EMBO J (1989) 1.44
Initiation of transcription on nucleosomal templates. Proc Natl Acad Sci U S A (1989) 1.40
DNA binding and gene regulation by the herpes simplex virus type 1 protein ICP4 and involvement of the TATA element. J Virol (1989) 1.27
A topological approach to nucleosome structure and dynamics: the linking number paradox and other issues. Biophys J (1998) 1.24
Differential binding of c-Myc and Max to nucleosomal DNA. Mol Cell Biol (1994) 1.19
Glucocorticoids locally disrupt an array of positioned nucleosomes on the rat tyrosine aminotransferase promoter in hepatoma cells. Proc Natl Acad Sci U S A (1990) 1.11
Effect of transcription of yeast chromatin on DNA topology in vivo. EMBO J (1990) 1.09
DNA-histone interactions are sufficient to position a single nucleosome juxtaposing Drosophila Adh adult enhancer and distal promoter. Nucleic Acids Res (1993) 1.08
Reconstitution of hyperacetylated, DNase I-sensitive chromatin characterized by high conformational flexibility of nucleosomal DNA. Proc Natl Acad Sci U S A (1998) 1.07
Modulation of the higher-order folding of chromatin by deletion of histone H3 and H4 terminal domains. Biochem J (1996) 1.06
Transcription termination and polyadenylation in retroviruses. Microbiol Rev (1993) 0.96
Hemimethylation of DNA prevents chromatin expression. Proc Natl Acad Sci U S A (1990) 0.95
Monte Carlo implementation of supercoiled double-stranded DNA. Biophys J (2000) 0.88
Alternative DNA-protein interactions in variable-length internucleosomal regions associated with Drosophila Adh distal promoter expression. Nucleic Acids Res (1990) 0.86
Archaeal chromatin: virtual or real? Proc Natl Acad Sci U S A (1997) 0.82
Linker histones' role revisited. Biophys J (1997) 0.77
Chromatin reconstituted from tandemly repeated cloned DNA fragments and core histones: a model system for study of higher order structure. Cell (1985) 4.27
Structure of the chromatosome, a chromatin particle containing 160 base pairs of DNA and all the histones. Biochemistry (1978) 4.20
Structural features of a phased nucleosome core particle. Proc Natl Acad Sci U S A (1983) 3.68
Cromatin and core particles formed from the inner histones and synthetic polydeoxyribonucleotides of defined sequence. Nucleic Acids Res (1979) 3.12
Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae. EMBO J (1991) 2.85
The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev (1994) 2.77
Mapping DNAase l-susceptible sites in nucleosomes labeled at the 5' ends. Cell (1976) 2.77
Nuclease digestion of circular TRP1ARS1 chromatin reveals positioned nucleosomes separated by nuclease-sensitive regions. J Mol Biol (1984) 2.65
Yeast alpha 2 repressor positions nucleosomes in TRP1/ARS1 chromatin. Mol Cell Biol (1990) 2.61
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLalpha. Mol Cell Biol (1998) 2.32
Two differentiable classes of metal atoms in alkaline phosphatase of Escherichia coli. Biochemistry (1968) 2.31
Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4. Genes Dev (1992) 2.28
Structure of chromatin containing extensively acetylated H3 and H4. Cell (1978) 2.17
Local protein-DNA interactions may determine nucleosome positions on yeast plasmids. Nature (1985) 2.08
Specific folding and contraction of DNA by histones H3 and H4. Cell (1977) 2.02
Core particle, fiber, and transcriptionally active chromatin structure. Annu Rev Cell Biol (1986) 1.96
Removal of histone H1 exposes a fifty base pair DNA segment between nucleosomes. Biochemistry (1976) 1.85
The organized chromatin domain of the repressed yeast a cell-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome. EMBO J (2000) 1.70
Cell type-specific chromatin organization of the region that governs directionality of yeast mating type switching. EMBO J (1997) 1.69
Circular dichroism of calf liver nucleohistone. Biochemistry (1970) 1.60
Chemical evidence that chromatin DNA exists as 160 base pair beads interspersed with 40 base pair bridges. Nucleic Acids Res (1976) 1.57
An alternating conformation characterizes the phosphodiester backbone of poly(dA-dT) in solution. J Biol Chem (1979) 1.56
The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae. J Biol Chem (1998) 1.52
Localization of the sites along nucleosome DNA which interact with NH2-terminal histone regions. J Biol Chem (1977) 1.51
Effects of sequence alterations in a DNA segment containing the 5 S RNA gene from Lytechinus variegatus on positioning of a nucleosome core particle in vitro. J Biol Chem (1985) 1.50
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa. Mol Cell Biol (1999) 1.48
Direct study of DNA-protein interactions in repressed and active chromatin in living cells. EMBO J (1996) 1.47
A transcriptionally active tRNA gene interferes with nucleosome positioning in vivo. Mol Cell Biol (1992) 1.47
Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure. EMBO J (1997) 1.43
Crosslinked histone octamer as a model of the nucleosome core. Proc Natl Acad Sci U S A (1977) 1.40
Effects of cycloheximide on chromatin biosynthesis. J Mol Biol (1975) 1.36
Preparation and physical characterization of a homogeneous population of monomeric nucleosomes from HeLa cells. Nucleic Acids Res (1976) 1.30
Positioned nucleosomes inhibit Dam methylation in vivo. Proc Natl Acad Sci U S A (1994) 1.23
Mechanism of a reversible, thermally induced conformational change in chromatin core particles. J Biol Chem (1979) 1.22
Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching. Genes Dev (1998) 1.21
Crystals of a nucleosome core particle containing defined sequence DNA. J Mol Biol (1988) 1.17
Isolation of an episomal yeast gene and replication origin as chromatin. Proc Natl Acad Sci U S A (1986) 1.17
A functional role of metal ions in a class II aldolase. Biochemistry (1969) 1.16
Yeast nucleosomes allow thermal untwisting of DNA. Nucleic Acids Res (1987) 1.15
Cloning, characterization and expression of the gene coding for a cytosine-5-DNA methyltransferase recognizing GpC. Nucleic Acids Res (1998) 1.14
Modulation of nucleosome structure by histone subtypes in sea urchin embryos. Proc Natl Acad Sci U S A (1981) 1.14
Nucleosomal location of the STE6 TATA box and Mat alpha 2p-mediated repression. Mol Cell Biol (1994) 1.14
Gal4p-mediated chromatin remodeling depends on binding site position in nucleosomes but does not require DNA replication. Mol Cell Biol (1998) 1.14
Resolution of a spectrum of nucleoprotein species in sonicated chromatin. Proc Natl Acad Sci U S A (1972) 1.11
A comparison of the proteins of condensed and extended chromatin fractions of rabbit liver and calf thymus. Biochemistry (1973) 1.09
Chromatin structure mapping in vivo using methyltransferases. Methods Enzymol (1996) 1.08
Alkaline phosphatase of Escherichia coli. Composition. Biochemistry (1968) 1.07
Molecular weight and subunit structure of delta-crystallin from embryonic chick lens fibers. Exp Eye Res (1974) 1.06
Iodocarboxypeptidase. Biochemistry (1966) 1.06
DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo. Nucleic Acids Res (1993) 1.06
Nucleosome positioning in vivo and in vitro. Bioessays (1986) 1.05
Yeast minichromosomes. Methods Cell Biol (1991) 1.02
Fractionation of chromatin components. Biochemistry (1972) 1.02
Conformation of DNA in chromatin core particles containing poly(dAdT)-poly(dAdT) studied by 31 P NMR spectroscopy. Nucleic Acids Res (1979) 1.02
Interaction of a repotter molecule with chromatin. Evidence suggesting that the proteins of chromatin do not occupy the minor groove of deoxyribonucleic acid. Biochemistry (1970) 1.01
Modification of chromatin by trypsin. The role of proteins in maintainance of deoxyribonucleic acid conformation. Biochemistry (1972) 1.00
Conformation of 145 base pair length poly (dG-dC) . poly (dG-dC) in solution and in association with histones. Nucleic Acids Res (1980) 1.00
Histones H3 and H4 interact with the ends of nucleosome DNA. Proc Natl Acad Sci U S A (1976) 1.00
Selective stimulation of nonhistone chromatin protein synthesis in lymphoid cells by phytohemagglutinin. Biochemistry (1973) 0.96
Histone compostion of chromatin subunits studied by immunosedimentation. Biochemistry (1976) 0.95
Isolation of yeast plasmid chromatin. Methods Enzymol (1989) 0.95
Negative homotropic interactions in binding of substrate to alkaline phosphatase of Escherichia coli. Biochemistry (1970) 0.95
Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene. EMBO J (2000) 0.94
Protein-DNA interactions in extended and condensed chromatin. Biochem Biophys Res Commun (1973) 0.94
Transient alterations of the chromatin structure of sea urchin early histone genes during embryogenesis. Nucleic Acids Res (1985) 0.94
Structure of sea urchin sperm chromatin core particle. J Biol Chem (1980) 0.91
Characterization of chromatin extensively substituted with 5-bromodeoxyuridine. Biochemistry (1974) 0.91
Zinc and cobalt alkaline phosphatases. Ann N Y Acad Sci (1969) 0.90
Sequence-specific interaction of histones with the simian virus 40 enhancer region in vitro. J Biol Chem (1985) 0.90
Random protection of single cut restriction endonuclease sites in SV40 mini-chromosomes assembled in vitro. FEBS Lett (1980) 0.89
Chromatin structure mapping in Saccharomyces cerevisiae in vivo with DNase I. Nucleic Acids Res (2001) 0.88
Circular dichroism spectra of putative transcribed and repressed chromatin. Biochem Biophys Res Commun (1973) 0.88
Modification of chromatin with acetic anhydride. Biochemistry (1971) 0.87
DNase-sensitive sites in nucleosomes. Their relative suspectibilities depend on nuclease used. J Biol Chem (1977) 0.87
Sequential chemical modifications of tyrosyl residues in alkaline phosphatase of Escherichia coli. Biochemistry (1971) 0.85
Protein kinase in HeLA nucleosomes: a reevaluation of the interactions of histomes with the ends of core particle DNA. Nucleic Acids Res (1978) 0.83
Distribution of RNA polymerase binding sites in fractionated chromatin. Proc Natl Acad Sci U S A (1974) 0.83
Structure and developmentally regulated expression of a Strongylocentrotus purpuratus collagen gene. Proc Natl Acad Sci U S A (1986) 0.81
Expression of a collagen gene in mesenchyme lineages of the Strongylocentrotus purpuratus embryo. Genes Dev (1988) 0.81
DNA methyltransferases as probes of chromatin structure in vivo. Methods Enzymol (1999) 0.81
Side-chain Cotton effects of ribonuclease. Biochemistry (1966) 0.81
Characterization of chromatin modified with ethyl acetimidate. Biochemistry (1977) 0.80
Partial dissociation and renaturation of embryonic chick delta-crystallin. Characterization by ultracentrifugation and circular dichroism. Biochim Biophys Acta (1977) 0.80
Modified curved DNA that could allow local DNA underwinding at the nucleosomal pseudodyad fails to position a nucleosome in vivo. Nucleic Acids Res (1995) 0.80
Distribution of satellite DNA in mouse liver chromatin fractionated by ECTHAM-cellulose chromatography. Biochem Biophys Res Commun (1975) 0.79
Structure and function of chromatin. Adv Enzymol Relat Areas Mol Biol (1973) 0.79
Kinetic properties of cobalt alkaline phosphatase. Biochemistry (1969) 0.79
The distribution of histones and nonhistone proteins in the ECTHAM-cellulose fractions of chromatin from several tissues. Eur J Biochem (1974) 0.79
Location of histone lysyl residues modified by in vitro acetylation of chromatin. Biochemistry (1979) 0.78
Quantitative immunochemical search for single stranded DNA in chromatin. Nat New Biol (1973) 0.78
Chromatin fractionation by chromatography on ECTHAM-cellulose. Methods Cell Biol (1977) 0.77
Isolation and characterization of spicule proteins from Strongylocentrotus purpuratus. Exp Cell Res (1986) 0.77
Histone-DNA interactions in chromatin core particles. Cold Spring Harb Symp Quant Biol (1978) 0.76
Rapid detection of functional expression of C-5-DNA methyltransferases in yeast. Nucleic Acids Res (1998) 0.75
Molecular homogeneity of the histone content of HeLa chromatin subunits. Biochemistry (1977) 0.75
Chromatin research surveyed: chromatin. Science (1989) 0.75
Role of metals in the class II aldolases. Spectral studies of cobalt yeast aldolase. Biochemistry (1971) 0.75
Ascorbate potentiates DNA damage by 1-methyl-1-nitrosourea in vivo and generates DNA strand breaks in vitro. Carcinogenesis (1987) 0.75
Fractionation of chromatin components. Farmaco Sci (1972) 0.75