The human growth hormone gene contains both positive and negative control elements.

PubWeight™: 1.11‹?› | Rank: Top 10%

🔗 View Article (PMID 3356677)

Published in J Biol Chem on April 15, 1988

Authors

L N Peritz1, E J Fodor, D W Silversides, P A Cattini, J D Baxter, N L Eberhardt

Author Affiliations

1: Metabolic Research Unit, University of California, San Francisco 94143.

Articles citing this

Human transcription factor USF stimulates transcription through the initiator elements of the HIV-1 and the Ad-ML promoters. EMBO J (1993) 2.45

Definition of the transcriptional activation domain of recombinant 43-kilodalton USF. Mol Cell Biol (1992) 1.31

Activation of the Epstein-Barr virus DNA polymerase promoter by the BRLF1 immediate-early protein is mediated through USF and E2F. J Virol (1996) 1.27

Cis- and trans-acting elements involved in amino acid regulation of asparagine synthetase gene expression. Mol Cell Biol (1993) 1.22

The helix-loop-helix containing transcription factor USF binds to and transactivates the promoter of the p53 tumor suppressor gene. Nucleic Acids Res (1993) 1.19

The helix-loop-helix transcription factor USF (upstream stimulating factor) binds to a regulatory sequence of the human insulin gene enhancer. Biochem J (1993) 1.06

Molecular and functional interactions of transcription factor USF with the long terminal repeat of human immunodeficiency virus type 1. J Virol (1995) 1.02

Stimulation of the adenovirus major late promoter in vitro by transcription factor USF is enhanced by the adenovirus DNA binding protein. J Virol (1994) 0.94

Xenopus TFIIIA gene transcription is dependent on cis-element positioning and chromatin structure. Mol Cell Biol (1998) 0.84

Single strand binding protein specific for the polyoma early-coding strand of PEA1 (AP1) regulatory sequence. Nucleic Acids Res (1991) 0.82

A negative regulatory element in the promoter of the human alpha 1-antitrypsin gene. Nucleic Acids Res (1989) 0.80

A nuclear single-stranded-DNA binding factor interacts with the long terminal repeats of the 1731 Drosophila retrotransposon. J Virol (1992) 0.80

An insulin-induced DNA-binding protein for the human growth hormone gene. J Clin Invest (1990) 0.80

A sequence-specific single-strand DNA binding protein that contacts repressor sequences in the human GM-CSF promoter. Nucleic Acids Res (1994) 0.79

Negative regulation of human growth hormone gene expression by insulin is dependent on hypoxia-inducible factor binding in primary non-tumor pituitary cells. J Biol Chem (2012) 0.78

Human chorionic somatomammotropin and growth hormone gene expression in rat pituitary tumour cells is dependent on proximal promoter sequences. Nucleic Acids Res (1989) 0.78

Lentiviral and Moloney retroviral expression of green fluorescent protein in somatotrophs in vivo. PLoS One (2013) 0.75

Articles by these authors

A method for isolation of intact, translationally active ribonucleic acid. DNA (1983) 13.67

Nucleotide sequence and amplification in bacteria of structural gene for rat growth hormone. Nature (1977) 7.97

Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science (1999) 6.02

Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev (1998) 5.28

A structural role for hormone in the thyroid hormone receptor. Nature (1995) 4.27

Human growth hormone: complementary DNA cloning and expression in bacteria. Science (1979) 3.67

Characterization of human prorenin expressed in mammalian cells from cloned cDNA. Proc Natl Acad Sci U S A (1986) 3.60

Construction and analysis of recombinant DNA for human chorionic somatomammotropin. Nature (1977) 3.13

Primary structure and evolution of rat growth hormone gene. Proc Natl Acad Sci U S A (1981) 2.80

Activation of a heterologous promoter in response to dexamethasone and cadmium by metallothionein gene 5'-flanking DNA. Cell (1984) 2.78

Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science (1988) 2.78

Glucocorticoid receptors: relations between steroid binding and biological effects. J Mol Biol (1972) 2.70

Regulation of growth hormone messenger RNA by thyroid and glucocorticoid hormones. Proc Natl Acad Sci U S A (1977) 2.47

Use of genotypic resistance testing to guide hiv therapy: clinical impact and cost-effectiveness. Ann Intern Med (2001) 2.47

Structure of cloned DNA complementary to rat prolactin messenger RNA. J Biol Chem (1980) 2.44

Specific cytoplasmic glucocorticoid hormone receptors in hepatoma tissue culture cells. Proc Natl Acad Sci U S A (1971) 2.35

Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science (1998) 2.31

The thyroid hormone receptor-beta-selective agonist GC-1 differentially affects plasma lipids and cardiac activity. Endocrinology (2000) 2.26

Human prolactin. cDNA structural analysis and evolutionary comparisons. J Biol Chem (1981) 2.19

Further evidence for posttranscriptional control of inducible tyrosine aminotransferase synthesis in cultured hepatoma cells. Nat New Biol (1972) 2.15

Conserved cysteine to serine mutation in tyrosinase is responsible for the classical albino mutation in laboratory mice. Nucleic Acids Res (1990) 2.13

Tissue effects of glucocorticoids. Am J Med (1972) 2.11

Role of DNA and specific cytoplasmic receptors in glucocorticoid action. Proc Natl Acad Sci U S A (1972) 1.97

Structure and evolution of the growth hormone gene family. Endocr Rev (1983) 1.97

Structural analysis of the prolactin gene suggests a separate origin for its 5' end. Nature (1982) 1.94

Molecular cloning of DNA complementary to bovine growth hormone mRNA. J Biol Chem (1980) 1.86

Genes for growth hormone, chorionic somatommammotropin, and growth hormones-like gene on chromosome 17 in humans. Science (1980) 1.85

Acute epiglottitis in children. Laryngoscope (1967) 1.83

Nucleotide sequence of part of the gene for human chorionic somatomammotropin: purification of DNA complementary to predominant mRNA species. Cell (1977) 1.81

Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene. Mol Cell Biol (1985) 1.78

Transcriptional activators differ in their responses to overexpression of TATA-box-binding protein. Mol Cell Biol (1995) 1.77

Structure of genes for human growth hormone and chorionic somatomammotropin. Proc Natl Acad Sci U S A (1979) 1.71

The relationship between glucocorticoid binding and tyrosine aminotransferase induction in hepatoma tissue culture cells. Proc Natl Acad Sci U S A (1970) 1.67

Analysis by immunocytochemistry and in situ hybridization of renin and its mRNA in kidney, testis, adrenal, and pituitary of the rat. Proc Natl Acad Sci U S A (1986) 1.62

Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells. J Biol Chem (1982) 1.62

Expression of cloned beta-endorphin gene sequences by Escherichia coli. Nature (1980) 1.59

Mechanism of resistance to steroids: glucocorticoid receptor defect in lymphoma cells. Nat New Biol (1972) 1.58

Glucocorticoid receptors in lymphoma cells in culture: relationship to glucocorticoid killing activity. Science (1971) 1.56

A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor. Chem Biol (1998) 1.55

Acute syphilitic meningitis in a man with seropositivity for human immunodeficiency virus infection and normal numbers of CD4 T lymphocytes. Arch Intern Med (1992) 1.55

eNOS gene transfer to vascular smooth muscle cells inhibits cell proliferation via upregulation of p27 and p21 and not apoptosis. Cardiovasc Res (2000) 1.53

Identification of a tumor necrosis factor-responsive element in the tumor necrosis factor alpha gene. J Biol Chem (1991) 1.52

Hypercalcemia of thyrotoxicosis. Ann Intern Med (1966) 1.52

Adipocyte macrophage colony-stimulating factor is a mediator of adipose tissue growth. J Clin Invest (1998) 1.51

Corticotropin and beta-endorphin: construction and analysis of recombinant DNA complementary to mRNA for the common precursor. Proc Natl Acad Sci U S A (1979) 1.49

The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs). Mol Endocrinol (2000) 1.46

Single dose streptozotocin-induced diabetes: considerations for study design in islet transplantation models. Lab Anim (2011) 1.43

Human trabecular cells. I. Establishment in tissue culture and growth characteristics. Invest Ophthalmol Vis Sci (1979) 1.43

Mechanism of glucocorticoid action: general features, with reference to steroid-mediated immunosuppression. Transplant Proc (1975) 1.42

Thyroid hormone receptors. Binding characteristics and lack of hormonal dependency for nuclear localization. J Biol Chem (1975) 1.42

Regulation of growth hormone gene expression: synergistic effects of thyroid and glucocorticoid hormones. Proc Natl Acad Sci U S A (1977) 1.35

Hormone receptors. N Engl J Med (1979) 1.34

Solubilized nuclear "receptors" for thyroid hormones. Physical characteristics and binding properties, evidence for multiple forms. J Biol Chem (1976) 1.34

Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophy. Circ Res (2001) 1.30

Steroid-induced nuclear binding of glucocorticoid receptors in intact hepatoma cells. J Mol Biol (1973) 1.29

Estradiol repression of tumor necrosis factor-alpha transcription requires estrogen receptor activation function-2 and is enhanced by coactivators. Proc Natl Acad Sci U S A (1999) 1.26

Extra-atrial expression of the gene for atrial natriuretic factor. Proc Natl Acad Sci U S A (1986) 1.25

Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis. Development (2000) 1.23

The nuclear hormone receptor gene superfamily. Annu Rev Med (1995) 1.23

Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice. Direct and indirect effects of angiotensin II on the heart. J Biol Chem (2001) 1.22

A filter assay for steroid hormone receptors. Biochemistry (1973) 1.21

Epidermal growth factor and expression of specific genes: effects on cultured rat pituitary cells are dissociable from the mitogenic response. Proc Natl Acad Sci U S A (1980) 1.21

Human islet amyloid polypeptide expression in COS-1 cells. A model of intracellular amyloidogenesis. Am J Pathol (1995) 1.20

Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. Science (1989) 1.19

Thyroid hormone receptors and responses. Recent Prog Horm Res (1979) 1.19

S20G mutant amylin exhibits increased in vitro amyloidogenicity and increased intracellular cytotoxicity compared to wild-type amylin. Am J Pathol (2000) 1.18

Hormone selectivity in thyroid hormone receptors. Mol Endocrinol (2001) 1.17

Highly specific transcription of globin sequences in isolated reticulocyte nuclei. Biochem Biophys Res Commun (1977) 1.17

Signaling pathways responsible for fetal gene induction in the failing human heart: evidence for altered thyroid hormone receptor gene expression. Circulation (2001) 1.17

Endonuclease S1-sensitive site in chicken pro-alpha 2(I) collagen 5' flanking gene region. Proc Natl Acad Sci U S A (1984) 1.13

Nuclear accumulation of epidermal growth factor in cultured rat pituitary cells. Nature (1980) 1.13

Interaction of thyroid and glucocorticoid hormones in rat pituitary tumor cells. Specificity and diversity of the responses analyzed by two-dimensional gel electrophoresis. J Biol Chem (1981) 1.12

Nerve growth factor induces the proto-oncogene c-jun in PC12 cells. J Biol Chem (1989) 1.12

Primary structure of the human renin gene. DNA (1984) 1.12

The human growth hormone gene locus: structure, evolution, and allelic variations. DNA (1987) 1.12

Transcription of two classes of rat growth hormone gene-associated repetitive DNA: differences in activity and effects of tandem repeat structure. Nucleic Acids Res (1984) 1.11

Cooperative binding of TEF-1 to repeated GGAATG-related consensus elements with restricted spatial separation and orientation. DNA Cell Biol (2000) 1.11

Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens. Mol Endocrinol (1990) 1.11

The developmental genetics of Hirschsprung's disease. Clin Genet (2012) 1.11

Most multifocal papillary thyroid carcinomas acquire genetic and morphotype diversity through subclonal evolution following the intra-glandular spread of the initial neoplastic clone. J Pathol (2008) 1.10

Early events in glucocorticoid action. Activation of the steroid receptor and its subsequent specific nuclear binding studied in a cell-free system. J Biol Chem (1973) 1.09

A novel assay in vitro of human islet amyloid polypeptide amyloidogenesis and effects of insulin secretory vesicle peptides on amyloid formation. Biochem J (1998) 1.09

Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptors. Mol Endocrinol (1992) 1.08

Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. Mol Endocrinol (2002) 1.08

Interaction of a tissue-specific factor with an essential rat growth hormone gene promoter element. Mol Cell Biol (1987) 1.08

Expression and regulation of transcripts encoding two members of the NR5A nuclear receptor subfamily of orphan nuclear receptors, steroidogenic factor-1 and NR5A2, in equine ovarian cells during the ovulatory process. Endocrinology (2000) 1.08

Synthesis of growth hormone by bacteria. Nature (1979) 1.07

The primary structure of coho salmon growth hormone and its cDNA. Gen Comp Endocrinol (1987) 1.07

Small heat shock proteins inhibit in vitro A beta(1-42) amyloidogenesis. FEBS Lett (1997) 1.07

TEF-1 transrepression in BeWo cells is mediated through interactions with the TATA-binding protein, TBP. J Biol Chem (1996) 1.07

Overexpression of FGF-2 increases cardiac myocyte viability after injury in isolated mouse hearts. Am J Physiol Heart Circ Physiol (2001) 1.06

The limits of the cellular capacity to mediate an estrogen response. Mol Endocrinol (1992) 1.06

Analysis of a major human chorionic somatomammotropin gene. Evidence for two functional promoter elements. J Biol Chem (1984) 1.06

Intracellular amyloidogenesis by human islet amyloid polypeptide induces apoptosis in COS-1 cells. Am J Pathol (1999) 1.06

Cloning of bovine prolactin cDNA and evolutionary implications of its sequence. DNA (1981) 1.06

High and low molecular weight fibroblast growth factor-2 increase proliferation of neonatal rat cardiac myocytes but have differential effects on binucleation and nuclear morphology. Evidence for both paracrine and intracrine actions of fibroblast growth factor-2. Circ Res (1996) 1.06

Molecular and structural biology of thyroid hormone receptors. Clin Exp Pharmacol Physiol Suppl (1998) 1.06