Published in Kokyu To Junkan on January 01, 1988
Helicobacter pylori infection and the development of gastric cancer. N Engl J Med (2001) 17.13
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett (1997) 11.19
Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med (2000) 5.02
Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53. EMBO J (1999) 4.69
Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD. Nat Neurosci (2000) 4.10
Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol Cell (2001) 3.56
Amino acid substitutions in a variant of IMP-1 metallo-beta-lactamase. Antimicrob Agents Chemother (2000) 3.03
Collection, storage, preservation, and normalization of human urinary exosomes for biomarker discovery. Kidney Int (2006) 3.00
Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase. Oncogene (2000) 2.84
Severe osteoporosis in mice lacking osteoclastogenesis inhibitory factor/osteoprotegerin. Biochem Biophys Res Commun (1998) 2.66
RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res Commun (1998) 2.62
Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells. Oncogene (2008) 2.47
Exosomal Fetuin-A identified by proteomics: a novel urinary biomarker for detecting acute kidney injury. Kidney Int (2006) 2.44
Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proc Natl Acad Sci U S A (1991) 2.26
Anchorage-independent cell growth signature identifies tumors with metastatic potential. Oncogene (2009) 1.99
Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes. FASEB J (2000) 1.93
Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates. J Biol Chem (2001) 1.89
A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers. Mol Cell Biol (1991) 1.89
Leucocyte movement and colchicine treatment in Behcet's disease. Lancet (1975) 1.83
Antibodies against GM1 ganglioside affect K+ and Na+ currents in isolated rat myelinated nerve fibers. Ann Neurol (1995) 1.80
C. elegans osm-3 gene mediating osmotic avoidance behaviour encodes a kinesin-like protein. Neuroreport (1993) 1.79
Retracted Regulation of APC activity by phosphorylation and regulatory factors. J Cell Biol (1999) 1.76
N-Terminally extended human ubiquitin-conjugating enzymes (E2s) mediate the ubiquitination of RING-finger proteins, ARA54 and RNF8. Eur J Biochem (2001) 1.76
A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase. Eur J Biochem (2000) 1.75
Modification of cullin-1 by ubiquitin-like protein Nedd8 enhances the activity of SCF(skp2) toward p27(kip1). Biochem Biophys Res Commun (2000) 1.68
Bone morphogenetic protein 2 stimulates osteoclast differentiation and survival supported by receptor activator of nuclear factor-kappaB ligand. Endocrinology (2001) 1.66
Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures. Biochem Biophys Res Commun (1998) 1.63
In vitro phosphorylation of the tumor suppressor gene RB protein by mitosis-specific histone H1 kinase. Biochem Biophys Res Commun (1989) 1.62
Osteoprotegerin produced by osteoblasts is an important regulator in osteoclast development and function. Endocrinology (2000) 1.61
In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. Biochem Biophys Res Commun (1999) 1.61
Degradation of human Aurora2 protein kinase by the anaphase-promoting complex-ubiquitin-proteasome pathway. Oncogene (2000) 1.54
AP214, an analogue of alpha-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality. Kidney Int (2008) 1.54
Diabetic lipemia with maturity-onset diabetes of the young. Intern Med (1997) 1.49
An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530). Cell Death Dis (2013) 1.49
Transforming growth factor beta affects osteoclast differentiation via direct and indirect actions. J Bone Miner Res (2001) 1.47
Identification of ubiquitinated histones 2A and 2B in Physarum polycephalum. Disappearance of these proteins at metaphase and reappearance at anaphase. J Biol Chem (1985) 1.47
Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis. Kidney Int (2006) 1.46
Right sylvian fissure subarachnoid hemorrhage has electrocardiographic consequences. Stroke (2001) 1.45
Characterization of a novel mammalian SUMO-1/Smt3-specific isopeptidase, a homologue of rat axam, which is an axin-binding protein promoting beta-catenin degradation. J Biol Chem (2001) 1.40
The Fermi Gamma-Ray Space Telescope discovers the pulsar in the young galactic supernova remnant CTA 1. Science (2008) 1.39
Identification of an ovarian clear cell carcinoma gene signature that reflects inherent disease biology and the carcinogenic processes. Oncogene (2010) 1.39
Association of tetra-amelia, ectodermal dysplasia, hypoplastic lacrimal ducts and sacs opening towards the exterior, peculiar face, and developmental retardation. J Med Genet (1987) 1.38
Identity of a tumor cytotoxic factor from human fibroblasts and hepatocyte growth factor. Biochem Biophys Res Commun (1990) 1.37
Osteoclast differentiation factor mediates an essential signal for bone resorption induced by 1 alpha,25-dihydroxyvitamin D3, prostaglandin E2, or parathyroid hormone in the microenvironment of bone. Biochem Biophys Res Commun (1998) 1.33
Determination of anaerobic threshold for assessment of functional state in patients with chronic heart failure. Circulation (1983) 1.25
Characterization of a temperature-sensitive mutant of mouse FM3A cells defective in DNA replication. Proc Natl Acad Sci U S A (1985) 1.25
Fission yeast Cut2 required for anaphase has two destruction boxes. EMBO J (1997) 1.24
p13suc1 suppresses the catalytic function of p34cdc2 kinase for intermediate filament proteins, in vitro. J Biol Chem (1992) 1.24
Effect of protonation on the isomerization properties of n-butylamine Schiff base of isomeric retinal as revealed by direct HPLC analyses: selection of isomerization pathways by retinal proteins. Photochem Photobiol (1991) 1.23
Butyrolactone I, a selective inhibitor of cdk2 and cdc2 kinase. Oncogene (1993) 1.20
A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase. Genes Dev (2000) 1.19
An immunohistochemical study of the apocrine type of cutaneous mixed tumors with special reference to their follicular and sebaceous differentiation. J Cutan Pathol (1999) 1.15
Age associated axonal features in HNPP with 17p11.2 deletion in Japan. J Neurol Neurosurg Psychiatry (2005) 1.15
Establishment and characterization of an immortal macrophage-like cell line inducible to differentiate to osteoclasts. Biochem Biophys Res Commun (1998) 1.14
Activity of the carbapenem panipenem and role of the OprD (D2) protein in its diffusion through the Pseudomonas aeruginosa outer membrane. Antimicrob Agents Chemother (1993) 1.13
Percutaneous ethanol injection in the treatment of liver neoplasms. AJR Am J Roentgenol (1987) 1.13
Increase in intracellular Ca(2+) and calcitonin gene-related peptide release through metabotropic P2Y receptors in rat dorsal root ganglion neurons. Neuroscience (2002) 1.12
Increased arterial wall stiffness limits flow volume in the lower extremities in type 2 diabetic patients. Diabetes Care (2001) 1.11
Mechanisms for development of functional tricuspid regurgitation determined by pulsed Doppler and two-dimensional echocardiography. Am J Cardiol (1984) 1.11
The cell cycle regulator, human p50weel, is a tyrosine kinase and not a serine/tyrosine kinase. Biochem Biophys Res Commun (1992) 1.09
Dephosphorylation of human p34cdc2 kinase on both Thr-14 and Tyr-15 by human cdc25B phosphatase. FEBS Lett (1993) 1.07
A central nervous system action of nitric oxide in blood pressure regulation. J Pharmacol Exp Ther (1992) 1.07
Capillary number and percentage closed in human diabetic sural nerve. Proc Natl Acad Sci U S A (1985) 1.07
The G protein beta5 subunit interacts selectively with the Gq alpha subunit. J Biol Chem (1998) 1.07
1H- and 31P-magnetic resonance spectroscopy and imaging as a new diagnostic tool to evaluate neuropathic foot ulcers in Type II diabetic patients. Diabetologia (2000) 1.06
Postprandial plasma gastrin and secretin concentrations after a pancreatoduodenectomy. A comparison between a pylorus-preserving pancreatoduodenectomy and the Whipple procedure. Ann Surg (1989) 1.05
Role of host and bacterial factors in modulating staphylococcal adhesion to implanted polymer surfaces. J Biomater Appl (1990) 1.05
Abnormalities of endoneurial microvessels and sural nerve pathology in diabetic neuropathy. Neurology (1987) 1.05
Non-invasive ultrasonic measurement of the elastic properties of the human abdominal aorta. Cardiovasc Res (1986) 1.03
A protein which facilitates assembly of nucleosome-like structures in vitro in mammalian cells. J Biochem (1983) 1.02
Role of the increase in p21 in cisplatin-induced acute renal failure in rats. J Am Soc Nephrol (2001) 1.02
Lancefield group C Streptococcus dysgalactiae infection responsible for fish mortalities in Japan. J Fish Dis (2004) 1.01
cdc2 kinase-mediated phosphorylation of splicing factor SF2/ASF. Biochem Biophys Res Commun (1998) 1.01
Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis. Gut (2003) 1.01
A temperature-sensitive mutant of cultured mouse cells defective in chromosome condensation. Exp Cell Res (1980) 1.01
Endothelin-1 induces cyclooxygenase-2 expression via nuclear factor of activated T-cell transcription factor in glomerular mesangial cells. J Am Soc Nephrol (2001) 1.00
Brain-derived neurotrophic factor prevents low-frequency inputs from inducing long-term depression in the developing visual cortex. J Neurosci (1999) 1.00
Caries inhibitory activity of cacao bean husk extract in in-vitro and animal experiments. Arch Oral Biol (2000) 1.00
Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis-inhibitory factor. Eur J Biochem (1998) 0.98
High prevalence of herpes simplex virus type 2 in acute retinal necrosis syndrome associated with herpes simplex virus in Japan. Am J Ophthalmol (2000) 0.98
Evidence for the involvement of H1 histone phosphorylation in chromosome condensation. Nature (1980) 0.98
Regulation of gene expression of proteasomes (multi-protease complexes) during growth and differentiation of human hematopoietic cells. J Biol Chem (1992) 0.98
Porphyromonas gingivalis fimbrillin is one of the fibronectin-binding proteins. Infect Immun (1996) 0.98
A single intraportal administration of follistatin accelerates liver regeneration in partially hepatectomized rats. Gastroenterology (1995) 0.97
Differential occurrence of CSF-like activity and transforming activity of Mos during the cell cycle in fibroblasts. EMBO J (1992) 0.97
14-3-3 zeta protein binds to the carboxyl half of mouse wee1 kinase. Biochem Biophys Res Commun (1997) 0.97
Expression of a dominant negative SHP-2 in transgenic mice induces insulin resistance. J Biol Chem (1999) 0.97
Intramedullary spinal teratoma with spina bifida. Childs Nerv Syst (2001) 0.96
In vitro and in vivo antibacterial activities of CS-834, a novel oral carbapenem. Antimicrob Agents Chemother (1997) 0.96
Differential activity of the G protein beta5 gamma2 subunit at receptors and effectors. J Biol Chem (1998) 0.96
Vanadate triggers the transition from chromosome condensation to decondensation in a mitotic mutant (tsTM13) inactivation of p34cdc2/H1 kinase and dephosphorylation of mitosis-specific histone H3. Eur J Biochem (1996) 0.96
Antibacterial trichorabdal diterpenes from Rabdosia trichocarpa. Phytochemistry (1994) 0.95
Tetrodotoxin-resistant sodium channels of dorsal root ganglion neurons are readily activated in diabetic rats. Neuroscience (1999) 0.95
Observations on the mechanism of renin release by catecholamines. Circ Res (1970) 0.95
RNA-primed initiation sites of DNA replication in the origin region of bacteriophage lambda genome. Nucleic Acids Res (1988) 0.95
Real-time observation of a single DNA digestion by lambda exonuclease under a fluorescence microscope field. Nucleic Acids Res (2001) 0.95