Published in Drug Metab Dispos on May 25, 1976
Relationship between the genetically determined acetylator phenotype and DNA damage induced by hydralazine and 2-aminofluorene in cultured rabbit hepatocytes. Proc Natl Acad Sci U S A (1982) 0.81
N-acetylation of drugs. Observations on the properties of partially purified N-acetyltransferase from peripheral blood of rabbit. Biochem J (1980) 0.77
The Lambeth Conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc Res (1988) 3.98
Nomenclature for N-acetyltransferases. Pharmacogenetics (1995) 3.59
N-acetylation pharmacogenetics. Pharmacol Rev (1985) 2.63
Myocardial ischaemia: can we agree on a definition for the 21st century? Cardiovasc Res (1994) 2.16
Suppression of bilirubin production in the Crigler-Najjar type I syndrome: studies with the heme oxygenase inhibitor tin-mesoporphyrin. Pediatrics (1992) 2.14
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation. Proc Natl Acad Sci U S A (1981) 2.04
Reperfusion-induced arrhythmias: mechanisms and prevention. J Mol Cell Cardiol (1984) 2.00
Clinical pharmacokinetics of isoniazid. Clin Pharmacokinet (1980) 1.97
The oxygen paradox and the calcium paradox: two facets of the same problem? J Mol Cell Cardiol (1978) 1.95
Species variation in the coronary collateral circulation during regional myocardial ischaemia: a critical determinant of the rate of evolution and extent of myocardial infarction. Cardiovasc Res (1987) 1.83
Abrupt reoxygenation of the anoxic potassium-arrested perfused rat heart: a study of myocardial enzyme release. J Mol Cell Cardiol (1973) 1.77
Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy. Circ Res (1987) 1.74
Reperfusion of the ischemic myocardium. J Mol Cell Cardiol (1977) 1.74
Formation of 4-hydroxy-2-nonenal-modified proteins in ischemic rat heart. Am J Physiol (1999) 1.61
Ischemic contracture of the myocardium: mechanisms and prevention. Am J Cardiol (1977) 1.61
Purification, physicochemical, and kinetic properties of liver acetyl-CoA:arylamine N-acetyltransferase from rapid acetylator rabbits. Mol Pharmacol (1987) 1.60
Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with "anti-free radical" interventions and a free radical-generating system in the isolated perfused rat heart. Circ Res (1986) 1.52
The influence of some physico-chemical factors on the biliary excretion of a series of structurally related aryl sulphate esters. Biochem Pharmacol (1969) 1.51
Oxygen deprivation and early myocardial contractile failure: a reassessment of the possible role of adenosine triphosphate. Am J Cardiol (1979) 1.48
The antiarrhythmic action of ischaemic preconditioning in rat hearts does not involve functional Gi proteins. Cardiovasc Res (1993) 1.46
Control of hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient newborns using an inhibitor of bilirubin production, Sn-mesoporphyrin. Pediatrics (1998) 1.44
Protection of the immature myocardium during global ischemia. A comparison of four clinical cardioplegic solutions in the rabbit heart. J Thorac Cardiovasc Surg (1989) 1.43
Optimal myocardial protection during crystalloid cardioplegia. Interrelationship between volume and duration of infusion. J Thorac Cardiovasc Surg (1988) 1.43
Diverse point mutations in the human gene for polymorphic N-acetyltransferase. Proc Natl Acad Sci U S A (1991) 1.42
Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol. Circ Res (1984) 1.39
Harvesting hearts for long-term preservation. Detrimental effects of initial hypothermic infusion of cardioplegic solutions. J Thorac Cardiovasc Surg (1990) 1.38
Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. Science (1982) 1.36
Preconditioning of ischemic myocardium: reperfusion-induced arrhythmias. Am J Physiol (1987) 1.35
The isolated blood and perfusion fluid perfused heart. Pharmacol Res (2000) 1.34
Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion? Acta Physiol Scand Suppl (1986) 1.26
Control of heme oxygenase and plasma levels of bilirubin by a synthetic heme analogue, tin-protoporphyrin. Hepatology (1984) 1.26
Hypothermic arrest and potassium arrest: metabolic and myocardial protection during elective cardiac arrest. Circ Res (1975) 1.25
Survival and the sex ratio in trisomy 17-18. Am J Hum Genet (1967) 1.25
Tissue distribution and disposition of tin-protoporphyrin, a potent competitive inhibitor of heme oxygenase. J Pharmacol Exp Ther (1984) 1.24
Ischaemia-induced and reperfusion-induced arrhythmias differ in their sensitivity to potassium: implications for mechanisms of initiation and maintenance of ventricular fibrillation. J Mol Cell Cardiol (1989) 1.23
Control of heme metabolism with synthetic metalloporphyrins. J Clin Invest (1986) 1.23
The role of glucose in the survival and 'recovery' of the anoxic isolated perfused rat heart. Biochem J (1972) 1.20
Genetic variation in N-acetylation of carcinogenic arylamines by human and rabbit liver. Mol Pharmacol (1978) 1.19
Tin-protoporphyrin suppression of hyperbilirubinemia in mutant mice with severe hemolytic anemia. Blood (1983) 1.15
The "border zone" in evolving myocardial infarction: controversy or confusion? Am J Cardiol (1981) 1.14
Reduction of the C2 and C4 vinyl groups of Sn-protoporphyrin to form Sn-mesoporphyrin markedly enhances the ability of the metalloporphyrin to inhibit in vivo heme catabolism. Arch Biochem Biophys (1987) 1.14
Coronary vascular responsiveness to 5-hydroxytryptamine before and after infusion of hyperkalemic crystalloid cardioplegic solution in the rat heart. Possible evidence of endothelial damage. J Thorac Cardiovasc Surg (1989) 1.13
Pharmacogenetics of the arylamine N-acetyltransferases: a symposium in honor of Wendell W. Weber. Drug Metab Dispos (2000) 1.12
Multiple N-acetyltransferases and drug metabolism. Tissue distribution, characterization and significance of mammalian N-acetyltransferase. Biochem J (1973) 1.12
A rapid, simple acetaminophen spectrophotometric determination. Pediatrics (1979) 1.12
Creatine kinase isoenzymes: their separation and quantitation. Cardiovasc Res (1977) 1.12
A filter paper method for determining isoniazid acetylator phenotype. Am J Hum Genet (1974) 1.12
Isolation and properties of aromatic alpha-keto acid reductase. J Biol Chem (1966) 1.10
Control of severe hyperbilirubinemia in full-term newborns with the inhibitor of bilirubin production Sn-mesoporphyrin. Pediatrics (1999) 1.09
Myocardial protection during ischemic cardiac arrest. A possible hazard with calcium-free cardioplegic infusates. J Thorac Cardiovasc Surg (1977) 1.09
Manganese and zinc blockade of enzyme induction: studies with microsomal heme oxygenase. Proc Natl Acad Sci U S A (1979) 1.09
Free radicals and reperfusion-induced arrhythmias: protection by spin trap agent PBN in the rat heart. Circ Res (1987) 1.08
Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart. Cardiovasc Res (1993) 1.08
Regulation of sarcolemmal Na(+)/H(+) exchanger activity by angiotensin II in adult rat ventricular myocytes: opposing actions via AT(1) versus AT(2) receptors. Circ Res (1999) 1.07
Sn-protoporphyrin use in the management of hyperbilirubinemia in term newborns with direct Coombs-positive ABO incompatibility. Pediatrics (1988) 1.07
Direct comparison of Sn-mesoporphyrin, an inhibitor of bilirubin production, and phototherapy in controlling hyperbilirubinemia in term and near-term newborns. Pediatrics (1995) 1.07
An experimental model of postnatal jaundice in the suckling rat. Suppression of induced hyperbilirubinemia by Sn-protoporphyrin. J Clin Invest (1984) 1.06
Ultrastructural damage associated with reoxygenation of the anoxic myocardium. J Mol Cell Cardiol (1975) 1.06
Structural heterogeneity of Caucasian N-acetyltransferase at the NAT1 gene locus. Arch Biochem Biophys (1993) 1.05
Studies on the mechanism of Sn-protoporphyrin suppression of hyperbilirubinemia. Inhibition of heme oxidation and bilirubin production. J Clin Invest (1985) 1.05
Suppression of hyperbilirubinemia in the rat neonate by chromium-protoporphyrin. Interactions of metalloporphyrins with microsomal heme oxygenase of human spleen. J Exp Med (1982) 1.05
On the active site of liver acetyl-CoA. Arylamine N-acetyltransferase from rapid acetylator rabbits (III/J). J Biol Chem (1988) 1.04
Immunochemical studies of rabbit N-acetyltransferases. Mol Pharmacol (1980) 1.04
Reperfusion-induced arrhythmias are critically dependent upon occluded zone size: relevance to the mechanism of arrhythmogenesis. J Mol Cell Cardiol (1989) 1.04
N-acetylation of drugs: isolation and properties of an N-acetyltransferase from rabbit liver. Mol Pharmacol (1967) 1.03
The liver excretes large amounts of heme into bile when heme oxygenase is inhibited competitively by Sn-protoporphyrin. Proc Natl Acad Sci U S A (1985) 1.03
Cellular protection during myocardial ischemia: the development and characterization of a procedure for the induction of reversible ischemic arrest. Circulation (1976) 1.03
The cytochrome P-450-depleted animal: an experimental model for in vivo studies in chemical biology. Proc Natl Acad Sci U S A (1982) 1.03
Zinc porphyrins: potent inhibitors of hematopoieses in animal and human bone marrow. Proc Natl Acad Sci U S A (1997) 1.02
Enzyme release during myocardial anoxia: a study of metabolic protection. J Mol Cell Cardiol (1975) 1.01
Ischemia-induced and reperfusion-induced arrhythmias: importance of heart rate. Am J Physiol (1989) 1.00
Porphyrogenic effects and induction of heme oxygenase in vivo by delta-aminolevulinic acid. Biochim Biophys Acta (1981) 1.00
Simultaneous measurement of chloramphenicol and chloramphenicol succinate by high-performance liquid chromatography. J Chromatogr (1980) 1.00
Recovery from cardiac bypass and elective cardiac arrest. The metabolic consequences of various cardioplegic procedures in the isolated rat heart. Circ Res (1974) 0.99
The calcium paradox: metabolic, electrophysiological, contractile and ultrastructural characteristics in four species. Eur J Cardiol (1978) 0.99
Characterization of naturally occurring and recombinant human N-acetyltransferase variants encoded by NAT1. Mol Pharmacol (2000) 0.98
Heme oxygenase: a target gene for anti-diabetic and obesity. Curr Pharm Des (2008) 0.98
Pharmacokinetics of chloramphenicol and chloramphenicol succinate in infants and children. J Pediatr (1981) 0.98
Cold cardioplegia or continuous coronary perfusion? Report on preliminary clinical experience as assessed cytochemically. J Thorac Cardiovasc Surg (1977) 0.98
Substrate selectivity of mouse N-acetyltransferases 1, 2, and 3 expressed in COS-1 cells. Drug Metab Dispos (1998) 0.97
Myocardial protection during ischemic cardiac arrest. The importance of magnesium in cardioplegic infusates. J Thorac Cardiovasc Surg (1978) 0.97
Temporal and spatial characteristics of evolving cell injury during regional myocardial ischemia in the dog: the "border zone" controversy. J Am Coll Cardiol (1983) 0.96
Metal ion interactions in the control of haem oxygenase induction in liver and kidney. Biochem J (1980) 0.96
Control of heme and cytochrome P-450 metabolism by inorganic metals, organometals and synthetic metalloporphyrins. Environ Health Perspect (1984) 0.96
Brain death-induced impairment of cardiac contractile performance can be reversed by explantation and may not preclude the use of hearts for transplantation. Circ Res (1992) 0.96
Simultaneous measurements of acetaminophen and salicylate in plasma by liquid chromatography. Clin Chem (1979) 0.95
Genetic control of acetyl coenzyme A-dependent arylamine N-acetyltransferase, hydrazine N-acetyltransferase, and N-hydroxy-arylamine O-acetyltransferase enzymes in C57BL/6J, A/J, AC57F1, and the rapid and slow acetylator A.B6 and B6.A congenic inbred mouse. Drug Metab Dispos (1988) 0.95
Sustained limitation of myocardial necrosis 24 hours after coronary artery occlusion: verapamil infusion in dogs with small myocardial infarcts. Am J Cardiol (1983) 0.94
Downregulation of the human heme oxygenase gene by glucocorticoids and identification of 56b regulatory elements. Biochem Biophys Res Commun (1996) 0.94
The mechanism of isoniazid acetylation by human N-acetyltransferase. Biochim Biophys Acta (1968) 0.94
Control of jaundice in preterm newborns by an inhibitor of bilirubin production: studies with tin-mesoporphyrin. Pediatrics (1994) 0.94
Developments in cardioprotection: "polarized" arrest as an alternative to "depolarized" arrest. Ann Thorac Surg (1999) 0.94
Xanthine oxidase is not a source of free radicals in the ischemic rabbit heart. J Mol Cell Cardiol (1987) 0.94
Diabetes and the survival and recovery of the anoxic myocardium. J Mol Cell Cardiol (1975) 0.94
The metabolic fate and elimination of streptozotocin. Biochem Soc Trans (1975) 0.94
Verapamil and the calcium paradox. J Mol Cell Cardiol (1980) 0.93
"Dose"-dependency and temporal characteristics of protection by ischaemic preconditioning against ischaemia-induced arrhythmias in rat hearts. J Mol Cell Cardiol (1993) 0.93
Purification and properties of N-acetyltransferase from mammalian liver. Ann N Y Acad Sci (1968) 0.93
The temperature dependence of the calcium paradox: enzymatic, functional and morphological correlates of cellular injury. J Mol Cell Cardiol (1983) 0.92