Published in Gene on January 01, 1986
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Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast. Proc Natl Acad Sci U S A (1993) 3.39
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Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin. Nature (1981) 2.97
Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site. Proc Natl Acad Sci U S A (1989) 2.92
A sensitive new prenatal test for sickle-cell anemia. N Engl J Med (1982) 2.91
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The nucleotide sequences of the untranslated 5' regions of human alpha- and beta-globin mRNAs. Proc Natl Acad Sci U S A (1977) 2.75
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Construction of a functional human suppressor tRNA gene: an approach to gene therapy for beta-thalassaemia. Nature (1982) 2.65
Cloning and complete nucleotide sequence of human 5'-alpha-globin gene. Proc Natl Acad Sci U S A (1980) 2.62
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Gene deletions in patients with haemophilia B and anti-factor IX antibodies. Nature (1983) 2.59
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Molecular cloning of the gene for human anti-haemophilic factor IX. Nature (1982) 2.50
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Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA. Proc Natl Acad Sci U S A (1985) 2.44
Two different molecular organizations account for the single alpha-globin gene of the alpha-thalassemia-2 genotype. J Clin Invest (1980) 2.38
Organization of the alpha-globin genes in the Chinese alpha-thalassemia syndromes. J Clin Invest (1979) 2.37
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alpha-Globin gene organisation in blacks precludes the severe form of alpha-thalassaemia. Nature (1979) 2.25
Chromosome mapping and expression of a putative testis-determining gene in mouse. Science (1989) 2.22
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A functional marker centromere with no detectable alpha-satellite, satellite III, or CENP-B protein: activation of a latent centromere? Am J Hum Genet (1993) 2.03
Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice. EMBO J (1998) 1.97
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A rapid screening test for antenatal sex determination. Lancet (1984) 1.92
Isolation of cDNA encoding the human NF-E2 protein. Proc Natl Acad Sci U S A (1993) 1.91
Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice. Proc Natl Acad Sci U S A (1993) 1.88
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc Natl Acad Sci U S A (1993) 1.88
Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death. Proc Natl Acad Sci U S A (1998) 1.86
A distant gene deletion affects beta-globin gene function in an atypical gamma delta beta-thalassemia. J Clin Invest (1985) 1.85
Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia. N Engl J Med (1982) 1.85
Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice. Proc Natl Acad Sci U S A (1992) 1.84
Construction of human chromosome 21-specific yeast artificial chromosomes. Proc Natl Acad Sci U S A (1989) 1.83
High-resolution chromosome sorting and DNA spot-blot analysis assign McArdle's syndrome to chromosome 11. Science (1984) 1.80
Prenatal diagnosis of beta-thalassaemia and sickle-cell anaemia. Experience with 24 cases. Lancet (1977) 1.77
Comparative chromosome mapping of a conserved homoeo box region in mouse and human. Nature (1985) 1.77
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition. Cell Death Differ (2011) 1.77
Authentic beta-globin mRNA sequences in homozygous betaO-thalassemia. Proc Natl Acad Sci U S A (1977) 1.75
A novel chromatin immunoprecipitation and array (CIA) analysis identifies a 460-kb CENP-A-binding neocentromere DNA. Genome Res (2001) 1.75
The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts. J Biol Chem (1999) 1.69
Intracavernosal vascular endothelial growth factor (VEGF) injection and adeno-associated virus-mediated VEGF gene therapy prevent and reverse venogenic erectile dysfunction in rats. Int J Impot Res (2003) 1.68
Centromere protein B null mice are mitotically and meiotically normal but have lower body and testis weights. J Cell Biol (1998) 1.68
The testis-specific phosphoglycerate kinase gene pgk-2 is a recruited retroposon. Mol Cell Biol (1987) 1.67
Assignment of human beta-, gamma-, and delta-globin genes to the short arm of chromosome 11 by chromosome sorting and DNA restriction enzyme analysis. Proc Natl Acad Sci U S A (1979) 1.67
Molecular characterization of de novo secondary trisomy 13. Am J Hum Genet (1994) 1.66
A 330 kb CENP-A binding domain and altered replication timing at a human neocentromere. EMBO J (2001) 1.65
Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins. Hum Mol Genet (2000) 1.63
Prenatal diagnosis of hemoglobin disorders. Prog Hematol (1977) 1.61
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Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice. Hum Mol Genet (1999) 1.59
Mild thalassemia: the result of interactions of alpha and beta thalassemia genes. J Clin Invest (1970) 1.59
Molecular isolation and characterization of an expressed gene from the human Y chromosome. Hum Mol Genet (1992) 1.56
Prenatal diagnosis of hemoglobin H disease. J Pediatr (1978) 1.55
Adeno-associated viral vector-mediated vascular endothelial growth factor gene transfer induces neovascular formation in ischemic heart. Proc Natl Acad Sci U S A (2000) 1.50
Tissue- and development-specific alternative RNA splicing regulates expression of multiple isoforms of erythroid membrane protein 4.1. J Biol Chem (1991) 1.50
Multiple protein 4.1 isoforms produced by alternative splicing in human erythroid cells. Proc Natl Acad Sci U S A (1988) 1.49
Mouse major (gamma) satellite DNA is highly conserved and organized into extremely long tandem arrays: implications for recombination between nonhomologous chromosomes. Genomics (1989) 1.47
The molecular defects of alpha-thalassemia in the Filipino. Hemoglobin (1977) 1.47
Diagnosis of homozygous alpha-thalassemia in cultured amniotic-fluid fibroblasts. N Engl J Med (1978) 1.46
cDNA sequence for human erythrocyte ankyrin. Proc Natl Acad Sci U S A (1990) 1.46
Initiation codon mutation as a cause of alpha thalassemia. J Biol Chem (1984) 1.45
Improving feasibility of posterior descending coronary artery flow recording by transthoracic Doppler echocardiography. Eur J Echocardiogr (2003) 1.45
Sequence analysis of an 80 kb human neocentromere. Hum Mol Genet (1999) 1.45
Direct isolation of the functional human thymidine kinase gene with a cosmid shuttle vector. Proc Natl Acad Sci U S A (1984) 1.45
HZwint-1, a novel human kinetochore component that interacts with HZW10. J Cell Sci (2000) 1.44
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Hospital use of acid-suppressive medications and its fall-out on prescribing in general practice: a 1-month survey. Aliment Pharmacol Ther (2003) 1.40