Published in Diabetologia on May 01, 1978
Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell. J Cell Biol (1984) 1.21
The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide. Biochem J (1988) 0.98
Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells. Biochem J (1984) 0.85
A Global Approach for Quantitative Super Resolution and Electron Microscopy on Cryo and Epoxy Sections Using Self-labeling Protein Tags. Sci Rep (2017) 0.75
Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology (1992) 5.45
Heterogeneous distribution of filipin--cholesterol complexes across the cisternae of the Golgi apparatus. Proc Natl Acad Sci U S A (1981) 2.45
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development (1991) 2.28
Mammalian Sec23p homologue is restricted to the endoplasmic reticulum transitional cytoplasm. Proc Natl Acad Sci U S A (1991) 2.27
Unique and shared functions of different connexins in mice. Curr Biol (2000) 2.10
Connexin40 regulates renin production and blood pressure. Kidney Int (2007) 1.91
Heterogeneity and contact-dependent regulation of hormone secretion by individual B cells. Exp Cell Res (1986) 1.80
Stimulation of insulin secretion reveals heterogeneity of pancreatic B cells in vivo. J Clin Invest (1987) 1.80
Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin. Diabetes (2000) 1.71
Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells. Diabetologia (2008) 1.64
Expression of connexin36 in the adult and developing rat brain. Brain Res (2000) 1.62
The possible importance of contact between pancreatic islet cells for the control of insulin release. Endocrinology (1982) 1.55
The topography of electrical synchrony among beta-cells in the mouse islet of Langerhans. Q J Exp Physiol (1984) 1.47
Homologous but not heterologous contact increases the insulin secretion of individual pancreatic B-cells. Exp Cell Res (1989) 1.38
Direct identification of electrophysiologically monitored cells within intact mouse islets of Langerhans. Diabetes (1986) 1.29
Subcellular distribution and function of Rab3A, B, C, and D isoforms in insulin-secreting cells. Mol Endocrinol (1999) 1.27
Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance. J Clin Invest (2000) 1.23
Cx36 preferentially connects beta-cells within pancreatic islets. Diabetes (2000) 1.22
Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion. J Cell Biol (1979) 1.21
Islet-cell-to-cell communication as basis for normal insulin secretion. Diabetes Obes Metab (2007) 1.16
B-cell size influences glucose-stimulated insulin secretion. Am J Physiol (1993) 1.15
Interleukin-1 receptor antagonist is upregulated during diet-induced obesity and regulates insulin sensitivity in rodents. Diabetologia (2005) 1.15
Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis. EMBO J (1996) 1.15
Glucose-induced preproinsulin gene expression is inhibited by the free fatty acid palmitate. Endocrinology (1999) 1.12
Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis. EMBO J (2000) 1.11
Effects of n-alcohols on junctional coupling and amylase secretion of pancreatic acinar cells. J Cell Physiol (1989) 1.09
Regulation of exocytosis in electrically permeabilized insulin-secreting cells. Evidence for Ca2+ dependent and independent secretion. Biosci Rep (1987) 1.09
Topography of mammalian connexins in human skin. J Invest Dermatol (1994) 1.09
Cell-to-cell communication within intact human skin. J Clin Invest (1988) 1.09
Obstacles on the way to the clinical visualisation of beta cells: looking for the Aeneas of molecular imaging to navigate between Scylla and Charybdis. Diabetologia (2012) 1.09
Isolation of pancreatic islets and primary culture of the intact microorgans or of dispersed islet cells. Methods Enzymol (1990) 1.08
Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels. Diabetologia (2007) 1.06
Blockage of cell-to-cell communication within pancreatic acini is associated with increased basal release of amylase. J Cell Biol (1986) 1.05
Coupling and connexin 43 expression in microvascular and large vessel endothelial cells. Am J Physiol (1992) 1.04
Hypertension increases connexin43 in a tissue-specific manner. Circulation (1997) 1.03
In vivo modulation of gap junctions and dye coupling between B-cells of the intact pancreatic islet. Diabetes (1983) 1.03
Adequate connexin-mediated coupling is required for proper insulin production. J Cell Biol (1995) 1.02
Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension. Kidney Int (2001) 1.02
Distinctive gap junction channel types connect WB cells, a clonal cell line derived from rat liver. Am J Physiol (1991) 1.02
Inhibition of endothelial wound repair by dominant negative connexin inhibitors. Mol Biol Cell (2001) 1.00
Beta cell coupling and connexin expression change during the functional maturation of rat pancreatic islets. Diabetologia (2010) 0.99
Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells. J Biol Chem (1996) 0.99
In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy. Diabetologia (2009) 0.98
Direct communication of homologous and heterologous endocrine islet cells in culture. J Cell Biol (1982) 0.98
Gap junction development is correlated with insulin content in the pancreatic B cell. Science (1980) 0.97
Junctional communication is induced in migrating capillary endothelial cells. J Cell Biol (1989) 0.95
Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity. Int J Obes (Lond) (2012) 0.95
Effects of vitamin A deficiency and repletion on rat insulin secretion in vivo and in vitro from isolated islets. J Clin Invest (1987) 0.94
Dispersed adult rat pancreatic islet cells in culture: A, B, and D cell function. Metabolism (1984) 0.94
Cell uncoupling and protein kinase C: correlation in a cell line but not in a differentiated tissue. Am J Physiol (1988) 0.94
Upregulation of connexin 26 between keratinocytes of psoriatic lesions. J Invest Dermatol (1998) 0.93
Gap junctional coupling modulates secretion of exocrine pancreas. Proc Natl Acad Sci U S A (1987) 0.93
Repeated glucose stimulation reveals distinct and lasting secretion patterns of individual rat pancreatic B cells. J Clin Invest (1991) 0.93
Impaired β-cell-β-cell coupling mediated by Cx36 gap junctions in prediabetic mice. Am J Physiol Endocrinol Metab (2012) 0.92
Cyclic adenosine monophosphate prevents the glucocorticoid-mediated inhibition of insulin gene expression in rodent islet cells. J Clin Invest (1992) 0.92
Association of the connexin36 gene with juvenile myoclonic epilepsy. J Med Genet (2004) 0.92
Cell coupling modulates the contraction of fibroblast-populated collagen lattices. J Cell Physiol (2000) 0.92
Monolayer cultures of adult pancreatic islet cells on osmotically disrupted fibroblasts. Diabetes (1980) 0.91
The murine orthologue of the Golgi-localized TPTE protein provides clues to the evolutionary history of the human TPTE gene family. Hum Genet (2001) 0.91
Cellular mechanisms of insulin release. Effects of retinoids on rat islet cell-to-cell adhesion, reaggregation, and insulin release. Diabetes (1983) 0.91
Actively synthesizing beta-cells secrete preferentially after glucose stimulation. Endocrinology (1991) 0.90
General and conditional replacement of connexin43-coding DNA by a lacZ reporter gene for cell-autonomous analysis of expression. Cell Commun Adhes (2001) 0.90
Differential expression of connexins during stratification of human keratinocytes. J Invest Dermatol (2000) 0.89
Glucokinase and glucokinase regulatory protein: mutual dependence for nuclear localization. Biochem J (2000) 0.89
Glucose regulates proinsulin and prosomatostatin but not proglucagon messenger ribonucleic acid levels in rat pancreatic islets. Endocrinology (2000) 0.88
Extent and modulation of junctional communication between pancreatic acinar cells in vivo. Am J Physiol (1991) 0.88
Basic fibroblast growth factor increases junctional communication and connexin 43 expression in microvascular endothelial cells. J Cell Physiol (1992) 0.88
Cortical granule release in human follicular oocytes. Biol Reprod (1977) 0.88
Aortic connexin43 is decreased during hypertension induced by inhibition of nitric oxide synthase. Arterioscler Thromb Vasc Biol (1999) 0.88
Nonrandom distribution of gap junctions between pancreatic beta-cells. Am J Physiol (1980) 0.87
Connexin37 in normal and pathological development of mouse heart and great arteries. Dev Dyn (2000) 0.87
Beta-cell crosstalk: a further dimension in the stimulus-secretion coupling of glucose-induced insulin release. Diabetes Metab (2002) 0.87
The distribution of murine 115-kDa epithelial microtubule-associated protein (E-MAP-115) during embryogenesis and in adult organs suggests a role in epithelial polarization and differentiation. Differentiation (1998) 0.87
The gap junction: a channel for multiple functions? Eur J Clin Invest (1988) 0.87
Metabolic coupling between cultured pancreatic b-cells. Exp Cell Res (1981) 0.87
Heterogeneous secretion of individual B cells in response to D-glucose and to nonglucidic nutrient secretagogues. Am J Physiol (1995) 0.87
Hypertension differentially affects the expression of the gap junction protein connexin43 in cardiac myocytes and aortic smooth muscle cells. Adv Exp Med Biol (1997) 0.87
The caudal-related homeodomain protein Cdx-2/3 regulates glucagon gene expression in islet cells. J Biol Chem (1996) 0.86
Enhanced secretion of amylase from exocrine pancreas of connexin32-deficient mice. J Cell Biol (1998) 0.84
Regulation of pancreatic exocrine function: a role for cell-to-cell communication? Pancreas (1987) 0.84
Ion channels of glucose-responsive and -unresponsive beta-cells. Diabetes (1991) 0.84
Insulin gene transcription is decreased rapidly by lowering glucose concentrations in rat islet cells. Diabetes (1994) 0.84
Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity. Cell Death Differ (2013) 0.83
Chronic hypertension alters the expression of Cx43 in cardiovascular muscle cells. Braz J Med Biol Res (2000) 0.82
In vivo modulation of connexins 43 and 26 of human epidermis by topical retinoic acid treatment. J Histochem Cytochem (1997) 0.82
Short and reversible uncoupling evokes little change in the gap junctions of pancreatic acinar cells. J Ultrastruct Res (1983) 0.81
Insulin, but not glucose lowering corrects the hyperglucagonemia and increased proglucagon messenger ribonucleic acid levels observed in insulinopenic diabetes. Endocrinology (1998) 0.80
Retinoic acid receptor, cytosolic retinol-binding and retinoic acid-binding protein mRNA transcripts and proteins in rat insulin-secreting cells. Diabetes (1993) 0.80
Heterogeneity and contact-dependent regulation of amylase release by individual acinar cells. J Cell Physiol (1994) 0.79
Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin. Dev Genet (1999) 0.79
Beta cell adaptation in pregnancy: a major difference between humans and rodents? Diabetologia (2010) 0.79
Molecular basis for the regulation of islet beta cell mass in mice: the role of E-cadherin. Diabetologia (2013) 0.79
Modulation of pancreatic acinar cell to cell coupling during ACh-evoked changes in cytosolic Ca2+. J Biol Chem (1999) 0.78
Rapid in vitro formation of smooth endoplasmic reticulum aggregates within peptide-producing islet cells. J Cell Physiol (1987) 0.78
Establishment and culture of insulin-secreting beta cell lines. Methods Enzymol (1990) 0.78
[Heterocellular coupling in cultures of endocrine pancreatic cells]. C R Seances Acad Sci III (1981) 0.78
Co-culture of nerve cells and pancreatic islets. Brain Res (1981) 0.78
Effects of vitamin A deficiency and repletion on rat glucagon secretion. Pancreas (1994) 0.78
Gap junctions and B-cell function. Horm Metab Res Suppl (1980) 0.77
Cx36 and the function of endocrine pancreas. Cell Commun Adhes (2001) 0.77