PubRank

W D Schleuning

Author PubWeight™ 72.29‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Characterization of the cellular binding site for the urokinase-type plasminogen activator. J Biol Chem 1989 1.93
2 Isolation and characterization of urokinase from human plasma. J Biol Chem 1982 1.47
3 The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants. J Biol Chem 1990 1.43
4 Structure of the thrombin complex with triabin, a lipocalin-like exosite-binding inhibitor derived from a triatomine bug. Proc Natl Acad Sci U S A 1997 1.38
5 Facultative polypeptide translocation allows a single mRNA to encode the secreted and cytosolic forms of plasminogen activators inhibitor 2. EMBO J 1989 1.38
6 Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension. J Clin Invest 1997 1.37
7 Purification and characterization of a plasminogen activator inhibitor from the histiocytic lymphoma cell line U-937. J Biol Chem 1986 1.33
8 Phorbol ester induces the biosynthesis of glycosylated and nonglycosylated plasminogen activator inhibitor 2 in high excess over urokinase-type plasminogen activator in human U-937 lymphoma cells. J Cell Biol 1987 1.32
9 The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3. Eur J Biochem 1996 1.16
10 Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion. J Cell Biol 1989 1.14
11 A DNA motif related to the cAMP-responsive element and an exon-located activator protein-2 binding site in the human tissue-type plasminogen activator gene promoter cooperate in basal expression and convey activation by phorbol ester and cAMP. J Biol Chem 1990 1.14
12 Triabin, a highly potent exosite inhibitor of thrombin. J Biol Chem 1995 1.14
13 Primary structure and properties of helothermine, a peptide toxin that blocks ryanodine receptors. Biophys J 1995 1.12
14 Plasminogen activators, plasminogen activator inhibitors and procoagulant analyzed in twenty human tumor cell lines. Int J Cancer 1986 1.10
15 Downstream targets of urokinase-type plasminogen-activator-mediated signal transduction. Eur J Biochem 1998 1.08
16 Isolation and characterization of the human tissue-type plasminogen activator structural gene including its 5' flanking region. J Biol Chem 1985 1.07
17 Interaction of urokinase-type plasminogenactivator (u-PA) with its cellular receptor (u-PAR) induces phosphorylation on tyrosine of a 38 kDa protein. FEBS Lett 1993 1.06
18 New androgen response elements in the murine pem promoter mediate selective transactivation. Mol Endocrinol 2001 1.04
19 An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis. J Biol Chem 1994 1.03
20 Glucocorticoid-modulated gene expression of tissue- and urinary-type plasminogen activator and plasminogen activator inhibitor 1 and 2. J Cell Biol 1988 1.03
21 Plasminogen activator inhibitor 1 and 2 are tumor necrosis factor/cachectin-responsive genes. J Exp Med 1988 1.00
22 Allelic dimorphism in the human tissue-type plasminogen activator (TPA) gene as a result of an Alu insertion/deletion event. Hum Genet 1992 0.99
23 Splice variants of the human EP3 receptor for prostaglandin E2. Eur J Biochem 1995 0.98
24 Transcripts for cysteine-rich secretory protein-1 (CRISP-1; DE/AEG) and the novel related CRISP-3 are expressed under androgen control in the mouse salivary gland. Endocrinology 1993 0.97
25 Complex-formation and inhibition of urokinase by blood plasma proteins. Biochem J 1983 0.95
26 CRISP-3, a protein with homology to plant defense proteins, is expressed in mouse B cells under the control of Oct2. Mol Cell Biol 1996 0.93
27 Androgen receptor signalling: comparative analysis of androgen response elements and implication of heat-shock protein 90 and 14-3-3eta. Mol Cell Endocrinol 2001 0.91
28 Mouse androgen-dependent epididymal glycoprotein CRISP-1 (DE/AEG): isolation, biochemical characterization, and expression in recombinant form. Mol Reprod Dev 1995 0.91
29 A general route to fingerprint analyses of peptide-antibody interactions using a clustered amino acid peptide library: comparison with a phage display library. Mol Immunol 1995 0.90
30 Chemical probes that differentially modulate peroxisome proliferator-activated receptor alpha and BLTR, nuclear and cell surface receptors for leukotriene B(4). J Biol Chem 1999 0.89
31 Plasminogen activators, activation inhibitors and alpha 2-macroglobulin produced by cultured normal and malignant human cells. Int J Cancer 1984 0.89
32 Characterization of a plasminogen activator and its inhibitor in human mesangial cells. Kidney Int 1989 0.88
33 Plasminogen activators in dextran sulfate-activated euglobulin fractions: a molecular analysis of factor XII- and prekallikrein-dependent fibrinolysis. Blood 1989 0.88
34 Bovine urokinase-type plasminogen activator and its receptor: cloning and induction by retinoic acid. Gene 1993 0.88
35 The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression. Gene 1991 0.85
36 Expression of high levels of human tissue plasminogen activator in yeast under the control of an inducible GAL promoter. Appl Microbiol Biotechnol 1992 0.85
37 Control elements between -9.5 and -3.0 kb in the human tissue-type plasminogen activator gene promoter direct spatial and inducible expression to the murine brain. Eur J Neurosci 2001 0.85
38 A proenzyme from chicken plasma similar to human plasma prekallikrein. J Biol Chem 1983 0.84
39 Inhibition of acrosin by protein C inhibitor and localization of protein C inhibitor to spermatozoa. Am J Physiol 1994 0.84
40 Some characteristics of highly purified boar sperm acrosin. Hoppe Seylers Z Physiol Chem 1974 0.84
41 Human plasma prekallikrein. Immunoaffinity purification and activation to alpha- and beta-kallikrein. J Biol Chem 1986 0.84
42 Differential androgen regulation of the murine genes for cysteine-rich secretory proteins (CRISP). Eur J Biochem 1997 0.82
43 Expression of transcripts for cysteine-rich secretory proteins (CRISPs) in the murine lacrimal gland. J Cell Physiol 1999 0.82
44 Thrombin increases proliferation and decreases fibrinolytic activity of kidney glomerular epithelial cells. J Cell Physiol 1991 0.82
45 Induction of c-fos gene expression by urokinase-type plasminogen activator in human ovarian cancer cells. FEBS Lett 1994 0.82
46 cDNA cloning of two closely related forms of human germ cell nuclear factor (GCNF). Biochim Biophys Acta 1997 0.81
47 Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-1 (CRISP-1) gene. Biochem J 1997 0.81
48 Human tissue-type plasminogen activator. Production in continuous serum-free cell culture and rapid purification. Biochem J 1985 0.81
49 Structural features mediating fibrin selectivity of vampire bat plasminogen activators. J Biol Chem 1995 0.81
50 Molecular cloning of human endothelin (ET) receptors ETA and ETB. J Cardiovasc Pharmacol 1992 0.80
51 Purification of human big endothelin 1 derived through cleavage with collagenase and dipeptidylpeptidase IV from a fusion protein expressed in Escherichia coli. Protein Expr Purif 1994 0.80
52 Mutational analysis of human endothelin receptors ETA and ETB identification of regions involved in the selectivity for endothelin 3 or cyclo-(D-Trp-D-Asp-Pro-D-Val-Leu). Eur J Biochem 1994 0.80
53 Multiple forms of boar acrosin and their relationship to proenzyme activation. Hoppe Seylers Z Physiol Chem 1976 0.80
54 Induction of fibrinolytic activity in HeLa cells by phorbol myristate acetate. Tissue-type plasminogen activator antigen and mRNA augmentation require intermediate protein biosynthesis. J Biol Chem 1985 0.80
55 Isolation and characterization of the androgen-dependent mouse cysteine-rich secretory protein-3 (CRISP-3) gene. Biochem J 1995 0.80
56 Thrombolytic properties of Desmodus rotundus (vampire bat) salivary plasminogen activator in experimental pulmonary embolism in rats. Blood 1992 0.79
57 Stable expression of human endothelin receptors ETA and ETB by transfected baby hamster kidney cells. Biochem Biophys Res Commun 1993 0.79
58 Monoclonal antibodies directed against human tissue-type plasminogen activator: a characterization of their species specificity, affinity and heavy-chain binding. Thromb Res 1987 0.79
59 Catalytic domain structure of vampire bat plasminogen activator: a molecular paradigm for proteolysis without activation cleavage. Biochemistry 1997 0.79
60 Sperm acrosin. Methods Enzymol 1976 0.79
61 Expression of active recombinant pallidipin, a novel platelet aggregation inhibitor, in the periplasm of Escherichia coli. Biochem J 1995 0.78
62 Vessel-specific gene expression in the lung: tissue plasminogen activator expression is limited to bronchial arteries and pulmonary vessels of discrete size. Chest 1998 0.78
63 Highly purified acrosomal proteinase (boar acrosin): isolation by affinity chromatography using benzamidine-cellulose and stabilization. Hoppe Seylers Z Physiol Chem 1973 0.78
64 Urokinase-type plasminogen activator biosynthesis is induced by the EJ-Ha-ras oncogene in CL26 mouse colon carcinoma cells. Int J Cancer 1989 0.78
65 Multiple forms of human acrosin: isolation and properties. Hoppe Seylers Z Physiol Chem 1976 0.78
66 Proteinases and proteinase inhibitors in the fertilization process: new concepts of control? Adv Biosci 1973 0.77
67 Bibrotoxin, a novel member of the endothelin/sarafotoxin peptide family, from the venom of the burrowing asp Atractaspis bibroni. FEBS Lett 1993 0.77
68 Extracellular cysteine residues 174 and 255 are essential for active expression of human endothelin receptor ETB in Escherichia coli. J Cardiovasc Pharmacol 1993 0.77
69 Cleavage specificity of boar acrosin on polypeptide substrates, ribonuclease and insulin B-chain. Hoppe Seylers Z Physiol Chem 1975 0.77
70 Expression of human endothelin receptor ETB by Escherichia coli transformants. Biochem Biophys Res Commun 1993 0.77
71 Tumor necrosis factor alpha increases antifibrinolytic activity of cultured human mesangial cells. Kidney Int 1992 0.77
72 Plasminogen activator inhibitor-1 deposition in the extracellular matrix of cultured human mesangial cells. Am J Pathol 1992 0.77
73 Boar acrosin, II: Amino acid composition, amino terminal residue and molecular weight estimations by ultracentrifugation. Hoppe Seylers Z Physiol Chem 1975 0.77
74 Occurrence of multiple forms of bull and ram acrosin during proenzyme activation and inhibition of activation by p-nitrophenyl p'-guanidinobenzoate. Hoppe Seylers Z Physiol Chem 1976 0.76
75 Coronary thrombolysis with Desmodus salivary plasminogen activator in dogs. Fast and persistent recanalization by intravenous bolus administration. Circulation 1994 0.76
76 Production of vampire bat plasminogen activator DSPA alpha 1 in CHO and insect cells. J Biotechnol 1995 0.76
77 Detection of a TaqI polymorphism within the human TPA gene (PLAT). Nucleic Acids Res 1991 0.75
78 XmnI polymorphism in the human TPA gene. Nucleic Acids Res 1990 0.75
79 Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard). J Exp Med 1986 0.75
80 Expression, purification and characterisation of recombinant pallidipin, a novel platelet aggregation inhibitor from the haematophageous triatomine bug Triatoma pallidipennis. Blood Coagul Fibrinolysis 1996 0.75
81 [New thrombolytic and anticoagulant drugs from the saliva of blood-sucking animals]. Pharm Unserer Zeit 1995 0.75
82 Cell-specific regulation of plasminogen activator inhibitor 1 and tissue type plasminogen activator release by human kidney mesangial cells. Biochim Biophys Acta 1992 0.75
83 Binding characteristics of recombinant human endothelin receptors ETA and ETB expressed in baby hamster kidney cells. J Cardiovasc Pharmacol 1993 0.75
84 Fibrin selectivity of the isolated protease domains of tissue-type and vampire bat salivary gland plasminogen activators. Eur J Biochem 1998 0.75
85 Low-M(r) urokinase-type plasminogen activator as a reporter protein. Gene 1995 0.75
86 Regulation of human tissue-type plasminogen activator gene transcription by epidermal growth factor and 3',5'-cyclic adenosine monophosphate. Mol Endocrinol 1991 0.75
87 Boar acrosin, I: modified isolation procedure, active-site titration and evidence for the presence of sialic acid. Hoppe Seylers Z Physiol Chem 1975 0.75
88 High-level secretion of the four salivary plasminogen activators from the vampire bat Desmodus rotundus by stably transfected baby hamster kidney cells. Gene 1992 0.75
89 Activation and subsequent degradation of proacrosin is mediated by zona pellucida glycoproteins, negatively charged polysaccharides, and DNA. Mol Reprod Dev 1991 0.75
90 Rational design of hirulog-type inhibitors of thrombin. J Comput Aided Mol Des 1994 0.75