Published in Proc Natl Acad Sci U S A on June 01, 1987
Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc Natl Acad Sci U S A (1989) 2.56
Inflammatory leukocytes and cytokines in the peptide-induced disease of experimental allergic encephalomyelitis in SJL and B10.PL mice. Proc Natl Acad Sci U S A (1992) 2.16
Cloning of the major histocompatibility complex class II promoter binding protein affected in a hereditary defect in class II gene regulation. Proc Natl Acad Sci U S A (1989) 1.92
Suppression of experimental allergic encephalomyelitis by intraventricular administration of interferon-gamma in Lewis rats. Clin Exp Immunol (1990) 1.53
Selective abrogation of major histocompatibility complex class II expression on extrahematopoietic cells in mice lacking promoter IV of the class II transactivator gene. J Exp Med (2001) 1.32
Astrocytes and glioblastoma cells express novel octamer-DNA binding proteins distinct from the ubiquitous Oct-1 and B cell type Oct-2 proteins. Nucleic Acids Res (1990) 1.32
Sequence elements required for activity of a murine major histocompatibility complex class II promoter bind common and cell-type-specific nuclear factors. Mol Cell Biol (1990) 1.29
Intrathecal application of interferon gamma. Progressive appearance of MHC antigens within the rat nervous system. Am J Pathol (1990) 1.27
The neuroprotective role of inflammation in nervous system injuries. J Neurol (2004) 1.27
Tumor necrosis factor amplifies measles virus-mediated Ia induction on astrocytes. Proc Natl Acad Sci U S A (1987) 1.18
Transfer of experimental allergic encephalomyelitis to bone marrow chimeras. Endothelial cells are not a restricting element. J Exp Med (1987) 1.15
CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis. J Exp Med (2004) 1.14
Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants. Proc Natl Acad Sci U S A (1997) 1.13
Stereospecific alignment of the X and Y elements is required for major histocompatibility complex class II DRA promoter function. Mol Cell Biol (1991) 1.12
Differential tumor necrosis factor alpha expression by astrocytes from experimental allergic encephalomyelitis-susceptible and -resistant rat strains. J Exp Med (1991) 1.10
Antigen presentation in brain: brain endothelial cells are poor stimulators of T-cell proliferation. Immunology (1989) 1.00
Resident macrophages (ramified microglia) of the adult brown Norway rat central nervous system are constitutively major histocompatibility complex class II positive. J Exp Med (1993) 0.95
Immune regulation by brain cells in the central nervous system: microglia but not astrocytes present myelin basic protein to encephalitogenic T cells under in vivo-mimicking conditions. Immunology (1992) 0.95
Expression of major histocompatibility complex antigens on mouse brain microvascular endothelial cells in relation to susceptibility to cerebral malaria. Immunology (1997) 0.93
In situ Ia expression on brain cells in the rat: autoimmune encephalomyelitis-resistant strain (BN) and susceptible strain (Lewis) compared. Immunology (1989) 0.91
Strain-Related Differences in the Immune Response: Relevance to Human Stroke. Transl Stroke Res (2016) 0.89
Susceptibility to Theiler's virus-induced demyelinating disease correlates with astrocyte class II induction and antigen presentation. Immunology (1992) 0.84
Thyroiditis after treatment with interleukin-2 and interferon alpha-2a. Br J Cancer (1990) 0.84
Heat shock protein 70 (HSP70) and complement C4 genotypes in patients with hyperthyroid Graves' disease. Clin Exp Immunol (1991) 0.83
The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis. J Neuroinflammation (2013) 0.82
Strain-specific variation in constitutive and inducible expression of MHC class II, class I and ICAM-1 on rat cerebral endothelium. Immunology (1994) 0.82
Autoimmune T cell repertoire in optic neuritis and multiple sclerosis: T cells recognising multiple myelin proteins are accumulated in cerebrospinal fluid. J Neurol Neurosurg Psychiatry (1994) 0.81
Glial grafting for demyelinating disease. Philos Trans R Soc Lond B Biol Sci (2005) 0.81
Specific suppression of major histocompatibility complex class I and class II genes in astrocytes by brain-enriched gangliosides. J Exp Med (1993) 0.81
Hyperexpression of interferon-gamma-induced MHC class II genes associated with reorganization of the cytoskeleton. Am J Pathol (1991) 0.79
Differential regulation of expression of the MHC class II molecules RT1.B and RT1.D on rat B lymphocytes: effects of interleukin-4, interleukin-13 and interferon-gamma. Immunology (1998) 0.76
Major histocompatibility complex molecules on parenchymal cells of the target organ protect against autoimmune disease. Chem Immunol Allergy (2007) 0.76
Cytokines and autoimmunity. Clin Exp Immunol (1994) 0.76
Tumor necrosis factor alpha response elements in the HLA-DRA promoter: identification of a tumor necrosis factor alpha-induced DNA-protein complex in astrocytes. Proc Natl Acad Sci U S A (1992) 0.76
Cellular infiltration in induced rat thyroiditis: phenotypic analysis and relationship to genetic restriction. Clin Exp Immunol (1989) 0.75
Binding of immunogenic peptides to Ia histocompatibility molecules. Nature (1985) 8.39
Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet (1983) 5.64
Identification of Ia glycoproteins in rat thymus and purification from rat spleen. Eur J Immunol (1979) 5.55
The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis. Eur J Immunol (1981) 3.96
Prostaglandins modulate macrophage Ia expression. Nature (1982) 3.83
Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature (1984) 3.71
Inducible expression of H-2 and Ia antigens on brain cells. Nature (1984) 3.48
Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. J Immunol (1982) 3.24
Cell type-specific enhancer element associated with a mouse MHC gene, E beta. Nature (1984) 3.16
Graft-versus-host disease induces expression of Ia antigen in rat epidermal cells and gut epithelium. Nature (1981) 3.16
Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lyt 1+ 2- T lymphocytes. J Immunol (1981) 3.15
A trans-acting class II regulatory gene unlinked to the MHC controls expression of HLA class II genes. Nature (1985) 2.16
Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. J Immunol (1985) 1.88
Genetic control of susceptibility to experimental allergic encephalomyelitis in rats. Science (1973) 1.60
Identification and quantitation of T lymphocyte subsets found in the spinal cord of the Lewis rat during acute experimental allergic encephalomyelitis. J Immunol (1983) 1.58
On the presence of Ia-positive endothelial cells and astrocytes in multiple sclerosis lesions and its relevance to antigen presentation. J Neuroimmunol (1985) 1.56
Expression of Ia antigens by cultured astrocytes treated with gamma-interferon. Neurosci Lett (1983) 1.48
Inhibition of experimental allergic encephalomyelitis in rats severely depleted of T cells. Science (1974) 1.40
Rat neural antigen-2 (RAN-2): a cell surface antigen on astrocytes, ependymal cells, Müller cells and lepto-meninges defined by a monoclonal antibody. Brain Res (1981) 1.38
Cell junctions and intramembrane particles of astrocytes and oligodendrocytes: a freeze-fracture study. Neuroscience (1982) 1.37
Anti I-A antibody suppresses active encephalomyelitis: treatment model for diseases linked to IR genes. J Exp Med (1983) 1.37
Ia expression in chronic relapsing experimental allergic encephalomyelitis induced by long-term cultured T cell lines in mice. Lab Invest (1986) 1.35
Cross-blocking studies with monoclonal antibodies against I-A molecules of haplotypes b, d and k. Eur J Immunol (1982) 1.35
Ia-restricted encephalitogenic T lymphocytes mediating EAE lyse autoantigen-presenting astrocytes. Nature (1986) 1.33
Characterization of T cell lines and clones from SJL/J and (BALB/c x SJL/J)F1 mice specific for myelin basic protein. J Immunol (1985) 1.31
Experimental allergic encephalomyelitis in inbred and outbred mice. J Immunol (1973) 1.25
Astrocytes of the brain synthesize interleukin 3-like factors. J Immunol (1985) 1.15
Allergic encephalomyelitis in the reputedly resistant Brown Norway strain of rats. J Immunol (1975) 1.09
Host genetic regulation of acute MHV-4 viral encephalomyelitis and acute experimental autoimmune encephalomyelitis in (BALB/cKe x SJL/J) recombinant-inbred mice. J Neuroimmunol (1985) 1.02
Association between susceptibility to experimental allergic encephalomyelitis and the major histocompatibility system in congenic rat strains. Clin Exp Immunol (1978) 0.91
Experimental allergic encephalomyelitis (EAE) in mice: primary control of EAE susceptibility is outside the H-2 complex. J Immunol (1982) 0.89
Effects of natural or synthetic microbial adjuvants on induction of autoimmune thyroiditis. Infect Immun (1985) 0.87
Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science (1996) 6.02
Formation and inactivation of endogenous cannabinoid anandamide in central neurons. Nature (1994) 5.70
Biased hypermutation and other genetic changes in defective measles viruses in human brain infections. Cell (1988) 4.90
Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc Natl Acad Sci U S A (1991) 4.07
Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity. J Exp Med (1998) 3.72
Astrocytes present myelin basic protein to encephalitogenic T-cell lines. Nature (1984) 3.71
Prevention of islet allograft rejection with engineered myoblasts expressing FasL in mice. Science (1996) 3.35
Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells. J Immunol (1982) 3.24
The biology and pathogenesis of coronaviruses. Curr Top Microbiol Immunol (1982) 3.12
Genomic RNA of the murine coronavirus JHM. J Gen Virol (1978) 2.78
Altered transcription of a defective measles virus genome derived from a diseased human brain. EMBO J (1987) 2.67
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. Eur J Immunol (1998) 2.44
Antigen presentation and tumor cytotoxicity by interferon-gamma-treated microglial cells. Eur J Immunol (1987) 2.41
Coronavirus JHM: cell-free synthesis of structural protein p60. J Virol (1980) 2.37
Production and detection of cold antihydrogen atoms. Nature (2002) 2.31
Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol Int (1982) 2.24
The transcriptional transactivator of human foamy virus maps to the bel 1 genomic region. Proc Natl Acad Sci U S A (1991) 2.23
Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family. EMBO J (1987) 2.23
On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases. Eur J Immunol (1989) 2.20
Low pH activates the vacuolating toxin of Helicobacter pylori, which becomes acid and pepsin resistant. J Biol Chem (1995) 2.17
The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis. Nat Med (1995) 2.08
Coronavirus JHM: intracellular protein synthesis. J Gen Virol (1981) 2.05
Tumor necrosis factor alpha in cerebrospinal fluid during bacterial, but not viral, meningitis. Evaluation in murine model infections and in patients. J Exp Med (1988) 2.02
Sequence divergence of measles virus haemagglutinin during natural evolution and adaptation to cell culture. J Gen Virol (1997) 2.00
Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L). Proc Natl Acad Sci U S A (1999) 1.99
A model of homelessness among male veterans of the Vietnam War generation. Am J Psychiatry (1994) 1.97
Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes (2001) 1.95
CD150 (SLAM) is a receptor for measles virus but is not involved in viral contact-mediated proliferation inhibition. J Virol (2001) 1.94
Old galaxies in the young Universe. Nature (2004) 1.90
Receptor usage and differential downregulation of CD46 by measles virus wild-type and vaccine strains. Proc Natl Acad Sci U S A (1995) 1.89
Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro. Proc Natl Acad Sci U S A (1996) 1.89
Astrocytes as antigen-presenting cells. I. Induction of Ia antigen expression on astrocytes by T cells via immune interferon and its effect on antigen presentation. J Immunol (1985) 1.88
Induction of maturation of human blood dendritic cell precursors by measles virus is associated with immunosuppression. Proc Natl Acad Sci U S A (1997) 1.85
Expression of defective measles virus genes in brain tissues of patients with subacute sclerosing panencephalitis. J Virol (1986) 1.84
Mutated and hypermutated genes of persistent measles viruses which caused lethal human brain diseases. Virology (1989) 1.82
Correlation between sites of limited proteolysis and segmental mobility in thermolysin. Biochemistry (1986) 1.80
Immunosuppression and transforming growth factor-beta in glioblastoma. Preferential production of transforming growth factor-beta 2. J Immunol (1989) 1.79
Successful vaccine-induced seroconversion by single-dose immunization in the presence of measles virus-specific maternal antibodies. J Virol (2000) 1.74
Synthesis of interleukin 1/endogenous pyrogen in the brain of endotoxin-treated mice: a step in fever induction? J Immunol (1984) 1.71
Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects. J Immunol (1984) 1.68
Infectious DNA of the human spumaretrovirus. Nucleic Acids Res (1990) 1.67
Outcome of intensive inpatient treatment for combat-related posttraumatic stress disorder. Am J Psychiatry (1996) 1.65
Expression of measles virus V protein is associated with pathogenicity and control of viral RNA synthesis. J Virol (1998) 1.63
Theta-frequency bursting and resonance in cerebellar granule cells: experimental evidence and modeling of a slow k+-dependent mechanism. J Neurosci (2001) 1.62
Comparison of subacute sclerosing panencephalitis and measles viruses: an electron microscope study. J Virol (1971) 1.61
Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis. J Exp Med (1997) 1.61
Temporal and geographical distribution of measles virus genotypes. J Gen Virol (1995) 1.61
Identification of the major immunogenic structural proteins of human foamy virus. J Gen Virol (1990) 1.60
Human immunodeficiency virus type 1 (HIV-1) infection of the central nervous system: an evaluation of cytokines in cerebrospinal fluid. J Neuroimmunol (1989) 1.59
T cell suppressor factor from human glioblastoma cells is a 12.5-kd protein closely related to transforming growth factor-beta. EMBO J (1987) 1.59
Differential downregulation of CD46 by measles virus strains. J Virol (1995) 1.57
Fusion of cultured multiple-sclerosis brain cells with indicator cells: presence of nucleocapsids and virions and isolation of parainfluenza-type virus. Lancet (1972) 1.55
Altered ratios of measles virus transcripts in diseased human brains. Virology (1987) 1.55
Sorafenib in patients with advanced biliary tract carcinoma: a phase II trial. Br J Cancer (2009) 1.54
Identification of a T cell chemotactic factor in the cerebrospinal fluid of HIV-1-infected individuals as interferon-gamma inducible protein 10. J Neuroimmunol (1999) 1.53
Alcohol consumption and risk of Hodgkin's lymphoma and multiple myeloma: a multicentre case-control study. Ann Oncol (2006) 1.52
Dissociation and posttraumatic stress disorder in Vietnam combat veterans. Am J Psychiatry (1992) 1.52
The failure of current immunotherapy for malignant glioma. Tumor-derived TGF-beta, T-cell apoptosis, and the immune privilege of the brain. Brain Res Brain Res Rev (1995) 1.51
Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. Cancer Res (1992) 1.51
Modification of the single tryptophan residue of staphylococcal nuclease by a new mild oxidizing agent. J Biol Chem (1970) 1.51
Specificity of IgM antibodies in acute human coxsackievirus B infections, analysed by indirect solid phase enzyme immunoassay and immunoblot technique. J Gen Virol (1983) 1.50
Membrane proteins of subacute sclerosing panencephalitis and measles viruses. Nature (1978) 1.49
Interleukin 6 production in experimental cerebral malaria: modulation by anticytokine antibodies and possible role in hypergammaglobulinemia. J Exp Med (1990) 1.48
Characterization of a variant virus selected in rat brains after infection by coronavirus mouse hepatitis virus JHM. J Virol (1985) 1.48
Physical association of moesin and CD46 as a receptor complex for measles virus. J Virol (1995) 1.48
TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune-mediated CNS disease. Brain (2000) 1.47
Differential expression of transforming growth factor-beta 1, -beta 2, and -beta 3 by glioblastoma cells, astrocytes, and microglia. J Immunol (1992) 1.47
Viral particles induce Ia antigen expression on astrocytes. Nature (1986) 1.46
Measles virus-induced immune suppression in the cotton rat (Sigmodon hispidus) model depends on viral glycoproteins. J Virol (1997) 1.45
Anti-Fas/APO-1 antibody-mediated apoptosis of cultured human glioma cells. Induction and modulation of sensitivity by cytokines. J Clin Invest (1994) 1.45
Moesin: a cell membrane protein linked with susceptibility to measles virus infection. Virology (1994) 1.44
Antigenic determinants of measles virus hemagglutinin associated with neurovirulence. J Virol (1994) 1.43
MxA-dependent inhibition of measles virus glycoprotein synthesis in a stably transfected human monocytic cell line. J Virol (1993) 1.43
Transcription inhibition and other properties of matrix proteins expressed by M genes cloned from measles viruses and diseased human brain tissue. J Virol (1994) 1.42
Clonal expansion of hypermutated measles virus in a SSPE brain. Virology (1993) 1.42
Subacute sclerosing panencephalitis: a review. Curr Top Microbiol Immunol (1972) 1.41
Sulfenyl halides as modifying reagents for polypeptides and proteins. I. Modification of tryptophan residues. Biochemistry (1968) 1.41
Maturation of dendritic cells is accompanied by rapid transcriptional silencing of class II transactivator (CIITA) expression. J Exp Med (2001) 1.40
Chemokines and chemotaxis of leukocytes in infectious meningitis. J Neuroimmunol (1998) 1.40
The structure and replication of coronaviruses. Curr Top Microbiol Immunol (1982) 1.40
Gamma interferon is a major mediator of antiviral defense in experimental measles virus-induced encephalitis. J Virol (1995) 1.40
Production of B cell stimulatory factor-2 and interferon gamma in the central nervous system during viral meningitis and encephalitis. Evaluation in a murine model infection and in patients. J Exp Med (1988) 1.40
Images in cardiovascular medicine. Idiopathic hypereosinophilic vasculitis. Circulation (1995) 1.39
Chemicals and drugs as triggers of food-associated disorder. Ann Allergy (1988) 1.39
Generation and properties of measles virus mutations typically associated with subacute sclerosing panencephalitis. Ann N Y Acad Sci (1994) 1.39
Subacute sclerosing panencephalitis is typically characterized by alterations in the fusion protein cytoplasmic domain of the persisting measles virus. Virology (1992) 1.39
The H gene of rodent brain-adapted measles virus confers neurovirulence to the Edmonston vaccine strain. J Virol (1999) 1.38
Disruption of Akt kinase activation is important for immunosuppression induced by measles virus. Nat Med (2001) 1.38
A galaxy rapidly forming stars 700 million years after the Big Bang at redshift 7.51. Nature (2013) 1.37
Cell junctions and intramembrane particles of astrocytes and oligodendrocytes: a freeze-fracture study. Neuroscience (1982) 1.37
Structural polypeptides of the murine coronavirus JHM. J Gen Virol (1979) 1.37
Requirement for endocytic antigen processing and influence of invariant chain and H-2M deficiencies in CNS autoimmunity. J Clin Invest (2001) 1.36
Adoptive transfer of EAE-like lesions from rats with coronavirus-induced demyelinating encephalomyelitis. Nature (1983) 1.36
Antibody-induced restriction of viral gene expression in measles encephalitis in rats. J Virol (1990) 1.36
Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci (1999) 1.35
Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation. J Clin Invest (1995) 1.35
Identification of several different lineages of measles virus. J Gen Virol (1991) 1.35
Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci Lett (1991) 1.35