Islet cell antibodies identify latent type I diabetes in patients aged 35-75 years at diagnosis.

PubWeight™: 1.26‹?› | Rank: Top 10%

🔗 View Article (PMID 3510930)

Published in Diabetes on February 01, 1986

Authors

L C Groop, G F Bottazzo, D Doniach

Associated clinical trials:

Preferred Treatment of Type 1.5 Diabetes | NCT00194896

Articles citing this

Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus. J Clin Invest (1992) 1.63

GAD antibody positivity predicts type 2 diabetes in an adult population. Diabetes (2009) 1.12

Longitudinal changes in epitope recognition of autoantibodies against glutamate decarboxylase 65 (GAD65Ab) in prediabetic adults developing diabetes. Clin Exp Immunol (2007) 1.02

ZnT8 is a major CD8+ T cell-recognized autoantigen in pediatric type 1 diabetes. Diabetes (2012) 0.97

Distinct clinical and laboratory characteristics of latent autoimmune diabetes in adults in relation to type 1 and type 2 diabetes mellitus. World J Diabetes (2014) 0.92

LADA: time for a new definition. Diabetes (2013) 0.89

When to use insulin in the maturity onset diabetic. Postgrad Med J (1987) 0.89

Impact of islet autoimmunity on the progressive β-cell functional decline in type 2 diabetes. Diabetes Care (2014) 0.84

Latent autoimmune diabetes of adults is phenotypically similar to type 1 diabetes in a minority population. J Clin Endocrinol Metab (2011) 0.83

Altered natural killer (NK) cell frequency and phenotype in latent autoimmune diabetes in adults (LADA) prior to insulin deficiency. Clin Exp Immunol (2010) 0.82

Epitope analysis of insulin autoantibodies using recombinant Fab. Clin Exp Immunol (2005) 0.82

Islet autoimmunity in phenotypic type 2 diabetes patients. Diabetes Obes Metab (2013) 0.81

Characteristics and Prevalence of Latent Autoimmune Diabetes in Adults (LADA). ISRN Pharmacol (2012) 0.80

Altered regulatory T cell phenotype in latent autoimmune diabetes of the adults (LADA). Clin Exp Immunol (2016) 0.80

Misunderstanding in the classification of diabetes mellitus. What's in a name? West J Med (1993) 0.80

Unusual clustering of diseases in a Canadian Old Colony (Chortitza) Mennonite kindred and community. CMAJ (1988) 0.80

Practical Classification Guidelines for Diabetes in patients treated with insulin: a cross-sectional study of the accuracy of diabetes diagnosis. Br J Gen Pract (2016) 0.78

Association of TCF7L2 variation with single islet autoantibody expression in children with type 1 diabetes. BMJ Open Diabetes Res Care (2014) 0.78

Association of major histocompatibility complex class 1 chain-related gene a dimorphism with type 1 diabetes and latent autoimmune diabetes in adults in the Algerian population. Clin Vaccine Immunol (2012) 0.78

Contribution of SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study. BMC Endocr Disord (2014) 0.76

IGF2BP2 alternative variants associated with glutamic acid decarboxylase antibodies negative diabetes in Malaysian subjects. PLoS One (2012) 0.76

Structural Properties of Gene Promoters Highlight More than Two Phenotypes of Diabetes. PLoS One (2015) 0.75

Occurrence of type 1 diabetes in graves' disease patients who are positive for antiglutamic Acid decarboxylase antibodies: an 8-year followup study. J Thyroid Res (2010) 0.75

Articles by these authors

Tissue antibodies in primary biliary cirrhosis, active chronic (lupoid) hepatitis, cryptogenic cirrhosis and other liver diseases and their clinical implications. Clin Exp Immunol (1966) 8.26

Role of aberrant HLA-DR expression and antigen presentation in induction of endocrine autoimmunity. Lancet (1983) 5.64

Islet-cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet (1974) 5.59

In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis. N Engl J Med (1985) 4.65

Aberrant expression of HLA-DR antigen on thyrocytes in Graves' disease: relevance for autoimmunity. Lancet (1983) 3.85

A unified concept of autoimmune hepatitis. Lancet (1969) 3.74

Type 1 (insulin-dependent) diabetes and a highly variable locus close to the insulin gene on chromosome 11. Diabetologia (1985) 3.65

Effect of captopril on progression to clinical proteinuria in patients with insulin-dependent diabetes mellitus and microalbuminuria. European Microalbuminuria Captopril Study Group. JAMA (1994) 3.38

Intrinsic-factor antibodies in absence of pernicious anaemia. 3-7 year follow-up. Lancet (1970) 3.36

A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26

Interferon-gamma induces HLA-DR expression by thyroid epithelium. Clin Exp Immunol (1985) 3.18

Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature (1985) 3.11

Types of 'reticulin' antibodies detected in human sera by immunofluorescence. J Clin Pathol (1973) 2.98

HLA class II induction in human islet cells by interferon-gamma plus tumour necrosis factor or lymphotoxin. Nature (1987) 2.96

Novel organ-specific circulating cardiac autoantibodies in dilated cardiomyopathy. J Am Coll Cardiol (1990) 2.67

Prediction of IDDM in the general population: strategies based on combinations of autoantibody markers. Diabetes (1997) 2.65

The selection of control subjects for case/control analysis of susceptibility to type 1 (insulin-dependent) diabetes mellitus. Diabetologia (1993) 2.63

Unexplained hepatitis following halothane. Br Med J (1976) 2.62

Microsomal antibodies in active chronic hepatitis and other disorders. Clin Exp Immunol (1973) 2.59

Genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height. Am J Hum Genet (2001) 2.50

Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families. Nat Genet (1996) 2.48

UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes. UK Prospective Diabetes Study Group. Lancet (1997) 2.47

Evidence for a long prediabetic period in type I (insulin-dependent) diabetes mellitus. Lancet (1982) 2.43

Aberrant expression of HLA-DR antigens on bileduct epithelium in primary biliary cirrhosis: relevance to pathogenesis. Lancet (1984) 2.38

Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies. Diabetes (1999) 2.36

Mitochondrial antibodies and subclinical liver disease. Q J Med (1970) 2.28

Human T-cell clones from autoimmune thyroid glands: specific recognition of autologous thyroid cells. Science (1985) 2.27

What is the benefit of increasing the sulfonylurea dose? Ann Intern Med (1993) 2.16

Antibodies to glutamic acid decarboxylase reveal latent autoimmune diabetes mellitus in adults with a non-insulin-dependent onset of disease. Diabetes (1993) 2.15

Mitochondrial antibodies in primary biliary cirrhosis. I. Localization of the antigen to mitochondrial membranes. J Exp Med (1967) 2.09

Classification of smooth muscle autoantibodies detected by immunofluorescence. J Clin Pathol (1976) 2.08

Genetic and immunologic factors in microvascular disease in type I insulin-dependent diabetes. Diabetes (1982) 2.05

Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity. Clin Exp Immunol (1981) 2.04

No risk of diabetes after insulin-shock treatment. Lancet (1992) 2.02

A collagen disorder of the nervous system presenting as multiple sclerosis. Brain (1972) 2.00

The occurrence of autoantibodies in infectious mononucleosis. Clin Exp Immunol (1974) 2.00

Complement-fixing islet-cell antibodies in type-I diabetes: possible monitors of active beta-cell damage. Lancet (1980) 2.00

New antibody in early syphilis. Lancet (1970) 1.97

Autoantibodies to a 128-kd synaptic protein in three women with the stiff-man syndrome and breast cancer. N Engl J Med (1993) 1.95

Autoantibodies to prolactin-secreting cells of human pituitary. Lancet (1975) 1.92

Histocompatibility antigens, autoantibodies, and immunoglobulins in alcoholic liver disease. Br Med J (1976) 1.91

Insulin secretion and insulin sensitivity in relation to glucose tolerance: lessons from the Botnia Study. Diabetes (2000) 1.90

Enhanced antibody responses in active chronic hepatitis: relation to HLA-B8 and HLA-B12 and porto-systemic shunting. Lancet (1976) 1.89

Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial. Gastroenterology (1985) 1.86

The Continuous Glucose Monitoring System (CGMS) in type 1 diabetic children is the way to reduce hypoglycemic risk. Diabetes Metab Res Rev (2002) 1.85

Organ-specific autoimmunity: a 1986 overview. Immunol Rev (1986) 1.84

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes (1994) 1.82

Predicting insulin-dependent diabetes. Lancet (1988) 1.75

Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med (1995) 1.70

Mitochondrial antibodies in chronic liver diseases and connective tissue disorders: further characterization of the autoantigens. Clin Exp Immunol (1980) 1.66

Hepatic disorders associated with liver-kidney microsomal antibodies. Br Med J (1974) 1.64

Evidence for an association between rheumatoid arthritis and autoimmune endocrine disease. Ann Rheum Dis (1983) 1.64

Immunological studies in an epidemic of infective, short-incubation hepatitis. Lancet (1972) 1.62

Mitochondrial antibodies (AMA). Gut (1974) 1.60

Predictive value of microalbuminuria in patients with insulin-dependent diabetes of long duration. BMJ (1992) 1.60

Assessment of beta-cell function during the oral glucose tolerance test by a minimal model of insulin secretion. Eur J Clin Invest (2001) 1.59

From the fetal liver to spleen and gut: the highway to natural antibody. Mucosal Immunol (2009) 1.59

Subclinical coeliac disease in schoolchildren from northern Sardinia. Lancet (1999) 1.58

High prevalence of seroimmunologic abnormalities in relatives of patients with active chronic hepatitis or primary biliary cirrhosis. N Engl J Med (1974) 1.56

Protracted diarrhoea of infancy: evidence in support of an autoimmune variant. Br Med J (Clin Res Ed) (1986) 1.55

Evidence for a primary autoimmune type of diabetes mellitus. Br Med J (1978) 1.55

Metabolic and genetic characterization of prediabetic states. Sequence of events leading to non-insulin-dependent diabetes mellitus. J Clin Invest (1994) 1.54

Quantification of islet-cell antibodies and prediction of insulin-dependent diabetes. Lancet (1990) 1.54

Mitochondrial and other tissue antibodies in relatives of patients with primary biliary cirrhosis. Clin Exp Immunol (1972) 1.50

Characterization of the microsomal antigen related to a subclass of active chronic hepatitis. Immunology (1974) 1.50

Is mitochondrial antibody diagnostic of primary biliary cirrhosis? Gut (1981) 1.50

Immunopathology of liver disease. Prog Liver Dis (1972) 1.47

"Autoallergic" hepatitis. N Engl J Med (1970) 1.46

Non-organ-specific cytoplasmic antibodies detected by immunofluorescence. Int Arch Allergy Appl Immunol (1971) 1.46

Autoimmunity in pernicious anemia and thyroiditis: a family study. Ann N Y Acad Sci (1965) 1.45

Mitochondrial antibodies in primary biliary cirrhosis. 3. Characterization of the inner-membrane complement fixing antigen. Clin Exp Immunol (1969) 1.45

Primary biliary cirrhosis in brothers. Postgrad Med J (1975) 1.44

A family study of the association between insulin dependent diabetes mellitus, autoantibodies and the HLA system. Tissue Antigens (1984) 1.44

Autoantibodies to cartilage and type II collagen in relapsing polychondritis and other rheumatic diseases. Ann Rheum Dis (1981) 1.42

Autoimmunity in liver diseases. Prog Clin Immunol (1972) 1.39

Identification of alpha- and beta-cardiac myosin heavy chain isoforms as major autoantigens in dilated cardiomyopathy. Circulation (1992) 1.38

The concept of an 'autoallergic' hepatitis. Proc R Soc Med (1970) 1.37

Mitochondrial and other tissue autoantibodies in patients with biological false positive reactions for syphilis. Clin Exp Immunol (1970) 1.37

Goitrous autoimmune thyroiditis (Hashimoto's disease). Clin Endocrinol Metab (1979) 1.36

Mitochondrial antibodies in primary biliary cirrhosis. IV. Significance of membrane structure for the complement-fixing antigen. Immunology (1969) 1.35

Ribosomal antibodies detected by immunofluorescence in systemic lupus erythematosus and other collagenoses. Clin Exp Immunol (1974) 1.33

Clinical pattern and course of disease in primary biliary cirrhosis based on an analysis of 236 patients. Gastroenterology (1980) 1.33

Quantitative distribution of human thyroglobulin autoantibodies in different immunoglobulin classes. Clin Exp Immunol (1968) 1.33

Immunofluorescence studies on autoantibodies to steroid-producing cells, and to germline cells in endocrine disease and infertility. Clin Exp Immunol (1980) 1.32

Type I (insulin dependent) diabetes: a disease of slow clinical onset? Br Med J (Clin Res Ed) (1987) 1.32

Genomewide search for type 2 diabetes mellitus susceptibility loci in Finnish families: the Botnia study. Am J Hum Genet (2002) 1.31

Autoantibodies to vasopressin cells in idiopathic diabetes insipidus: evidence for an autoimmune variant. Lancet (1983) 1.31

Islet autoantibody markers in IDDM: risk assessment strategies yielding high sensitivity. Diabetologia (1995) 1.31

Serum thyroglobulin levels in healthy subjects and in patients with thyroid disease. J Clin Endocrinol Metab (1969) 1.30