Published in Drug Metab Dispos on July 16, 1979
Chirality and drugs used in psychiatry: nice to know or need to know? Cell Mol Neurobiol (1999) 0.92
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am J Hum Genet (2000) 4.42
Genome-wide association study of recurrent early-onset major depressive disorder. Mol Psychiatry (2010) 2.05
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Mol Psychiatry (2009) 2.03
Sea urchin (lytechinus pictus) late-stage histone H3 and H4 genes: characterization and mapping of a clustered but nontandemly linked multigene family. Cell (1982) 1.69
TULP1 mutation in two extended Dominican kindreds with autosomal recessive retinitis pigmentosa. Nat Genet (1998) 1.60
Genome-wide association study of obsessive-compulsive disorder. Mol Psychiatry (2012) 1.57
Genome-wide association study of Tourette's syndrome. Mol Psychiatry (2012) 1.42
Apparent mtDNA heteroplasmy in Alzheimer's disease patients and in normals due to PCR amplification of nucleus-embedded mtDNA pseudogenes. Proc Natl Acad Sci U S A (1997) 1.36
BMPR2 germline mutations in pulmonary hypertension associated with fenfluramine derivatives. Eur Respir J (2002) 1.31
Refinement of the spinal muscular atrophy locus to the interval between D5S435 and MAP1B. Genomics (1993) 1.28
BMPR2 mutations in pulmonary arterial hypertension with congenital heart disease. Eur Respir J (2004) 1.28
Identification of a novel member of the TGF-beta superfamily highly expressed in human placenta. Gene (1997) 1.26
Investigation of serotonin-related genes in antidepressant response. Mol Psychiatry (2004) 1.26
Alcohol oxidase, a flavoprotein from several Basidiomycetes species. Crystallization by fractional precipitation with polyethylene glycol. Biochim Biophys Acta (1968) 1.25
Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective. Psychol Med (2011) 1.25
Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q. Mol Psychiatry (2006) 1.24
Fine mapping of PPH1, a gene for familial primary pulmonary hypertension, to a 3-cM region on chromosome 2q33. Am J Respir Crit Care Med (2000) 1.21
Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study. Am J Med Genet B Neuropsychiatr Genet (2009) 1.21
Potential panic disorder syndrome: clinical and genetic linkage evidence. Am J Med Genet (2000) 1.20
Evidence for a putative bipolar disorder locus on 2p13-16 and other potential loci on 4q31, 7q34, 8q13, 9q31, 10q21-24, 13q32, 14q21 and 17q11-12. Mol Psychiatry (2003) 1.19
Central nervous system and cardiovascular effects of lorazepam in man. Clin Pharmacol Ther (1971) 1.17
Temporal expression of late histone messenger RNA in the sea urchin Lytechinus pictus. Proc Natl Acad Sci U S A (1984) 1.17
Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics. Am J Hum Genet (2001) 1.13
Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. I. Isolation and purification. Biochim Biophys Acta (1968) 1.13
Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics. Mol Psychiatry (2004) 1.13
Comparison of the late H1 histone genes of the sea urchins Lytechinus pictus and Strongelocentrotus purpuratus. Nucleic Acids Res (1986) 1.09
Tubby-like protein 1 homozygous splice-site mutation causes early-onset severe retinal degeneration. Invest Ophthalmol Vis Sci (1999) 1.09
The human GCAP1 and GCAP2 genes are arranged in a tail-to-tail array on the short arm of chromosome 6 (p21.1). Genomics (1997) 1.08
A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet (1999) 1.07
Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder. Am J Med Genet (2000) 1.04
Primary pulmonary hypertension in families with hereditary haemorrhagic telangiectasia. Eur Respir J (2004) 1.03
A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families. Am J Med Genet B Neuropsychiatr Genet (2009) 1.03
Clinical pharmacokinetics of lorazepam. II. Intramuscular injection. Clin Pharmacol Ther (1977) 1.02
Introduction of a composite parameter to the pharmacokinetics of venlafaxine and its active O-desmethyl metabolite. J Clin Pharmacol (1992) 1.00
Perils of gene mapping with microsatellite markers. Am J Hum Genet (1992) 0.99
Obsessive-compulsive disorder: subclassification based on co-morbidity. Psychol Med (2008) 0.97
Isolation, characterization, and expression of the gene encoding the late histone subtype H1-gamma of the sea urchin Strongylocentrotus purpuratus. Mol Cell Biol (1987) 0.97
Carbohydrate oxidase, a novel enzyme from Polyporus obtusus. II. Specificity and characterization of reaction products. Biochim Biophys Acta (1968) 0.95
Clinical pharmacokinetics of lorazepam. III. Intravenous injection. Preliminary results. J Clin Pharmacol (1977) 0.94
Meta-analysis of association between obsessive-compulsive disorder and the 3' region of neuronal glutamate transporter gene SLC1A1. Am J Med Genet B Neuropsychiatr Genet (2013) 0.93
Production of alcohol oxidase by several Basidiomycetes. Appl Microbiol (1969) 0.93
Disposition of 7-chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one (lorazepam) in humans. Determination of the drug by electron capture gas chromatography. Arzneimittelforschung (1971) 0.93
Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study. Mol Psychiatry (2009) 0.92
Absorption and excretion of 7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one (oxazepam) in humans. Determination of the drug by gas-liquid chromatography with electron capture detection. Arzneimittelforschung (1972) 0.91
Breast milk: a source of more than nutrition for the neonate. Clin Toxicol (1974) 0.90
Lack of genetic linkage or association between a functional serotonin transporter polymorphism and panic disorder. Psychiatr Genet (1999) 0.89
Metabolic disposition of 14C-venlafaxine in mouse, rat, dog, rhesus monkey and man. Xenobiotica (1993) 0.89
Metabolism and kinetics of oxaprozin in normal subjects. Clin Pharmacol Ther (1980) 0.89
The application of in vitro models of drug metabolism and toxicity in drug discovery and drug development. Drug Chem Toxicol (1995) 0.88
Poricin, an acidic protein with antitumor activity from a basidiomycete. I. Production, isolation, and purification. Arch Biochem Biophys (1968) 0.88
Alcohol oxidase, a novel enzyme from a basidiomycete. Biochem Biophys Res Commun (1965) 0.88
The binding of seotonin in brain: a study in vitro of the influence of physicochemical factors and drugs. Biochem Pharmacol (1968) 0.87
Pharmacokinetics of venlafaxine and O-desmethylvenlafaxine in laboratory animals. Xenobiotica (1994) 0.87
Relationship of guanabenz concentrations in brain and plasma to antihypertensive effect in the spontaneously hypertensive rat. J Pharmacol Exp Ther (1980) 0.86
Disposition and metabolism of lorazepam in the male rat. Drug Metab Dispos (1977) 0.86
The deletion polymorphism and Val1000Ile in alpha-2-macroglobulin and Alzheimer disease in Caribbean Hispanics. Neurosci Lett (2000) 0.85
Urinary metabolites of DL-norgestrel in women. Acta Endocrinol (Copenh) (1973) 0.85
Disposition of 4,5-diphenyl-2-oxazolepropionic acid (oxaprozin) in beagle dogs and rhesus monkeys. Drug Metab Dispos (1978) 0.85
Fine genetic mapping of a gene for autosomal recessive retinitis pigmentosa on chromosome 6p21. Am J Hum Genet (1995) 0.85
Species-dependent enantioselective glucuronidation of three 2-arylpropionic acids. Naproxen, ibuprofen, and benoxaprofen. Drug Metab Dispos (1988) 0.83
Association between a catechol-o-methyltransferase polymorphism and obsessive-compulsive disorder in the Afrikaner population. J Affect Disord (2001) 0.83
Pyranose oxidase from Polyporus obtusus. Methods Enzymol (1975) 0.82
Homeobox genes in obsessive-compulsive disorder. Am J Med Genet B Neuropsychiatr Genet (2011) 0.81
Genetic aspects of pulmonary arterial hypertension. Ann Med (2001) 0.81
Clinical pharmacokinetics of lorazepam. I. Absorption and disposition of oral 14C-lorazepam. Clin Pharmacol Ther (1976) 0.81
Stereoselective biotransformations of dl-norgestrel and its enantiomers in the African green monkey. Drug Metab Dispos (1974) 0.81
Species-related differences in the stereoselective glucuronidation of oxazepam. Drug Metab Dispos (1983) 0.81
Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families. Am J Med Genet B Neuropsychiatr Genet (2009) 0.81
Pinworms--Incidence, predictability and treatment with thiabendazole. Calif Med (1967) 0.80
Parent-of-origin effect in panic disorder. Am J Med Genet (1999) 0.80
Reactions of oxaprozin-1-O-acyl glucuronide in solutions of human plasma and albumin. Adv Exp Med Biol (1986) 0.79
High-resolution mapping and transcript identification at the progressive epilepsy with mental retardation locus on chromosome 8p. Genome Res (1997) 0.79
The disposition of venlafaxine enantiomers in dogs, rats, and humans receiving venlafaxine. Chirality (1992) 0.79
Pharmacokinetic disposition of guanabenz in the rhesus monkey. Drug Metab Dispos (1982) 0.79
Interactions between oxaprozin glucuronide and human serum albumin. Xenobiotica (1987) 0.79
Protein binding and clearance of oxaprozin, a highly bound anti-inflammatory agent. Agents Actions (1982) 0.79
The presence of dl-, d- and l-norgestrel and their metabolites in the plasma of women. Contraception (1975) 0.78
Extrapolation from animals to man: predictions, pitfalls and perspectives. Xenobiotica (1987) 0.78
Metabolic formation of N- and O-glucuronides of 3-(p-chlorophenyl)thiazolo[3,2-a]benzimidazole-2-acetic acid. Rearrangement of the 1-o-acyl glucuronide. Drug Metab Dispos (1983) 0.78
The metabolic disposition of oxazepam in rats. Drug Metab Dispos (1986) 0.77
The metabolic disposition of norgestrel in female rhesus monkeys. Drug Metab Dispos (1979) 0.77
The biotransformation of oxazepam (7-chloro-1,3-dihydro-3-hydroxy-5-phenyl-2H-1,4-benzodiazepin-2-one) in man, miniature swine and rat. Arzneimittelforschung (1972) 0.77