Published in Am J Pathol on September 01, 1986
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Two types of human mast cells that have distinct neutral protease compositions. Proc Natl Acad Sci U S A (1986) 3.34
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Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis. N Engl J Med (1987) 2.59
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Immunologic release of beta-hexosaminidase and beta-glucuronidase from purified rat serosal mast cells. J Immunol (1979) 2.01
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Human mast cells stimulate vascular tube formation. Tryptase is a novel, potent angiogenic factor. J Clin Invest (1997) 1.89
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Regulation of tryptase from human lung mast cells by heparin. Stabilization of the active tetramer. J Biol Chem (1986) 1.79
Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies. J Histochem Cytochem (1989) 1.79
Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells. J Immunol (1981) 1.76
Primary ovarian pregnancy successfully treated with methotrexate. Am J Obstet Gynecol (1992) 1.76
A novel heparin-dependent processing pathway for human tryptase. Autocatalysis followed by activation with dipeptidyl peptidase I. J Clin Invest (1996) 1.73
Structure and function of the chemical mediators of mast cells. Prog Allergy (1984) 1.71
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Increased serum baseline tryptase levels and extensive skin involvement are predictors for the severity of mast cell activation episodes in children with mastocytosis. Allergy (2012) 1.66
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Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J Allergy Clin Immunol (1991) 1.60
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Activation of pulmonary mast cells by bronchoalveolar allergen challenge. In vivo release of histamine and tryptase in atopic subjects with and without asthma. Am Rev Respir Dis (1988) 1.52
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Generation of C3a anaphylatoxin from human C3 by human mast cell tryptase. J Immunol (1983) 1.44
Synovial procollagenase activation by human mast cell tryptase dependence upon matrix metalloproteinase 3 activation. J Clin Invest (1989) 1.42
Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis. J Immunol (1997) 1.41
Evaluation of human peripheral blood leukocytes for mast cell tryptase. J Immunol (1987) 1.37
Cloning and characterization of a second complementary DNA for human tryptase. J Clin Invest (1990) 1.36
Vancomycin and the red-man syndrome: pharmacodynamics of histamine release. J Infect Dis (1988) 1.35
Deficiency of the tryptase-positive, chymase-negative mast cell type in gastrointestinal mucosa of patients with defective T lymphocyte function. J Immunol (1987) 1.34
Purification and subunit structure of deoxyribonucleic acid-dependent ribonucleic acid polymerase II from the mouse plasmacytoma, MOPC 315. J Biol Chem (1975) 1.33
Increased numbers of both airway basophils and mast cells in sputum after allergen inhalation challenge of atopic asthmatics. Am J Respir Crit Care Med (2000) 1.32
Development of human mast cells from umbilical cord blood cells by recombinant human and murine c-kit ligand. Proc Natl Acad Sci U S A (1993) 1.30
Monoclonal antibodies against human mast cell tryptase demonstrate shared antigenic sites on subunits of tryptase and selective localization of the enzyme to mast cells. J Immunol (1985) 1.29
Histamine and tryptase levels in patients with acute allergic reactions: An emergency department-based study. J Allergy Clin Immunol (2000) 1.29
The fibrinogenolytic activity of purified tryptase from human lung mast cells. J Immunol (1985) 1.28
Recombinant human stem cell factor stimulates differentiation of mast cells from dispersed human fetal liver cells. Blood (1992) 1.28
Recombinant human stem cell factor (kit ligand) promotes human mast cell and melanocyte hyperplasia and functional activation in vivo. J Exp Med (1996) 1.27
Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide. J Biol Chem (1997) 1.20
Markers of mast cell degranulation. Methods (1997) 1.19
Regulation of human mast cell tryptase. Effects of enzyme concentration, ionic strength and the structure and negative charge density of polysaccharides. Biochem J (1987) 1.19
Cell association of complexes of chymase, heparin proteoglycan, and protein after degranulation by rat mast cells. J Immunol (1981) 1.19
Identification of a cathepsin G-like proteinase in the MCTC type of human mast cell. J Immunol (1990) 1.19
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Encephalomyocarditis virus infection of mouse plasmacytoma cells. II. Effect on host RNA synthesis and RNA polymerases. J Virol (1974) 1.17
Immediate and late airway response of allergic rhinitis patients to segmental antigen challenge. Characterization of eosinophil and mast cell mediators. Am Rev Respir Dis (1991) 1.17
Immunohistology of the nasal mucosa following allergen-induced rhinitis. Identification of activated T lymphocytes, eosinophils, and neutrophils. Am Rev Respir Dis (1992) 1.17
Human skin-derived mast cells can proliferate while retaining their characteristic functional and protease phenotypes. Blood (2001) 1.16
Inactivation of human high molecular weight kininogen by human mast cell tryptase. J Immunol (1983) 1.15
Difficulty in removal of accidentally cut endotracheal tube. J Oral Maxillofac Surg (1982) 1.14
Development of human mast cells in vitro. Proc Natl Acad Sci U S A (1989) 1.13
Human mast cell carboxypeptidase. Selective localization to MCTC cells. J Immunol (1991) 1.12
Angiotensin I conversion by human and rat chymotryptic proteinases. J Invest Dermatol (1984) 1.12
The immediate and late allergic response to segmental bronchopulmonary provocation in asthma. Am J Respir Crit Care Med (1997) 1.11
Mast cell numbers and histamine levels in synovial fluids from patients with diverse arthritides. Arthritis Rheum (1986) 1.10
Activation of rat serosal mast cells by chymase, an endogenous secretory granule protease. J Immunol (1984) 1.10
Ultrastructural analysis of human T and TC mast cells identified by immunoelectron microscopy. Lab Invest (1988) 1.10
Enzymes of the mast cell granule. J Invest Dermatol (1980) 1.10
Synovial fluid levels of complement SC5b-9 and fragment Bb are elevated in patients with rheumatoid arthritis. Arthritis Rheum (1991) 1.09
Experimental rhinovirus 16 infection potentiates histamine release after antigen bronchoprovocation in allergic subjects. Am Rev Respir Dis (1991) 1.08
Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis. J Allergy Clin Immunol (1990) 1.07
Immunoassay of tryptase from human mast cells. J Immunol Methods (1986) 1.07
Tryptase levels in nasal-lavage fluid as an indicator of the immediate allergic response. J Allergy Clin Immunol (1988) 1.05
Ultrastructural analysis of maturing human T and TC mast cells in situ. Lab Invest (1989) 1.05
Heparin-induced recurrent anaphylaxis. Clin Exp Allergy (2004) 1.05
Airway levels of mast cell-derived mediators in exercise-induced asthma. Am Rev Respir Dis (1990) 1.04
The effects of extremely low shear stress on cellular proliferation and neointimal thickening in the failing bypass graft. J Vasc Surg (2001) 1.04
Identification and partial characterization of a unique marker for human basophils. J Immunol (1995) 1.04
Laboratory investigation of deaths due to anaphylaxis. J Forensic Sci (1991) 1.04
Quantitation of tryptase, chymase, Fc epsilon RI alpha, and Fc epsilon RI gamma mRNAs in human mast cells and basophils by competitive reverse transcription-polymerase chain reaction. J Immunol (1995) 1.03
Basophil recruitment and IL-4 production during human allergen-induced late asthma. J Allergy Clin Immunol (2001) 1.03
Chromosomal analysis of early fetal losses in relation to transvaginal ultrasonographic detection of fetal heart motion after infertility. Fertil Steril (1998) 1.03
IL-3-dependent growth of basophil-like cells and mastlike cells from human bone marrow. J Immunol (1989) 1.02
Detection and partial characterization of a human mast cell carboxypeptidase. J Immunol (1987) 0.99
Mast cell activation in arthritis: detection of alpha- and beta-tryptase, histamine and eosinophil cationic protein in synovial fluid. Clin Sci (Lond) (1997) 0.98
Immunohistology of the nasal mucosa in seasonal allergic rhinitis: increases in activated eosinophils and epithelial mast cells. J Allergy Clin Immunol (1992) 0.98
Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia. Blood (2001) 0.98
Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells. J Immunol (1997) 0.98
Activation of latent rheumatoid synovial collagenase by human mast cell tryptase. J Immunol (1988) 0.96
Abdominal aortic aneurysm with aorta-left renal vein fistula with left varicocele. J Vasc Surg (2000) 0.96
Mast cell number and phenotype in chronic idiopathic urticaria. J Allergy Clin Immunol (1995) 0.96
Mast cell heterogeneity. Clin Exp Allergy (1989) 0.95
Tear and conjunctival changes during the allergen-induced early- and late-phase responses. J Allergy Clin Immunol (2000) 0.95
Tryptase and chymase, markers of distinct types of human mast cells. Immunol Res (1989) 0.93
Mast cell changes in scleroderma. Presence of MCT cells in the skin and evidence of mast cell activation. Arthritis Rheum (1992) 0.93
Vascular complications of cardiac catheterization. J Vasc Surg (1991) 0.93
Immunohistochemical detection of human basophils in late-phase skin reactions. J Allergy Clin Immunol (1998) 0.92