Published in Mol Cell Biol on January 01, 1986
Lambda YES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations. Proc Natl Acad Sci U S A (1991) 6.82
Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis. Mol Cell Biol (1987) 5.93
Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.25
Yeast chromosome replication and segregation. Microbiol Rev (1988) 3.40
Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae. Mol Cell Biol (1988) 3.17
Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.65
Alterations in the adenine-plus-thymine-rich region of CEN3 affect centromere function in Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.57
Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation. EMBO J (1993) 2.46
Mutational analysis of the consensus sequence of a replication origin from yeast chromosome III. Mol Cell Biol (1990) 2.44
Distinct cis-acting signals enhance 3' endpoint formation of CYC1 mRNA in the yeast Saccharomyces cerevisiae. EMBO J (1991) 2.30
A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae. Mol Cell Biol (1989) 2.14
Replication forks pause at yeast centromeres. Mol Cell Biol (1992) 2.07
Nucleotide sequence heterogeneity of alpha satellite repetitive DNA: a survey of alphoid sequences from different human chromosomes. Nucleic Acids Res (1987) 1.87
Purification of a yeast centromere-binding protein that is able to distinguish single base-pair mutations in its recognition site. Mol Cell Biol (1989) 1.82
Purification of a protein binding to the CDEI subregion of Saccharomyces cerevisiae centromere DNA. Mol Cell Biol (1989) 1.52
Isolation and characterization of a Saccharomyces cerevisiae peptide transport gene. Mol Cell Biol (1994) 1.49
Mutations in CEN3 cause aberrant chromosome segregation during meiosis in Saccharomyces cerevisiae. Genetics (1989) 1.40
Mutations in a conserved region of RNA polymerase II influence the accuracy of mRNA start site selection. Mol Cell Biol (1991) 1.39
Physiological levels of normal tRNA(CAGGln) can effect partial suppression of amber mutations in the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1987) 1.05
Unstable amplification of two extrachromosomal elements in alpha-difluoromethylornithine-resistant Leishmania donovani. Mol Cell Biol (1992) 1.05
Size threshold for Saccharomyces cerevisiae chromosomes: generation of telocentric chromosomes from an unstable minichromosome. Mol Cell Biol (1986) 0.97
Centromeric regions control autonomous segregation tendencies in single-division meiosis of Saccharomyces cerevisiae. Genetics (1990) 0.96
Functional selection for the centromere DNA from yeast chromosome VIII. Nucleic Acids Res (1995) 0.94
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 20.61
Centromeric DNA from Saccharomyces cerevisiae. J Mol Biol (1982) 9.64
Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss. Cell (1985) 8.78
Functional selection and analysis of yeast centromeric DNA. Cell (1985) 7.74
Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs. Cell (1982) 7.01
Centromeric DNA from chromosome VI in Saccharomyces cerevisiae strains. EMBO J (1982) 5.71
Pedigree analysis of plasmid segregation in yeast. Cell (1983) 4.65
A physical, genetic and transcriptional map of the cloned his3 gene region of Saccharomyces cerevisiae. J Mol Biol (1980) 3.35
Genomic substitutions of centromeres in Saccharomyces cerevisiae. Nature (1983) 2.76
Direct selection procedure for the isolation of functional centromeric DNA. Proc Natl Acad Sci U S A (1981) 2.45
Instability of dicentric plasmids in yeast. Proc Natl Acad Sci U S A (1983) 2.16
Deletion of plasmid sequences during Saccharomyces cerevisiae transformation. J Bacteriol (1984) 1.25
Initial sequencing and analysis of the human genome. Nature (2001) 212.86
Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science (1995) 88.48
Screening lambdagt recombinant clones by hybridization to single plaques in situ. Science (1977) 83.82
Construction of a genetic linkage map in man using restriction fragment length polymorphisms. Am J Hum Genet (1980) 75.25
Life with 6000 genes. Science (1996) 41.51
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science (1999) 36.25
Efficient isolation of genes by using antibody probes. Proc Natl Acad Sci U S A (1983) 34.00
High-frequency transformation of yeast: autonomous replication of hybrid DNA molecules. Proc Natl Acad Sci U S A (1979) 26.51
Parallel human genome analysis: microarray-based expression monitoring of 1000 genes. Proc Natl Acad Sci U S A (1996) 24.18
Separation of large DNA molecules by contour-clamped homogeneous electric fields. Science (1986) 21.33
Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 20.61
A genome-wide transcriptional analysis of the mitotic cell cycle. Mol Cell (1998) 19.67
Studies on the cleavage of bacteriophage lambda DNA with EcoRI Restriction endonuclease. J Mol Biol (1975) 19.67
Sterile host yeasts (SHY): a eukaryotic system of biological containment for recombinant DNA experiments. Gene (1979) 19.39
Yeast RNA polymerase II genes: isolation with antibody probes. Science (1983) 17.91
Replacement of chromosome segments with altered DNA sequences constructed in vitro. Proc Natl Acad Sci U S A (1979) 17.55
Analysis of chromosomal integration and deletions of yeast plasmids. Nucleic Acids Res (1977) 16.66
Cleavage of DNA by R 1 restriction endonuclease generates cohesive ends. Proc Natl Acad Sci U S A (1972) 13.95
Genome sequence of an obligate intracellular pathogen of humans: Chlamydia trachomatis. Science (1998) 13.64
Evidence for transposition of dispersed repetitive DNA families in yeast. Cell (1979) 11.85
Rapid DNA isolations for enzymatic and hybridization analysis. Methods Enzymol (1980) 11.28
Centromeric DNA from Saccharomyces cerevisiae. J Mol Biol (1982) 9.64
Isolation and characterisation of a yeast chromosomal replicator. Nature (1979) 9.14
The composite genome of the legume symbiont Sinorhizobium meliloti. Science (2001) 9.11
Viable molecular hybrids of bacteriophage lambda and eukaryotic DNA. Proc Natl Acad Sci U S A (1974) 8.97
Functional genetic expression of eukaryotic DNA in Escherichia coli. Proc Natl Acad Sci U S A (1976) 8.92
Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss. Cell (1985) 8.78
RNA from the yeast transposable element Ty1 has both ends in the direct repeats, a structure similar to retrovirus RNA. Proc Natl Acad Sci U S A (1983) 8.61
Y chromosome sequence variation and the history of human populations. Nat Genet (2000) 8.34
Isolation of galactose-inducible DNA sequences from Saccharomyces cerevisiae by differential plaque filter hybridization. Cell (1979) 7.88
Functional selection and analysis of yeast centromeric DNA. Cell (1985) 7.74
Replication dynamics of the yeast genome. Science (2001) 7.56
Dissection of Mycobacterium tuberculosis antigens using recombinant DNA. Proc Natl Acad Sci U S A (1985) 7.46
The organization and transcription of the galactose gene cluster of Saccharomyces. J Mol Biol (1981) 7.44
The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell (1989) 7.00
Lambda YES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations. Proc Natl Acad Sci U S A (1991) 6.82
Deletion analysis of the Saccharomyces GAL gene cluster. Transcription from three promoters. J Mol Biol (1981) 6.79
Detection of numerous Y chromosome biallelic polymorphisms by denaturing high-performance liquid chromatography. Genome Res (1997) 6.73
A physical study by electron microscopy of the terminally reptitious, circularly permuted DNA from the coliphage particles of Escherichia coli 15. J Mol Biol (1970) 6.63
Genes for the major protein antigens of the leprosy parasite Mycobacterium leprae. Nature (1985) 6.54
Hybridization of RNA to double-stranded DNA: formation of R-loops. Proc Natl Acad Sci U S A (1976) 6.30
In vitro construction of bacteriophage lambda carrying segments of the Escherichia coli chromosome: selection of hybrids containing the gene for DNA ligase. Proc Natl Acad Sci U S A (1975) 5.95
Direct allelic variation scanning of the yeast genome. Science (1998) 5.90
Transcriptional regulation and function during the human cell cycle. Nat Genet (2001) 5.89
Comparative genomes of Chlamydia pneumoniae and C. trachomatis. Nat Genet (1999) 5.81
Arabidopsis and Nicotiana anthocyanin production activated by maize regulators R and C1. Science (1992) 5.79
Quantitative phenotypic analysis of yeast deletion mutants using a highly parallel molecular bar-coding strategy. Nat Genet (1996) 5.77
A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol Cell Biol (1987) 5.66
Yeast microarrays for genome wide parallel genetic and gene expression analysis. Proc Natl Acad Sci U S A (1997) 5.59
A study in evolution: the DNA base sequence homology between coliphages T7 and T3. J Mol Biol (1971) 5.42
Rain-, wind-, and touch-induced expression of calmodulin and calmodulin-related genes in Arabidopsis. Cell (1990) 5.22
T antigen binds to simian virus 40 DNA at the origin of replication. Proc Natl Acad Sci U S A (1975) 5.22
Genomic profiling of drug sensitivities via induced haploinsufficiency. Nat Genet (1999) 5.06
Unique arrangement of coding sequences for 5 S, 5.8 S, 18 S and 25 S ribosomal RNA in Saccharomyces cerevisiae as determined by R-loop and hybridization analysis. J Mol Biol (1978) 5.02
Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3). Proc Natl Acad Sci U S A (1977) 4.86
Discovery and analysis of inflammatory disease-related genes using cDNA microarrays. Proc Natl Acad Sci U S A (1997) 4.82
Eukaryotic DNA segments capable of autonomous replication in yeast. Proc Natl Acad Sci U S A (1980) 4.73
The core meiotic transcriptome in budding yeasts. Nat Genet (2000) 4.64
Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy. Cell (1990) 4.59
A family of versatile centromeric vectors designed for use in the sectoring-shuffle mutagenesis assay in Saccharomyces cerevisiae. Gene (1988) 4.50
An electrophoretic karyotype of Neurospora crassa. Mol Cell Biol (1988) 4.46
Rapid induction of specific mRNAs by auxin in pea epicotyl tissue. J Mol Biol (1985) 4.42
Transcription of the his3 gene region in Saccharomyces cerevisiae. J Mol Biol (1981) 4.30
Resolution of DNA molecules greater than 5 megabases by contour-clamped homogeneous electric fields. Nucleic Acids Res (1987) 4.28
Microarrays: biotechnology's discovery platform for functional genomics. Trends Biotechnol (1998) 4.25
Tetrad analysis possible in Arabidopsis with mutation of the QUARTET (QRT) genes. Science (1994) 4.19
Direction of chromosome rearrangements in Saccharomyces cerevisiae by use of his3 recombinational substrates. Mol Cell Biol (1988) 4.06
Nitrate reductase from squash: cDNA cloning and nitrate regulation. Proc Natl Acad Sci U S A (1986) 3.96
Physical mapping of large DNA by chromosome fragmentation. Proc Natl Acad Sci U S A (1988) 3.95
S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase. Nature (1993) 3.92
The TTG gene is required to specify epidermal cell fate and cell patterning in the Arabidopsis root. Dev Biol (1994) 3.83
Deletion mutants of bacteriophage lambda. 3. Physical structure of att-phi. J Mol Biol (1971) 3.76
Plant defense genes are regulated by ethylene. Proc Natl Acad Sci U S A (1987) 3.62
Two genes differentially regulated in the cell cycle and by DNA-damaging agents encode alternative regulatory subunits of ribonucleotide reductase. Genes Dev (1990) 3.61
Isolation of the gene encoding yeast DNA polymerase I. Cell (1985) 3.59
Letter: Potential biohazards of recombinant DNA molecules. Science (1974) 3.45
A conditional sterile mutation eliminates surface components from Arabidopsis pollen and disrupts cell signaling during fertilization. Genes Dev (1993) 3.43
Sink or swim: strategies for cost-efficient diving by marine mammals. Science (2000) 3.40
Electron-microscopic visualization of deletion mutations. Proc Natl Acad Sci U S A (1968) 3.35
A physical, genetic and transcriptional map of the cloned his3 gene region of Saccharomyces cerevisiae. J Mol Biol (1980) 3.35
Targeted selection of recombinant clones through gene dosage effects. Proc Natl Acad Sci U S A (1983) 3.33
Studies on the transposable element Ty1 of yeast. I. RNA homologous to Ty1. II. Recombination and expression of Ty1 and adjacent sequences. Cold Spring Harb Symp Quant Biol (1981) 3.27
Lambda gt 11: gene isolation with antibody probes and other applications. Methods Enzymol (1987) 3.17
Translation initiation and ribosomal biogenesis: involvement of a putative rRNA helicase and RPL46. Science (1990) 3.13
Homology and structural relationships between the dimeric and monomeric circular forms of mitochondrial DNA from human leukemic leukocytes. J Mol Biol (1970) 3.07
Recombination of dispersed repeated DNA sequences in yeast. Science (1980) 2.97
Identification and isolation of the gene encoding the small subunit of ribonucleotide reductase from Saccharomyces cerevisiae: DNA damage-inducible gene required for mitotic viability. Mol Cell Biol (1987) 2.97
RPC40, a unique gene for a subunit shared between yeast RNA polymerases A and C. Cell (1987) 2.96
HD-Zip proteins: members of an Arabidopsis homeodomain protein superfamily. Proc Natl Acad Sci U S A (1992) 2.94
Cloning of the yeast ribosomal DNA repeat unit in SstI and HindIII lambda vectors using genetic and physical size selections. J Mol Biol (1978) 2.87
G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev (1995) 2.77
The SLT2(MPK1) MAP kinase is activated during periods of polarized cell growth in yeast. EMBO J (1996) 2.74
Promotor mutants of the yeast his3 gene. J Mol Biol (1981) 2.73
Transcription interferes with elements important for chromosome maintenance in Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.65
Epidermal cell fate determination in Arabidopsis: patterns defined by a steroid-inducible regulator. Science (1994) 2.65
Population genetic implications from sequence variation in four Y chromosome genes. Proc Natl Acad Sci U S A (2000) 2.62
Nucleotide sequence and predicted functions of the entire Sinorhizobium meliloti pSymA megaplasmid. Proc Natl Acad Sci U S A (2001) 2.59