Published in Bioessays on February 01, 1987
Sex-specific expression of alternative transcripts in Drosophila. Genome Biol (2006) 1.53
The complex set of late transcripts from the Drosophila sex determination gene sex-lethal encodes multiple related polypeptides. Mol Cell Biol (1991) 1.51
Transcriptional and posttranscriptional regulation contributes to the sex-regulated expression of two sequence-related genes at the janus locus of Drosophila melanogaster. Mol Cell Biol (1989) 1.03
Sex-specific control of Drosophila melanogaster yolk protein 1 gene expression is limited to transcription. Mol Cell Biol (1988) 1.01
The doublesex locus of Drosophila melanogaster and its flanking regions: a cytogenetic analysis. Genetics (1991) 0.95
Genetics on the Fly: A Primer on the Drosophila Model System. Genetics (2015) 0.83
The genome sequence of Drosophila melanogaster. Science (2000) 74.32
Segmental aneuploidy and the genetic gross structure of the Drosophila genome. Genetics (1972) 22.68
The genetic control of meiosis. Annu Rev Genet (1976) 10.21
Genetic analysis of sex chromosomal meiotic mutants in Drosophilia melanogaster. Genetics (1972) 7.86
Sex and the single cell. I. On the action of major loci affecting sex determination in Drosophila melanogaster. Genetics (1980) 4.81
Drosophila doublesex gene controls somatic sexual differentiation by producing alternatively spliced mRNAs encoding related sex-specific polypeptides. Cell (1989) 4.15
Genes controlling essential cell-cycle functions in Drosophila melanogaster. Genes Dev (1989) 3.50
SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes. J Biol Chem (1999) 3.35
Control of male sexual behavior and sexual orientation in Drosophila by the fruitless gene. Cell (1996) 3.30
Sex determination and dosage compensation in Drosophila melanogaster. Annu Rev Genet (1983) 3.01
The maleless protein associates with the X chromosome to regulate dosage compensation in Drosophila. Cell (1991) 2.98
Epidermal T lymphocytes and HLA-DR expression in psoriasis. Br J Dermatol (1984) 2.93
The control of alternative splicing at genes regulating sexual differentiation in D. melanogaster. Cell (1988) 2.83
T-cell subpopulations in the blood and skin of patients with psoriasis. Br J Dermatol (1984) 2.54
Regulation of sex-specific RNA splicing at the Drosophila doublesex gene: cis-acting mutations in exon sequences alter sex-specific RNA splicing patterns. Genes Dev (1990) 2.49
The rox1 and rox2 RNAs are essential components of the compensasome, which mediates dosage compensation in Drosophila. Mol Cell (1999) 2.40
The sex determination locus transformer-2 of Drosophila encodes a polypeptide with similarity to RNA binding proteins. Cell (1989) 2.39
Genetic controls of meiotic recombination and somatic DNA metabolism in Drosophila melanogaster. Proc Natl Acad Sci U S A (1976) 2.39
A P element containing suppressor of hairy-wing binding regions has novel properties for mutagenesis in Drosophila melanogaster. Genetics (1995) 2.38
The evolutionary dynamics of sex determination. Science (1998) 2.35
Paternal loss (pal): a meiotic mutant in Drosophila melanogaster causing loss of paternal chromosomes. Genetics (1975) 2.28
The Drosophila SR protein RBP1 contributes to the regulation of doublesex alternative splicing by recognizing RBP1 RNA target sequences. EMBO J (1995) 2.25
Regulation of doublesex pre-mRNA processing occurs by 3'-splice site activation. Genes Dev (1991) 2.21
Molecular characterization of the male-specific lethal-3 gene and investigations of the regulation of dosage compensation in Drosophila. Development (1995) 2.16
Eukaryotic DNA polymerases: proposal for a revised nomenclature. J Biol Chem (2001) 2.15
The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal. Development (1995) 2.13
Spatial and temporal patterns of E74 transcription during Drosophila development. Cell (1990) 2.11
The regulation of the Drosophila msl-2 gene reveals a function for Sex-lethal in translational control. Cell (1997) 2.09
Psoriasis: a T-cell-mediated autoimmune disease induced by streptococcal superantigens? Immunol Today (1995) 2.09
The doublesex proteins of Drosophila melanogaster bind directly to a sex-specific yolk protein gene enhancer. EMBO J (1991) 2.02
The Drosophila doublesex proteins share a novel zinc finger related DNA binding domain. EMBO J (1993) 2.00
The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes Dev (1992) 1.90
Molecular cloning of Drosophila mus308, a gene involved in DNA cross-link repair with homology to prokaryotic DNA polymerase I genes. Mol Cell Biol (1996) 1.79
The sex determination gene doublesex regulates the A/P organizer to direct sex-specific patterns of growth in the Drosophila genital imaginal disc. Dev Cell (2001) 1.79
Clearance of psoriasis with low dose cyclosporin. Br Med J (Clin Res Ed) (1986) 1.75
Autoregulation and multifunctionality among trans-acting factors that regulate alternative pre-mRNA processing. J Biol Chem (1992) 1.71
Cloning and characterization of the scarlet gene of Drosophila melanogaster. Genetics (1989) 1.68
The dosage compensation system of Drosophila is co-opted by newly evolved X chromosomes. Nature (1996) 1.68
DNA repair in Drosophila: insights from the Drosophila genome sequence. J Cell Biol (2000) 1.65
Isolation of RRM-type RNA-binding protein genes and the analysis of their relatedness by using a numerical approach. Mol Cell Biol (1993) 1.64
Behavioral and neurobiological implications of sex-determining factors in Drosophila. Dev Genet (1994) 1.63
The evolution of dosage-compensation mechanisms. Bioessays (2000) 1.62
Autoregulation of the splicing of transcripts from the transformer-2 gene of Drosophila. Genes Dev (1991) 1.60
Psoriasis and streptococci: the natural selection of psoriasis revisited. Br J Dermatol (2009) 1.58
The maternal and zygotic control of development by cinnamon, a new mutant in Drosophila melanogaster. Dev Biol (1973) 1.57
A molecular analysis of transformer, a gene in Drosophila melanogaster that controls female sexual differentiation. Cell (1987) 1.54
Regulation of sex-specific selection of fruitless 5' splice sites by transformer and transformer-2. Mol Cell Biol (1998) 1.53
The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis. Br J Dermatol (1987) 1.53
Sex-specific regulation of yolk protein gene expression in Drosophila. Cell (1985) 1.52
Effects of recombination-deficient and repair-deficient loci on meiotic and mitotic chromosome behavior in Drosophila melanogaster. Basic Life Sci (1980) 1.50
The lethal(1)TW-6cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-binding domain. Genetics (1991) 1.48
Purification and characterization of a kanamycin nucleotidyltransferase from plasmid pUB110-carrying cells of Bacillus subtilis. J Bacteriol (1980) 1.43
Reconstitution studies show that rifampicin resistance is determined by the largest polypeptide of Bacillus subtilis RNA polymerase. J Biol Chem (1977) 1.43
Long-term cyclosporin for psoriasis. Br J Dermatol (1989) 1.42
The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans. J Neurosci (1993) 1.41
Molecular genetic dissection of the sex-specific and vital functions of the Drosophila melanogaster sex determination gene fruitless. Genetics (2001) 1.39
Cyclosporin toxicity. Lancet (1990) 1.38
The Drosophila E74 gene is required for metamorphosis and plays a role in the polytene chromosome puffing response to ecdysone. Development (1995) 1.34
Relationships among chromatid interchanges, sister chromatid exchanges, and meiotic recombination in Drosophila melanogaster. Proc Natl Acad Sci U S A (1980) 1.32
Sex determination in Drosophila melanogaster: analysis of transformer-2, a sex-transforming locus. Proc Natl Acad Sci U S A (1982) 1.30
The mutability of the minute loci of Drosophila melanogaster with ethyl methanesulfonate. Mutat Res (1976) 1.29
Control of sexual differentiation in Drosophila melanogaster. Cold Spring Harb Symp Quant Biol (1985) 1.29
Functional and genetic characterization of the oligomerization and DNA binding properties of the Drosophila doublesex proteins. Genetics (1996) 1.29
napts, a mutation affecting sodium channel activity in Drosophila, is an allele of mle, a regulator of X chromosome transcription. Cell (1991) 1.29
Epidermal T lymphocytes and dendritic cells in chronic plaque psoriasis: the effects of PUVA treatment. Clin Exp Immunol (1985) 1.29
Sequences expressed sex-specifically in Drosophila melanogaster adults. Dev Biol (1987) 1.28
Regulation of the sex-specific binding of the maleless dosage compensation protein to the male X chromosome in Drosophila. Cell (1993) 1.27
Mutations in genes encoding essential mitotic functions in Drosophila melanogaster. Genetics (1985) 1.26
Alternative splicing of the sex determination gene transformer-2 is sex-specific in the germ line but not in the soma. Genes Dev (1990) 1.25
Evidence that MSL-mediated dosage compensation in Drosophila begins at blastoderm. Development (1996) 1.23
Sexual behavior: its genetic control during development and adulthood in Drosophila melanogaster. Proc Natl Acad Sci U S A (1987) 1.22
A positive role in differentiation for the male doublesex protein of Drosophila. Dev Biol (1993) 1.21
Developmental and regional expression of thyroid hormone receptor genes during Xenopus metamorphosis. Development (1991) 1.19
beta' subunit of bacterial RNA polymerase is responsible for streptolydigin resistance in Bacillus subtilis. Nature (1978) 1.18
The dual functions of a sex determination gene in Drosophila melanogaster. Dev Biol (1983) 1.18
Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila. Development (1993) 1.17
Dosage compensation and chromatin structure in Drosophila. Curr Opin Genet Dev (1996) 1.17
The Drosophila sex determination hierarchy modulates wingless and decapentaplegic signaling to deploy dachshund sex-specifically in the genital imaginal disc. Development (2001) 1.15
Aberrant splicing and altered spatial expression patterns in fruitless mutants of Drosophila melanogaster. Genetics (2000) 1.15
Region-specific effects on chromosome integrity of mutations at essential loci in Drosophila melanogaster. Proc Natl Acad Sci U S A (1982) 1.15
A gene controlling condensation of heterochromatin in Drosophila melanogaster. Science (1983) 1.15
The effects of mutagen-sensitive mutants of Drosophila melanogaster in nonmutagenized cells. Genetics (1979) 1.15
Origin and evolution of the regulatory gene male-specific lethal-3. Mol Biol Evol (2000) 1.08
Damage control: the pleiotropy of DNA repair genes in Drosophila melanogaster. Genetics (1998) 1.08
A negative feedback mechanism revealed by functional analysis of the alternative isoforms of the Drosophila splicing regulator transformer-2. Genetics (1996) 1.07
Renal function and biopsy findings after 5 years' treatment with low-dose cyclosporin for psoriasis. Br J Dermatol (1993) 1.06
How flies make one equal two: dosage compensation in Drosophila. Trends Genet (1994) 1.05
Autoinduction of nuclear receptor genes and its significance. J Steroid Biochem Mol Biol (1993) 1.04
Dosage compensation rox! Curr Opin Cell Biol (2000) 1.04
Restricted T-cell receptor V beta gene usage in the skin of patients with guttate and chronic plaque psoriasis. Br J Dermatol (1993) 1.04
A genetic analysis of intersex, a gene regulating sexual differentiation in Drosophila melanogaster females. Genetics (1995) 1.03
Nucleotide excision repair endonuclease genes in Drosophila melanogaster. Mutat Res (2000) 1.03
The effects of topical treatment with steroids or dithranol on epidermal T lymphocytes and dendritic cells in psoriasis. Scand J Immunol (1985) 1.01
Compartmental organization of the Drosophila genital imaginal discs. Development (1997) 1.00
Cytogenetic analysis of chromosome region 73AD of Drosophila melanogaster. Genetics (1990) 1.00
A new DNA polymerase species from Drosophila melanogaster: a probable mus308 gene product. Mutat Res (1999) 0.99
Specificity of immunoglobulin E in coccidioidomycosis and correlation with disease involvement. Infect Immun (1982) 0.96
Epidermal rupture is the initiating factor for the Koebner response in psoriasis. Acta Derm Venereol (1990) 0.96
Induction of apoptosis in the germline and follicle layer of Drosophila egg chambers. Mech Dev (1999) 0.93