Published in J Clin Invest on May 01, 1987
Host Response to Infection and Treatment in Lymphatic Filarial Disease in India | NCT00342576
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset. J Clin Invest (1993) 2.00
In utero exposure to helminth and mycobacterial antigens generates cytokine responses similar to that observed in adults. J Clin Invest (1997) 1.64
Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1. J Infect Dis (2009) 1.43
Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state. J Clin Invest (1992) 1.24
Ivermectin-facilitated immunity in onchocerciasis. Reversal of lymphocytopenia, cellular anergy and deficient cytokine production after single treatment. Clin Exp Immunol (1992) 1.22
Immunopathogenesis of lymphatic filarial disease. Semin Immunopathol (2012) 1.19
Regulation of parasite antigen-driven immune responses by interleukin-10 (IL-10) and IL-12 in lymphatic filariasis. Infect Immun (1997) 1.09
Impact of filarial infections on coincident intracellular pathogens: Mycobacterium tuberculosis and Plasmodium falciparum. Curr Opin HIV AIDS (2012) 1.05
Diminished monocyte function in microfilaremic patients with lymphatic filariasis and its relationship to altered lymphoproliferative responses. Infect Immun (2005) 1.05
IL-4-, TGF-β-, and IL-1-dependent expansion of parasite antigen-specific Th9 cells is associated with clinical pathology in human lymphatic filariasis. J Immunol (2013) 0.99
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Insights into the pathogenesis of disease in human lymphatic filariasis. Lymphat Res Biol (2013) 0.96
Transcriptional control of impaired Th1 responses in patent lymphatic filariasis by T-box expressed in T cells and suppressor of cytokine signaling genes. Infect Immun (2005) 0.95
Immunoregulation in onchocerciasis. Functional and phenotypic abnormalities of lymphocyte subsets and changes with therapy. J Clin Invest (1991) 0.95
Elimination of helminth infection restores HIV-1C vaccine-specific T cell responses independent of helminth-induced IL-10. Vaccine (2009) 0.93
Regulation of the host immune system by helminth parasites. J Allergy Clin Immunol (2016) 0.91
Regulatory T cell subsets in filarial infection and their function. Front Immunol (2013) 0.90
Lymphocyte subpopulations in Bancroftian filariasis: activated (DR+) CD8+ T cells in patients with chronic lymphatic obstruction. Clin Exp Immunol (1989) 0.90
Infection outcome and cytokine gene expression in Brugia pahangi- infected gerbils (Meriones unguiculatus) sensitized with Brucella abortus. Infect Immun (2002) 0.87
Elevated adaptive immune responses are associated with latent infections of Wuchereria bancrofti. PLoS Negl Trop Dis (2012) 0.85
Differential antibody isotype reactivity to specific antigens in human lymphatic filariasis: gp15/400 preferentially induces immunoglobulin E (IgE), IgG4, and IgG2. Infect Immun (1995) 0.84
Expansion of parasite-specific CD4+ and CD8+ T cells expressing IL-10 superfamily cytokine members and their regulation in human lymphatic filariasis. PLoS Negl Trop Dis (2014) 0.84
Altered T cell memory and effector cell development in chronic lymphatic filarial infection that is independent of persistent parasite antigen. PLoS One (2011) 0.82
Impact of microfilaremia on maintenance of a hyporesponsive cellular immune response in Brugia-infected gerbils (Meriones unguiculatus). Infect Immun (1995) 0.81
Down regulation of macrophage activation in Brugia pahangi-infected jirds (Meriones unguiculatus). Infect Immun (1998) 0.80
Interleukin 1 (IL-1)- and IL-23-mediated expansion of filarial antigen-specific Th17 and Th22 cells in filarial lymphedema. Clin Vaccine Immunol (2014) 0.79
Immune responses to recombinant Brugia malayi pepsin inhibitor homolog (Bm-33) in patients with human lymphatic filariaisis. Parasitol Res (2010) 0.78
Looking beyond the induction of Th2 responses to explain immunomodulation by helminths. Parasite Immunol (2015) 0.76
The glomerular permeability determined by dextran clearance using Sephadex gel filtration. Scand J Clin Lab Invest (1968) 10.35
Continuous proliferation of murine antigen-specific helper T lymphocytes in culture. J Exp Med (1979) 7.20
The isolation and characterization of the human suppressor inducer T cell subset. J Immunol (1985) 6.69
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Absence of gamma interferon and interleukin 2 production during active visceral leishmaniasis. J Clin Invest (1985) 3.41
Specific cellular immune unresponsiveness in human filariasis. Immunology (1977) 2.23
Immunological aspects of lymphatic filariasis and onchocerciasis in man. Trans R Soc Trop Med Hyg (1984) 2.05
T cell enrichment and depletion of human peripheral blood mononuclear cell preparations. Unexpected findings in the study of the functional activities of the separated populations. J Immunol Methods (1982) 1.95
IgE responses in human filariasis. I. Quantitation of filaria-specific IgE. J Immunol (1981) 1.71
Immune responses in human infections with Brugia malayi: specific cellular unresponsiveness to filarial antigens. J Clin Invest (1980) 1.68
An analysis of in vitro T cell responsiveness in lepromatous leprosy. J Exp Med (1985) 1.52
Antigen-specific suppressor T lymphocytes in human lymphatic filariasis. N Engl J Med (1982) 1.47
Positive correlation between degree of parasitemia, interferon titers, and natural killer cell activity in Plasmodium falciparum-infected children. J Immunol (1981) 1.38
Prenatal allergic sensitization to helminth antigens in offspring of parasite-infected mothers. J Clin Invest (1983) 1.25
Endemic filariasis on a Pacific Island. II. Immunologic aspects: immunoglobulin, complement, and specific antifilarial IgG, IgM, and IgE antibodies. Am J Trop Med Hyg (1982) 1.19
Correction of interleukin-2 production in patients with systemic lupus erythematosus by removal of spontaneously activated suppressor cells. J Clin Invest (1985) 1.18
Familial predisposition to filarial infection--not linked to HLA-A or-B locus specificities. Acta Trop (1981) 1.15
Brugia malayi: relationship between anti-sheath antibodies and amicrofilaremia in natives living in an endemic area of South Kalimantan, Borneo. Am J Trop Med Hyg (1980) 1.14
A monoclonal antibody-based immunoradiometric assay for detection of circulating antigen in Bancroftian filariasis. J Immunol (1985) 1.14
Parasite antigen-specific human T cell lines and clones. Major histocompatibility complex restriction and B cell helper function. J Clin Invest (1984) 0.90
IgM antibody to filarial antigens in human cord blood: possibility of transplacental infection. Trans R Soc Trop Med Hyg (1980) 0.89
Genetic association of murine susceptibility to Brugia malayi microfilaraemia. Parasite Immunol (1983) 0.88
Immunoradiometric assay for detection of filarial antigens in human serum. J Immunol (1984) 0.86
Immediate and delayed hypersensitivity skin test responses to the Dirofilaria immitis filarial skin test (Sawada) antigen in Wuchereria bancrofti filariasis. Am J Trop Med Hyg (1980) 0.85
Failure of diethylcarbamazine as a provocative test in subperiodic Wuchereria bancrofti filariasis. Trans R Soc Trop Med Hyg (1978) 0.85
Opposing effects of filariasis and chronic malaria on immunoregulatory T lymphocytes. Diagn Immunol (1983) 0.81
Human B-cell proliferation in response to recombinant interleukin 2 is not due to T-cell help. Cell Immunol (1985) 0.79
The presence of blocking factors in Brugia malayi microfilaraemic patients. Immunology (1984) 0.79
Malnutrition and parasitic helminth infections. Parasitology (2000) 3.53
CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha. J Immunol (1999) 3.32
An inter-familial outbreak of Yersinia enterocolitica enteritis. N Engl J Med (1973) 3.14
In vivo cytokine profiles in patients with kala-azar. Marked elevation of both interleukin-10 and interferon-gamma. J Clin Invest (1993) 2.84
The global programme to eliminate lymphatic filariasis. Trop Med Int Health (2000) 2.58
Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence. J Immunol (2006) 2.29
Specific cellular immune unresponsiveness in human filariasis. Immunology (1977) 2.23
Adaptation of innate lymphoid cells to a micronutrient deficiency promotes type 2 barrier immunity. Science (2014) 2.20
A controlled trial of ivermectin and diethylcarbamazine in lymphatic filariasis. N Engl J Med (1990) 2.11
Human infection with Ascaris lumbricoides is associated with suppression of the interleukin-2 response to recombinant cholera toxin B subunit following vaccination with the live oral cholera vaccine CVD 103-HgR. Infect Immun (2001) 2.09
Immunological aspects of lymphatic filariasis and onchocerciasis in man. Trans R Soc Trop Med Hyg (1984) 2.05
Human infection with Ascaris lumbricoides is associated with a polarized cytokine response. J Infect Dis (2000) 2.05
Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset. J Clin Invest (1993) 2.00
Long-term effect of prenatal exposure to maternal microfilaraemia on immune responsiveness to filarial parasite antigens. Lancet (1994) 1.92
Prominence of IgG4 in the IgG antibody response to human filariasis. J Immunol (1985) 1.91
An immunogenic Onchocerca volvulus antigen: a specific and early marker of infection. Science (1991) 1.86
Immunity to onchocerciasis: identification of a putatively immune population in a hyperendemic area of Ecuador. J Infect Dis (1994) 1.85
Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity (1997) 1.84
Enhanced diagnostic specificity in human filariasis by IgG4 antibody assessment. J Infect Dis (1988) 1.83
Alternatively activated and immunoregulatory monocytes in human filarial infections. J Infect Dis (2009) 1.82
Albendazole treatment of children with ascariasis enhances the vibriocidal antibody response to the live attenuated oral cholera vaccine CVD 103-HgR. J Infect Dis (2000) 1.82
Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunol (2001) 1.78
Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10. J Infect Dis (1998) 1.76
Regulation of parasite-induced eosinophilia: selectively increased interleukin 5 production in helminth-infected patients. J Exp Med (1990) 1.71
IgE responses in human filariasis. I. Quantitation of filaria-specific IgE. J Immunol (1981) 1.71
Interferon-gamma in the management of infectious diseases. Ann Intern Med (1995) 1.68
Tropical medicine. BMJ (2000) 1.67
Modulation of the host response in human schistosomiasis. I. Adherent suppressor cells that inhibit lymphocyte proliferative responses to parasite antigens. J Immunol (1979) 1.61
A rapid-format antibody card test for diagnosis of onchocerciasis. J Infect Dis (2000) 1.53
Development and standardization of a rapid, PCR-based method for the detection of Wuchereria bancrofti in mosquitoes, for xenomonitoring the human prevalence of bancroftian filariasis. Ann Trop Med Parasitol (2002) 1.53
Cutting edge: diminished T cell TLR expression and function modulates the immune response in human filarial infection. J Immunol (2006) 1.52
Immunologic responses to repeated ivermectin treatment in patients with onchocerciasis. J Infect Dis (1991) 1.52
High levels of spontaneous and parasite antigen-driven interleukin-10 production are associated with antigen-specific hyporesponsiveness in human lymphatic filariasis. J Infect Dis (1996) 1.51
Loiasis in endemic and nonendemic populations: immunologically mediated differences in clinical presentation. J Infect Dis (1991) 1.49
Heterozygosity for a defective gene for CC chemokine receptor 5 is not the sole determinant for the immunologic and virologic phenotype of HIV-infected long-term nonprogressors. J Clin Invest (1997) 1.46
Loa loa infection in temporary residents of endemic regions: recognition of a hyperresponsive syndrome with characteristic clinical manifestations. J Infect Dis (1986) 1.45
Control of allergic reactivity in human filariasis. Predominant localization of blocking antibody to the IgG4 subclass. J Immunol (1992) 1.44
Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1. J Infect Dis (2009) 1.43
Flow cytometric analysis for cytokine production identifies T helper 1, T helper 2, and T helper 0 cells within the human CD4+CD27- lymphocyte subpopulation. J Immunol (1995) 1.42
An analysis of the safety of the single dose, two drug regimens used in programmes to eliminate lymphatic filariasis. Parasitology (2000) 1.42
Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro. J Infect Dis (2000) 1.41
The acquisition and loss of antigen-specific cellular immune responsiveness in acute and chronic schistosomiasis in man. Clin Exp Immunol (1978) 1.40
Lymphatic filariasis: an infection of childhood. Trop Med Int Health (2001) 1.40
IL-4- and IL-5-secreting lymphocyte populations are preferentially stimulated by parasite-derived antigens in human tissue invasive nematode infections. J Immunol (1993) 1.39
Tropical pulmonary eosinophilia. Annu Rev Med (1992) 1.38
Onchocerciasis and immunity in humans: enhanced T cell responsiveness to parasite antigen in putatively immune individuals. J Infect Dis (1988) 1.36
IgE responses in human filariasis. IV. Parallel antigen recognition by IgE and IgG4 subclass antibodies. J Immunol (1986) 1.35
Onchocerciasis in endemic and nonendemic populations: differences in clinical presentation and immunologic findings. J Infect Dis (1994) 1.34
Parallel regulation of IL-4 and IL-5 in human helminth infections. J Immunol (1992) 1.33
Genetic polymorphisms in molecules of innate immunity and susceptibility to infection with Wuchereria bancrofti in South India. Genes Immun (2001) 1.32
IgG antibody subclasses in human filariasis. Differential subclass recognition of parasite antigens correlates with different clinical manifestations of infection. J Immunol (1987) 1.32
Diminished expression and function of TLR in lymphatic filariasis: a novel mechanism of immune dysregulation. J Immunol (2005) 1.31
Immunity to onchocerciasis: putative immune persons produce a Th1-like response to Onchocerca volvulus. J Infect Dis (1995) 1.31
Efficacy and sustainability of a footcare programme in preventing acute attacks of adenolymphangitis in Brugian filariasis. Trop Med Int Health (2002) 1.30
A polymerase chain reaction assay for detection of the parasite Wuchereria bancrofti in human blood samples. Am J Trop Med Hyg (1996) 1.30
Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T cells. PLoS Negl Trop Dis (2009) 1.30
Regulation of the immune response in lymphatic filariasis and onchocerciasis. Immunol Today (1991) 1.29
Identification of recombinant filarial proteins capable of inducing polyclonal and antigen-specific IgE and IgG4 antibodies. J Immunol (1995) 1.28
Filarial parasite-specific T cell lines: induction of IgE synthesis. J Immunol (1985) 1.26
Prenatal allergic sensitization to helminth antigens in offspring of parasite-infected mothers. J Clin Invest (1983) 1.25
Schistosome infections in humans: perspectives and recent findings. NIH conference. Ann Intern Med (1982) 1.25
Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state. J Clin Invest (1992) 1.24
Polymerase chain reaction-based diagnosis of Onchocerca volvulus infection: improved detection of patients with onchocerciasis. J Infect Dis (1994) 1.24
A preliminary study of filariasis related acute adenolymphangitis with special reference to precipitating factors and treatment modalities. Southeast Asian J Trop Med Public Health (1995) 1.23
Eosinophilia in Southeast Asian refugees: evaluation at a referral center. J Infect Dis (1987) 1.22
Renal abnormalities in microfilaremic patients with Bancroftian filariasis. Am J Trop Med Hyg (1992) 1.20
A recombinant antigen-based IgG4 ELISA for the specific and sensitive detection of Brugia malayi infection. Trans R Soc Trop Med Hyg (2001) 1.20
Endemic filariasis on a Pacific Island. II. Immunologic aspects: immunoglobulin, complement, and specific antifilarial IgG, IgM, and IgE antibodies. Am J Trop Med Hyg (1982) 1.19
Frequency analysis of IgE-secreting B lymphocytes in persons with normal or elevated serum IgE levels. J Immunol (1991) 1.19
Multicentre laboratory evaluation of Brugia Rapid dipstick test for detection of brugian filariasis. Trop Med Int Health (2003) 1.18
IL-12p70 production by Leishmania major-harboring human dendritic cells is a CD40/CD40 ligand-dependent process. J Immunol (2000) 1.18
Regulation of immunoglobulin production in hyperimmunoglobulin E recurrent-infection syndrome by interferon gamma. Proc Natl Acad Sci U S A (1989) 1.18
The Mazzotti reaction following treatment of onchocerciasis with diethylcarbamazine: clinical severity as a function of infection intensity. Am J Trop Med Hyg (1985) 1.17
A qualitative study of the perceptions, practices and socio-psychological suffering related to chronic brugian filariasis in Kerala, southern India. Ann Trop Med Parasitol (2003) 1.17
Prevention of acute adenolymphangitis in brugian filariasis: comparison of the efficacy of ivermectin and diethylcarbamazine, each combined with local treatment of the affected limb. Ann Trop Med Parasitol (1998) 1.17
Human onchocerciasis and tetanus vaccination: impact on the postvaccination antitetanus antibody response. Infect Immun (1999) 1.16