Published in J Immunol on August 02, 2013
Host Response to Infection and Treatment in Filarial Diseases | NCT00001230
Effect of Albendazole Dose on Clearance of Filarial Worms | NCT00375583
Plasticity of human CD4 T cell subsets. Front Immunol (2014) 1.25
The development and in vivo function of T helper 9 cells. Nat Rev Immunol (2015) 1.18
Dectin-1-activated dendritic cells trigger potent antitumour immunity through the induction of Th9 cells. Nat Commun (2016) 0.84
Th9/IL-9 profile in human echinococcosis: their involvement in immune response during infection by Echinococcus granulosus. Mediators Inflamm (2014) 0.82
Filarial infection modulates the immune response to Mycobacterium tuberculosis through expansion of CD4+ IL-4 memory T cells. J Immunol (2015) 0.80
The Potential Role of Th9 Cell Related Cytokine and Transcription Factors in Patients with Hepatic Alveolar Echinococcosis. J Immunol Res (2015) 0.77
Serum Interleukin (IL)-9 and IL-10, but not T-Helper 9 (Th9) Cells, are Associated With Survival of Patients With Acute-on-Chronic Hepatitis B Liver Failure. Medicine (Baltimore) (2016) 0.75
Bridging the divide between pathogenesis and detection in lymphedema. Semin Cell Dev Biol (2014) 0.75
Modulation of CD4+ and CD8+ T-Cell Function by Interleukin 19 and Interleukin 24 During Filarial Infections. J Infect Dis (2015) 0.75
TH9 cell differentiation, transcriptional control and function in inflammation, autoimmune diseases and cancer. Oncotarget (2016) 0.75
Induction of specific T helper-9 cells to inhibit glioma cell growth. Oncotarget (2017) 0.75
Human umbilical cord mesenchymal stem cells increase interleukin-9 production of CD4(+) T cells. Exp Ther Med (2017) 0.75
Analysis of the changes in Th9 cells and related cytokines in the peripheral blood of spontaneous urticaria patients. Biomed Rep (2017) 0.75
Mycobacteria induce TPL-2 mediated IL-10 in IL-4-generated alternatively activated macrophages. PLoS One (2017) 0.75
IL-9 and Th9 cells in health and diseases-From tolerance to immunopathology. Cytokine Growth Factor Rev (2017) 0.75
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 6.76
IL-4 inhibits TGF-beta-induced Foxp3+ T cells and, together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol (2008) 6.41
Mast cells are essential intermediaries in regulatory T-cell tolerance. Nature (2006) 5.49
Th17 cell differentiation: the long and winding road. Immunity (2008) 5.40
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol (2010) 3.97
Th1, Th17, and Th9 effector cells induce experimental autoimmune encephalomyelitis with different pathological phenotypes. J Immunol (2009) 3.88
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells. Immunity (2010) 3.64
IL-9 induces differentiation of TH17 cells and enhances function of FoxP3+ natural regulatory T cells. Proc Natl Acad Sci U S A (2009) 3.31
IL-9 as a mediator of Th17-driven inflammatory disease. J Exp Med (2009) 2.78
IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development. Immunity (2000) 2.74
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells. Nat Med (2012) 2.11
Regulation of human Th9 differentiation by type I interferons and IL-21. Immunol Cell Biol (2010) 1.99
Activin A and TGF-β promote T(H)9 cell-mediated pulmonary allergic pathology. J Allergy Clin Immunol (2012) 1.98
Th9 and allergic disease. Immunology (2009) 1.97
Cellular sources and immune functions of interleukin-9. Nat Rev Immunol (2010) 1.92
Interleukin-9 is involved in host protective immunity to intestinal nematode infection. Eur J Immunol (1997) 1.87
Enhanced diagnostic specificity in human filariasis by IgG4 antibody assessment. J Infect Dis (1988) 1.83
Th9 cells promote antitumor immune responses in vivo. J Clin Invest (2012) 1.80
Regulation of the immune response in lymphatic filariasis: perspectives on acute and chronic infection with Wuchereria bancrofti in South India. Parasite Immunol (2001) 1.78
Th9 cells: differentiation and disease. Immunol Rev (2013) 1.61
Anti-IL-9 vaccination prevents worm expulsion and blood eosinophilia in Trichuris muris-infected mice. Proc Natl Acad Sci U S A (2000) 1.46
Interleukin-9 is required for allergic airway inflammation mediated by the cytokine TSLP. Immunity (2013) 1.43
TGF-beta induces IL-9 production from human Th17 cells. J Immunol (2010) 1.40
Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T cells. PLoS Negl Trop Dis (2009) 1.30
Parasite-specific anergy in human filariasis. Insights after analysis of parasite antigen-driven lymphokine production. J Clin Invest (1987) 1.28
Immunopathogenesis of lymphatic filarial disease. Semin Immunopathol (2012) 1.19
The symphony of the ninth: the development and function of Th9 cells. Curr Opin Immunol (2012) 1.12
The many lives of IL-9: a question of survival? Nat Immunol (2012) 1.11
Predisposition to the development of IL-9-secreting T cells in atopic infants. J Allergy Clin Immunol (2011) 1.10
Differentiation and recruitment of Th9 cells stimulated by pleural mesothelial cells in human Mycobacterium tuberculosis infection. PLoS One (2012) 1.08
Maturation-related histone modifications in the PU.1 promoter regulate Th9-cell development. Blood (2012) 1.02
Increased interleukin‑9 and CD4+IL-9+ T cells in patients with systemic lupus erythematosus. Mol Med Rep (2013) 1.00
The unique features of Th9 cells and their products. Crit Rev Immunol (2012) 1.00
Th9: a new player in asthma pathogenesis? J Asthma (2011) 0.94
Differentiation and immune regulation of IL-9-producing CD4+ T cells in malignant pleural effusion. Am J Respir Crit Care Med (2012) 0.90
Strongyloides stercoralis in the Immunocompromised Population. Clin Microbiol Rev (2004) 5.41
Draft genome of the filarial nematode parasite Brugia malayi. Science (2007) 5.28
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol (2009) 3.74
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. J Allergy Clin Immunol (2006) 3.04
A luciferase immunoprecipitation systems assay enhances the sensitivity and specificity of diagnosis of Strongyloides stercoralis infection. J Infect Dis (2008) 2.65
Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood (2003) 2.65
Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence. J Immunol (2006) 2.29
Allergic symptoms, atopy, and geohelminth infections in a rural area of Ecuador. Am J Respir Crit Care Med (2003) 2.28
Use of high-dose, twice-yearly albendazole and ivermectin to suppress Wuchereria bancrofti microfilarial levels. Clin Infect Dis (2010) 2.23
A randomized trial of doxycycline for Mansonella perstans infection. N Engl J Med (2009) 2.21
The role of eosinophils in host defense against helminth parasites. J Allergy Clin Immunol (2004) 2.13
Anti-desmoglein-1 antibodies in onchocerciasis, leishmaniasis and Chagas disease suggest a possible etiological link to Fogo selvagem. J Invest Dermatol (2004) 1.98
A four-antigen mixture for rapid assessment of Onchocerca volvulus infection. PLoS Negl Trop Dis (2009) 1.89
Brugia malayi excreted/secreted proteins at the host/parasite interface: stage- and gender-specific proteomic profiling. PLoS Negl Trop Dis (2009) 1.88
Alternatively activated and immunoregulatory monocytes in human filarial infections. J Infect Dis (2009) 1.82
Field applicability of a rapid-format anti-Ov-16 antibody test for the assessment of onchocerciasis control measures in regions of endemicity. J Infect Dis (2006) 1.79
Improved diagnosis of Strongyloides stercoralis using recombinant antigen-based serologies in a community-wide study in northern Argentina. Clin Vaccine Immunol (2010) 1.70
Reduced risk of atopy among school-age children infected with geohelminth parasites in a rural area of the tropics. J Allergy Clin Immunol (2003) 1.65
Rapid, novel, specific, high-throughput assay for diagnosis of Loa loa infection. J Clin Microbiol (2008) 1.65
Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization. J Allergy Clin Immunol (2012) 1.58
Genomics of Loa loa, a Wolbachia-free filarial parasite of humans. Nat Genet (2013) 1.52
Cutting edge: diminished T cell TLR expression and function modulates the immune response in human filarial infection. J Immunol (2006) 1.52
Screening, prevention, and treatment for hyperinfection syndrome and disseminated infections caused by Strongyloides stercoralis. Curr Opin Infect Dis (2012) 1.50
Nodding syndrome. Emerg Infect Dis (2013) 1.45
Impairment of tetanus-specific cellular and humoral responses following tetanus vaccination in human lymphatic filariasis. Infect Immun (2004) 1.43
Human type 1 and 17 responses in latent tuberculosis are modulated by coincident filarial infection through cytotoxic T lymphocyte antigen-4 and programmed death-1. J Infect Dis (2009) 1.43
Longitudinal monitoring of the development of antifilarial antibodies and acquisition of Wuchereria bancrofti in a highly endemic area of Haiti. PLoS Negl Trop Dis (2012) 1.42
At homeostasis filarial infections have expanded adaptive T regulatory but not classical Th2 cells. J Immunol (2010) 1.42
Bacterial endosymbionts of Onchocerca volvulus in the pathogenesis of posttreatment reactions. J Infect Dis (2002) 1.36
An Epidemiologic Investigation of Potential Risk Factors for Nodding Syndrome in Kitgum District, Uganda. PLoS One (2013) 1.36
Expansion of pathogen-specific T-helper 1 and T-helper 17 cells in pulmonary tuberculosis with coincident type 2 diabetes mellitus. J Infect Dis (2013) 1.36
KIT D816V-associated systemic mastocytosis with eosinophilia and FIP1L1/PDGFRA-associated chronic eosinophilic leukemia are distinct entities. J Allergy Clin Immunol (2007) 1.33
Parasite antigen-driven basophils are a major source of IL-4 in human filarial infections. J Immunol (2004) 1.32
Diminished expression and function of TLR in lymphatic filariasis: a novel mechanism of immune dysregulation. J Immunol (2005) 1.31
Filarial lymphedema is characterized by antigen-specific Th1 and th17 proinflammatory responses and a lack of regulatory T cells. PLoS Negl Trop Dis (2009) 1.30
Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites. Blood (2008) 1.27
Rapid molecular assays for specific detection and quantitation of Loa loa microfilaremia. PLoS Negl Trop Dis (2011) 1.26
Filariasis in travelers presenting to the GeoSentinel Surveillance Network. PLoS Negl Trop Dis (2007) 1.26
Retention or inversion in stereospecific nickel-catalyzed cross-coupling of benzylic carbamates with arylboronic esters: control of absolute stereochemistry with an achiral catalyst. J Am Chem Soc (2013) 1.26
Novel phage display-based subtractive screening to identify vaccine candidates of Brugia malayi. Infect Immun (2004) 1.24
S100A8/A9 proteins mediate neutrophilic inflammation and lung pathology during tuberculosis. Am J Respir Crit Care Med (2013) 1.23
Identification of Wb123 as an early and specific marker of Wuchereria bancrofti infection. PLoS Negl Trop Dis (2012) 1.23
Safety and efficacy of the monoclonal anti-interleukin-5 antibody SCH55700 in the treatment of patients with hypereosinophilic syndrome. Blood (2003) 1.21
Lymphatics in human lymphatic filariasis: in vitro models of parasite-induced lymphatic remodeling. Lymphat Res Biol (2009) 1.21
Patent filarial infection modulates malaria-specific type 1 cytokine responses in an IL-10-dependent manner in a filaria/malaria-coinfected population. J Immunol (2009) 1.21
Class and subclass selection in parasite-specific antibody responses. Trends Parasitol (2003) 1.21
Stage-specific proteomic expression patterns of the human filarial parasite Brugia malayi and its endosymbiont Wolbachia. Proc Natl Acad Sci U S A (2011) 1.20
Comparative genomics of gene expression in the parasitic and free-living nematodes Strongyloides stercoralis and Caenorhabditis elegans. Genome Res (2004) 1.20
Immunopathogenesis of lymphatic filarial disease. Semin Immunopathol (2012) 1.19
Brugia malayi microfilariae induce cell death in human dendritic cells, inhibit their ability to make IL-12 and IL-10, and reduce their capacity to activate CD4+ T cells. J Immunol (2003) 1.19
A novel, multi-parallel, real-time polymerase chain reaction approach for eight gastrointestinal parasites provides improved diagnostic capabilities to resource-limited at-risk populations. Am J Trop Med Hyg (2013) 1.19
Filaria-induced monocyte dysfunction and its reversal following treatment. Infect Immun (2006) 1.16
Antibody to the filarial antigen Wb123 reflects reduced transmission and decreased exposure in children born following single mass drug administration (MDA). PLoS Negl Trop Dis (2012) 1.15
Molecular identification of Wolbachia from the filarial nematode Mansonella perstans. Mol Biochem Parasitol (2008) 1.15
Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface. J Immunol (2004) 1.14
Structural and immunologic cross-reactivity among filarial and mite tropomyosin: implications for the hygiene hypothesis. J Allergy Clin Immunol (2010) 1.14
Transient facial swellings in a patient with a remote African travel history. J Travel Med (2012) 1.13
Serum immunoglobulin G4 antibodies to the recombinant antigen, Ll-SXP-1, are highly specific for Loa loa infection. J Infect Dis (2002) 1.12
CTLA-4 in filarial infections: implications for a role in diminished T cell reactivity. J Immunol (2003) 1.10
Coincident filarial, intestinal helminth, and mycobacterial infection: helminths fail to influence tuberculin reactivity, but BCG influences hookworm prevalence. Am J Trop Med Hyg (2006) 1.08
Type 2 diabetes mellitus coincident with pulmonary tuberculosis is associated with heightened systemic type 1, type 17, and other proinflammatory cytokines. Ann Am Thorac Soc (2013) 1.08
Familial eosinophilia: a benign disorder? Blood (2004) 1.08
IgE memory: persistence of antigen-specific IgE responses years after treatment of human filarial infections. J Allergy Clin Immunol (2006) 1.07
Activation and regulation of toll-like receptors (TLRs) by helminth parasites. Immunol Res (2009) 1.07
Lymphangiogenesis and lymphatic remodeling induced by filarial parasites: implications for pathogenesis. PLoS Pathog (2009) 1.07
Proinflammatory cytokines dominate the early immune response to filarial parasites. J Immunol (2003) 1.07
Clinical characteristics of post-treatment reactions to ivermectin/albendazole for Wuchereria bancrofti in a region co-endemic for Mansonella perstans. Am J Trop Med Hyg (2003) 1.07
Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease. PLoS One (2013) 1.07
Filarial infection suppresses malaria-specific multifunctional Th1 and Th17 responses in malaria and filarial coinfections. J Immunol (2011) 1.07
Rapid Wuchereria bancrofti-specific antigen Wb123-based IgG4 immunoassays as tools for surveillance following mass drug administration programs on lymphatic filariasis. Clin Vaccine Immunol (2013) 1.06
Attenuation of toll-like receptor expression and function in latent tuberculosis by coexistent filarial infection with restoration following antifilarial chemotherapy. PLoS Negl Trop Dis (2009) 1.06
CD4(+) (and not CD25+) T cells are the predominant interleukin-10-producing cells in the circulation of filaria-infected patients. J Infect Dis (2008) 1.06
Acquisition of CD80 by human T cells at early stages of activation: functional involvement of CD80 acquisition in T cell to T cell interaction. J Immunol (2002) 1.05
Impact of filarial infections on coincident intracellular pathogens: Mycobacterium tuberculosis and Plasmodium falciparum. Curr Opin HIV AIDS (2012) 1.05
Rebound eosinophilia after treatment of hypereosinophilic syndrome and eosinophilic gastroenteritis with monoclonal anti-IL-5 antibody SCH55700. J Allergy Clin Immunol (2004) 1.05
Regulation of antigen-specific immunoglobulin G subclasses in response to conserved and polymorphic Plasmodium falciparum antigens in an in vitro model. Infect Immun (2002) 1.05
Filariasis attenuates anemia and proinflammatory responses associated with clinical malaria: a matched prospective study in children and young adults. PLoS Negl Trop Dis (2012) 1.04
Increased levels of both Th1 and Th2 cytokines in subjects with metabolic syndrome (CURES-103). Diabetes Technol Ther (2011) 1.04
Toward an understanding of the interaction between filarial parasites and host antigen-presenting cells. Immunol Rev (2004) 1.03
The complete mitochondrial genome sequence of the filarial nematode Wuchereria bancrofti from three geographic isolates provides evidence of complex demographic history. Mol Biochem Parasitol (2012) 1.03
Extended result reading window in lateral flow tests detecting exposure to Onchocerca volvulus: a new technology to improve epidemiological surveillance tools. PLoS One (2013) 1.02
Multilineage involvement of the fusion gene in patients with FIP1L1/PDGFRA-positive hypereosinophilic syndrome. Br J Haematol (2006) 1.02
Toward molecular parasitologic diagnosis: enhanced diagnostic sensitivity for filarial infections in mobile populations. J Clin Microbiol (2010) 1.01
Relapse following discontinuation of imatinib mesylate therapy for FIP1L1/PDGFRA-positive chronic eosinophilic leukemia: implications for optimal dosing. Blood (2007) 1.00
Filarial parasites induce NK cell activation, type 1 and type 2 cytokine secretion, and subsequent apoptotic cell death. J Immunol (2007) 0.99
Atopic phenotype is an important determinant of immunoglobulin E-mediated inflammation and expression of T helper cell type 2 cytokines to ascaris antigens in children exposed to ascariasis. J Infect Dis (2004) 0.99
Human immunoglobulin G mediates protective immunity and identifies protective antigens against larval Strongyloides stercoralis in mice. J Infect Dis (2004) 0.99
Basophils, basophilia and helminth infections. Chem Immunol Allergy (2006) 0.98
Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans. Infect Immun (2002) 0.98
Circulating biomarkers of pulmonary and extrapulmonary tuberculosis in children. Clin Vaccine Immunol (2013) 0.97