Published in Mol Gen Genet on July 25, 1978
An operator at -280 base pairs that is required for repression of araBAD operon promoter: addition of DNA helical turns between the operator and promoter cyclically hinders repression. Proc Natl Acad Sci U S A (1984) 5.42
Molecular cloning of TOL genes xylB and xylE in Escherichia coli. J Bacteriol (1981) 3.08
Plasmid vehicles for direct cloning of Escherichia coli promoters. J Bacteriol (1979) 2.87
Cloning, mapping and expression of the genetic determinant that encodes for the K88ab antigen. Nucleic Acids Res (1979) 2.80
Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313. Nucleic Acids Res (1979) 2.23
ClaI. a new restriction endonuclease from Caryophanon latum L. Nucleic Acids Res (1981) 2.21
Alterations in two conserved regions of promoter sequence lead to altered rates of polymerase binding and levels of gene expression. Nucleic Acids Res (1980) 1.57
Promoters selected from random DNA sequences. Proc Natl Acad Sci U S A (1986) 1.41
Genetic and physical analyses of Caulobacter crescentus trp genes. J Bacteriol (1984) 1.37
Molecular organization of heat-labile enterotoxin genes originating in Escherichia coli of human origin and construction of heat-labile toxoid-producing strains. J Bacteriol (1981) 1.19
New approach to tryptophan production by Escherichia coli: genetic manipulation of composite plasmids in vitro. Appl Environ Microbiol (1982) 1.02
Evidence for an internal promoter preceding tufA in the str operon of Escherichia coli. J Bacteriol (1982) 0.95
Bacteriophage lambda vehicle for the direct cloning of Escherichia coli promoter DNA sequences: feedback regulation of the rplJL-rpoBC operon. Proc Natl Acad Sci U S A (1980) 0.95
Position effect on expression of dsd genes cloned onto multicopy plasmids. J Bacteriol (1980) 0.91
A small cosmid for efficient cloning of large DNA fragments. Gene (1980) 22.61
Cosmids: a type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage lambda heads. Proc Natl Acad Sci U S A (1978) 16.33
5'-Terminal sequences of eucaryotic mRNA can be cloned with high efficiency. Nucleic Acids Res (1981) 8.10
Accelerated titration designs for phase I clinical trials in oncology. J Natl Cancer Inst (1997) 4.60
School-based programs to reduce sexual risk behaviors: a review of effectiveness. Public Health Rep (1994) 4.50
Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol (1996) 4.02
Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer? Lancet (2000) 3.79
Plasmids useable as gene-cloning vectors in an in vitro packaging by coliphage lambda: "cosmids". Gene (1978) 3.66
Characterization of mouse monoclonal antibodies specific for Friend murine leukemia virus-induced erythroleukemia cells: friend-specific and FMR-specific antigens. Virology (1981) 3.61
Cloning of the complete human cytomegalovirus genome in cosmids. Gene (1982) 3.55
Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience. Ann Oncol (2004) 3.29
Prognostic impact of amenorrhoea after adjuvant chemotherapy in premenopausal breast cancer patients with axillary node involvement: results of the International Breast Cancer Study Group (IBCSG) Trial VI. Eur J Cancer (1998) 3.03
Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. Nature (1987) 3.00
Gonadotrophin stimulation test ovarian function. Br Med J (1968) 2.99
Organization and function of an accident flying squad. Br Med J (1966) 2.88
Instability of palindromic DNA in Escherichia coli. Cold Spring Harb Symp Quant Biol (1981) 2.75
Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Ann Oncol (2006) 2.72
Plasmids controlling synthesis of hemolysin in Escherichia coli: molecular properties. J Bacteriol (1974) 2.71
Escherichia coli plasmids packageable in vitro in lambda bacteriophage particles. Methods Enzymol (1979) 2.71
Fertility and ageing. Hum Reprod Update (2005) 2.68
Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition. Pediatr Pulmonol (2001) 2.59
Analysis of calf-thymus satellite DNA: evidence for specific methylation of cytosine in C-G sequences. Eur J Biochem (1977) 2.47
Diabetes and tolerance in transgenic mice expressing class II MHC molecules in pancreatic beta cells. Cell (1988) 2.36
Sequence interruptions in enterobacterial repeated elements retain their ability to encode well-folded RNA secondary structures. Mol Microbiol (1997) 2.33
Free ribosomal DNA molecules from Tetrahymena pyriformis GL are giant palindromes. J Mol Biol (1976) 2.33
Precise and nearly-precise excision of the symmetrical inverted repeats of Tn5; common features of recA-independent deletion events in Escherichia coli. Gene (1983) 2.21
Molecular definition of the 22q11 deletions in velo-cardio-facial syndrome. Am J Hum Genet (1995) 2.19
Safer choices: reducing teen pregnancy, HIV, and STDs. Public Health Rep (2001) 2.07
Simplified northern blot hybridization using 5% sodium dodecyl sulfate. Biotechniques (1990) 2.07
Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency. Proc Natl Acad Sci U S A (1987) 1.98
A case of asthma. Br Med J (1976) 1.95
Interactions of heteroaromatic compounds with nucleic acids. A - T-specific non-intercalating DNA ligands. Eur J Biochem (1975) 1.93
Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: the International Breast Cancer Study Group Trial VII. J Clin Oncol (2000) 1.92
Identifying breast cancer patients at high risk for bone metastases. J Clin Oncol (2000) 1.91
Relationship between chromosome replication and F'lac episome replication in Escherichia coli. J Mol Biol (1973) 1.89
The nucleotide sequence of the murine I-E beta b immune response gene: evidence for gene conversion events in class II genes of the major histocompatibility complex. EMBO J (1984) 1.87
Gene shuttling: moving of cloned DNA into and out of eukaryotic cells. Nucleic Acids Res (1982) 1.85
Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. J Clin Oncol (2000) 1.81
Molecular biology of the H-2 histocompatibility complex. Science (1986) 1.81
Cloning of chicken lysozyme structural gene sequences synthesized in vitro. Nucleic Acids Res (1978) 1.80
Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Update (2006) 1.76
Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature. Neuroepidemiology (2013) 1.76
Gene cloning with small plasmids. Curr Top Microbiol Immunol (1977) 1.76
Risk factors for locoregional recurrence among breast cancer patients: results from International Breast Cancer Study Group Trials I through VII. J Clin Oncol (2003) 1.75
Cell-free synthesis of proteins coding for mobilisation functions of ColE1 and transposition functions of Tn3. Gene (1979) 1.74
Expression of Escherichia coli ribosomal protein and RNA polymerase genes cloned on plasmids. Mol Gen Genet (1979) 1.74
Induction of antigen-specific CD8+ T cells, T helper cells, and protective levels of antibody in humans by particle-mediated administration of a hepatitis B virus DNA vaccine. Vaccine (2000) 1.71
Towards less confusing terminology in reproductive medicine: a proposal. Hum Reprod (2004) 1.70
Response to mesna, doxorubicin, ifosfamide, and dacarbazine in 108 patients with metastatic or unresectable sarcoma and no prior chemotherapy. J Clin Oncol (1989) 1.69
Cloning a balanced translocation associated with DiGeorge syndrome and identification of a disrupted candidate gene. Nat Genet (1995) 1.68
Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design. Proc Natl Acad Sci U S A (1993) 1.67
Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update (2005) 1.66
Effect of systemic adjuvant treatment on first sites of breast cancer relapse. Lancet (1994) 1.64
Antenatal care of low risk obstetric patients by midwives. A randomised controlled trial. Med J Aust (1992) 1.60
Preliminary report on isolation of mycobacteria from patients with Crohn's disease. Dig Dis Sci (1989) 1.60
Arrangement of coding and intervening sequences of chicken lysozyme gene. Proc Natl Acad Sci U S A (1979) 1.53
Just-in-time coding of the problem list in a clinical environment. Proc AMIA Symp (1998) 1.52
A census of copies of the first edition of Andreas Vesalius' De humani corporis fabrica (1543), with a note on the recently discovered variant issue. J Hist Med Allied Sci (1984) 1.52
Progress in efforts to prevent the spread of HIV infection among youth. Public Health Rep (1992) 1.52
Influence of endocrine-related factors on response to perioperative chemotherapy for patients with node-negative breast cancer. J Clin Oncol (2001) 1.49
Characterization of DNA polymerase beta mRNA: cell-cycle and growth response in cultured human cells. Nucleic Acids Res (1988) 1.48
Transposition and insertion of intact, deleted and enlarged ampicillin transposon Tn3 from mini-R1 (Rsc) plasmids into transfer factors. Mol Gen Genet (1977) 1.48
Synthesis of ds-cDNA involving addition of dCMP tails to allow cloning of 5'-terminal m RNA sequences. Methods Enzymol (1983) 1.46
Routine tests during follow-up of patients after primary treatment for operable breast cancer. International (Ludwig) Breast Cancer Study Group (IBCSG) Ann Oncol (1995) 1.45
Hydroperoxide assay with the ferric-xylenol orange complex. Anal Biochem (1999) 1.45
The use of condoms with other contraceptive methods among young men and women. Fam Plann Perspect (1998) 1.44
Inducibility of human beta-interferon gene in mouse L-cell clones. Nature (1982) 1.43
A high-throughput system for segmenting nuclei using multiscale techniques. Cytometry A (2008) 1.42
The effect of adjuvant prednisone combined with CMF on patterns of relapse and occurrence of second malignancies in patients with breast cancer. International (Ludwig) Breast Cancer Study Group. Ann Oncol (1996) 1.41
Choroid plexus epithelium (normal and neoplastic) expresses synaptophysin. A potentially useful aid in differentiating carcinoma of the choroid plexus from metastatic papillary carcinomas. J Neuropathol Exp Neurol (1999) 1.40
Neurosis and marital interaction. I. Personality and symptoms. Br J Psychiatry (1970) 1.40
Neurosis and marital interaction. 3. Family roles and functions. Br J Psychiatry (1971) 1.39
Treatment of peritoneal dialysis related peritonitis--an Australian and New Zealand perspective. Aust N Z J Med (1999) 1.38
Serological comparison and haemagglutinating activity of Mycoplasma dispar. J Hyg (Lond) (1974) 1.36
Pseudo-Zellweger syndrome: deficiencies in several peroxisomal oxidative activities. J Pediatr (1986) 1.35
DNA immunization with minigenes: low frequency of memory cytotoxic T lymphocytes and inefficient antiviral protection are rectified by ubiquitination. J Virol (1998) 1.34
The structure of a thirty-six kilobase region of the human chromosome including the fibroblast interferon gene IFN-beta. Nucleic Acids Res (1981) 1.33
Possible role for COMT in psychosis associated with velo-cardio-facial syndrome. Lancet (1992) 1.31
CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc Natl Acad Sci U S A (1996) 1.31
A ribosomal RNA gene, rrnC, of Escherichia coli, mapped by specialized transducing lambdadilv and lambda drbs phages. Mol Gen Genet (1978) 1.31
Independence of F replication and chromosome replication in Escherichia coli. Mol Gen Genet (1975) 1.29
Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells. Biol Reprod (1990) 1.28
Motherhood improves learning and memory. Nature (1999) 1.28
Composite human VK genes and a model of their evolution. Nucleic Acids Res (1984) 1.27
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc Natl Acad Sci U S A (1996) 1.26
Kinetics, tissue specificity and pathological changes in murine rotavirus infection of mice. J Gen Virol (1986) 1.25
Cardiovascular disease and combined oral contraceptives: reviewing the evidence and balancing the risks. Hum Reprod Update (2000) 1.25
Experimental measles. II. Infection and immunity in the rhesus macaque. Virology (1997) 1.25
Large-scale screening of human sera with cytomegalovirus recombinant antigens. J Clin Microbiol (1990) 1.25
Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects. J Med Genet (2001) 1.24
A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11. Hum Mol Genet (1996) 1.23
The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family. Proc Natl Acad Sci U S A (1999) 1.23
Route and method of delivery of DNA vaccine influence immune responses in mice and non-human primates. Mol Med (1999) 1.22
Mycobacteria in Crohn's disease: DNA probes identify the wood pigeon strain of Mycobacterium avium and Mycobacterium paratuberculosis from human tissue. J Clin Microbiol (1992) 1.21
An electron microscopic investigation of time-related changes in the intestine of neonatal mice infected with murine rotavirus. J Pediatr Gastroenterol Nutr (1988) 1.21
A comparative study of metastatic renal cell carcinoma with correlation to subtype and primary tumor. Pathol Res Pract (2001) 1.19
Radiographic and CT findings of blunt chest trauma: aortic injuries and looking beyond them. Radiographics (1998) 1.19
Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection. J Immunol (2001) 1.19
Evidence that insect embryogenesis is regulated by ecdysteroids released from yolk proteins. Proc Natl Acad Sci U S A (1988) 1.19
Protective role of maternal antibodies against Haemophilus parasuis infection. Am J Vet Res (1999) 1.18