Instability of palindromic DNA in Escherichia coli.

Characterizing and measuring bias in sequence data. Genome Biol (2013) 4.39

Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis. Mol Cell Biol (1985) 4.14

Structural intermediates of deletion mutagenesis: a role for palindromic DNA. Proc Natl Acad Sci U S A (1984) 3.17

Construction of an infectious molecular clone of the autonomous parvovirus minute virus of mice. J Virol (1983) 2.95

Slow cruciform transitions in palindromic DNA. Proc Natl Acad Sci U S A (1983) 2.42

Structural organization and functional analysis of centromeric DNA in the fission yeast Schizosaccharomyces pombe. Mol Cell Biol (1988) 2.37

Construction of functional artificial minichromosomes in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci U S A (1989) 2.34

Inverted DNA repeats: a source of eukaryotic genomic instability. Mol Cell Biol (1993) 2.30

Replication slippage between distant short repeats in Saccharomyces cerevisiae depends on the direction of replication and the RAD50 and RAD52 genes. Mol Cell Biol (1995) 2.21

Palindrome resolution and recombination in the mammalian germ line. Mol Cell Biol (1997) 2.17

RNAi triggered by symmetrically transcribed transgenes in Drosophila melanogaster. Genetics (2002) 2.06

Isolation of telomerelike sequences from Cryptococcus neoformans and their use in high-efficiency transformation. Mol Cell Biol (1992) 1.97

A recB recC sbcB recJ host prevents recA-independent deletions in recombinant cosmid DNA propagated in Escherichia coli. J Bacteriol (1989) 1.90

Factors affecting inverted repeat stimulation of recombination and deletion in Saccharomyces cerevisiae. Genetics (1998) 1.78

Two operator sites separated by 599 base pairs are required for deoR repression of the deo operon of Escherichia coli. EMBO J (1985) 1.75

Seven-base-pair inverted repeats in DNA form stable hairpins in vivo in Saccharomyces cerevisiae. Genetics (1991) 1.73

Z-DNA-forming sequences generate large-scale deletions in mammalian cells. Proc Natl Acad Sci U S A (2006) 1.62

Electrotransformation and expression of bacterial genes encoding hygromycin phosphotransferase and beta-galactosidase in the pathogenic fungus Histoplasma capsulatum. Infect Immun (1998) 1.58

A 140-bp-long palindromic sequence induces double-strand breaks during meiosis in the yeast Saccharomyces cerevisiae. Genetics (1997) 1.57

On the deletion of inverted repeated DNA in Escherichia coli: effects of length, thermal stability, and cruciform formation in vivo. Genetics (1991) 1.56

Tissue-specific gene silencing mediated by a naturally occurring chalcone synthase gene cluster in Glycine max. Plant Cell (2004) 1.53

Illegitimate recombination at the replication origin of bacteriophage M13. Proc Natl Acad Sci U S A (1986) 1.50

The influence of primary and secondary DNA structure in deletion and duplication between direct repeats in Escherichia coli. Genetics (1993) 1.45

Mutations in POL1 increase the mitotic instability of tandem inverted repeats in Saccharomyces cerevisiae. Genetics (1993) 1.44

Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells. Mol Cell Biol (2002) 1.43

Structural perturbation in supercoiled DNA: hypersensitivity to modification by a single-strand-selective chemical reagent conferred by inverted repeat sequences. Nucleic Acids Res (1983) 1.41

Analysis of plasmid deletional instability in Bacillus subtilis. J Bacteriol (1985) 1.25

Autonomous replication of foreign DNA in Histoplasma capsulatum: role of native telomeric sequences. J Bacteriol (1993) 1.23

Long palindromic sequences induce double-strand breaks during meiosis in yeast. Mol Cell Biol (2000) 1.22

A new type of plasmid from a wild isolate of Dictyostelium species: the existence of closely situated long inverted repeats. Nucleic Acids Res (1987) 1.20

Comparison of physical and genetic properties of palindromic DNA sequences. J Bacteriol (1985) 1.17

Altered replication and inverted repeats induce mismatch repair-independent recombination between highly diverged DNAs in yeast. Mol Cell Biol (1997) 1.11

Long inverted repeats are an at-risk motif for recombination in mammalian cells. Genetics (1999) 1.07

Dynamics of cruciform extrusion in supercoiled DNA: use of a synthetic inverted repeat to study conformational populations. EMBO J (1983) 1.07

Unusual regulation of simian virus 40 early-region transcription in genomes containing two origins of DNA replication. Mol Cell Biol (1984) 1.05

Large palindromes in the lambda phage genome are preserved in a rec+ host by inhibiting lambda DNA replication. Proc Natl Acad Sci U S A (1987) 1.04

Relative orientation of RNA helices in a group 1 ribozyme determined by helix extension electron microscopy. EMBO J (1995) 1.03

Models for chromosomal replication-independent non-B DNA structure-induced genetic instability. Mol Carcinog (2009) 1.02

The effects of nucleotide sequence changes on DNA secondary structure formation in Escherichia coli are consistent with cruciform extrusion in vivo. Genetics (1994) 0.98

DNA polymerases ζ and Rev1 mediate error-prone bypass of non-B DNA structures. Nucleic Acids Res (2013) 0.93

Unusually long palindromes are abundant in mitochondrial control regions of insects and nematodes. PLoS One (2006) 0.85

The yin and yang of repair mechanisms in DNA structure-induced genetic instability. Mutat Res (2012) 0.82

Alu pair exclusions in the human genome. Mob DNA (2011) 0.80

Sequence organization and gene expression of pGD1, a plasmid found in a wild isolate of Dictyostelium. Nucleic Acids Res (1989) 0.80

The effects of central asymmetry on the propagation of palindromic DNA in bacteriophage lambda are consistent with cruciform extrusion in vivo. Genetics (1993) 0.80

Effects of palindromes on in vivo DNA replication and mutagenesis in bacteriophage phi X174 RF DNA. Nucleic Acids Res (1988) 0.77

DIR: a novel DNA rearrangement associated with inverted repeats. Nucleic Acids Res (1997) 0.77

Bidirectional Promoter Engineering for Single Cell MicroRNA Sensors in Embryonic Stem Cells. PLoS One (2016) 0.76

pBR322 vectors having tetracycline-dependent replication. Plasmid (2016) 0.75

Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes. PLoS One (2017) 0.75

A small cosmid for efficient cloning of large DNA fragments. Gene (1980) 22.61

Cosmids: a type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage lambda heads. Proc Natl Acad Sci U S A (1978) 16.33

Accelerated titration designs for phase I clinical trials in oncology. J Natl Cancer Inst (1997) 4.60

School-based programs to reduce sexual risk behaviors: a review of effectiveness. Public Health Rep (1994) 4.50

Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol (1996) 4.02

Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer? Lancet (2000) 3.79

Plasmids useable as gene-cloning vectors in an in vitro packaging by coliphage lambda: "cosmids". Gene (1978) 3.66

Characterization of mouse monoclonal antibodies specific for Friend murine leukemia virus-induced erythroleukemia cells: friend-specific and FMR-specific antigens. Virology (1981) 3.61

Cloning of the complete human cytomegalovirus genome in cosmids. Gene (1982) 3.55

Body mass index as a prognostic feature in operable breast cancer: the International Breast Cancer Study Group experience. Ann Oncol (2004) 3.29

Prognostic impact of amenorrhoea after adjuvant chemotherapy in premenopausal breast cancer patients with axillary node involvement: results of the International Breast Cancer Study Group (IBCSG) Trial VI. Eur J Cancer (1998) 3.03

Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans. Nature (1987) 3.00

Gonadotrophin stimulation test ovarian function. Br Med J (1968) 2.99

Organization and function of an accident flying squad. Br Med J (1966) 2.88

Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Ann Oncol (2006) 2.72

Escherichia coli plasmids packageable in vitro in lambda bacteriophage particles. Methods Enzymol (1979) 2.71

Fertility and ageing. Hum Reprod Update (2005) 2.68

Acceleration of lung disease in children with cystic fibrosis after Pseudomonas aeruginosa acquisition. Pediatr Pulmonol (2001) 2.59

Sequence interruptions in enterobacterial repeated elements retain their ability to encode well-folded RNA secondary structures. Mol Microbiol (1997) 2.33

Free ribosomal DNA molecules from Tetrahymena pyriformis GL are giant palindromes. J Mol Biol (1976) 2.33

Precise and nearly-precise excision of the symmetrical inverted repeats of Tn5; common features of recA-independent deletion events in Escherichia coli. Gene (1983) 2.21

Molecular definition of the 22q11 deletions in velo-cardio-facial syndrome. Am J Hum Genet (1995) 2.19

Safer choices: reducing teen pregnancy, HIV, and STDs. Public Health Rep (2001) 2.07

Human peroxisomal 3-oxoacyl-coenzyme A thiolase deficiency. Proc Natl Acad Sci U S A (1987) 1.98

A case of asthma. Br Med J (1976) 1.95

Burdens and benefits of adjuvant cyclophosphamide, methotrexate, and fluorouracil and tamoxifen for elderly patients with breast cancer: the International Breast Cancer Study Group Trial VII. J Clin Oncol (2000) 1.92

Identifying breast cancer patients at high risk for bone metastases. J Clin Oncol (2000) 1.91

Relationship between chromosome replication and F'lac episome replication in Escherichia coli. J Mol Biol (1973) 1.89

Early start of adjuvant chemotherapy may improve treatment outcome for premenopausal breast cancer patients with tumors not expressing estrogen receptors. The International Breast Cancer Study Group. J Clin Oncol (2000) 1.81

The expression of tetracycline resistance after insertion of foreign DNA fragments between the EcoRI and HindIII sites of the plasmid cloning vector pBR 322. Mol Gen Genet (1978) 1.77

Among patients treated for IVF with gonadotrophins and GnRH analogues, is the probability of live birth dependent on the type of analogue used? A systematic review and meta-analysis. Hum Reprod Update (2006) 1.76

Global epidemiology of amyotrophic lateral sclerosis: a systematic review of the published literature. Neuroepidemiology (2013) 1.76

Gene cloning with small plasmids. Curr Top Microbiol Immunol (1977) 1.76

Risk factors for locoregional recurrence among breast cancer patients: results from International Breast Cancer Study Group Trials I through VII. J Clin Oncol (2003) 1.75

Cell-free synthesis of proteins coding for mobilisation functions of ColE1 and transposition functions of Tn3. Gene (1979) 1.74

Expression of Escherichia coli ribosomal protein and RNA polymerase genes cloned on plasmids. Mol Gen Genet (1979) 1.74

Towards less confusing terminology in reproductive medicine: a proposal. Hum Reprod (2004) 1.70

Response to mesna, doxorubicin, ifosfamide, and dacarbazine in 108 patients with metastatic or unresectable sarcoma and no prior chemotherapy. J Clin Oncol (1989) 1.69

Cloning a balanced translocation associated with DiGeorge syndrome and identification of a disrupted candidate gene. Nat Genet (1995) 1.68

Crystal structures of native and inhibited forms of human cathepsin D: implications for lysosomal targeting and drug design. Proc Natl Acad Sci U S A (1993) 1.67

Are endogenous LH levels during ovarian stimulation for IVF using GnRH analogues associated with the probability of ongoing pregnancy? A systematic review. Hum Reprod Update (2005) 1.66

Effect of systemic adjuvant treatment on first sites of breast cancer relapse. Lancet (1994) 1.64

Antenatal care of low risk obstetric patients by midwives. A randomised controlled trial. Med J Aust (1992) 1.60

Preliminary report on isolation of mycobacteria from patients with Crohn's disease. Dig Dis Sci (1989) 1.60

Progress in efforts to prevent the spread of HIV infection among youth. Public Health Rep (1992) 1.52

Just-in-time coding of the problem list in a clinical environment. Proc AMIA Symp (1998) 1.52

A census of copies of the first edition of Andreas Vesalius' De humani corporis fabrica (1543), with a note on the recently discovered variant issue. J Hist Med Allied Sci (1984) 1.52

Influence of endocrine-related factors on response to perioperative chemotherapy for patients with node-negative breast cancer. J Clin Oncol (2001) 1.49

Characterization of DNA polymerase beta mRNA: cell-cycle and growth response in cultured human cells. Nucleic Acids Res (1988) 1.48

Routine tests during follow-up of patients after primary treatment for operable breast cancer. International (Ludwig) Breast Cancer Study Group (IBCSG) Ann Oncol (1995) 1.45

Hydroperoxide assay with the ferric-xylenol orange complex. Anal Biochem (1999) 1.45

The use of condoms with other contraceptive methods among young men and women. Fam Plann Perspect (1998) 1.44

Inducibility of human beta-interferon gene in mouse L-cell clones. Nature (1982) 1.43

A high-throughput system for segmenting nuclei using multiscale techniques. Cytometry A (2008) 1.42

The effect of adjuvant prednisone combined with CMF on patterns of relapse and occurrence of second malignancies in patients with breast cancer. International (Ludwig) Breast Cancer Study Group. Ann Oncol (1996) 1.41

Choroid plexus epithelium (normal and neoplastic) expresses synaptophysin. A potentially useful aid in differentiating carcinoma of the choroid plexus from metastatic papillary carcinomas. J Neuropathol Exp Neurol (1999) 1.40

Neurosis and marital interaction. I. Personality and symptoms. Br J Psychiatry (1970) 1.40

Neurosis and marital interaction. 3. Family roles and functions. Br J Psychiatry (1971) 1.39

Treatment of peritoneal dialysis related peritonitis--an Australian and New Zealand perspective. Aust N Z J Med (1999) 1.38

Serological comparison and haemagglutinating activity of Mycoplasma dispar. J Hyg (Lond) (1974) 1.36

Pseudo-Zellweger syndrome: deficiencies in several peroxisomal oxidative activities. J Pediatr (1986) 1.35

The structure of a thirty-six kilobase region of the human chromosome including the fibroblast interferon gene IFN-beta. Nucleic Acids Res (1981) 1.33

Possible role for COMT in psychosis associated with velo-cardio-facial syndrome. Lancet (1992) 1.31

A ribosomal RNA gene, rrnC, of Escherichia coli, mapped by specialized transducing lambdadilv and lambda drbs phages. Mol Gen Genet (1978) 1.31

CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc Natl Acad Sci U S A (1996) 1.31

Independence of F replication and chromosome replication in Escherichia coli. Mol Gen Genet (1975) 1.29

Motherhood improves learning and memory. Nature (1999) 1.28

Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum. Proc Natl Acad Sci U S A (1996) 1.26

Kinetics, tissue specificity and pathological changes in murine rotavirus infection of mice. J Gen Virol (1986) 1.25

Cardiovascular disease and combined oral contraceptives: reviewing the evidence and balancing the risks. Hum Reprod Update (2000) 1.25

Experimental measles. II. Infection and immunity in the rhesus macaque. Virology (1997) 1.25

Mutation analysis of TBX1 in non-deleted patients with features of DGS/VCFS or isolated cardiovascular defects. J Med Genet (2001) 1.24

A transcription map of the DiGeorge and velo-cardio-facial syndrome minimal critical region on 22q11. Hum Mol Genet (1996) 1.23

The human LARGE gene from 22q12.3-q13.1 is a new, distinct member of the glycosyltransferase gene family. Proc Natl Acad Sci U S A (1999) 1.23

Mycobacteria in Crohn's disease: DNA probes identify the wood pigeon strain of Mycobacterium avium and Mycobacterium paratuberculosis from human tissue. J Clin Microbiol (1992) 1.21

An electron microscopic investigation of time-related changes in the intestine of neonatal mice infected with murine rotavirus. J Pediatr Gastroenterol Nutr (1988) 1.21

A comparative study of metastatic renal cell carcinoma with correlation to subtype and primary tumor. Pathol Res Pract (2001) 1.19

Radiographic and CT findings of blunt chest trauma: aortic injuries and looking beyond them. Radiographics (1998) 1.19

Mice lacking the chemokine receptor CCR1 show increased susceptibility to Toxoplasma gondii infection. J Immunol (2001) 1.19

Evidence that insect embryogenesis is regulated by ecdysteroids released from yolk proteins. Proc Natl Acad Sci U S A (1988) 1.19

Protective role of maternal antibodies against Haemophilus parasuis infection. Am J Vet Res (1999) 1.18

Duration of adjuvant chemotherapy for breast cancer: a joint analysis of two randomised trials investigating three versus six courses of CMF. Br J Cancer (2002) 1.17

Peroxisomal defects in neonatal-onset and X-linked adrenoleukodystrophies. Science (1985) 1.15

Cloning, sequencing and expression in Escherichia coli of the D-2-hydroxyisocaproate dehydrogenase gene of Lactobacillus casei. Gene (1989) 1.14

Bronchoalveolar lavage for the preparation of free lung cells: technique and complications. Br J Dis Chest (1980) 1.14

Respiratory failure in shock. Ann Surg (1969) 1.14

Siblings, multiple births, and the incidence of allergic disease: a birth cohort study using the West Midlands general practice research database. Thorax (2001) 1.13

Wisconsin cystic fibrosis chest radiograph scoring system: validation and standardization for application to longitudinal studies. Pediatr Pulmonol (2000) 1.12

Diabetes mellitus in an urbanized, isolated Polynesian population. The Funafuti survey. Diabetes (1977) 1.12

On the structure of the deo operon of Escherichia coli. Mol Gen Genet (1977) 1.11

The use of imaging in the early development of neuropharmacological drugs: a survey of approved NDAs. Clin Pharmacol Ther (2007) 1.11

Interaction of Mycoplasma dispar and Mycoplasma agalactiae subsp. bovis with bovine alveolar macrophages and bovine lacteal polymorphonuclear leukocytes. Infect Immun (1976) 1.11

A study of caloric restriction and cardiovascular aging in cynomolgus monkeys (Macaca fascicularis): a potential model for aging research. J Gerontol A Biol Sci Med Sci (1997) 1.09

A rapid heat-resistant technique for presumptive identification of Salmonella on desoxycholate-citrate agar. Eur J Clin Microbiol Infect Dis (1992) 1.08

Severe transient hemiplegia after general anaesthesia for prostatectomy. Br J Anaesth (2009) 1.07

Examination of genetic linkage of chromosome 15 to schizophrenia in a large Veterans Affairs Cooperative Study sample. Am J Med Genet (2001) 1.07

Responsiveness of a single-item indicator versus a multi-item scale: assessment of emotional well-being in an international adjuvant breast cancer trial. Med Care (1996) 1.07

Pulmonary mucosa-associated lymphoid tissue lymphoma: CT and pathologic findings. AJR Am J Roentgenol (1999) 1.06

Insulin-like growth factor-1 inscribes a gene expression profile for angiogenic factors and cancer progression in breast epithelial cells. Neoplasia (2002) 1.04

Altered colonic function and microbiota profile in a mouse model of chronic depression. Neurogastroenterol Motil (2013) 1.04