Published in Biochem Pharmacol on April 15, 1987
Analysis of the relationship between the blood concentration of several metals, macro- and micronutrients and endocrine disorders associated with male aging. Environ Geochem Health (2015) 0.76
Protection of cadmium chloride induced DNA damage by Lamiaceae plants. Asian Pac J Trop Biomed (2011) 0.75
Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. FASEB J (2001) 2.55
Cobalt induction of hepatic heme oxygenase; with evidence that cytochrome P-450 is not essential for this enzyme activity. Proc Natl Acad Sci U S A (1974) 2.41
Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible. J Biol Chem (1986) 2.36
Isolation and characterization of a cDNA from the rat brain that encodes hemoprotein heme oxygenase-3. Eur J Biochem (1997) 2.16
Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450. J Biol Chem (1975) 2.05
Aberrant methylation of donor genome in cloned bovine embryos. Nat Genet (2001) 1.94
Human heme oxygenase-2: characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal. Arch Biochem Biophys (1992) 1.87
Metals as regulators of heme metabolism. Science (1977) 1.86
Studies on the mechanism of induction of haem oxygenase by cobalt and other metal ions. Biochem J (1976) 1.84
Anticipation and instability of IT-15 (CAG)n repeats in parent-offspring pairs with Huntington disease. Am J Hum Genet (1995) 1.84
Purification and characterization of biliverdin reductase from rat liver. J Biol Chem (1981) 1.63
Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice. J Neurochem (1999) 1.55
Heme oxygenase-2 is a hemoprotein and binds heme through heme regulatory motifs that are not involved in heme catalysis. J Biol Chem (1997) 1.44
Neurons overexpressing heme oxygenase-1 resist oxidative stress-mediated cell death. J Neurochem (2000) 1.42
Zinc . protoporphyrin is a selective inhibitor of heme oxygenase activity in the neonatal rat. Biochim Biophys Acta (1981) 1.42
Rapid induction of heme oxygenase 1 mRNA and protein by hyperthermia in rat brain: heme oxygenase 2 is not a heat shock protein. Proc Natl Acad Sci U S A (1991) 1.39
Purification and characterization of the major constitutive form of testicular heme oxygenase. The noninducible isoform. J Biol Chem (1986) 1.36
Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015). Nat Med (2000) 1.31
Evidence suggesting that the two forms of heme oxygenase are products of different genes. J Biol Chem (1988) 1.29
Tin: a potent inducer of heme oxygenase in kidney. Science (1976) 1.27
Characterization of two heme oxygenase isoforms in rat spleen: comparison with the hematin-induced and constitutive isoforms of the liver. Biochem Biophys Res Commun (1986) 1.26
Inhibitory effect of selenite on invasion of HT1080 tumor cells. J Biol Chem (2001) 1.25
Regulation of photomorphogenesis by expression of mammalian biliverdin reductase in transgenic Arabidopsis plants. Plant Cell (1997) 1.23
Heme oxygenase 2 is present in interstitial cell networks of the mouse small intestine. Gastroenterology (1998) 1.20
Solubilization and partial purification of heme oxygenase from rat liver. J Biol Chem (1977) 1.19
Prematurely evoked synthesis and induction of delta-aminolevulinate synthetase in neonatal liver. Evidence for metal ion repression of enzyme formation. J Biol Chem (1978) 1.19
Developmental expression of heme oxygenase isozymes in rat brain. Two HO-2 mRNAs are detected. J Biol Chem (1990) 1.19
Cobalt inhibition of synthesis and induction of delta-aminolevulinate synthase in liver. Proc Natl Acad Sci U S A (1976) 1.18
Regulation of heme pathway enzymes and cellular glutathione content by metals that do not chelate with tetrapyrroles: blockade of metal effects by thiols. Proc Natl Acad Sci U S A (1977) 1.18
Cobalt regulation of heme synthesis and degradation in avian embryo liver cell culture. J Biol Chem (1977) 1.18
Type D retrovirus Gag polyprotein interacts with the cytosolic chaperonin TRiC. J Virol (2001) 1.14
Study of the developmental pattern of heme catabolism in liver and the effects of cobalt on cytochrome P-450 and the rate of heme oxidation during the neonatal period. J Exp Med (1975) 1.12
Isolation, characterization, and expression in Escherichia coli of a cDNA encoding rat heme oxygenase-2. J Biol Chem (1990) 1.12
The induction of heme oxidation in various tissues by trace metals: evidence for the catabolism of endogenous heme by hepatic heme oxygenase. Ann Clin Res (1976) 1.11
Resolution of the rat brain heme oxygenase activity: absence of a detectable amount of the inducible form (HO-1). Arch Biochem Biophys (1988) 1.11
Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain. J Neurochem (1993) 1.10
The degradative effects of porphyrins and heme compounds on components of the microsomal mixed function oxidase system. J Biol Chem (1975) 1.10
Human biliverdin reductase is autophosphorylated, and phosphorylation is required for bilirubin formation. J Biol Chem (2001) 1.08
Normal and heat-induced patterns of expression of heme oxygenase-1 (HSP32) in rat brain: hyperthermia causes rapid induction of mRNA and protein. J Neurochem (1992) 1.05
Inactivation of phytochrome- and phycobiliprotein-chromophore precursors by rat liver biliverdin reductase. J Biol Chem (1993) 1.05
Induction of heart heme oxygenase-1 (HSP32) by hyperthermia: possible role in stress-mediated elevation of cyclic 3':5'-guanosine monophosphate. J Pharmacol Exp Ther (1994) 1.04
Effects of reactive oxygen species on proliferation of Chinese hamster lung fibroblast (V79) cells. Free Radic Biol Med (2001) 1.03
Studies on heme transfer from microsomal hemoproteins to heme-binding plasma proteins. Mol Pharmacol (1974) 1.03
Interaction of heme oxygenase-2 with nitric oxide donors. Is the oxygenase an intracellular 'sink' for NO? Eur J Biochem (1999) 1.02
Selective vulnerability of glutathione metabolism and cellular defense mechanisms in rat striatum to manganese. J Pharmacol Exp Ther (1988) 1.01
Efficient integration of short interspersed element-flanked foreign DNA via homologous recombination. J Biol Chem (1999) 1.01
Distribution of constitutive (HO-2) and heat-inducible (HO-1) heme oxygenase isozymes in rat testes: HO-2 displays stage-specific expression in germ cells. Endocrinology (1995) 1.00
Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. Am J Physiol (1998) 0.98
Se-methylselenocysteine induces apoptosis mediated by reactive oxygen species in HL-60 cells. Free Radic Biol Med (2001) 0.97
New developments in the regulation of heme metabolism and their implications. Crit Rev Toxicol (1984) 0.96
Enzymatic oxidation of cobalt protoporphyrin IX: observations on the mechanism of heme oxygenase action. Biochemistry (1977) 0.96
A novel system for providing compatible blood to patients during surgery: "self-service" electronic blood banking by nursing staff. Transfusion (1996) 0.95
In situ hybridization and immunohistochemical localization of heme oxygenase-2 mRNA and protein in normal rat brain: Differential distribution of isozyme 1 and 2. Mol Cell Neurosci (1992) 0.94
Heme oxygenase-2 interaction with metalloporphyrins: function of heme regulatory motifs. Antioxid Redox Signal (2001) 0.94
Multiplicity of heme oxygenase isozymes. HO-1 and HO-2 are different molecular species in rat and rabbit. J Biol Chem (1989) 0.94
Nitric oxide induces heme oxygenase-1 via mitogen-activated protein kinases ERK and p38. Cell Mol Biol (Noisy-le-grand) (2000) 0.94
Characterization of a cDNA-encoding rabbit brain heme oxygenase-2 and identification of a conserved domain among mammalian heme oxygenase isozymes: possible heme-binding site? Arch Biochem Biophys (1991) 0.93
Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons. Neuroscience (1994) 0.93
Histochemical localization of heme oxygenase-2 protein and mRNA expression in rat brain. Brain Res Brain Res Protoc (1997) 0.92
Enzymes of heme metabolism in the kidney: regulation by trace metals which do not form heme complexes. J Exp Med (1977) 0.92
Regulation of heme oxygenase-2 by glucocorticoids in neonatal rat brain: characterization of a functional glucocorticoid response element. Biochim Biophys Acta (1997) 0.91
Expression and characterization of a cDNA for rat kidney biliverdin reductase. Evidence suggesting the liver and kidney enzymes are the same transcript product. J Biol Chem (1992) 0.91
Se-methylselenocysteine induces apoptosis through caspase activation in HL-60 cells. Carcinogenesis (2001) 0.91
Inhibition of the enzymes of glutathione metabolism by mercuric chloride in the rat kidney: reversal by selenium. Biochem Pharmacol (1982) 0.90
The structure, organization and differential expression of the gene encoding rat heme oxygenase-2. Gene (1994) 0.90
Oxidation of heme c derivatives by purified heme oxygenase. Evidence for the presence of one molecular species of heme oxygenase in the rat liver. J Biol Chem (1982) 0.89
Permanent focal and transient global cerebral ischemia increase glial and neuronal expression of heme oxygenase-1, but not heme oxygenase-2, protein in rat brain. Neurosci Lett (1996) 0.89
Enhanced neuronal expression of the oxidoreductase--biliverdin reductase--after permanent focal cerebral ischemia. Brain Res (1999) 0.89
The functioning of individuals on a drug abuse treatment waiting list. Am J Drug Alcohol Abuse (1989) 0.88
Effect of bioflavonoids extracted from the bark of Pinus maritima on proinflammatory cytokine interleukin-1 production in lipopolysaccharide-stimulated RAW 264.7. Toxicol Appl Pharmacol (2000) 0.87
Rat liver cytochrome P-450b, P-420b, and P-420c are degraded to biliverdin by heme oxygenase. Arch Biochem Biophys (1988) 0.87
Enhancement of heme oxygenase-1 synthesis by glutathione depletion in Chinese hamster ovary cells. Arch Biochem Biophys (1991) 0.87
Biliverdin reductase is heat resistant and coexpressed with constitutive and heat shock forms of heme oxygenase in brain. J Neurochem (1993) 0.87
Renal ischemia/reperfusion up-regulates heme oxygenase-1 (HSP32) expression and increases cGMP in rat heart. J Pharmacol Exp Ther (1996) 0.87
Corticosterone regulates heme oxygenase-2 and NO synthase transcription and protein expression in rat brain. J Neurochem (1994) 0.87
Regional distribution of the enzymes of haem biosynthesis and the inhibition of 5-aminolaevulinate synthase by manganese in the rat brain. Biochem J (1980) 0.86
Inhibition of testicular cytochrome P-450-dependent steroid biosynthesis by cis-platinum. Reversal by human chorionic gonadotropin. J Biol Chem (1985) 0.85
Regulation and expression of heme oxygenase enzymes in aged-rat brain: age related depression in HO-1 and HO-2 expression and altered stress-response. J Neural Transm (Vienna) (2006) 0.85
Hepatic heme metabolism: possible role of biliverdin in the regulation of heme oxygenase activity. Biochem Biophys Res Commun (1984) 0.85
Detection of 10 variants of biliverdin reductase in rat liver by two-dimensional gel electrophoresis. J Biol Chem (1989) 0.85
Characterization of glutathione S-transferases in rat kidney. Alteration of composition by cis-platinum. Biochem J (1988) 0.85
Phenylhydrazine-mediated induction of haem oxygenase activity in rat liver and kidney and development of hyperbilirubinaemia. Inhibition by zinc-protoporphyrin. Biochem J (1984) 0.85
Site of injury-directed induction of heme oxygenase-1 and -2 in experimental spinal cord injury: differential functions in neuronal defense mechanisms? J Neurochem (2001) 0.85
Role of trace metals in regulation of cellular heme and hemoprotein metabolism: sensitizing effects of chronic iron treatment on acute gold toxicity. Drug Metab Rev (1979) 0.85
Tin-protoporphyrin-mediated disruption in vivo of heme oxygenase-2 protein integrity and activity in rat brain. Pediatr Res (1992) 0.84
Inhibition mechanisms of bioflavonoids extracted from the bark of Pinus maritima on the expression of proinflammatory cytokines. Ann N Y Acad Sci (2001) 0.84
Comparative effects of tin- and zinc-protoporphyrin on steroidogenesis: tin-protoporphyrin is a potent inhibitor of cytochrome P-450-dependent activities in the rat adrenals. Pediatr Res (1992) 0.83
Characterization of an NADH-dependent haem-degrading system in ox heart mitochondria. Biochem J (1987) 0.82
Influence of oral administration of estradiol-17β and testosterone on growth, digestion, food conversion and metabolism in the underyearling red sea bream, Chrysophrys major. Fish Physiol Biochem (1993) 0.82
Regulation of cytochrome P-450-dependent microsomal drug-metabolizing enzymes by nickel, cobalt, and iron. Clin Pharmacol Ther (1977) 0.82
Coordinated expression and mechanism of induction of HSP32 (heme oxygenase-1) mRNA by hyperthermia in rat organs. Biochim Biophys Acta (1994) 0.82
Interaction of Fe-protoporphyrin IX and heme analogues with purified recombinant heme oxygenase-2, the constitutive isozyme of the brain and testes. J Biol Chem (1994) 0.81
Inhibitory effects of chlorophyllin on 7,12-dimethylbenz[a]anthracene-induced bacterial mutagenesis and mouse skin carcinogenesis. Cancer Lett (1999) 0.81
Reconstitution of carbon monoxide-binding particles after removal of heme by serum albumin. Mol Pharmacol (1973) 0.81
Prevention of neonatal hyperbilirubinaemia in non-human primates by Zn-protoporphyrin. Biochem J (1985) 0.80
Enhancement and inhibition of enzymes of heme metabolism by diethyl maleate in the rat kidney. Arch Biochem Biophys (1982) 0.80
Characterization of the heme of cytochrome P-450 using gas chromatography-mass spectrometry. Arch Biochem Biophys (1973) 0.80
Evidence for the catabolism of polychlorinated biphenyl-induced cytochrome P-448 by microsomal heme oxygenase, and the inhibition of delta-aminolevulinate dehydratase by polychlorinated biphenyls. J Exp Med (1976) 0.80