PubRank

P J Fialkow

Author PubWeight™ 146.78‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Polycythemia vera: stem-cell and probable clonal origin of the disease. N Engl J Med 1976 3.18
2 Clonal origin of human tumors. Biochim Biophys Acta 1976 3.07
3 Chronic myelocytic leukemia: clonal origin in a stem cell common to the granulocyte, erythrocyte, platelet and monocyte/macrophage. Am J Med 1977 2.82
4 Direct evidence for the presence of Epstein-Barr virus DNA and nuclear antigen in malignant epithelial cells from patients with poorly differentiated carcinoma of the nasopharynx. Proc Natl Acad Sci U S A 1974 2.66
5 Human tumors studied with genetic markers. Birth Defects Orig Artic Ser 1976 2.52
6 Clonal origin of chronic myelocytic leukemia in man. Proc Natl Acad Sci U S A 1967 2.48
7 Primordial cell pool size and lineage relationships of five human cell types. Ann Hum Genet 1973 2.21
8 Agnogenic myeloid metaplasia: a clonal proliferation of hematopoietic stem cells with secondary myelofibrosis. Blood 1978 1.83
9 Growth and antigenic properties of a biopsy-derived Burkitt's lymphoma in thymus-less (nude) mice. Int J Cancer 1973 1.80
10 Expression of the gene defect in X-linked agammaglobulinemia. N Engl J Med 1986 1.80
11 Leukaemic transformation of engrafted human marrow cells in vivo. Lancet 1971 1.79
12 The origin and development of human tumors studied with cell markers. N Engl J Med 1974 1.73
13 "Immunologic" oncogenesis. Blood 1967 1.61
14 Chronic myelocytic leukemia. Origin of some lymphocytes from leukemic stem cells. J Clin Invest 1978 1.55
15 Polycythemia vera. The in vitro response of normal and abnormal stem cell lines to erythropoietin. J Clin Invest 1978 1.53
16 Use of genetic markers to study cellular origin and development of tumors in human females. Adv Cancer Res 1972 1.46
17 Immunoglobulin and glucose-6-phosphate dehydrogenase as markers of cellular origin in Burkitt lymphoma. J Exp Med 1973 1.42
18 Liver cysts in patients with autosomal dominant polycystic kidney disease. Am J Med 1980 1.41
19 Autoimmunity and chromosomal aberrations. Am J Hum Genet 1966 1.41
20 Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell. Blood 1981 1.40
21 Evidence for a multistep pathogenesis of chronic myelogenous leukemia. Blood 1981 1.39
22 The pathogenesis of myeloproliferative syndromes. Br J Haematol 1978 1.39
23 Evidence for a multistep pathogenesis of a myelodysplastic syndrome. Blood 1984 1.38
24 Donor origin of the in vitro haematopoietic microenvironment after marrow transplantation in man. Nature 1982 1.35
25 Clonal development, stem-cell differentiation, and clinical remissions in acute nonlymphocytic leukemia. N Engl J Med 1987 1.32
26 Lack of association between cirrhosis and the common types of color blindness. N Engl J Med 1966 1.29
27 Clonal origin for individual Burkitt tumours. Lancet 1970 1.27
28 Acute nonlymphocytic leukemia: heterogeneity of stem cell origin. Blood 1981 1.26
29 Clonal origin of human tumors. Annu Rev Med 1979 1.25
30 Autoimmunity in chronic graft-versus-host disease. Clin Exp Immunol 1973 1.23
31 Lymphocyte abnormalities in Behçet's syndrome. Clin Exp Immunol 1980 1.20
32 Foreign-cell contamination in Burkitt tumours. Lancet 1971 1.16
33 X-chromosome inactivation and the Xg locus. Am J Hum Genet 1970 1.15
34 Increased frequency of thyroid autoantibodies in mothers of patients with Down's syndrome. Lancet 1965 1.14
35 Mental retardation in methemoglobinemia due to diaphorase deficiency. N Engl J Med 1965 1.13
36 Fine structure alterations of elastic fibers in pseudoxanthoma elasticum. Clin Genet 1978 1.11
37 Polycythemia vera: studies of hemopoiesis in continuous long-term culture of human marrow. J Cell Physiol Suppl 1982 1.11
38 The Alström syndrome. Report of three cases with further delineation of the clinical, pathophysiological, and genetic aspects of the disorder. Medicine (Baltimore) 1973 1.10
39 Autoimmunity in the relatives of patients with immunodeficiency diseases. Clin Exp Immunol 1977 1.10
40 Chronic myelocytic leukemia (CML): failure to detect residual normal committed stem cells in vitro. Blood 1979 1.09
41 Unicellular or multicellular origin of human granulocyte-macrophage colonies in vitro. Blood 1979 1.09
42 Multicellular origin of fibrosarcomas in mice induced by the chemical carcinogen 3-methylcholanthrene. J Exp Med 1979 1.08
43 Human megakaryocytic progenitors (CFU-M) assayed in methylcellulose: physical characteristics and requirements for growth. J Cell Physiol 1984 1.07
44 Multicellular origin of parathyroid "adenomas". N Engl J Med 1977 1.07
45 Multiple cell origin of hereditary neurofibromas. N Engl J Med 1971 1.06
46 Cell lineages in hematopoietic neoplasia studied with glucose-6-phosphate dehydrogenase cell markers. J Cell Physiol Suppl 1982 1.05
47 Chronic lymphocytic leukaemia: Clonal origin in a committed B-lymphocyte progenitor. Lancet 1978 1.04
48 Human neoplastic and normal cells in tissue culture. I. Cell lines derived from malignant melanomas and normal melanocytes. J Natl Cancer Inst 1976 1.04
49 Genetic aspects of autoimmunity. Prog Med Genet 1969 1.03
50 Human erythroid colony formation in vitro: evidence for clonal origin. J Cell Physiol 1976 1.03
51 Measurable linkage between ocular albinism and Xg. Am J Hum Genet 1967 1.03
52 Clonal origin of chronic myelocytic leukemia. N Engl J Med 1973 1.02
53 Simian virus 40-transformed adherent cells from human long-term marrow cultures: cloned cell lines produce cells with stromal and hematopoietic characteristics. Blood 1987 1.01
54 Translocation, t(4qminus;13qplus), in three generations resulting in partial trisomy of the long arm of chromosome 4 in the fourth generation. J Med Genet 1974 1.00
55 The use of cell markers in the study of human hematopoietic neoplasia. Adv Cancer Res 1987 1.00
56 Pancytopenia as a clonal disorder of a multipotent hematopoietic stem cell. J Clin Invest 1984 0.99
57 Single or multicellular origin of human T lymphocyte colonies in vitro: modification by 12-o-tetradecanoylphorbol 13-acetate (TPA). J Immunol 1981 0.99
58 Familial predisposition to thyroid disease in Down's syndrome: controlled immunoclinical studies. Am J Hum Genet 1971 0.99
59 A clonal complete remission in a patient with acute nonlymphocytic leukemia originating in a multipotent stem cell. N Engl J Med 1984 0.98
60 Polycythemia vera. Increased expression of normal committed granulocytic stem cells in vitro after exposure of marrow to tritiated thymidine. J Clin Invest 1979 0.98
61 Allogeneic marrow grafting for hematologic malignancy using HL-A matched donor-recipient sibling pairs. Blood 1971 0.98
62 Feline glucose-6-phosphate dehydrogenase cellular mosaicism. Application to the study of retrovirus-induced pure red cell aplasia. J Clin Invest 1985 0.97
63 Establishment of a lymphoid cell line from leukemic cells of a patient with chronic lymphocytic leukemia. Int J Cancer 1980 0.96
64 Involvement of the B-lymphoid system in chronic myelogenous leukaemia. Nature 1980 0.95
65 Papillomas induced by initiation-promotion differ from those induced by carcinogen alone. Nature 1983 0.95
66 Xg locus: failure to detect inactivation in females with chronic myelocytic leukaemia. Nature 1970 0.93
67 Clonal origin and trisomy of chromosome 15 in murine B-cell malignancies. Int J Cancer 1980 0.92
68 Autosomal dominant polycystic kidney disease: symptoms and clinical findings. Q J Med 1984 0.92
69 The genetics of Graves' disease. Clin Endocrinol Metab 1978 0.92
70 Polycythemia vera. Further in vitro studies of hematopoietic regulation. J Clin Invest 1980 0.92
71 Pseudoxanthoma elasticum. An underdiagnosed genetically heterogeneous disorder with protean manifestations. Arch Intern Med 1974 0.91
72 Chromosome analyses of lymphoid cell lines derived from patients with chronic lymphocytic leukemia. Int J Cancer 1980 0.91
73 Evidence for a clonal origin of head and neck tumors. Int J Cancer 1972 0.91
74 Probable clonal origin of acute myeloblastic leukemia following radiation and chemotherapy of colon cancer. Blood 1978 0.91
75 Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosome. Blood 1980 0.91
76 Studies of skin tumorigenesis in PGK mosaic mice: many promoter-independent papillomas and carcinomas do not develop from pre-existing promoter-dependent papillomas. Int J Cancer 1987 0.91
77 Intrafamilial phenotypic expression of autosomal dominant polycystic kidney disease. Am J Kidney Dis 1992 0.90
78 X chromosome inactivation in cells from an individual heterozygous for two X-linked genes. Nat New Biol 1972 0.90
79 6-phosphogluconate dehydrogenase: hemizygous manifestation in a patient with leukemia. Science 1969 0.90
80 Evidence for selection in cultured diploid fibroblast strains. Exp Cell Res 1978 0.90
81 Evidence for the involvement of B lymphoid cells in polycythemia vera and essential thrombocythemia. J Clin Invest 1985 0.90
82 The occurrence of gonadal dysgenesis in association with monozygotic twinning. J Med Genet 1975 0.89
83 Heterogeneity of B cell involvement in acute nonlymphocytic leukemia. Blood 1985 0.89
84 Polycythemia vera. Physical separation of normal and neoplastic committed granulocyte-macrophage progenitors. J Clin Invest 1980 0.89
85 Acute nonlymphocytic leukemia: expression in cells restricted to granulocytic and monocytic differentiation. N Engl J Med 1979 0.88
86 Thyroid antibodies, Down's syndrome, and maternal age. Nature 1967 0.88
87 Familial carcinoma of the pancreas. Clin Genet 1976 0.88
88 Increased serum thyroxine-binding globulin capacity: inheritance and linkage relationships. J Clin Endocrinol Metab 1970 0.87
89 Fertility and pregnancy complications in women with autosomal dominant polycystic kidney disease. Obstet Gynecol 1983 0.87
90 Second malignant clone underlying a Burkitt-tumor exacerbation. Lancet 1972 0.87
91 Viral "tumorigenesis" in man: cell markers in condylomata acuminata. Int J Cancer 1976 0.87
92 B-lymphoid cell involvement in chronic myelogenous leukemia: implications for the pathogenesis of the disease. Cancer Genet Cytogenet 1982 0.85
93 Hypogonadotropic hypogonadism associated with anosmia in the female. N Engl J Med 1970 0.85
94 Thyroid autoimmunity: increased frequency in relatives of insulin-dependent diabetes patients. Ann Intern Med 1975 0.84
95 Evidence for clonal development of childhood acute lymphoblastic leukemia. Blood 1985 0.84
96 Further evidence for the existence of a clonal Ph-negative stage in some cases of Ph-positive chronic myelocytic leukemia. Leukemia 1993 0.83
97 Thyroid antibodies and Australia antigen in Down's syndrome. J Ment Defic Res 1971 0.82
98 Probable clonal origin of neurofibrosarcoma in a patient with hereditary neurofibromatosis. J Natl Cancer Inst 1982 0.82
99 Autosomal dominant polycystic kidney disease: early diagnosis and data for genetic counselling. Lancet 1980 0.81
100 Human mixed cell colonies: unicellular or multicellular origin--analysis by G-6-PD. Br J Haematol 1984 0.81
101 Hereditary retinoschisis linkage studies in a family and considerations in genetic counselling. Can J Ophthalmol 1976 0.81
102 Immunoglobulin synthesis and glucose-6-phosphate dehydrogenase as cell markers in human lymphoblastoid cell lines. Exp Cell Res 1974 0.81
103 The induction of chromosomal aberrations in vitro by allogeneic lymphocyte extract. Transplantation 1967 0.81
104 Multiple cell origin of traumatically induced keloids. J Am Acad Dermatol 1984 0.80
105 Hyperploidy effect of lymphocyte extract on fibroblasts in vitro. Nature 1966 0.80
106 Influence of dose of initiator on two-stage skin carcinogenesis in BALB/c mice with cellular mosaicism. Carcinogenesis 1988 0.80
107 Chronic myelogenous leukemia: in vitro studies of hematopoietic regulation in a patient undergoing intensive chemotherapy. J Clin Invest 1981 0.79
108 Long-term stable hematopoietic chimerism following marrow transplantation for acute lymphoblastic leukemia: a case report with in vitro marrow culture studies. Blood 1983 0.79
109 Clinical manifestations of autosomal dominant polycystic kidney disease in patients older than 50 years. Am J Kidney Dis 1990 0.79
110 Clonal analysis of childhood acute lymphoblastic leukemia with "cytogenetically independent" cell populations. J Clin Invest 1989 0.78
111 Probable clonal development of foreign-body-induced murine sarcomas. J Natl Cancer Inst 1984 0.78
112 Carcinoma of the pancreas in four brothers. Birth Defects Orig Artic Ser 1976 0.78
113 Allogeneic marrow grafting for acute lymphoblastic leukemia: leukemic relapse. Transplant Proc 1973 0.78
114 Philadelphia chromosome (Ph1)-negative chronic myelogenous leukemia (CML): a clonal disease with origin in a multipotent stem cell. Blood 1980 0.78
115 Allogeneic marrow grafting using HL-A matched donor-recipient sibling pairs. Trans Assoc Am Physicians 1971 0.78
116 Clonal development of lymphomas induced by Rauscher leukemia virus. Int J Cancer 1983 0.78
117 Single or multiple cell origin for tumors? N Engl J Med 1971 0.78
118 Clonal nature of mink cell focus-inducing virus-induced AKR leukemia: studies with X-chromosome inactivation cellular mosaicism. J Natl Cancer Inst 1983 0.78
119 Probable clonal origin of aldosteronomas versus multicellular origin of parathyroid "adenomas". Surgery 1982 0.78
120 Evidence for clonal development and stem cell origin of M7 megakaryocytic leukemia. Leukemia 1988 0.78
121 Trisomy of 1q in preleukaemia with progression to acute leukaemia. Scand J Haematol 1978 0.78
122 Deficiency of malic enzyme: a possible marker for malignancy in lymphoid cells. Ann Hum Genet 1981 0.78
123 Evidence for clonal development of Wilms' tumor. Am J Pediatr Hematol Oncol 1991 0.78
124 Chronic lymphocytosis with neutropenia: evidence for a novel, abnormal T-cell population associated with antibody-mediated neutrophil destruction. Clin Immunol Immunopathol 1983 0.77
125 Host origin of marrow stromal cells obtained from marrow transplant recipients and transformed in vitro by simian virus-40. Exp Hematol 1988 0.77
126 Replicative life-span of cultured skin fibroblasts from young mothers of subjects with Down's syndrome: failure to detect accelerated ageing. Am J Hum Genet 1973 0.77
127 Increased sensitivity to two-stage skin carcinogenesis of mice heterozygous for the repeated epilation mutation (Er). Int J Cancer 1990 0.77
128 Cell marker studies of human tumorigenesis. Transplant Rev 1976 0.76
129 Evidence that weak promotion of carcinogen-initiated cells prevents their progression to malignancy. Carcinogenesis 1990 0.76
130 Clonal nature of spontaneous AKR leukemia: studies utilizing the X-linked enzyme phosphoglycerate kinase. Int J Cancer 1982 0.76
131 Chromosome fragility in New Zealand black mice: effect of ultraviolet and gamma radiations on fetal fibroblasts in vitro. J Natl Cancer Inst 1980 0.76
132 SV40 T-antigen expression in cultured fibroblasts from patients with Down syndrome and their parents. Am J Hum Genet 1979 0.75
133 Chromosomal abnormalities in spleens of New Zealand black mice, a strain characterized by autoimmunity and malignancy. Proc Natl Acad Sci U S A 1973 0.75
134 Human genetic markers as tracers of tumour histogenesis. J Clin Pathol Suppl (R Coll Pathol) 1974 0.75
135 Cellular biology of acute myelogenous leukemia. J Pediatr Hematol Oncol 1995 0.75
136 Leukaemic transformation of engrafted human cells in vivo. Lancet 1971 0.75
137 Nature of remission in acute myeloid leukemia: more questions than answers. Leukemia 1992 0.75
138 Development of murine skin neoplasia studied with enzymes used as cell markers. Carcinog Compr Surv 1989 0.75
139 [Prenatal diagnosis of genetic diseases]. Gac Med Mex 1974 0.75
140 Genetic markers in chronic myelocytic leukaemia: evidence opposing autosomal inactivation and favouring 6-PGD-Rh linkage. Ann Hum Genet 1972 0.75
141 Myelofibrosis with complex chromosome abnormality in a patient with erythrocytosis due to hemoglobin Rainier and treated with 32P. Am J Hematol 1978 0.75
142 Is lyonisation total in man? Lancet 1970 0.75
143 Proceedings: Genetic markers and the origin of human neoplasms. Br J Cancer 1975 0.75
144 Confirming evidence for the clonal development and stem cell origin of Philadelphia chromosome-negative chronic myelogenous leukemia. Am J Hematol 1984 0.75
145 Neoplastic behavior of chromosomally abnormal clones in New Zealand Black mice. Int J Cancer 1978 0.75
146 Effect of solvents on methylcholanthrene-induced carcinogenesis in mice. Int J Cancer 1981 0.75
147 Use of glucose-6-phosphate dehydrogenase markers to study human myeloproliferative disorders. Haematol Blood Transfus 1979 0.75
148 Chromosomal abnormalities induced in vitro by extracts of mouse allogeneic lymphocytes. Exp Cell Res 1968 0.75
149 Sequential studies of skin tumorigenesis in PGK mosaic mice: the effect of repeated exposure to a carcinogen on regressed mouse skin papillomas. Carcinogenesis 1987 0.75
150 [Role of the anithyroideal antibodies in the etiology of chromosome aberrations]. Gac Med Mex 1976 0.75
151 Chromosome fragility in New Zealand black mice: effect of syngeneic, allogeneic, and xenogeneic sera on fetal fibroblasts in vitro. J Natl Cancer Inst 1981 0.75
152 The genetics of diabetes mellitus. Prog Med Genet 1980 0.75
153 The effect of long-term marrow culture on the origin of colony-forming cells in acute myeloblastic leukemia: studies of two patients heterozygous for glucose-6-phosphate dehydrogenase. Leukemia 1988 0.75
154 Glucose-6-phosphate dehydrogenase (G-6-PD) markers in Burkitt lymphoma and other malignancies. Haematol Blood Transfus 1977 0.75
155 Acquired trisomy 12 and absent Y chromosome in a patients with acute undifferentiated leukaemia. Scand J Haematol 1981 0.75
156 Clonal remissions in acute nonlymphocytic leukemia: implications for curability. Semin Hematol 1991 0.75
157 Specificity of acquired clonal chromosome abnormalities in New Zealand Black mice. Int J Cancer 1978 0.75
158 "Masked" Ph1 chromosome in a complex three-way translocation. Cancer Genet Cytogenet 1983 0.75
159 Sequential studies of skin tumorigenesis in phosphoglycerate kinase mosaic mice: effect of resumption of promotion on regressed papillomas. Cancer Res 1987 0.75
160 Longitudinal studies of chromosomal abnormalities and reticulum cell proliferation in New Zealand Black mice. Int J Cancer 1978 0.75