Published in Am J Med on July 01, 1987
Identification of two related pentapeptides from the brain with potent opiate agonist activity. Nature (1975) 10.33
Determination of therapeutic and toxic serum digoxin concentrations by radioimmunoassay. N Engl J Med (1969) 6.15
Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1. Proc Natl Acad Sci U S A (1991) 5.78
Internists' and surgeons' attitudes toward guns and firearm injury prevention. Ann Intern Med (1998) 5.15
Support for new policies to regulate firearms. Results of two national surveys. N Engl J Med (1998) 5.06
Plasma digoxin concentrations in patients with atrial fibrillation. Br Med J (1970) 4.82
J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential. Biochemistry (1991) 4.11
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (2001) 3.64
Natural killer cell depletion enhances virus synthesis and virus-induced hepatitis in vivo. J Immunol (1983) 3.58
A meta-analytic review of research on hostility and physical health. Psychol Bull (1996) 3.27
Digitalis intoxication. A prospective clinical study with serum level correlations. N Engl J Med (1971) 3.27
Chlamydia trachomatis as a cause of acute "idiopathic" epididymitis. N Engl J Med (1978) 3.16
Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J Biol Chem (1996) 2.82
Disruption of Ini1 leads to peri-implantation lethality and tumorigenesis in mice. Mol Cell Biol (2001) 2.76
Pathogenesis of murine cytomegalovirus infection in natural killer cell-depleted mice. J Virol (1984) 2.73
Digoxin intoxication: the relationship of clinical presentation to serum digoxin concentration. J Clin Invest (1970) 2.66
The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues. Br J Pharmacol (1977) 2.59
Reversal of advanced digoxin intoxication with Fab fragments of digoxin-specific antibodies. N Engl J Med (1976) 2.49
Characterization of antibodies of high affinity and specificity for the digitalis glycoside digoxin. Biochemistry (1970) 2.39
Suspected low-grade glioma: is deferring treatment safe? Ann Neurol (1992) 2.37
Effect of pregnancy on exposure to malaria mosquitoes. Lancet (2000) 2.36
Control of cardiac muscle cell function by an endogenous nitric oxide signaling system. Proc Natl Acad Sci U S A (1993) 2.32
Recommendation on the nomenclature for oral anticoagulants: communication from the SSC of the ISTH. J Thromb Haemost (2015) 2.19
Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest (1998) 2.17
Medullomyoblastoma. A histologic, immunohistochemical, and ultrastructural study. Cancer (1984) 2.03
Antithrombotic therapy. An abbreviated reference for clinicians. Arch Intern Med (1995) 2.01
Nitric oxide and cardiac function. Circ Res (1996) 2.01
Aging and the anticoagulant response to warfarin therapy. Ann Intern Med (1992) 1.97
Digoxin therapy and mortality after myocardial infarction. Experience in the MILIS Study. N Engl J Med (1986) 1.96
P504S: a new molecular marker for the detection of prostate carcinoma. Am J Surg Pathol (2001) 1.86
Etiology, manifestations and therapy of acute epididymitis: prospective study of 50 cases. J Urol (1979) 1.83
Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J Biol Chem (1995) 1.80
Transferrin receptor in normal and neoplastic brain tissue: implications for brain-tumor immunotherapy. J Neurosurg (1990) 1.76
Vascular bed-specific expression of an endothelial cell gene is programmed by the tissue microenvironment. J Cell Biol (1997) 1.74
The efficacy and safety of apixaban, an oral, direct factor Xa inhibitor, as thromboprophylaxis in patients following total knee replacement. J Thromb Haemost (2007) 1.73
Elimination of syngeneic sarcomas in rats by a subset of T lymphocytes. J Exp Med (1980) 1.72
Effects of larval mosquitoes (Aedes triseriatus) and stemflow on microbial community dynamics in container habitats. Appl Environ Microbiol (1999) 1.70
Virus-induced abrogation of transplantation tolerance induced by donor-specific transfusion and anti-CD154 antibody. J Virol (2000) 1.64
Digitalis (third of four parts). N Engl J Med (1973) 1.63
Calcium and proton activities in rat cardiac mitochondria. Effect of matrix environment on behaviour of fluorescent probes. Biochem J (1989) 1.60
Treatment of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments: experience in 26 cases. N Engl J Med (1982) 1.56
Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest (1993) 1.54
Personality and patient adherence: correlates of the five-factor model in renal dialysis. J Behav Med (1995) 1.51
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids. Proc Natl Acad Sci U S A (1992) 1.50
Localization of HIV-1 co-receptors CCR5 and CXCR4 in the brain of children with AIDS. Am J Pathol (1998) 1.50
Lymphocyte apoptosis during the silencing of the immune response to acute viral infections in normal, lpr, and Bcl-2-transgenic mice. Am J Pathol (1995) 1.48
The isolation of digoxin-specific antibody and its use in reversing the effects of digoxin. Proc Natl Acad Sci U S A (1971) 1.46
Positive CSF HSV PCR in patients with GBM: a note of caution. Neurology (2000) 1.43
Meningeal gliomatosis presenting as multiple cerebral infarcts: a case report. Neurology (1996) 1.42
The gender gap in reporting household gun ownership. Am J Public Health (1998) 1.42
Digitalis glycosides: mechanisms and manifestations of toxicity. Part I. Prog Cardiovasc Dis (1984) 1.41
Continual electric field stimulation preserves contractile function of adult ventricular myocytes in primary culture. Am J Physiol (1994) 1.41
Age-related risks of long-term oral anticoagulant therapy. Arch Intern Med (1988) 1.40
Immunogenicity and kinetics of distribution and elimination of sheep digoxin-specific IgG and Fab fragments in the rabbit and baboon. Clin Exp Immunol (1979) 1.39
Proximal weakness as the primary manifestation of myotonic dystrophy in older adults. Muscle Nerve (1994) 1.38
Eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Analysis of four patients and implications for differential diagnosis and pathogenesis. Arch Intern Med (1990) 1.38
Initial experience with a steerable intracardiac echocardiographic catheter. J Invasive Cardiol (1999) 1.38
Expression of the eukaryotic translation initiation factors 4E and 2alpha in non-Hodgkin's lymphomas. Am J Pathol (1999) 1.38
Comment on the use of the term "Immaculate conceptions" by Meekers, Vol. 42, No. 3-4. Soc Biol (1998) 1.38
Plasma concentrations of digoxin after oral administration in the fasting and postprandial ste. Br Med J (1971) 1.36
What's so unhealthy about hostility? Construct validity and psychosocial correlates of the Cook and Medley Ho scale. Health Psychol (1985) 1.35
Treatment of 150 cases of life-threatening digitalis intoxication with digoxin-specific Fab antibody fragments. Final report of a multicenter study. Circulation (1990) 1.35
Dynamic targeting of the agonist-stimulated m2 muscarinic acetylcholine receptor to caveolae in cardiac myocytes. J Biol Chem (1997) 1.33
The control of microvascular permeability and blood pressure by neutral endopeptidase. Nat Med (1997) 1.31
Protective effect of eicosapentaenoic acid on ouabain toxicity in neonatal rat cardiac myocytes. Proc Natl Acad Sci U S A (1990) 1.29
Mechanisms of transmembrane calcium movement in cultured chick embryo ventricular cells. J Physiol (1982) 1.29
Digitalis. I. N Engl J Med (1973) 1.29
Alpha-methylacyl-CoA racemase: a multi-institutional study of a new prostate cancer marker. Histopathology (2004) 1.29
Cytokines and cardiac contractile function. Circulation (1997) 1.29
Localization of cardiac myosin-specific antibody in myocardial infarction. J Clin Invest (1976) 1.27
Relationship of binding of a calcium channel blocker to inhibition of contraction in intact cultured embryonic chick ventricular cells. Circ Res (1983) 1.27
Recognition and management of digitalis toxicity. Am J Cardiol (1992) 1.26
Endothelin and increased contractility in adult rat ventricular myocytes. Role of intracellular alkalosis induced by activation of the protein kinase C-dependent Na(+)-H+ exchanger. Circ Res (1991) 1.26
Adult rat ventricular myocytes cultured in defined medium: phenotype and electromechanical function. Am J Physiol (1993) 1.26
Inducible nitric oxide synthase in tangle-bearing neurons of patients with Alzheimer's disease. J Exp Med (1996) 1.25
Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype. Neurology (1997) 1.24
Deficiency of phenotypic cytotoxic-suppressor T lymphocytes in the BB/W rat. J Immunol (1986) 1.23
Isolation and characterization of human and rat cardiac microvascular endothelial cells. Am J Physiol (1993) 1.22
Role of nitric oxide in parasympathetic modulation of beta-adrenergic myocardial contractility in normal dogs. J Clin Invest (1995) 1.22
Induction of angiosarcoma by a c-erbB transducing virus. J Virol (1985) 1.22
Distal forearm fracture as risk factor for vertebral osteoporosis. BMJ (1994) 1.22
Kinetics in interactions between antibodies and haptens. Biochemistry (1975) 1.21
Peripheral antinociceptive effects of N-methyl morphine. Life Sci (1983) 1.21
Regulation of cytokine-inducible nitric oxide synthase in cardiac myocytes and microvascular endothelial cells. Role of extracellular signal-regulated kinases 1 and 2 (ERK1/ERK2) and STAT1 alpha. J Biol Chem (1996) 1.20
Should cerebral ischemic events in cancer patients be considered a manifestation of hypercoagulability? Stroke (1994) 1.19
Role of transiently altered sarcolemmal membrane permeability and basic fibroblast growth factor release in the hypertrophic response of adult rat ventricular myocytes to increased mechanical activity in vitro. J Clin Invest (1996) 1.18
The effect of local anesthetics on the lateral mobility of lymphocyte membrane proteins. Exp Cell Res (1980) 1.18
Suicidal and accidental digoxin ingestion. Report of five cases with serum digoxin level correlations. Circulation (1971) 1.18
An intrinsic adrenergic system in mammalian heart. J Clin Invest (1996) 1.17
Effects of codeine, morphine and a novel opioid pentapeptide BW443C, on cough, nociception and ventilation in the unanaesthetized guinea-pig. Br J Pharmacol (1988) 1.16
Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve. Proc Natl Acad Sci U S A (1996) 1.15
Role of epicardial mesothelial cells in the modification of phenotype and function of adult rat ventricular myocytes in primary coculture. Circ Res (1992) 1.15
Malignant carcinoid tumor metastatic to a meningioma. Cancer (1981) 1.14
Alzheimer's disease and Lewy body disease: a comparative clinicopathological study. Ann Neurol (1994) 1.14
Nitric oxide synthase (NOS3)-mediated cholinergic modulation of Ca2+ current in adult rabbit atrioventricular nodal cells. Circ Res (1996) 1.14
Determination of antibody-hapten association kinetics: a simplified experimental approach. J Immunol (1975) 1.13
Variability of 24-hour urinary creatinine excretion by normal subjects. J Clin Pharmacol (1976) 1.13
Treatment of 63 severely digitalis-toxic patients with digoxin-specific antibody fragments. J Am Coll Cardiol (1985) 1.13