Published in Exp Cell Res on October 15, 1978
The human keratins: biology and pathology. Histochem Cell Biol (2008) 5.13
Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes. J Cell Biol (1984) 4.00
Monoclonal antibodies provide specific intramolecular markers for the study of epithelial tonofilament organization. J Cell Biol (1982) 3.80
Epithelial cytoskeletal framework and nuclear matrix-intermediate filament scaffold: three-dimensional organization and protein composition. J Cell Biol (1984) 3.48
Immunolocalization of keratin polypeptides in human epidermis using monoclonal antibodies. J Cell Biol (1982) 3.47
Keratin cytoskeletons in epithelial cells of internal organs. Proc Natl Acad Sci U S A (1979) 3.45
Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94
Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin. Proc Natl Acad Sci U S A (1981) 2.94
Use of monoclonal antibodies for the histopathological diagnosis of human malignancy. J Clin Pathol (1982) 2.69
The 50- and 58-kdalton keratin classes as molecular markers for stratified squamous epithelia: cell culture studies. J Cell Biol (1983) 2.58
Intermediate-sized filaments of the prekeratin type in myoepithelial cells. J Cell Biol (1980) 2.54
Classification of epidermal keratins according to their immunoreactivity, isoelectric point, and mode of expression. J Cell Biol (1984) 2.48
Monoclonal antibodies to intermediate filament proteins of human cells: unique and cross-reacting antibodies. J Cell Biol (1982) 2.45
Isolation of the intercellular glycoproteins of desmosomes. J Cell Biol (1981) 2.40
Pair formation and promiscuity of cytokeratins: formation in vitro of heterotypic complexes and intermediate-sized filaments by homologous and heterologous recombinations of purified polypeptides. J Cell Biol (1985) 2.37
Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis. Am J Pathol (1994) 2.26
Redistribution of intermediate filament subunits during skeletal myogenesis and maturation in vitro. J Cell Biol (1979) 2.26
Immunocytochemical demonstration of vimentin in astrocytes and ependymal cells of developing and adult mouse nervous system. J Cell Biol (1981) 2.20
Immunological identification and localization of the predominant nuclear protein of the amphibian oocyte nucleus. Proc Natl Acad Sci U S A (1980) 2.18
Protein complexes of intermediate-sized filaments: melting of cytokeratin complexes in urea reveals different polypeptide separation characteristics. Proc Natl Acad Sci U S A (1983) 2.05
Different keratin polypeptides in epidermis and other epithelia of human skin: a specific cytokeratin of molecular weight 46,000 in epithelia of the pilosebaceous tract and basal cell epitheliomas. J Cell Biol (1982) 1.93
Identification of protein IT of the intestinal cytoskeleton as a novel type I cytokeratin with unusual properties and expression patterns. J Cell Biol (1990) 1.88
Association of microtubules and intermediate filaments in chicken gizzard cells as detected by double immunofluorescence. Proc Natl Acad Sci U S A (1980) 1.87
Immunoperoxidase localization of keratin in human neoplasms: a preliminary survey. Am J Pathol (1980) 1.76
Tissue specificity of epithelial keratins: differential expression of mRNAs from two multigene families. Mol Cell Biol (1983) 1.75
Expression of epidermal keratins and filaggrin during human fetal skin development. J Cell Biol (1985) 1.68
Detection of a cytokeratin determinant common to diverse epithelial cells by a broadly cross-reacting monoclonal antibody. EMBO J (1982) 1.63
Reversible translocation of cytoplasmic actin into the nucleus caused by dimethyl sulfoxide. Proc Natl Acad Sci U S A (1980) 1.57
A subfamily of relatively large and basic cytokeratin polypeptides as defined by peptide mapping is represented by one or several polypeptides in epithelial cells. EMBO J (1982) 1.54
Isolation and characterization of desmosome-associated tonofilaments from rat intestinal brush border. J Cell Biol (1981) 1.52
Molecular characterization and expression of the stratification-related cytokeratins 4 and 15. J Cell Biol (1988) 1.50
Cytokeratins in normal and malignant transitional epithelium. Maintenance of expression of urothelial differentiation features in transitional cell carcinomas and bladder carcinoma cell culture lines. Am J Pathol (1988) 1.47
Tissue type-specific expression of intermediate filament proteins in a cultured epithelial cell line from bovine mammary gland. J Cell Biol (1983) 1.46
Immunocytochemical identification of epithelium-derived human tumors with antibodies to desmosomal plaque proteins. Proc Natl Acad Sci U S A (1983) 1.44
Ten-nanometer filaments and mitosis: maintenance of structural continuity in dividing endothelial cells. Proc Natl Acad Sci U S A (1979) 1.44
Identification of a basic protein of Mr 75,000 as an accessory desmosomal plaque protein in stratified and complex epithelia. J Cell Biol (1988) 1.43
Isolation and characterization of keratin-like proteins from cultured cells with fibroblastic morphology. J Cell Biol (1984) 1.40
Immunohistochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies. Am J Pathol (1984) 1.39
Intermediate filaments formed de novo from tail-less cytokeratins in the cytoplasm and in the nucleus. J Cell Biol (1991) 1.37
Vimentin dephosphorylation by protein phosphatase 2A is modulated by the targeting subunit B55. Mol Biol Cell (1999) 1.35
Specific attachment of desmin filaments to desmosomal plaques in cardiac myocytes. EMBO J (1983) 1.33
Formation and involution of Mallory bodies ("alcoholic hyalin") in murine and human liver revealed by immunofluorescence microscopy with antibodies to prekeratin. Proc Natl Acad Sci U S A (1979) 1.33
Restin: a novel intermediate filament-associated protein highly expressed in the Reed-Sternberg cells of Hodgkin's disease. EMBO J (1992) 1.32
Human monoclonal IgM with autoantibody activity against intermediate filaments. Proc Natl Acad Sci U S A (1982) 1.31
Expression of simple epithelial type cytokeratins in stratified epithelia as detected by immunolocalization and hybridization in situ. J Cell Biol (1988) 1.29
Modification of human prekeratin during epidermal differentiation. Biochem J (1981) 1.27
Intermediate-size filaments in a germ cell: Expression of cytokeratins in oocytes and eggs of the frog Xenopus. Proc Natl Acad Sci U S A (1983) 1.25
Nucleus-associated intermediate filaments from chicken erythrocytes. J Cell Biol (1980) 1.23
Translational products of mRNAs coding for non-epidermal cytokeratins. EMBO J (1983) 1.22
Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies. Am J Pathol (2000) 1.21
Isolation and partial characterization of a cage of filaments that surrounds the mammalian mitotic spindle. J Cell Biol (1980) 1.20
Change of cytokeratin filament organization during the cell cycle: selective masking of an immunologic determinant in interphase PtK2 cells. J Cell Biol (1983) 1.19
Liver tumors distinguished by immunofluorescence microscopy with antibodies to proteins of intermediate-sized filaments. Proc Natl Acad Sci U S A (1980) 1.19
Differences of expression of cytokeratin polypeptides in various epithelial skin tumors. Arch Dermatol Res (1984) 1.18
Lenticular intermediate-sized filaments: biosynthesis and interaction with plasma membrane. Proc Natl Acad Sci U S A (1982) 1.15
Intermediate filaments. J Cell Biol (1984) 1.14
Identification of glial filament protein and vimentin in the same intermediate filament system in human glioma cells. Proc Natl Acad Sci U S A (1984) 1.14
Enhancer elements directing cell-type-specific expression of cytokeratin genes and changes of the epithelial cytoskeleton by transfections of hybrid cytokeratin genes. EMBO J (1989) 1.10
Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily. EMBO J (1985) 1.10
Co-expression of cytokeratins and neurofilament proteins in a permanent cell line: cultured rat PC12 cells combine neuronal and epithelial features. J Cell Biol (1986) 1.08
5-Azacytidine is able to induce the conversion of teratocarcinoma-derived mesenchymal cells into epithelia cells. EMBO J (1984) 1.05
Developmental regulation of cytokeratins in cells of the rat mammary gland studied with monoclonal antibodies. Proc Natl Acad Sci U S A (1984) 1.02
Characterization of bovine keratin genes: similarities of exon patterns in genes coding for different keratins. EMBO J (1984) 1.01
Characterization of a myoepithelial cell line derived from a neonatal rat mammary gland. J Cell Biol (1981) 1.01
Epithelial structure revealed by chemical dissection and unembedded electron microscopy. J Cell Biol (1984) 1.01
The intermediate filament cytoskeleton of malignant mesotheliomas and its diagnostic significance. Am J Pathol (1985) 1.01
Measles virus infection induces terminal differentiation of human thymic epithelial cells. J Virol (1999) 1.00
Cytokeratin No. 9, an epidermal type I keratin characteristic of a special program of keratinocyte differentiation displaying body site specificity. J Cell Biol (1986) 1.00
Intermediate filament cytoskeleton of amnion epithelium and cultured amnion epithelial cells: expression of epidermal cytokeratins in cells of a simple epithelium. J Cell Biol (1985) 0.97
Differential immunological crossreactivity of HeLa keratin antibodies with human epidermal keratins. Proc Natl Acad Sci U S A (1983) 0.96
Immunohistochemical localization of prekeratin filaments in benign and malignant cells in effusions. Comparison with intermediate filament distribution by electron microscopy. Am J Pathol (1982) 0.96
Intermediate-sized filaments in Drosophila tissue culture cells. J Cell Biol (1984) 0.95
Proteins IEF (isoelectric focusing) 31 and IEF 46 are keratin-type components of the intermediate-sized filaments: keratins of various human cultured epithelial cells. J Cell Biol (1983) 0.92
Rearrangement of the keratin cytoskeleton after combined treatment with microtubule and microfilament inhibitors. J Cell Biol (1983) 0.92
Cultured human amniotic fluid cells characterized with antibodies against intermediate filaments in indirect immunofluorescence microscopy. J Clin Invest (1981) 0.92
Keratin filaments of mouse epithelial cells are rapidly affected by epidermal growth factor. J Cell Biol (1981) 0.92
Renal allograft rejection: investigation of alloantigen presentation by cultured human renal epithelial cells. Immunology (1991) 0.91
Primary human adult lung epithelial cells in vitro: response to interferon-gamma and cytomegalovirus. Immunology (1993) 0.91
Intermediate filaments: a historical perspective. Exp Cell Res (2007) 0.91
Identification of cytokeratin antigens in Novikoff ascites hepatoma. Proc Natl Acad Sci U S A (1982) 0.89
Histogenesis of glomerular crescents. Immunohistochemical demonstration of cytokeratin in crescent cells. Am J Pathol (1985) 0.89
Extinction of the HPV18 upstream regulatory region in cervical carcinoma cells after fusion with non-tumorigenic human keratinocytes under non-selective conditions. EMBO J (1991) 0.89
Keratin in human lung tumors. Patterns of localization of different-molecular-weight keratin proteins. Am J Pathol (1983) 0.88
Renal allograft rejection: induction and function of adhesion molecules on cultured epithelial cells. Clin Exp Immunol (1992) 0.86
Confocal and conventional immunofluorescence and ultrastructural localisation of intracellular strength-giving components of human amniochorion. J Anat (1993) 0.86
Intermediate filaments in malignant melanomas. Identification and use as marker in surgical pathology. J Clin Invest (1983) 0.85
Renal allograft rejection: expression and function of VCAM-1 on tubular epithelial cells. Clin Exp Immunol (1993) 0.85
Use of monoclonal antibodies for analyzing the distribution of the intermediate filament protein vimentin in human non-Hodgkin's lymphomas. Am J Pathol (1985) 0.85
Differential extraction of keratin subunits and filaments from normal human epidermis. J Cell Biol (1990) 0.84
Characterization of a dermal derived malignant mesenchymal tumor arising in ultraviolet irradiated mice. Am J Pathol (1989) 0.83
Association of cytokeratin p39 with DNA in intact Novikoff hepatoma cells. Proc Natl Acad Sci U S A (1984) 0.83
Formation and identification of cytoskeletal components from liver cytosolic precursors. Proc Natl Acad Sci U S A (1982) 0.83
Renal allograft rejection: possible involvement of lymphokine-activated killer cells. Immunology (1989) 0.80
Improved fixation for immunofluorescence microscopy using light-activated 1,3,5-triazido-2,4,6-trinitrobenzene (TTB). J Cell Biol (1984) 0.80
Renal allograft rejection: protection of renal epithelium from natural killer cells by cytokine-induced up-regulation of class I major histocompatibility antigens. Immunology (1993) 0.79
Esthesioneuroblastoma: ultrastructural, immunohistological and biochemical investigation of one case. Arch Otorhinolaryngol (1984) 0.78
Expression and distribution of vimentin and keratin filaments in heterokaryons of human fibroblasts and amnion epithelial cells. J Cell Biol (1982) 0.78
Anti-Fx1A induces association of Heymann nephritis antigens with microfilaments of cultured glomerular visceral epithelial cells. Am J Pathol (1987) 0.78
Studies on the origin of human amniotic fluid cells by immunofluorescent staining of keratin filaments. J Med Genet (1982) 0.77
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem (1969) 142.11
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells. Cell (1982) 19.91
Measurement of molecular weights by electrophoresis on SDS-acrylamide gel. Methods Enzymol (1972) 14.68
The Women's Interagency HIV Study. WIHS Collaborative Study Group. Epidemiology (1998) 12.32
Actin antibody: the specific visualization of actin filaments in non-muscle cells. Proc Natl Acad Sci U S A (1974) 11.64
Increase in salicylic Acid at the onset of systemic acquired resistance in cucumber. Science (1990) 10.47
Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci (2001) 6.66
Simian virus 40 gene A function and maintenance of transformation. J Virol (1975) 6.40
Intermediate filaments: structure, dynamics, function, and disease. Annu Rev Biochem (1994) 6.32
Translation of globin messenger RNA in a heterologous cell-free system. Nature (1971) 6.29
Different intermediate-sized filaments distinguished by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1978) 6.28
Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles. Cell (1985) 6.06
Antibody against tuberlin: the specific visualization of cytoplasmic microtubules in tissue culture cells. Proc Natl Acad Sci U S A (1975) 5.99
Antibody to myosin: the specific visualization of myosin-containing filaments in nonmuscle cells. Proc Natl Acad Sci U S A (1974) 5.93
The complete amino acid sequence of actins from bovine aorta, bovine heart, bovine fast skeletal muscle, and rabbit slow skeletal muscle. A protein-chemical analysis of muscle actin differentiation. Differentiation (1979) 5.90
Testing a tripartite model: I. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales. J Abnorm Psychol (1995) 5.86
Standardized surgery for colonic cancer: complete mesocolic excision and central ligation--technical notes and outcome. Colorectal Dis (2009) 5.72
Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane. Proc Natl Acad Sci U S A (1976) 5.56
At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide. J Mol Biol (1978) 5.34
Grip and pinch strength: normative data for adults. Arch Phys Med Rehabil (1985) 5.34
Amino-terminal sequence analysis of proteins purified on a nanomole scale by gel electrophoresis. J Biol Chem (1972) 5.24
Determinants of HIV-1 shedding in the genital tract of women. Lancet (2001) 5.10
Lac repressor. Specific proteolytic destruction of the NH 2 -terminal region and loss of the deoxyribonucleic acid-binding activity. J Biol Chem (1973) 4.96
Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc Natl Acad Sci U S A (1975) 4.86
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner. Cell (1980) 4.83
Reversible denaturation of enzymes by sodium dodecyl sulfate. J Biol Chem (1971) 4.66
Reliability and validity of grip and pinch strength evaluations. J Hand Surg Am (1984) 4.63
Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates. Exp Cell Res (1979) 4.61
Structurally distinct bacterial luciferases. Biochemistry (1969) 4.03
The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins. EMBO J (1982) 4.01
Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell (1986) 4.01
Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. J Cell Biol (1978) 3.98
Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. J Abnorm Psychol (1995) 3.97
Specific visualization of tubulin-containing structures in tissue culture cells by immunofluorescence. Cytoplasmic microtubules, vinblastine-induced paracrystals, and mitotic figures. Exp Cell Res (1975) 3.95
Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures. J Cell Biol (1980) 3.93
Adult norms for the Box and Block Test of manual dexterity. Am J Occup Ther (1985) 3.92
Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology. Lab Invest (1983) 3.91
MSI and MSII made on ribosome in idling step of protein synthesis. Nature (1972) 3.89
The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol (1988) 3.86
The detertent-resistant cytoskeleton of tissue culture cells includes the nucleus and the microfilament bundles. Exp Cell Res (1977) 3.84
Radioimmunoassay for tubulin: a quantitative comparison of the tubulin content of different established tissue culture cells and tissues. Cell (1978) 3.79
Fractionation of brain microtubule-associated proteins. Isolation of two different proteins which stimulate tubulin polymerization in vitro. Eur J Biochem (1978) 3.62
The distribution of actin in non-muscle cells. The use of actin antibody in the localization of actin within the microfilament bundles of mouse 3T3 cells. Exp Cell Res (1975) 3.59
Desmin is a specific marker for rhabdomyosarcomas of human and rat origin. Am J Pathol (1985) 3.59
Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (Pt K2) by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1977) 3.52
Natural read-through at the UGA termination signal of Q-beta coat protein cistron. Nat New Biol (1971) 3.52
Cytoplasmic microtubular images in glutaraldehyde-fixed tissue culture cells by electron microscopy and by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1978) 3.46
Golgi-derived membranes that contain an acylated viral polypeptide are used for vaccinia virus envelopment. J Virol (1985) 3.44
Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol (1992) 3.43
Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development (1989) 3.37
Diversity of cytokeratins. Differentiation specific expression of cytokeratin polypeptides in epithelial cells and tissues. J Mol Biol (1981) 3.37
The nuclear envelope and the architecture of the nuclear periphery. J Cell Biol (1981) 3.34
Three-dimensional electron microscopical visualization of the cytoskeleton of animal cells: immunoferritin identification of actin- and tubulin-containing structures. Proc Natl Acad Sci U S A (1978) 3.32
Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes. Mol Biol Cell (2000) 3.30
Villin: the major microfilament-associated protein of the intestinal microvillus. Proc Natl Acad Sci U S A (1979) 3.27
A determination of mutagen specificity in bacteria using nonsense mutants of bacteriophage T4. J Mol Biol (1967) 3.26
Structure, biochemistry, and functions of the nuclear envelope. Int Rev Cytol (1974) 3.25
Isolation of amino-terminal fragment of lactose repressor necessary for DNA binding. Biochemistry (1977) 3.22
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Alendronate for the treatment of osteoporosis in men. N Engl J Med (2000) 3.11
Purification of microvilli and an analysis of the protein components of the microfilament core bundle. Exp Cell Res (1978) 3.09
Evaluation of a modified self-report measure of social adjustment. Br J Psychiatry (1982) 3.06
The display of microtubules in transformed cells. Cell (1977) 3.04
Immunofluorescence and immunocytochemical procedures with affinity purified antibodies: tubulin-containing structures. Methods Cell Biol (1982) 2.98
HeLa cells contain intermediate-sized filaments of the prekeratin type. Exp Cell Res (1979) 2.98
Isolation of a set of hybrid lac repressors made in vitro between normal lac repressor and its homogeneous tryptic core. Proc Natl Acad Sci U S A (1976) 2.97
Distribution of actin and tubulin in cells and in glycerinated cell models after treatment with cytochalasin B (CB). Exp Cell Res (1976) 2.96
Immunochemical identification of intermediate-sized filaments in human neoplastic cells. A diagnostic aid for the surgical pathologist. Am J Pathol (1981) 2.94
Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin. Proc Natl Acad Sci U S A (1981) 2.94