Published in Exp Cell Res on October 15, 1978
Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes. Proc Natl Acad Sci U S A (1980) 4.90
Identification and organization of the components in the isolated microvillus cytoskeleton. J Cell Biol (1979) 4.12
Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. J Cell Biol (1978) 3.98
Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures. J Cell Biol (1980) 3.93
Villin: the major microfilament-associated protein of the intestinal microvillus. Proc Natl Acad Sci U S A (1979) 3.27
Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells. J Cell Biol (1983) 3.03
Characterization of an integral membrane glycoprotein associated with the microfilaments of pig intestinal microvilli. EMBO J (1983) 2.95
Immunocytochemical localization of alpha-actinin in intestinal epithelial cells. Proc Natl Acad Sci U S A (1979) 2.86
Regulation of microvillus structure: calcium-dependent solation and cross-linking of actin filaments in the microvilli of intestinal epithelial cells. J Cell Biol (1980) 2.72
Fimbrin is a cytoskeletal protein that crosslinks F-actin in vitro. Proc Natl Acad Sci U S A (1981) 2.56
Brush-border calmodulin. A major component of the isolated microvillus core. J Cell Biol (1980) 2.23
Identification of gelsolin, a Ca2+-dependent regulatory protein of actin gel-sol transformation, and its intracellular distribution in a variety of cells and tissues. J Cell Biol (1981) 2.11
Organization of the actin filament cytoskeleton in the intestinal brush border: a quantitative and qualitative immunoelectron microscope study. J Cell Biol (1988) 1.99
Calcium control of the intestinal microvillus cytoskeleton: its implications for the regulation of microfilament organizations. Proc Natl Acad Sci U S A (1980) 1.92
Localization of myosin, actin, and tropomyosin in rat intestinal epithelium: immunohistochemical studies at the light and electron microscope levels. J Cell Biol (1980) 1.79
Partial reconstruction of the microvillus core bundle: characterization of villin as a Ca++-dependent, actin-bundling/depolymerizing protein. J Cell Biol (1982) 1.77
Isolation and characterization of desmosome-associated tonofilaments from rat intestinal brush border. J Cell Biol (1981) 1.52
Comparison of intestinal brush-border 95-Kdalton polypeptide and alpha-actinins. J Cell Biol (1980) 1.50
High-purity isolation of bullfrog hair bundles and subcellular and topological localization of constituent proteins. J Cell Biol (1991) 1.48
Chicken nonmuscle myosin heavy chains: differential expression of two mRNAs and evidence for two different polypeptides. J Cell Biol (1991) 1.47
Organization of the cross-filaments in intestinal microvilli. J Cell Biol (1982) 1.42
Reassociation of microvillar core proteins: making a microvillar core in vitro. J Cell Biol (1989) 1.40
Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ. J Cell Biol (1994) 1.36
Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin. Proc Natl Acad Sci U S A (1989) 1.34
Calcium-regulated cooperative binding of the microvillar 110K-calmodulin complex to F-actin: formation of decorated filaments. J Cell Biol (1987) 1.33
"Bundle blot" purification and initial protein characterization of hair cell stereocilia. Proc Natl Acad Sci U S A (1989) 1.33
Characterization of intestinal microvillar membrane disks: detergent-resistant membrane sheets enriched in associated brush border myosin I (110K-calmodulin). J Cell Biol (1989) 1.23
Brush-border alpha-actinin? Comparison of two proteins of the microvillus core with alpha-actinin by two-dimensional peptide mapping. J Cell Biol (1980) 1.21
Brush border cytoskeleton and integration of cellular functions. J Cell Biol (1984) 1.19
Tropomyosin distinguishes between the two actin-binding sites of villin and affects actin-binding properties of other brush border proteins. J Cell Biol (1987) 1.15
Isolation and characterization of circumferential microfilament bundles from retinal pigmented epithelial cells. J Cell Biol (1982) 1.13
Radixin is a constituent of stereocilia in hair cells. Proc Natl Acad Sci U S A (2004) 1.13
Microvillus 110K-calmodulin: effects of nucleotides on isolated cytoskeletons and the interaction of the purified complex with F-actin. J Cell Biol (1985) 1.04
The Chlamydomonas mating type plus fertilization tubule, a prototypic cell fusion organelle: isolation, characterization, and in vitro adhesion to mating type minus gametes. J Cell Biol (1997) 0.97
A sialoglycoprotein complex linked to the microvillus cytoskeleton acts as a receptor for pilus (AF/R1) mediated adhesion of enteropathogenic Escherichia coli (RDEC-1) in rabbit small intestine. J Cell Biol (1991) 0.95
Microfilaments and tropomyosin of cultured mammalian cells: isolation and characterization. J Cell Biol (1980) 0.93
Characterization of a 36,000-dalton protein from the surface of Madin-Darby canine kidney cells involved in cell attachment and spreading. J Cell Biol (1985) 0.79
Escherichia coli strain RDEC-1 AF/R1 endogenous fimbrial glycoconjugate receptor molecules in rabbit small intestine. Infect Immun (2001) 0.77
Presence of functional receptors for the Escherichia coli heat-stable enterotoxin in the gastrointestinal tract of the chicken. Infect Immun (1992) 0.75
The reliability of molecular weight determinations by dodecyl sulfate-polyacrylamide gel electrophoresis. J Biol Chem (1969) 142.11
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
Measurement of molecular weights by electrophoresis on SDS-acrylamide gel. Methods Enzymol (1972) 14.68
The Women's Interagency HIV Study. WIHS Collaborative Study Group. Epidemiology (1998) 12.32
Actin antibody: the specific visualization of actin filaments in non-muscle cells. Proc Natl Acad Sci U S A (1974) 11.64
Polarization of cell growth in yeast. J Cell Sci (2000) 7.23
Identification of essential genes in cultured mammalian cells using small interfering RNAs. J Cell Sci (2001) 6.66
Simian virus 40 gene A function and maintenance of transformation. J Virol (1975) 6.40
Intermediate filaments: structure, dynamics, function, and disease. Annu Rev Biochem (1994) 6.32
Different intermediate-sized filaments distinguished by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1978) 6.28
Antibody against tuberlin: the specific visualization of cytoplasmic microtubules in tissue culture cells. Proc Natl Acad Sci U S A (1975) 5.99
Antibody to myosin: the specific visualization of myosin-containing filaments in nonmuscle cells. Proc Natl Acad Sci U S A (1974) 5.93
The complete amino acid sequence of actins from bovine aorta, bovine heart, bovine fast skeletal muscle, and rabbit slow skeletal muscle. A protein-chemical analysis of muscle actin differentiation. Differentiation (1979) 5.90
Testing a tripartite model: I. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales. J Abnorm Psychol (1995) 5.86
Standardized surgery for colonic cancer: complete mesocolic excision and central ligation--technical notes and outcome. Colorectal Dis (2009) 5.72
Cytoplasmic microtubules in tissue culture cells appear to grow from an organizing structure towards the plasma membrane. Proc Natl Acad Sci U S A (1976) 5.56
At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide. J Mol Biol (1978) 5.34
Grip and pinch strength: normative data for adults. Arch Phys Med Rehabil (1985) 5.34
Amino-terminal sequence analysis of proteins purified on a nanomole scale by gel electrophoresis. J Biol Chem (1972) 5.24
Determinants of HIV-1 shedding in the genital tract of women. Lancet (2001) 5.10
Lac repressor. Specific proteolytic destruction of the NH 2 -terminal region and loss of the deoxyribonucleic acid-binding activity. J Biol Chem (1973) 4.96
Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc Natl Acad Sci U S A (1975) 4.86
Villin is a major protein of the microvillus cytoskeleton which binds both G and F actin in a calcium-dependent manner. Cell (1980) 4.83
Reversible denaturation of enzymes by sodium dodecyl sulfate. J Biol Chem (1971) 4.66
Reliability and validity of grip and pinch strength evaluations. J Hand Surg Am (1984) 4.63
Widespread occurrence of intermediate-sized filaments of the vimentin-type in cultured cells from diverse vertebrates. Exp Cell Res (1979) 4.61
Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family. J Cell Biol (1997) 4.32
Structurally distinct bacterial luciferases. Biochemistry (1969) 4.03
The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins. EMBO J (1982) 4.01
Antibody to prekeratin. Decoration of tonofilament like arrays in various cells of epithelial character. Exp Cell Res (1978) 4.01
Localization of actin and microfilament-associated proteins in the microvilli and terminal web of the intestinal brush border by immunofluorescence microscopy. J Cell Biol (1978) 3.98
Testing a tripartite model: II. Exploring the symptom structure of anxiety and depression in student, adult, and patient samples. J Abnorm Psychol (1995) 3.97
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the beta2-adrenergic receptor. Nature (1999) 3.95
Specific visualization of tubulin-containing structures in tissue culture cells by immunofluorescence. Cytoplasmic microtubules, vinblastine-induced paracrystals, and mitotic figures. Exp Cell Res (1975) 3.95
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain. Cell (2000) 3.94
Fimbrin, a new microfilament-associated protein present in microvilli and other cell surface structures. J Cell Biol (1980) 3.93
Adult norms for the Box and Block Test of manual dexterity. Am J Occup Ther (1985) 3.92
Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology. Lab Invest (1983) 3.91
MSI and MSII made on ribosome in idling step of protein synthesis. Nature (1972) 3.89
Tropomyosin-containing actin cables direct the Myo2p-dependent polarized delivery of secretory vesicles in budding yeast. J Cell Biol (1998) 3.89
The organization of titin filaments in the half-sarcomere revealed by monoclonal antibodies in immunoelectron microscopy: a map of ten nonrepetitive epitopes starting at the Z line extends close to the M line. J Cell Biol (1988) 3.86
Construction of a GAL1-regulated yeast cDNA expression library and its application to the identification of genes whose overexpression causes lethality in yeast. Genetics (1992) 3.86
The detertent-resistant cytoskeleton of tissue culture cells includes the nucleus and the microfilament bundles. Exp Cell Res (1977) 3.84
Radioimmunoassay for tubulin: a quantitative comparison of the tubulin content of different established tissue culture cells and tissues. Cell (1978) 3.79
Polarization of cell growth in yeast. I. Establishment and maintenance of polarity states. J Cell Sci (2000) 3.73
Disruption of the single tropomyosin gene in yeast results in the disappearance of actin cables from the cytoskeleton. Cell (1989) 3.62
Fractionation of brain microtubule-associated proteins. Isolation of two different proteins which stimulate tubulin polymerization in vitro. Eur J Biochem (1978) 3.62
Desmin is a specific marker for rhabdomyosarcomas of human and rat origin. Am J Pathol (1985) 3.59
The distribution of actin in non-muscle cells. The use of actin antibody in the localization of actin within the microfilament bundles of mouse 3T3 cells. Exp Cell Res (1975) 3.59
Visualization of a system of filaments 7-10 nm thick in cultured cells of an epithelioid line (Pt K2) by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1977) 3.52
Natural read-through at the UGA termination signal of Q-beta coat protein cistron. Nat New Biol (1971) 3.52
Cytoplasmic microtubular images in glutaraldehyde-fixed tissue culture cells by electron microscopy and by immunofluorescence microscopy. Proc Natl Acad Sci U S A (1978) 3.46
Golgi-derived membranes that contain an acylated viral polypeptide are used for vaccinia virus envelopment. J Virol (1985) 3.44
Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development (1989) 3.37
Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site. Mol Biol Cell (1995) 3.36
Three-dimensional electron microscopical visualization of the cytoskeleton of animal cells: immunoferritin identification of actin- and tubulin-containing structures. Proc Natl Acad Sci U S A (1978) 3.32
Essential roles for Caenorhabditis elegans lamin gene in nuclear organization, cell cycle progression, and spatial organization of nuclear pore complexes. Mol Biol Cell (2000) 3.30
Villin: the major microfilament-associated protein of the intestinal microvillus. Proc Natl Acad Sci U S A (1979) 3.27
The FERM domain: a unique module involved in the linkage of cytoplasmic proteins to the membrane. Trends Biochem Sci (1998) 3.24
Isolation of amino-terminal fragment of lactose repressor necessary for DNA binding. Biochemistry (1977) 3.22
Myosin V orientates the mitotic spindle in yeast. Nature (2000) 3.20
Incidence of vertebral fracture in europe: results from the European Prospective Osteoporosis Study (EPOS). J Bone Miner Res (2002) 3.16
Alendronate for the treatment of osteoporosis in men. N Engl J Med (2000) 3.11
cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1. EMBO J (1989) 3.10
The display of microtubules in transformed cells. Cell (1977) 3.04
Purification of an 80,000-dalton protein that is a component of the isolated microvillus cytoskeleton, and its localization in nonmuscle cells. J Cell Biol (1983) 3.03
Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cells. J Cell Sci (1993) 3.02
Immunofluorescence and immunocytochemical procedures with affinity purified antibodies: tubulin-containing structures. Methods Cell Biol (1982) 2.98
HeLa cells contain intermediate-sized filaments of the prekeratin type. Exp Cell Res (1979) 2.98
Isolation of a set of hybrid lac repressors made in vitro between normal lac repressor and its homogeneous tryptic core. Proc Natl Acad Sci U S A (1976) 2.97
Distribution of actin and tubulin in cells and in glycerinated cell models after treatment with cytochalasin B (CB). Exp Cell Res (1976) 2.96
Vascular smooth muscle cells differ from other smooth muscle cells: predominance of vimentin filaments and a specific alpha-type actin. Proc Natl Acad Sci U S A (1981) 2.94
Cell-to-substratum contacts in living cells: a direct correlation between interference-reflexion and indirect-immunofluorescence microscopy using antibodies against actin and alpha-actinin. J Cell Sci (1979) 2.93
Parallel secretory pathways to the cell surface in yeast. J Cell Biol (1995) 2.92
An F-actin- and calmodulin-binding protein from isolated intestinal brush borders has a morphology related to spectrin. Cell (1982) 2.89
Bacteriophage Q replicase contains the protein biosynthesis elongation factors EF Tu and EF Ts. Proc Natl Acad Sci U S A (1972) 2.88
The COOH-terminal domain of Myo2p, a yeast myosin V, has a direct role in secretory vesicle targeting. J Cell Biol (1999) 2.84
Mammalian cytoplasmic actins are the products of at least two genes and differ in primary structure in at least 25 identified positions from skeletal muscle actins. Proc Natl Acad Sci U S A (1978) 2.84
New structural model of E. coli aspartate transcarbamylase and the amino-acid sequence of the regulatory polypeptide chain. Nature (1968) 2.81
An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton. J Biol Chem (1998) 2.80
Phalloidin-induced actin polymerization in the cytoplasm of cultured cells interferes with cell locomotion and growth. Proc Natl Acad Sci U S A (1977) 2.77
Retention of women enrolled in a prospective study of human immunodeficiency virus infection: impact of race, unstable housing, and use of human immunodeficiency virus therapy. Am J Epidemiol (2001) 2.77
Characterization of TPM1 disrupted yeast cells indicates an involvement of tropomyosin in directed vesicular transport. J Cell Biol (1992) 2.76
F-actin binding and bundling properties of fimbrin, a major cytoskeletal protein of microvillus core filaments. J Biol Chem (1981) 2.72
Proteinchemical characterization of three structurally distinct domains along the protofilament unit of desmin 10 nm filaments. Cell (1982) 2.67
Neurofilament architecture combines structural principles of intermediate filaments with carboxy-terminal extensions increasing in size between triplet proteins. EMBO J (1983) 2.64
Erythroid spectrin, brain fodrin, and intestinal brush border proteins (TW-260/240) are related molecules containing a common calmodulin-binding subunit bound to a variant cell type-specific subunit. Proc Natl Acad Sci U S A (1982) 2.63
The protein-tyrosine kinase substrate, p81, is homologous to a chicken microvillar core protein. J Cell Biol (1986) 2.63
Intermediate filaments. Cold Spring Harb Symp Quant Biol (1982) 2.61
Griseofulvin interacts with microtubules both in vivo and in vitro. J Mol Biol (1976) 2.61
Coexpression of a mutant beta-actin and the two normal beta- and gamma-cytoplasmic actins in a stably transformed human cell line. Cell (1980) 2.58
Fimbrin is a cytoskeletal protein that crosslinks F-actin in vitro. Proc Natl Acad Sci U S A (1981) 2.56
Intermediate-sized filaments of the prekeratin type in myoepithelial cells. J Cell Biol (1980) 2.54
Translational restarts: AUG reinitiation of a lac repressor fragment. Proc Natl Acad Sci U S A (1972) 2.45
Structure and biochemistry of mouse hepatic gap junctions. J Mol Biol (1979) 2.44