Published in Anal Biochem on May 15, 1987
Ectoenzymes of the kidney microvillar membrane. Affinity purification, characterization and localization of the phospholipase C-solubilized form of renal dipeptidase. Biochem J (1989) 1.37
In vitro activity of BMS-181139, a new carbapenem with potent antipseudomonal activity. Antimicrob Agents Chemother (1995) 0.87
Epidemiology of sepsis and multiple organ dysfunction syndrome in children. Chest (1996) 1.96
Affinity of cephalosporins for beta-lactamases as a factor in antibacterial efficacy. Antimicrob Agents Chemother (1986) 1.95
Leukotriene B4 plays a critical role in the progression of collagen-induced arthritis. Proc Natl Acad Sci U S A (1995) 1.85
Timing and predictors of death in pediatric patients with multiple organ system failure. Crit Care Med (1994) 1.84
Cellular pharmacology of 2',3'-dideoxy-2',3'-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus. Antimicrob Agents Chemother (1989) 1.66
Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine. Mol Pharmacol (1992) 1.65
Use of in vitro topoisomerase II assays for studying quinolone antibacterial agents. Antimicrob Agents Chemother (1989) 1.51
1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo. Antimicrob Agents Chemother (1994) 1.39
Clinical pharmacokinetics of cidofovir in human immunodeficiency virus-infected patients. Antimicrob Agents Chemother (1995) 1.32
Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3). Biochem Biophys Res Commun (1991) 1.28
Detection of caspases activation by fluorochrome-labeled inhibitors: Multiparameter analysis by laser scanning cytometry. Cytometry (2001) 1.27
In vitro and in vivo disposition and metabolism of 3'-deoxy-2',3'-didehydrothymidine. Antimicrob Agents Chemother (1993) 1.23
Synthesis and in vitro evaluation of a phosphonate prodrug: bis(pivaloyloxymethyl) 9-(2-phosphonylmethoxyethyl)adenine. Antiviral Res (1992) 1.20
High-frequency fusion of Streptomyces parvulus or Streptomyces antibioticus protoplasts induced by polyethylene glycol. J Bacteriol (1979) 1.19
Evaluation of infrequent dosing regimens with (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]-cytosine (S-HPMPC) on simian varicella infection in monkeys. Antiviral Res (1991) 1.17
Pharmacokinetics of cidofovir in monkeys. Evidence for a prolonged elimination phase representing phosphorylated drug. Drug Metab Dispos (1996) 1.17
Biochemical pharmacology of acyclic nucleotide analogues. Ann N Y Acad Sci (1990) 1.17
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent. J Med Chem (1989) 1.17
Detection of caspase activation in situ by fluorochrome-labeled caspase inhibitors. Biotechniques (2001) 1.12
Synthesis and antiviral activity of the nucleotide analogue (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine. J Med Chem (1989) 1.10
Effect of oral probenecid coadministration on the chronic toxicity and pharmacokinetics of intravenous cidofovir in cynomolgus monkeys. Toxicol Sci (1998) 1.09
Clinically significant upper gastrointestinal bleeding acquired in a pediatric intensive care unit: a prospective study. Pediatrics (1998) 1.05
Susceptibility of human cytomegalovirus to cidofovir is unchanged after limited in vivo exposure to various regimens of drug. J Infect Dis (1996) 1.04
The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696. J Pharmacol Exp Ther (1995) 1.03
Cellular pharmacology of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) in human peripheral blood mononuclear cells. Biochem Pharmacol (1990) 1.01
Frequency of upper gastrointestinal bleeding in a pediatric intensive care unit. Crit Care Med (1992) 0.99
(S)-1-(3-hydroxy-2-(phosphonylmethoxy)propyl)cytosine (HPMPC): a potent antiherpesvirus agent. Adv Exp Med Biol (1990) 0.98
Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine. J Med Chem (1992) 0.97
Actinomycin biosynthesis by protoplasts derived from Streptomyces parvulus. Antimicrob Agents Chemother (1978) 0.97
Ribavirin in ventilated respiratory syncytial virus bronchiolitis. A randomized, placebo-controlled trial. Am J Respir Crit Care Med (1999) 0.95
Admissions to a pediatric intensive care unit for status epilepticus: a 10-year experience. Crit Care Med (1994) 0.95
Synthesis, oral bioavailability determination, and in vitro evaluation of prodrugs of the antiviral agent 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). J Med Chem (1994) 0.93
Distinct kynureninase and hydroxykynureninase enzymes in an actinomycin-producing strain of Streptomyces parvulus. Biochim Biophys Acta (1980) 0.93
Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits. Curr Eye Res (1996) 0.91
Comparison of in vitro biological properties and mouse toxicities of three thymidine analogs active against human immunodeficiency virus. Antimicrob Agents Chemother (1990) 0.90
Preparation of oocytes for microinjection of RNA and DNA. Methods Enzymol (1987) 0.90
Preparation of interferon messenger RNAs with the use of ribonucleoside--vanadyl complexes. Methods Enzymol (1981) 0.90
Metabolism and DNA interaction of 2',3'-didehydro-2',3'-dideoxythymidine in human bone marrow cells. Mol Pharmacol (1991) 0.89
Characterization of interferon messenger RNA synthesis in Namalva cells. J Biol Chem (1980) 0.89
Evidence for a constitutive and inducible form of kynurenine formamidase in an actinomycin-producing strain of Streptomyces parvulus. Arch Biochem Biophys (1980) 0.88
Uvulitis and supraglottitis: early manifestations of Kawasaki disease. J Pediatr (1992) 0.88
Decision making and end-of-life care in critically ill children. J Palliat Care (2000) 0.87
Evidence for two acyl group conformations in some furylacryloyl- and thienylacryloylchymotrypsins: resonance Raman studies of enzyme--substrate intermediates at pH 3.0. Biochemistry (1981) 0.87
Acyclic purine phosphonate analogues as antiviral agents. Synthesis and structure-activity relationships. J Med Chem (1990) 0.87
Regulation of lysine- and lysine-plus-threonine-inhibitable aspartokinases in Bacillus brevis. J Bacteriol (1980) 0.86
Synthesis and in vitro activity of C-2 quaternary heterocyclic alkylthio carbapenems. J Antibiot (Tokyo) (1987) 0.86
Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1. Cell Signal (1997) 0.84
Resonance Raman-spectroscopic studies of the hapten features involved in the binding of 2,4-dinitrophenyl haptens by the mouse myeloma proteins MOPC 315 and MOPC 460. Biochem J (1978) 0.84
Purification and characterization of kynurenine formamidase activities from Streptomyces parvulus. Can J Microbiol (1986) 0.83
Phosphonomethylether compounds as antiviral agents. Transplant Proc (1991) 0.83
Correlations between reactivity and structure of some chromophoric acylchymotrypsins by resonance Raman spectroscopy. Biochemistry (1981) 0.83
Nosocomial pneumonia and tracheitis in a pediatric intensive care unit: a prospective study. Am J Respir Crit Care Med (1997) 0.82
Comparative studies of 2',3'-didehydro-2',3'-dideoxythymidine (D4T) with other pyrimidine nucleoside analogues. Ann N Y Acad Sci (1990) 0.81
Stathmo-apoptosis: arresting apoptosis by fluorochrome-labeled inhibitor of caspases. Int J Oncol (2001) 0.80
Anti-MRSA cephems. Part 1: C-3 substituted thiopyridinium derivatives. Bioorg Med Chem Lett (2001) 0.80
Microinjection into Xenopus oocytes: equipment. Methods Enzymol (1987) 0.80
Sid4: A secreted vertebrate immunoglobulin protein with roles in zebrafish embryogenesis. Dev Biol (2005) 0.80
Diabetes insipidus in a quadriplegic patient. Arch Phys Med Rehabil (1986) 0.80
Effect of cephalosporins on organic ion transport in renal membrane vesicles from rat and rabbit kidney cortex. Res Commun Chem Pathol Pharmacol (1985) 0.80
Phase II study of elsamitrucin (BMY-28090) for the treatment of patients with refractory/relapsed non-Hodgkin's lymphoma. Invest New Drugs (1996) 0.80
Translation of human immune interferon messenger RNA in Xenopus laevis oocytes. Biochem Biophys Res Commun (1981) 0.79
Synthesis and antiviral activity of 2'-substituted 9-[2-(phosphonomethoxy)ethyl]guanine analogues. J Med Chem (1993) 0.78
Charge effects in the active site of papain: resonance Raman and absorption evidence for electron polarization occurring in the acyl group of some acylpapains. Biochemistry (1978) 0.77
A preclinical and clinical overview of the nucleotide-based antiviral agent cidofovir (HPMPC). Adv Exp Med Biol (1996) 0.77
Arylformamidase from Streptomyces parvulus. Methods Enzymol (1987) 0.77
Microinjection of Xenopus oocytes. An automated device for volume control in the nanoliter range. Anal Biochem (1980) 0.77
Naloxone for shock. Cochrane Database Syst Rev (2003) 0.77
Octopamine modulates photoreceptor function in the Limulus lateral eye. Vis Neurosci (1989) 0.76
Resonance Raman and electronic absorption spectral studies of some beta-(2-furyl)acryloylglyceraldehyde-3-phosphate dehydrogenases. Biochemistry (1981) 0.76
Biaryl diacid inhibitors of human s-PLA2 with anti-inflammatory activity. Bioorg Med Chem (2000) 0.76
Convulsions and hypertension in children: differentiating cause from effect. Crit Care Med (1993) 0.76
Radiolabeled quaternary carbapenems and their interactions with human serum albumin. Antimicrob Agents Chemother (1988) 0.75
Food service: more training programs recommended. Hospitals (1973) 0.75
Chilled food systems. Effects of chilled holding on quality of beef loaves. J Am Diet Assoc (1975) 0.75
Hypertensive iridocyclitis associated with meningococcal infection. Crit Care Med (1992) 0.75
A new class of acyclic phosphonate nucleotide analogues: phosphonate isosteres of acyclovir and ganciclovir monophosphates as antiviral agents. J Med Chem (1991) 0.75
Cellular metabolism and enzymatic phosphorylation of 9-(2-phosphonylmethoxyethyl) guanine (PMEG), a potent antiviral agent. Adv Exp Med Biol (1992) 0.75
Inadvertent pericardiacophrenic vein catheterization. Chest (1992) 0.75
Synthesis and antiviral activity of (S)-9-[4-hydroxy-3-(phosphonomethoxy)butyl]guanine. J Med Chem (1990) 0.75
Synthesis and in vitro activity of 1 beta-methyl C-2 quaternary heterocyclic alkylthio carbapenems. J Med Chem (1989) 0.75
Cilastatin-sensitive dehydropeptidase I enzymes from three sources all catalyze carbapenem hydrolysis and conversion of leukotriene D4 to leukotriene E4. Arch Biochem Biophys (1987) 0.75
Prodrugs of 2',3'-didehydro-3'-deoxythymidine (D4T): synthesis, antiviral activity, and rapid pharmacokinetic evaluation. J Pharm Sci (1994) 0.75
Blood lactate and gastric intramucosal pH during severe sepsis. Crit Care Med (1996) 0.75
A new approach to the limiting dilution assay. J Biopharm Stat (1994) 0.75
The lack of allylic oxidation in the Moffatt oxidation. Preparation of 5 -lanost-8-en-3-one. Steroids (1972) 0.75
[Prophylaxis of gastroduodenal hemorrhage caused by stress during pediatric intensive care]. Pediatrie (1991) 0.75
Increased capacity for RNA synthesis in Dictyostelium discoideum nuclei induced by exposure to cyclic AMP or 5'-AMP. Biochem Biophys Res Commun (1973) 0.75
Separation of dinitrophenyl derivatives of neutral dipeptides by thin-layer chromatography. J Chromatogr (1975) 0.75
C5a as a model for chemotactic factor-stimulated tyrosine phosphorylation in the human neutrophil. J Immunol (1994) 0.75
Therapy of shock with naloxone: a meta-analysis. Crit Care Med (1998) 0.75
trans-3-Benzyl-4-hydroxy-7-chromanylbenzoic acid derivatives as antagonists of the leukotriene B4 (LTB4) receptor. Bioorg Med Chem Lett (1998) 0.75
Effect of holding on broccoli prepared in volume. J Am Diet Assoc (1966) 0.75
Personnel training needs. Hospitals (1971) 0.75
Synthesis of chromophoric dehydro analog of leucine enkephalin. Int J Pept Protein Res (1981) 0.75