Isolation of genomic DNA.

Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene. Mol Cell Biol (1997) 2.16

Detection of Candida albicans and other yeasts in blood by PCR. J Clin Microbiol (1994) 2.13

Fibulin-4: a novel gene for an autosomal recessive cutis laxa syndrome. Am J Hum Genet (2006) 1.99

Interleukin 1 receptor antagonist is a member of the interleukin 1 gene family: evolution of a cytokine control mechanism. Proc Natl Acad Sci U S A (1991) 1.97

Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells. PLoS One (2009) 1.94

Molecular mechanism of slow acetylation of drugs and carcinogens in humans. Proc Natl Acad Sci U S A (1991) 1.91

Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP. EMBO J (1995) 1.88

Molecular structure and functional characterization of a human complement cytolysis inhibitor found in blood and seminal plasma: identity to sulfated glycoprotein 2, a constituent of rat testis fluid. Proc Natl Acad Sci U S A (1989) 1.85

Overexpression of the cellular retinoic acid binding protein-I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma cells. J Cell Biol (1991) 1.58

Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers. PLoS Med (2007) 1.52

A yeast artificial chromosome telomere clone spanning a possible location of the Huntington disease gene. Am J Hum Genet (1990) 1.41

Retracted Aberrant methylation of SPARC in human lung cancers. Br J Cancer (2005) 1.40

Loss-of-function mutations in ATP6V0A2 impair vesicular trafficking, tropoelastin secretion and cell survival. Hum Mol Genet (2009) 1.40

Aortic aneurysmal disease and cutis laxa caused by defects in the elastin gene. J Med Genet (2005) 1.40

N-acetylation pharmacogenetics: a gene deletion causes absence of arylamine N-acetyltransferase in liver of slow acetylator rabbits. Proc Natl Acad Sci U S A (1989) 1.39

Detection of Toxoplasma gondii in venous blood from AIDS patients by polymerase chain reaction. J Clin Microbiol (1993) 1.35

Spider minor ampullate silk proteins contain new repetitive sequences and highly conserved non-silk-like "spacer regions". Protein Sci (1998) 1.34

In vitro CD4+ lymphocyte transformation and infection in a rabbit model with a molecular clone of human T-cell lymphotrophic virus type 1. J Virol (1996) 1.33

Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase. Am J Hum Genet (1991) 1.32

Sequential molecular changes during multistage pathogenesis of small peripheral adenocarcinomas of the lung. J Thorac Oncol (2008) 1.30

Construction of a NotI linking library and isolation of new markers close to the Huntington's disease gene. Nucleic Acids Res (1988) 1.24

Regulation of IMP dehydrogenase gene expression by its end products, guanine nucleotides. Mol Cell Biol (1991) 1.15

Control of partial digestion combining the enzymes dam methylase and MboI. Nucleic Acids Res (1989) 1.14

Global population genetic structure and male-mediated gene flow in the green turtle (Chelonia mydas): RFLP analyses of anonymous nuclear loci. Genetics (1992) 1.11

Regulation of intestinal lactase in adult hypolactasia. J Clin Invest (1992) 1.11

cDNA sequence of a second fibrinogen alpha chain in lamprey: an archetypal version alignable with full-length beta and gamma chains. Proc Natl Acad Sci U S A (1992) 1.08

Differential expression of the two human arginase genes in hyperargininemia. Enzymatic, pathologic, and molecular analysis. J Clin Invest (1989) 1.06

Localization of DNA sequences to a region within Xp11.21 between incontinentia pigmenti (IP1) X-chromosomal translocation breakpoints. Am J Hum Genet (1991) 1.06

Testis-specific transcription initiation sites of rat farnesyl pyrophosphate synthetase mRNA. Mol Cell Biol (1990) 1.00

Establishment and validation of real-time polymerase chain reaction method for CDH1 promoter methylation. Am J Pathol (2002) 0.99

The alpha 1 (IX) collagen gene gives rise to two different transcripts in both mouse embryonic and human fetal RNA. Proc Natl Acad Sci U S A (1990) 0.94

A simple and sensitive method for determining transcription initiation site: identification of two transcription initiation sites in rat group II phospholipase A2 gene. Nucleic Acids Res (1990) 0.93

A rapid method for the isolation of genomic DNA from citrated whole blood. Biochem J (1991) 0.91

Elucidation of a promoter activity that directs the expression of acetyl-CoA carboxylase alpha with an alternative N-terminus in a tissue-restricted fashion. Biochem J (1998) 0.89

A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. EMBO J (1992) 0.87

Impact of aberrant methylation of microRNA-9 family members on non-small cell lung cancers. Mol Clin Oncol (2012) 0.87

Hybridization-based mapping of Neurospora crassa linkage groups II and V. Genetics (2001) 0.86

An improved non-enzymatic "DNA ladder assay" for more sensitive and early detection of apoptosis. Cytotechnology (2011) 0.86

Fine mapping of the McLeod locus (XK) to a 150-380-kb region in Xp21. Am J Hum Genet (1992) 0.83

Rearrangements of the tal-1 locus as clonal markers for T cell acute lymphoblastic leukemia. J Clin Invest (1991) 0.83

Saturating the region of the polycystic kidney disease gene with NotI linking clones. Am J Hum Genet (1991) 0.82

Quantitative Southern blot analysis in the dystrophin gene of Japanese patients with Duchenne or Becker muscular dystrophy: a high frequency of duplications. J Med Genet (1992) 0.81

Anti-tumor effect of bisphosphonate (YM529) on non-small cell lung cancer cell lines. BMC Cancer (2007) 0.80

Identification of carriers of Duchenne/Becker muscular dystrophy by a novel method based on detection of junction fragments in the dystrophin gene. J Med Genet (1996) 0.80

Identification and characterization of orthologs of AtNHX5 and AtNHX6 in Brassica napus. Front Plant Sci (2012) 0.79

Ornithine transcarbamylase deficiency combined with type 1 diabetes mellitus - a challenge in clinical and dietary management. J Diabetes Metab Disord (2013) 0.79

Glutamate and synaptic plasticity systems and smoking behavior: results from a genetic association study. PLoS One (2012) 0.77

Molecular genetic study of human arginase deficiency. Am J Hum Genet (1992) 0.77

Overexpression and biosynthesis of CD4 in Chinese hamster ovary cells: coamplification using the multiple drug resistance gene. Proc Natl Acad Sci U S A (1989) 0.76

Production of human apolipoprotein(a) transgenic NIBS miniature pigs by somatic cell nuclear transfer. Exp Anim (2015) 0.75

A new detection method for the K variant of butyrylcholinesterase based on PCR primer introduced restriction analysis (PCR-PIRA). J Med Genet (1994) 0.75

Estimation of age-related DNA degradation from formalin-fixed and paraffin-embedded tissue according to the extraction methods. Exp Ther Med (2017) 0.75

Lambda replacement vectors carrying polylinker sequences. J Mol Biol (1983) 32.76

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature (1990) 10.97

Nucleotide sequence of cdna coding for Semliki Forest virus membrane glycoproteins. Nature (1980) 8.07

Rapid restriction mapping of DNA cloned in lambda phage vectors. Gene (1984) 6.25

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech Dev (1996) 5.13

Expression pattern of the mouse T gene and its role in mesoderm formation. Nature (1990) 4.97

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein. Nat Genet (1996) 4.59

Selective isolation of cosmid clones by homologous recombination in Escherichia coli. Proc Natl Acad Sci U S A (1984) 4.11

A subcloning strategy for DNA sequence analysis. Nucleic Acids Res (1980) 4.06

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus. Nature (1991) 3.48

Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell (1991) 3.40

Construction and characterization of a 2.5-kilobase procollagen clone. Proc Natl Acad Sci U S A (1978) 3.26

The capsid protein of Semliki Forest virus has clusters of basic amino acids and prolines in its amino-terminal region. Proc Natl Acad Sci U S A (1980) 3.26

Covalent attachment of DNA to agarose. Improved synthesis and use in affinity chromatography. Eur J Biochem (1975) 3.18

A large inverted duplication allows homologous recombination between chromosomes heterozygous for the proximal t complex inversion. Cell (1987) 2.88

The protein product of the zebrafish homologue of the mouse T gene is expressed in nuclei of the germ ring and the notochord of the early embryo. Development (1992) 2.76

Skeletal muscle actin mRNA. Characterization of the 3' untranslated region. Nucleic Acids Res (1981) 2.67

CpG island clones from a deletion encompassing the gene for adenomatous polyposis coli. Proc Natl Acad Sci U S A (1989) 2.66

Construction and use of human chromosome jumping libraries from NotI-digested DNA. Nature (1987) 2.58

Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes. Cell (1984) 2.55

Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the alpha globin cluster. Hum Mol Genet (2001) 2.46

Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes. Cell (1986) 2.40

Procollagen complementary DNA, a probe for messenger RNA purification and the number of type I collagen genes. Biochemistry (1978) 2.37

Huntington disease-linked locus D4S111 exposed as the alpha-L-iduronidase gene. Somat Cell Mol Genet (1991) 2.23

Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor. Nature (1997) 2.20

Construction of recombinant plasmids containing rat muscle actin and myosin light chain DNA sequences. Proc Natl Acad Sci U S A (1980) 2.17

Construction and characterization of pro alpha 1 collagen complementary deoxyribonucleic acid clones. Biochemistry (1979) 2.08

Molecular approaches to mammalian genetics. Cold Spring Harb Symp Quant Biol (1986) 1.99

The Brachyury gene encodes a novel DNA binding protein. EMBO J (1993) 1.94

Brachyury is a target gene of the Wnt/beta-catenin signaling pathway. Mech Dev (2000) 1.91

The T protein encoded by Brachyury is a tissue-specific transcription factor. EMBO J (1995) 1.89

Molecular probes define different regions of the mouse t complex. Cell (1985) 1.65

Immunohistochemical analysis of the Brachyury protein in wild-type and mutant mouse embryos. Dev Biol (1994) 1.63

Construction and characterization of a genomic library in lambda. Methods Enzymol (1987) 1.60

Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev (2000) 1.47

Homologs of the mouse Brachyury gene are involved in the specification of posterior terminal structures in Drosophila, Tribolium, and Locusta. Genes Dev (1994) 1.46

Brain tubulin and actin cDNA sequences: isolation of recombinant plasmids. Nucleic Acids Res (1980) 1.35

Lambda phage vectors--EMBL series. Methods Enzymol (1987) 1.28

Molecular evidence for the rapid propagation of mouse t haplotypes from a single, recent, ancestral chromosome. Mol Biol Evol (1987) 1.27

Detection of messenger RNA by in situ hybridization to postimplantation embryo whole mounts. Methods Enzymol (1993) 1.24

The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster. Genomics (1998) 1.24

A contig of non-chimaeric YACs containing the spinal muscular atrophy gene in 5q13. Hum Mol Genet (1993) 1.23

Distribution and developmentally regulated expression of murine polycystin. Am J Physiol (1997) 1.23

Rescue of the tail defect of Brachyury mice. Genes Dev (1993) 1.22

Germline mutations of the CDKN2 gene in UK melanoma families. Hum Mol Genet (1997) 1.19

Deletion and duplication of DNA sequences is associated with the embryonic lethal phenotype of the t9 complementation group of the mouse t complex. Genes Dev (1987) 1.19

The paired homeobox gene Uncx4.1 specifies pedicles, transverse processes and proximal ribs of the vertebral column. Development (2000) 1.17

Isolation and translation of calvaria procollagen messenger ribonucleic acids. Biochemistry (1976) 1.17

The pseudoautosomal boundary in man is defined by an Alu repeat sequence inserted on the Y chromosome. Nature (1989) 1.17

A family of cosmid vectors with the multi-copy R6K replication origin. Gene (1987) 1.16

Genomic organization of M line titin and its tissue-specific expression in two distinct isoforms. J Mol Biol (1996) 1.16

A cell autonomous function of Brachyury in T/T embryonic stem cell chimaeras. Nature (1991) 1.14

Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mech Dev (1996) 1.13

Nucleotide sequence of cloned cDNA coding for honeybee prepromelittin. Eur J Biochem (1983) 1.12

The gene for autosomal dominant polycystic kidney disease lies in a 750-kb CpG-rich region. Genomics (1992) 1.12

Rubinstein-Taybi syndrome caused by submicroscopic deletions within 16p13.3. Am J Hum Genet (1993) 1.12

Conservation of Brachyury (T) genes in amphioxus and vertebrates: developmental and evolutionary implications. Development (1995) 1.12

A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae. Development (1993) 1.07

Cooperation between GLI and JUN enhances transcription of JUN and selected GLI target genes. Oncogene (2009) 1.06

PHF2, a novel PHD finger gene located on human chromosome 9q22. Mamm Genome (1999) 1.04

Digestion of DNA: size fractionation. Methods Enzymol (1987) 1.03

Construction and characterization of type II collagen complementary deoxyribonucleic acid clones. Nucleic Acids Res (1983) 1.03

The chick Brachyury gene: developmental expression pattern and response to axial induction by localized activin. Dev Biol (1995) 1.01

Large-scale screen for genes involved in gonad development. Mech Dev (2000) 1.00

Affinity labeling of E. coli RNA polymerase with substrate and template analogues. Biochem Biophys Res Commun (1973) 0.96

A new DNA marker (D4S90) is located terminally on the short arm of chromosome 4, close to the Huntington disease gene. Genomics (1989) 0.94

Expression and characterization of soluble and membrane-bound human nucleoside triphosphate diphosphohydrolase 6 (CD39L2). J Biol Chem (2000) 0.93

Genetic heterogeneity in familial malignant melanoma. Hum Mol Genet (1994) 0.92

Isolation and characterization of cDNA clones from mouse skeletal muscle actin mRNA. DNA (1986) 0.91

FKHL15, a new human member of the forkhead gene family located on chromosome 9q22. Genomics (1997) 0.90

Construction of a map of chromosome 16 by using radiation hybrids. Proc Natl Acad Sci U S A (1992) 0.89

Characterization of a widely expressed gene (LUC7-LIKE; LUC7L) defining the centromeric boundary of the human alpha-globin domain. Genomics (2001) 0.88

Analysis of gene expression using high-density and IFN-gamma-specific low-density cDNA arrays. Genomics (2001) 0.87

Kidney-specific cadherin (cdh16) is expressed in embryonic kidney, lung, and sex ducts. Mech Dev (1999) 0.87

Expression and differential splicing of the mouse TSC2 homolog. Mamm Genome (1996) 0.86

Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium. Development (2001) 0.86

The mouse homolog of PKD1: sequence analysis and alternative splicing. Mamm Genome (1997) 0.83

Molecular tools for the mapping of the human genome. Prog Clin Biol Res (1985) 0.83

Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes. Mamm Genome (1997) 0.83

Human-mouse homologies in the region of the polycystic kidney disease gene (PKD1). Genomics (1992) 0.83

Mapping around the Fused locus on mouse chromosome 17. Mamm Genome (1995) 0.82

Saturating the region of the polycystic kidney disease gene with NotI linking clones. Am J Hum Genet (1991) 0.82

The human homologue of the ninjurin gene maps to the candidate region of hereditary sensory neuropathy type I (HSNI). Genomics (1998) 0.81

Radiation hybrid map spanning the Huntington disease gene region of chromosome 4. Genomics (1992) 0.81

Meiotic mapping of murine chromosome 17: the string of loci around l(17)-2Pas. Mamm Genome (1991) 0.81

cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases. Mamm Genome (1998) 0.80

Construction and regional localization of clones from a NotI linking library from human chromosome 17q. Genomics (1991) 0.80

Assay by polymerase chain reaction (PCR) of multi-allele polymorphisms in the Huntington's disease region of chromosome 4. Mol Cell Probes (1992) 0.80

Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene. Gene (1999) 0.79

Yeast artificial chromosomes for the molecular analysis of the familial polyposis APC gene region. Proc Natl Acad Sci U S A (1992) 0.78

Mouse cyclin F maps to a conserved linkage group on mouse chromosome 17. Mamm Genome (1995) 0.78

The mouse homologue of the tuberin gene (TSC2) maps to a conserved synteny group between mouse chromosome 17 and human 16p13.3. Genomics (1995) 0.78

Genetic analysis of colorectal cancer. Princess Takamatsu Symp (1989) 0.78

Purification of a phosphodiesterase from Bothrops atrox venom by affinity chromatography. Eur J Biochem (1973) 0.78

The mouse Rsk3 gene maps to the Leh66 elements carrying the t-complex responder Tcr. Mamm Genome (1999) 0.77

A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1). Genomics (1994) 0.77

Structural motifs of the PKD1 protein. Nephrol Dial Transplant (1996) 0.76

From phenotype to gene: molecular cloning in the Brachyury (T) locus region. Curr Top Microbiol Immunol (1988) 0.76

Haplotype analysis in autosomal dominant polycystic kidney disease. J Med Genet (1995) 0.75