Published in Biochemistry on January 23, 1979
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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25
The structural basis of ribosome activity in peptide bond synthesis. Science (2000) 18.82
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science (1992) 14.70
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Identifying nonpolar transbilayer helices in amino acid sequences of membrane proteins. Annu Rev Biophys Biophys Chem (1986) 11.00
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A unified polymerase mechanism for nonhomologous DNA and RNA polymerases. Science (1994) 7.98
The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesis. Cell (1981) 7.77
Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution. Science (1989) 7.35
Structure of catabolite gene activator protein at 2.9 A resolution suggests binding to left-handed B-DNA. Nature (1981) 7.33
Structural basis for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I: a two metal ion mechanism. EMBO J (1991) 7.16
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The structure of the E. coli recA protein monomer and polymer. Nature (1992) 5.77
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Structure of the recA protein-ADP complex. Nature (1992) 5.33
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Structure of a complex of catabolite gene activator protein and cyclic AMP refined at 2.5 A resolution. J Mol Biol (1987) 4.41
Fragments of the HIV-1 Tat protein specifically bind TAR RNA. Science (1990) 4.33
Sequence specificity in the dimerization of transmembrane alpha-helices. Biochemistry (1992) 4.19
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Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69. Cell (1997) 3.89
A mechanism for all polymerases. Nature (1998) 3.79
Structure of DNA polymerase I Klenow fragment bound to duplex DNA. Science (1993) 3.76
The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit. J Mol Biol (2004) 3.73
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A hypothesis on a specific sequence-dependent conformation of DNA and its relation to the binding of the lac-repressor protein. J Mol Biol (1979) 3.62
Structure of a transcribing T7 RNA polymerase initiation complex. Science (1999) 3.55
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Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex. Cell (1999) 3.52
Current models for the structure of biological membranes. J Cell Biol (1969) 3.47
X-ray diffraction studies of phase transitions in the membrane of Mycoplasma laidlawii. J Mol Biol (1970) 3.31
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Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase. Nature (1991) 3.21
Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit. Nature (1999) 3.20
The crystal structure of elongation factor G complexed with GDP, at 2.7 A resolution. EMBO J (1994) 3.18
The effect of point mutations on the free energy of transmembrane alpha-helix dimerization. J Mol Biol (1997) 3.16
Interhelical hydrogen bonding drives strong interactions in membrane proteins. Nat Struct Biol (2000) 3.12
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Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli. J Biol Chem (1990) 3.01
Structural basis for initiation of transcription from an RNA polymerase-promoter complex. Nature (1999) 2.97
The Calpha ---H...O hydrogen bond: a determinant of stability and specificity in transmembrane helix interactions. Proc Natl Acad Sci U S A (2001) 2.97
Crystal structure of the site-specific recombinase gamma delta resolvase complexed with a 34 bp cleavage site. Cell (1995) 2.92
Structural similarity in the DNA-binding domains of catabolite gene activator and cro repressor proteins. Proc Natl Acad Sci U S A (1982) 2.84
Structure of Taq polymerase with DNA at the polymerase active site. Nature (1996) 2.84
A dimerization motif for transmembrane alpha-helices. Nat Struct Biol (1994) 2.82
Lipid bilayer structure in the membrane of Mycoplasma laidlawii. J Mol Biol (1971) 2.81
TOXCAT: a measure of transmembrane helix association in a biological membrane. Proc Natl Acad Sci U S A (1999) 2.76
Crystal structure of a bacterial family-III cellulose-binding domain: a general mechanism for attachment to cellulose. EMBO J (1996) 2.74
Bacteriorhodopsin is an inside-out protein. Proc Natl Acad Sci U S A (1980) 2.72
Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1. Proc Natl Acad Sci U S A (1994) 2.71
Glucose-induced conformational change in yeast hexokinase. Proc Natl Acad Sci U S A (1978) 2.68
Crystal structure of Thermus aquaticus DNA polymerase. Nature (1995) 2.62
The planar organization of lecithin-cholesterol bilayers. J Biol Chem (1972) 2.62
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The geometry of the ribosomal polypeptide exit tunnel. J Mol Biol (2006) 2.53
Recombining the structures of HIV integrase, RuvC and RNase H. Structure (1995) 2.48
Massive outbreak of antimicrobial-resistant salmonellosis traced to pasteurized milk. JAMA (1987) 2.47
Polar residues drive association of polyleucine transmembrane helices. Proc Natl Acad Sci U S A (2001) 2.47
Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer. Proc Natl Acad Sci U S A (1994) 2.47
A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli. Science (1987) 2.43
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity. Proc Natl Acad Sci U S A (1984) 2.32
Crystal structure of unmodified tRNA(Gln) complexed with glutaminyl-tRNA synthetase and ATP suggests a possible role for pseudo-uridines in stabilization of RNA structure. Biochemistry (1994) 2.32
Crystal lattice packing is important in determining the bend of a DNA dodecamer containing an adenine tract. Proc Natl Acad Sci U S A (1989) 2.30
Structure of catabolite gene activator protein at 2.9-A resolution. Incorporation of amino acid sequence and interactions with cyclic AMP. J Biol Chem (1982) 2.27
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA. Nature (1995) 2.24
Modeling the cAMP-induced allosteric transition using the crystal structure of CAP-cAMP at 2.1 A resolution. J Mol Biol (2000) 2.23
Refolding of bacteriorhodopsin in lipid bilayers. A thermodynamically controlled two-stage process. J Mol Biol (1987) 2.23
Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate. Biochemistry (1993) 2.19
Crystal structure of the ribosomal RNA domain essential for binding elongation factors. Proc Natl Acad Sci U S A (1998) 2.18
The structure of carboxypeptidase a, vi. Some results at 2.0-a resolution, and the complex with glycyl-tyrosine at 2.8-a resolution. Proc Natl Acad Sci U S A (1967) 2.16
Two EGF molecules contribute additively to stabilization of the EGFR dimer. EMBO J (1997) 2.16
Computational searching and mutagenesis suggest a structure for the pentameric transmembrane domain of phospholamban. Nat Struct Biol (1995) 2.15
A 9 A resolution X-ray crystallographic map of the large ribosomal subunit. Cell (1998) 2.14
Spontaneous, pH-dependent membrane insertion of a transbilayer alpha-helix. Biochemistry (1997) 2.11
Structure of a complex between yeast hexokinase A and glucose. II. Detailed comparisons of conformation and active site configuration with the native hexokinase B monomer and dimer. J Mol Biol (1980) 2.09
Bacteriorhodopsin remains dispersed in fluid phospholipid bilayers over a wide range of bilayer thicknesses. J Mol Biol (1983) 2.07
Crystal structure of a DinB lesion bypass DNA polymerase catalytic fragment reveals a classic polymerase catalytic domain. Mol Cell (2001) 2.04
Screening surgeons for HIV infection: assessment of a potential public health program. Infect Control Hosp Epidemiol (1994) 2.03
Cleavage of the site-specific recombination protein gamma delta resolvase: the smaller of two fragments binds DNA specifically. Proc Natl Acad Sci U S A (1984) 2.02
The length of the flexible SNAREpin juxtamembrane region is a critical determinant of SNARE-dependent fusion. Mol Cell (1999) 1.99
Detergents modulate dimerization, but not helicity, of the glycophorin A transmembrane domain. J Mol Biol (1999) 1.94
Characterization of the plasma membrane of Mycoplasma laidlawii. I. Sodium dodecyl sulfate solubilization. Biochim Biophys Acta (1967) 1.90
Reverse transcriptase of human immunodeficiency virus can use either human tRNA(3Lys) or Escherichia coli tRNA(2Gln) as a primer in an in vitro primer-utilization assay. Proc Natl Acad Sci U S A (1992) 1.88
Structural basis for transfer RNA aminoacylation by Escherichia coli glutaminyl-tRNA synthetase. Biochemistry (1993) 1.88
Glycophorin A helical transmembrane domains dimerize in phospholipid bilayers: a resonance energy transfer study. Biochemistry (1994) 1.87
Structure of crystalline alpha-chymotrypsin. 3. Crystallographic studies of substrates and inhibitors bound to the active site of alpha-chymotrypsin. J Mol Biol (1969) 1.87
Characterization of the plasma membrane of Mycoplasma laidlawii. II. Modes of aggregation of solubilized membrane components. Biochim Biophys Acta (1967) 1.85