Published in Science on August 08, 1986
Separate measures of ATP utilization and recovery in human skeletal muscle. J Physiol (1993) 2.13
Production of hyperpolarized [1,4-13C2]malate from [1,4-13C2]fumarate is a marker of cell necrosis and treatment response in tumors. Proc Natl Acad Sci U S A (2009) 2.04
Mitochondrial membrane potential in single living adult rat cardiac myocytes exposed to anoxia or metabolic inhibition. J Physiol (1995) 1.76
Four-angle saturation transfer (FAST) method for measuring creatine kinase reaction rates in vivo. Magn Reson Med (2002) 1.58
Pharmacological plasticity of cardiac ATP-sensitive potassium channels toward diazoxide revealed by ADP. Proc Natl Acad Sci U S A (1999) 1.49
Skeletal muscle ATP kinetics are impaired in frail mice. Age (Dordr) (2013) 1.18
Quantitative studies of human cardiac metabolism by 31P rotating-frame NMR. Proc Natl Acad Sci U S A (1987) 1.15
Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy. J Clin Invest (1995) 1.11
Assessing the autopsy. Am J Pathol (1987) 1.11
Natural-abundance 13C NMR study of glycogen repletion in human liver and muscle. Proc Natl Acad Sci U S A (1989) 1.01
Magnetic resonance imaging with hyperpolarized [1,4-(13)C2]fumarate allows detection of early renal acute tubular necrosis. Proc Natl Acad Sci U S A (2012) 1.01
Phosphorus-31 magnetic resonance spectra reveal prolonged intracellular acidosis in the brain following subarachnoid hemorrhage. Proc Natl Acad Sci U S A (1994) 1.00
Observing the 1H NMR signal of the myoglobin Val-E11 in myocardium: an index of cellular oxygenation. Proc Natl Acad Sci U S A (1992) 0.95
Human primary brain tumour metabolism in vivo: a phosphorus magnetic resonance spectroscopy study. Br J Cancer (1989) 0.90
Three-dimensional mapping of the creatine kinase enzyme reaction rate in muscles of the lower leg. NMR Biomed (2013) 0.83
A phase II clinical and pharmacokinetic study of Lonidamine in patients with advanced breast cancer. Br J Cancer (1991) 0.80
Fatigability, Exercise Intolerance, and Abnormal Skeletal Muscle Energetics in Heart Failure. Circ Heart Fail (2017) 0.80
Resolution of creatine and phosphocreatine 1H signals in isolated human skeletal muscle using HR-MAS 1H NMR. Magn Reson Med (2008) 0.78
Real-time study of the urea cycle using 15N n.m.r. in the isolated perfused rat liver. Biochem J (1992) 0.78
Three-dimensional saturation transfer ³¹P-MRI in muscles of the lower leg at 3.0 T. Sci Rep (2014) 0.78
Biochemical changes within a multiple sclerosis plaque in vivo. J Neurol Neurosurg Psychiatry (1991) 0.77
Cardiac metabolism during exercise in healthy volunteers measured by 31P magnetic resonance spectroscopy. Br Heart J (1991) 0.76
Improving the physiological realism of experimental models. Interface Focus (2016) 0.75
Control of cardiac energetics: from models to human disease. MAGMA (2000) 0.75
Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochim Biophys Acta (1982) 7.13
Excessive intracellular acidosis of skeletal muscle on exercise in a patient with a post-viral exhaustion/fatigue syndrome. A 31P nuclear magnetic resonance study. Lancet (1984) 4.42
Observation of tissue metabolites using 31P nuclear magnetic resonance. Nature (1974) 4.13
Mapping of metabolites in whole animals by 31P NMR using surface coils. Nature (1980) 3.86
Bioenergetics of intact human muscle. A 31P nuclear magnetic resonance study. Mol Biol Med (1983) 3.40
Studies of acidosis in the ischaemic heart by phosphorus nuclear magnetic resonance. Biochem J (1979) 3.01
Examination of a case of suspected McArdle's syndrome by 31P nuclear magnetic resonance. N Engl J Med (1981) 3.00
A fluorescence probe of energy-dependent structure changes in fragmented membranes. Proc Natl Acad Sci U S A (1969) 2.22
Metabolic recovery after exercise and the assessment of mitochondrial function in vivo in human skeletal muscle by means of 31P NMR. Magn Reson Med (1984) 2.21
Brain biochemistry in Williams syndrome: evidence for a role of the cerebellum in cognition? Neurology (1998) 2.09
Phosphorus NMR studies on perfused heart. Biochem Biophys Res Commun (1977) 2.04
Insulin, ketone bodies, and mitochondrial energy transduction. FASEB J (1995) 1.95
Quantitative interpretation of bioenergetic data from 31P and 1H magnetic resonance spectroscopic studies of skeletal muscle: an analytical review. Magn Reson Q (1994) 1.84
Energetics of human muscle: exercise-induced ATP depletion. Magn Reson Med (1986) 1.83
Detection of low phosphocreatine to ATP ratio in failing hypertrophied human myocardium by 31P magnetic resonance spectroscopy. Lancet (1991) 1.82
The mitochondrial ATPase. Evidence for a single essential tyrosine residue. Eur J Biochem (1975) 1.80
NMR studies of tissue metabolism. Annu Rev Biochem (1981) 1.76
The reaction of 2,4,6-trinitrobenzenesulphonic acid with amino acids, Peptides and proteins. Biochem J (1968) 1.69
31p NMR saturation transfer measurements of the steady state rates of creatine kinase and ATP synthetase in the rat brain. FEBS Lett (1982) 1.68
Activity of phosphorylase in total global ischaemia in the rat heart. A phosphorus-31 nuclear-magnetic-resonance study. Biochem J (1981) 1.65
Active proton uptake by chromaffin granules: observation by amine distribution and phosphorus-31 nuclear magnetic resonance techniques. Biochemistry (1977) 1.63
Biochemical investigation of human tumours in vivo with phosphorus-31 magnetic resonance spectroscopy. Lancet (1986) 1.57
Phosphorus nuclear magnetic resonance studies on normoxic and ischemic cardiac tissue. Proc Natl Acad Sci U S A (1976) 1.57
The role of Na+/K+ ATPase activity during low flow ischemia in preventing myocardial injury: a 31P, 23Na and 87Rb NMR spectroscopic study. Magn Reson Med (1995) 1.53
The activity of creatine kinase in frog skeletal muscle studied by saturation-transfer nuclear magnetic resonance. Biochem J (1981) 1.53
Oral phosphate supplements reverse skeletal muscle abnormalities in a case of chronic fatigue with idiopathic renal hypophosphatemia. Neuromuscul Disord (1993) 1.46
A 31P-NMR saturation transfer study of the regulation of creatine kinase in the rat heart. Biochim Biophys Acta (1982) 1.46
Recent studies on cellular metabolism by nuclear magnetic resonance. Annu Rev Physiol (1979) 1.39
Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy. J Mol Cell Cardiol (1999) 1.38
Increased uncoupling proteins and decreased efficiency in palmitate-perfused hyperthyroid rat heart. Am J Physiol Heart Circ Physiol (2001) 1.37
31P NMR examination of two patients with NADH-CoQ reductase deficiency. Nature (1982) 1.37
Control of phosphocreatine resynthesis during recovery from exercise in human skeletal muscle. NMR Biomed (1993) 1.37
Comparisons of ATP turnover in human muscle during ischemic and aerobic exercise using 31P magnetic resonance spectroscopy. Magn Reson Med (1994) 1.35
Energy-coupling in adrenal chromaffin granules. Neuroscience (1976) 1.35
A new approach to metabolite compartmentation in muscle. Biochem Soc Trans (1976) 1.35
1-Anilinonaphthalene-8-sulphonate, a fluorescent conformational probe for glutamate dehydrogenase. Biochem J (1969) 1.34
The metabolic state of the rat liver in vivo measured by 31P-NMR spectroscopy. Biochim Biophys Acta (1986) 1.32
31P NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo. Biochemistry (1989) 1.32
Localization of metabolites in animals using 31P topical magnetic resonance. Nature (1980) 1.32
The reaction of glutamate dehydrogenase with 4-iodoacetamido salicylic acid. Eur J Biochem (1970) 1.30
Skeletal muscle bioenergetics in the chronic fatigue syndrome. J Neurol Neurosurg Psychiatry (1993) 1.30
Investigation of human mitochondrial myopathies by phosphorus magnetic resonance spectroscopy. Ann Neurol (1985) 1.29
Energy-linked activities of the chromaffin granule membrane. FEBS Lett (1975) 1.28
The steady-state rate of ATP synthesis in the perfused rat heart measured by 31P NMR saturation transfer. Biochem Biophys Res Commun (1981) 1.27
Frequency dependence of 31P NMR linewidths in sonicated phospholipid vesicles: effects of chemical shift anisotropy. FEBS Lett (1974) 1.27
Biochemical adaptation in the skeletal muscle of rats depleted of creatine with the substrate analogue beta-guanidinopropionic acid. Biochem J (1985) 1.25
Physical training improves skeletal muscle metabolism in patients with chronic heart failure. J Am Coll Cardiol (1993) 1.24
Adenosine triphosphate-evoked catecholamine release in chromatin granules. Osmotic lysis as a consequence of proton translocation. Biochem J (1976) 1.22
Studies of metabolism in the isolated, perfused rat heart using 13C NMR. FEBS Lett (1981) 1.22
Nuclear magnetic resonance studies of forearm muscle in Duchenne dystrophy. Br Med J (Clin Res Ed) (1982) 1.21
Enzyme and membrane conformation in biochemical control. Biochem J (1971) 1.21
Analysis of rat heart in vivo by phosphorus nuclear magnetic resonance. Proc Natl Acad Sci U S A (1980) 1.20
Probes for the conformational transitions of phosphorylase b. Effect of ligands studied by proton relaxation enhancement, fluorescence and chemical reactivities. Eur J Biochem (1971) 1.19
Membrane studies with polarity-dependent and excimer-forming fluorescent probes. Biochem J (1970) 1.19
The production, buffering and efflux of protons in human skeletal muscle during exercise and recovery. NMR Biomed (1993) 1.19
Application of 31P NMR to model and biological membrane systems. FEBS Lett (1975) 1.19
Is a high glycogen content beneficial or detrimental to the ischemic rat heart? A controversy resolved. Circ Res (1996) 1.19
Nitric oxide stimulates glucose transport and metabolism in rat skeletal muscle in vitro. Biochem J (1997) 1.18
Muscle metabolism in patients with peripheral vascular disease investigated by 31P nuclear magnetic resonance spectroscopy. Clin Sci (Lond) (1986) 1.17
Conformational changes and the regulation of glutamate-dehydrogenase activity. Biochem J (1966) 1.16
Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR--an activator of AMP-activated protein kinase. FEBS Lett (1996) 1.16
Quantitative studies of human cardiac metabolism by 31P rotating-frame NMR. Proc Natl Acad Sci U S A (1987) 1.15
Bioenergetic processes in chromaffin granules a new perspective on some old problems. Biochim Biophys Acta (1978) 1.14
Ageing: effects on oxidative function of skeletal muscle in vivo. Mol Cell Biochem (1997) 1.13
The effect of uncouplers on catecholamine incorporation by vesicles of chromaffin granules. Biochem J (1975) 1.13
A model kidney transplant studied by phosphorus nuclear magnetic resonance. Biochem Biophys Res Commun (1977) 1.12
Study of hereditary fructose intolerance by use of 31P magnetic resonance spectroscopy. Lancet (1987) 1.12
Interaction of glutamate dehydrogenase with fluorescent dyes. Biochem Biophys Res Commun (1967) 1.11
NMR studies on phospholipid bilayers. Some factors affecting lipid distribution. Biochim Biophys Acta (1975) 1.10
Role of phosphocreatine in energy transport in skeletal muscle of bullfrog studied by 31P-NMR. Biochim Biophys Acta (1990) 1.10
Cardiac and skeletal muscle insulin resistance in patients with coronary heart disease. A study with positron emission tomography. J Clin Invest (1996) 1.10
Phospholipid bilayer contribution to 31P NMR spectra in vivo. Magn Reson Med (1989) 1.10
Kinetic control of mitochondrial ATP synthesis. Biochemistry (1986) 1.08
Determination of buffering capacity of rat myocardium during ischemia. Biochim Biophys Acta (1988) 1.07
Mitral regurgitation: impaired systolic function, eccentric hypertrophy, and increased severity are linked to lower phosphocreatine/ATP ratios in humans. Circulation (1998) 1.07
The effects of insulin on myocardial metabolism and acidosis in normoxia and ischaemia. A 31P-NMR study. Biochim Biophys Acta (1982) 1.07
Quantitative analysis by 31P magnetic resonance spectroscopy of abnormal mitochondrial oxidation in skeletal muscle during recovery from exercise. NMR Biomed (1994) 1.06
Assessment of human liver metabolism by phosphorus-31 magnetic resonance spectroscopy. Br J Radiol (1986) 1.05
Cellular energetics of dystrophic muscle. J Neurol Sci (1993) 1.05
Differential scanning calorimetry and 31P NMR studies on sonicated and unsonicated phosphatidylcholine liposomes. Biochim Biophys Acta (1975) 1.04
An investigation of arterial insufficiency in rat hindlimb. A combined 31P-n.m.r. and bloodflow study. Biochem J (1986) 1.04
A 31P-nuclear magnetic resonance study of skeletal muscle metabolism in rats depleted of creatine with the analogue beta-guanidinopropionic acid. Biochim Biophys Acta (1984) 1.03
The ATPase inhibitor protein in oxidative phosphorylation. The rate-limiting factor to phosphorylation in submitochondrial particles. Biochim Biophys Acta (1979) 1.03
The effect of fatty acids on the surface potential of phospholipid vesicles measured by condensed phase radioluminescence. Biochim Biophys Acta (1981) 1.03
Phosphorus nuclear-magnetic-resonance studies of compartmentation in muscle. Biochem J (1978) 1.02
The utilisation of creatine and its analogues by cytosolic and mitochondrial creatine kinase. Biochim Biophys Acta (1996) 1.01
Imaging of human brain creatine kinase activity in vivo. FASEB J (1989) 1.01
Regulation of creatine kinase during steady-state isometric twitch contraction in rat skeletal muscle. Biochim Biophys Acta (1984) 1.01
Specificity of nucleotide binding and coupled reactions utilising the mitochondrial ATPase. Biochim Biophys Acta (1978) 1.01
Measurement and interpretation of fluorescence polarisations in phospholipid dispersions. Biochim Biophys Acta (1976) 1.00
Phosphorus-31 magnetic resonance spectra reveal prolonged intracellular acidosis in the brain following subarachnoid hemorrhage. Proc Natl Acad Sci U S A (1994) 1.00
Clinical aspects on 31P NMR spectroscopy. Br Med Bull (1984) 1.00
The chemistry of flavines and flavorproteins. Photoreduction of flavines by amino acids. Biochem J (1968) 1.00
N.m.r. studies of metabolism in perfused organs. Philos Trans R Soc Lond B Biol Sci (1980) 1.00
Is lactate-induced myocardial ischaemic injury mediated by decreased pH or increased intracellular lactate? J Mol Cell Cardiol (1995) 0.99
Potential and limitations of nuclear magnetic resonance for the cardiologist. Br Heart J (1983) 0.99
The mitochondrial ATPase. Selective modification of a nitrogen residue in the beta subunit. Eur J Biochem (1975) 0.99
Allosteric transitions of glutamate dehydrogenase. Nature (1968) 0.99
Total ion content of skeletal and cardiac muscle in the mdx mouse dystrophy: Ca2+ is elevated at all ages. J Neurol Sci (1991) 0.98